CoVIC ID Antibody information Antibody features Affinity, KD (M) - Duke Pseudovirus neutralization (PNV-Luciferase; ng/mL) Pseudovirus neutralization - Beta (PNV-Luciferase; ng/mL) Pseudovirus neutralization - Delta (PNV-Luciferase; ng/mL) Authentic virus neutralization (Auth-luciferase ng/mL) - UNC Authentic virus neutralization (Auth-mNeonGreen ng/mL) - UTMB In vivo protection survival (%) Fc Activity - Ragon Complex formation inhibition (%) Antibody dependent enhancement UTMB - ADMP sequence / structural features Nexelis - PK UTMB - ADNKA Pseudovirus neutralization (PNV-GFP; % infected cells) Epitope Community (Full-length) Details
Unblinded ID Organization Isotype Epitope Community (RBD) D614 D614G RBD NTD B.1.351 Omicron IC50- Pseudovirus neutralization (ng/mL) IC80- Pseudovirus neutralization (ng/mL) IC90- Pseudovirus neutralization (ng/mL) IC50- Pseudovirus neutralization, Beta (ng/mL) IC80- Pseudovirus neutralization, Beta (ng/mL) IC90- Pseudovirus neutralization, Beta(ng/mL) IC50- Pseudovirus neutralization, Delta (ng/mL) IC80- Pseudovirus neutralization, Delta (ng/mL) IC90- Pseudovirus neutralization, Delta (ng/mL) IC50 (WA-1)- Authentic virus neutralization, UNC (ng/mL) IC80 (WA-1)- Authentic virus neutralization, UNC (ng/mL) IC90 (WA-1)- Authentic virus neutralization, UNC (ng/mL) IC50 (B.1.351)- Authentic virus neutralization, UNC (ng/mL) IC80 (B.1.351)- Authentic virus neutralization, UNC (ng/mL) IC50- UTMB - Authentic virus neutralization, UTMB (ng/mL) IC80- UTMB - Authentic virus neutralization, UTMB (ng/mL) IC90- UTMB - Authentic virus neutralization, UTMB (ng/mL) K18 mice hamsters ADCP mADCP ADNP mADNP ADCD (MFI C3) ADNKA % CD107a+ ADNKA % MIP-1b+ FcgR2aR (MFI) FcgR3aV (MFI) FcgR2b (MFI) FcgR3b (MFI) FcRn (MFI) mFcR2 (MFI) mFcR3 (MFI) mFcR4 (MFI) Spike: ACE2 Score (for level of ADE at 10 ug/mL) IC50- Antibody dependent enhancement IC80- Antibody dependent enhancement IC90- Antibody dependent enhancement Fold increase over virus control Escape Structure GMC for Pre-Spike IgG GMC for RBD IgG % CD107a+ Fold-change CD107a+ % IFNg+ Fold-change CD107a+ % TNFa+ Fold-change TNFa+ PNV-G (%infected; 250 ng/ml) PNV-G BETA (% infected; 250 ng/ml) PNV-L DELTA (IC50 ng/ml) PNV-G DELTA (%infected; 250 ng/ml) PNV-G BA.1 (%infected; 250 ng/ml) PNV-G BA.1.1 (%infected; 250 ng/ml) PNV-G BA.2 (%infected; 250 ng/ml) Community
CC12.3 None 5035 16232 54.642857142857146 1.4
Untreated Infected Control None None
Mock Infected Control None None
mAb-251 None 0.0
CR3022 None moderate weak weak moderate weak strong strong 5.99 6.11 4.78 5.73 3.94 5.12 5.3 6.16 nt nt nt nt nt nt nt D
KZ52 None weak moderate weak strong weak weak weak 4.06 3.84 4.38 3.7 3.78 3.59 4.4 4.29
negative plasma None weak moderate weak weak strong weak weak 4.01 3.79 4.33 3.7 3.76 3.58 4.33 4.2
CC12.14 None 1299 4989 2.1
1 IgG1 1 1.63e-09 1.75e-10 1.46e-06 4.19e-08 1830.0 6370.0 14100.0 2430.0 2510.0 2530.0 202.0 >25000 >25000 245 662 1.24e+03 1.65e+03 1.95e+03 weak moderate weak strong moderate weak moderate 6.09 6.05 5.48 4.83 3.5 3.93 4.87 5.66 69.6 1.2 20.50 0.90 1.32 1.02 0.05 0.06 54 100 202 14 91 100 100
2 IgG1 2b 1.24e-10 5.16e-11 1.23e-07 1.33e-11 1470.0 4010.0 7910.0 20.6 89.3 209.0 >25000 >25000 >25000 19 60 3.03e+02 4.69e+02 6.05e+02 10.0 strong strong strong strong moderate moderate moderate 6.34 6.28 6.01 6.42 5.65 5.96 5.89 6.63 100.0 2.0 Y489H 0.5mg/kg: 2065.60|1.5mg/kg: 7474.30 30.10 1.31 1.20 0.92 0.73 0.85 4 2 25000 92 94 100 93 H2
3 IgG1 2c 1.47e-09 8.3e-10 8.93e-07 2320.0 8360.0 16000.0 705.0 2850.0 4420.0 >25000 >25000 >25000 846 2766 3.20e+03 6.50e+03 9.84e+03 0.0 weak weak weak strong weak moderate moderate 5.87 5.99 5.0 4.39 3.63 3.94 4.68 5.03 90.3 1.12 1.5mg/kg: 1527.28 13.15 0.57 0.77 0.59 0.42 0.49 43 99 25000 13 95 100 84 H2
4 IgG1 2d 2.43e-10 8.05e-11 1.11e-07 1.84e-08 709.0 2480.0 5020.0 1530.0 1560.0 1570.0 759.0 5560.0 >25000 179 450 1.49e+03 2.73e+03 3.88e+03 moderate weak weak strong weak moderate weak 6.21 6.23 5.66 5.54 4.92 3.95 4.76 5.47 100.0 1.07 27.90 1.22 1.17 0.90 0.52 0.60 56 100 759 49 88 95 96 H2
5 IgG1 2c 1.08e-09 8.64e-10 3.98e-07 853.0 2600.0 5260.0 29.8 186.0 406.0 158.0 415.0 679.0 433 754 1.57e+04 1.84e+04 2.02e+04 0.0 weak weak weak moderate weak moderate moderate 6.05 6.08 5.36 5.14 4.56 3.94 4.77 5.14 98.2 1.23 1.5mg/kg: 1243.76 15.65 0.68 1.36 1.05 0.04 0.05 19 100 158 5 78 91 100 H2
6 IgG1 2a 5.53e-10 3.53e-10 8.71e-08 5.98e-10 >25000 >25000 >25000 >25000 >25000 >25000 21.4 102.0 249.0 11861 22679 2.52e+02 4.86e+02 7.14e+02 moderate moderate weak weak moderate moderate weak 6.05 5.94 5.65 5.87 4.09 4.59 5.11 5.91 99.0 1.28 22.65 0.99 1.34 1.03 0.89 1.03 91 100 21.4 59 81 96 98 A
7 IgG1 6b 1.21e-10 3.66e-11 1.72e-08 4.5e-06 4.92e-09 53.8 146.0 261.0 >25000 >25000 >25000 >25000 >25000 >25000 18 33 2.50e+04 2.50e+04 2.50e+04 10.0 moderate moderate moderate moderate weak moderate weak 6.09 6.0 5.71 5.98 4.58 4.57 4.92 6.15 100.0 2.51 0.5mg/kg: 1789.63|1.5mg/kg: 7481.71 21.40 0.93 1.57 1.21 0.07 0.08 3 100 25000 0 90 95 91 H1
8 IgG1 6b 6.75e-10 4.51e-10 2.36e-08 1.34e-10 12800.0 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2191 6355 1.02e+04 1.13e+04 1.21e+04 moderate weak moderate weak weak moderate weak 6.34 6.28 6.01 6.38 5.35 5.49 5.22 6.41 98.0 2.85 22.90 1.00 1.62 1.25 0.03 0.03 91 98 25000 56 86 96 83 A
9 IgG1 2c 1.65e-11 7.06e-12 2.33e-10 9.29e-08 3.63e-11 2.13e-08 12.6 24.0 34.1 >25000 >25000 >25000 1140.0 1170.0 1170.0 <0.32 0.54 3035 4766 4.83e+00 8.61e+00 1.21e+01 None weak weak weak moderate weak moderate weak 3.75 3.75 3.67 3.72 3.45 3.87 4.18 4.64 100.0 1.96 0.5mg/kg: 2099.34 23.45 1.02 1.18 0.90 0.14 0.17 0 93 1140 5 88 97 88 H3
10 IgG1 2c 1.84e-11 8.3e-12 2.04e-10 8.55e-08 3.92e-11 3.14e-08 10.1 21.2 32.7 464.0 2300.0 7470.0 51.2 325.0 907.0 <0.32 1 5862 15389 1.18e+01 2.19e+01 3.15e+01 None weak weak weak weak weak weak weak 3.78 3.74 3.7 3.71 3.46 3.86 4.26 4.24 100.0 1.29 0.5mg/kg: 3133.56 21.10 0.92 1.36 1.05 0.12 0.13 0 100 51.2 6 100 94 85 H3
11 IgG1 2c 2.35e-11 9.87e-12 2.11e-10 4.67e-08 2.81e-11 4.85e-09 6.09 16.2 28.0 >25000 >25000 >25000 159.0 656.0 1520.0 <0.32 0.93 137 196 1.78e+01 2.62e+01 3.28e+01 90.0 weak moderate weak moderate weak moderate weak 3.86 3.77 3.74 3.69 3.45 3.89 4.09 4.16 99.4 0.893 0.5mg/kg: 2060.71|1.5mg/kg: 8050.89 34.05 1.49 1.30 1.00 1.01 1.18 1 6 159 1 97 100 100 H3
12 IgG1 2c 1.11e-11 5.07e-12 1.64e-10 7.55e-08 4.24e-11 3.66e-08 7.48 18.6 30.6 990.0 1190.0 1250.0 352.0 1050.0 1450.0 <0.32 <0.32 2526 4536 8.62e+00 1.43e+01 1.93e+01 None weak strong weak strong weak moderate weak 3.67 3.75 3.62 3.71 3.45 3.88 4.14 4.2 100.0 2.42 0.5mg/kg: 2732.99 21.50 0.94 1.41 1.08 0.05 0.06 1 70 352 10 100 100 90 H3
13 IgG1 2c 8.95e-12 4.71e-12 1.16e-10 5.11e-08 2.42e-11 6.07 15.4 25.3 71.7 235.0 459.0 19.4 54.8 97.5 <0.32 0.85 159 627 4.75e+00 7.05e+00 8.88e+00 70.0 weak weak weak strong weak moderate moderate 4.04 4.43 3.8 3.72 3.48 3.91 4.82 4.76 100.0 3.3 0.5mg/kg: 4115.36|1.5mg/kg: 10520.90 9.65 0.42 2.07 1.59 0.47 0.55 1 41 19.4 1 98 90 92 H3
14 IgG1 2d 4.43e-11 1.1e-11 1.94e-09 1.14e-06 5.3e-11 5.45e-08 9.75 24.7 42.9 >25000 >25000 >25000 373.0 1490.0 7440.0 <0.32 <0.32 >12500 >12500 6.70e-01 1.42e+00 2.21e+00 strong strong strong strong moderate moderate strong 6.37 6.32 6.02 6.46 5.71 5.99 5.74 6.6 100.0 3.49 30.05 1.31 0.97 0.75 0.76 0.88 84 100 373 94 95 83 72 H3
15 IgG1 2d 9.47e-11 4.56e-11 1.19e-08 1.19e-07 1.22e-09 2.88e-09 32.0 107.0 223.0 >25000 >25000 >25000 1610.0 3140.0 3780.0 1 10 >12500 >12500 3.12e+01 4.93e+01 6.44e+01 strong strong strong strong strong moderate moderate 6.38 6.33 6.04 6.45 5.74 6.08 5.86 6.63 100.0 3.63 22.45 0.98 1.43 1.10 0.07 0.09 1 100 1610 28 80 85 79 H2
16 IgG1 2a 1.57e-10 5.04e-11 5.31e-09 1.03e-06 7.34e-10 9.66e-09 44.5 180.0 388.0 995.0 >25000 >25000 215.0 888.0 1380.0 10518 >25000 1.61e+04 8.58e+04 2.28e+05 moderate weak weak strong weak moderate moderate 6.15 6.15 5.36 3.9 5.09 3.94 4.91 5.04 100.0 1.54 83 100 215 56 89 84 78 H2
17 IgG1 4b 5.04e-10 4.01e-10 3.46e-08 1.81e-10 2.82e-09 1030.0 3020.0 5630.0 >25000 >25000 >25000 >25000 >25000 >25000 8726 24853 2.50e+04 2.50e+04 2.50e+04 strong moderate moderate moderate moderate moderate moderate 6.33 6.28 5.99 6.4 5.49 5.67 5.66 6.51 67.0 5.79 20.55 0.90 1.44 1.10 0.09 0.10 74 98 25000 83 79 74 74 G
18 IgG
19 IgG 1.08e-09 1.18e-09 2.64e-08 39.7 140.0 262.0 664.0 >25000 >25000 >25000 >25000 >25000 433 1516 2.50e+04 2.50e+04 2.50e+04 weak weak weak moderate weak moderate weak 4.07 3.8 3.83 3.73 3.45 3.93 4.75 4.54 23.7 1.42
20 IgG1 7.59e-10 8.13e-10 8.15e-08 1.36e-09 2.32e-09 72.3 587.0 >25000 639.0 1160.0 1350.0 >25000 >25000 >25000 236 4924 2.59e+03 9.47e+03 2.02e+04 10.0 strong moderate moderate strong strong moderate strong 6.09 6.0 5.77 6.02 4.23 4.57 5.23 6.07 9.0 3.64 0.5mg/kg: 50.30|1.5mg/kg: 58.71 24.15 1.05 1.61 1.24 0.14 0.16 12 100 25000 84 90 83 79
21 IgG1 7c 5.02e-10 1.4e-09 2.08e-10 5.25e-10 9.26e-09 12500.0 >25000 >25000 162.0 >25000 >25000 >25000 >25000 >25000 8582 20807 1.99e+04 3.48e+04 4.82e+04 0.0 strong moderate moderate moderate moderate moderate weak 6.29 6.22 5.95 6.3 5.2 5.14 5.34 6.28 11.6 2.69 0.5mg/kg: 134.98|1.5mg/kg: 643.01 40.20 1.76 2.06 1.58 0.51 0.59 99 100 25000 81 91 96 77
22 IgG1 6a 1.08e-09 3e-09 1.04e-07 3.68e-10 1.84e-08 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 0.0 strong weak moderate weak weak moderate weak 6.24 6.2 5.89 6.22 5.0 4.63 5.2 6.11 51.1 2.95 1.5mg/kg: 1601.37 12.20 0.53 6.80 5.23 0.73 0.85 90 100 25000 71 97 100 79
23 IgG1 5b 3.72e-10 5.86e-10 7.13e-08 2e-10 4.25e-09 14200.0 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 0.0 strong moderate moderate weak moderate moderate weak 6.27 6.22 5.93 6.27 4.82 5.04 5.09 6.27 36.3 5.49 1.5mg/kg: 158.53 18.15 0.79 1.63 1.25 0.12 0.13 87 100 25000 87 90 90 82 E4
24 IgG1 7b 1.21e-09 2.3e-09 1.46e-08 7.49e-10 2.55e-08 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 14175 >25000 2.50e+04 2.50e+04 2.50e+04 0.0 moderate strong weak weak weak strong moderate 6.22 6.18 5.86 6.23 5.08 4.78 5.17 6.21 48.7 3.48 1.5mg/kg: 3119.58 33.00 1.44 0.84 0.65 1.14 1.33 100 100 25000 86 98 100 91
25 IgG1 7b 1.07e-09 1.9e-09 8.49e-08 6.96e-09 8.2e-08 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 moderate moderate strong moderate weak moderate moderate 5.77 5.93 5.07 5.59 3.78 4.02 4.91 5.71 31.2 2.47 21.40 1.15 1.68 5.00 0.63 1.05 89 100 25000 98 100 95 95
26 IgG1 7b 6.57e-10 1.18e-09 3.88e-08 5.36e-09 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 0.0 strong weak moderate strong weak moderate moderate 6.22 6.14 5.81 6.16 4.75 4.54 5.25 6.14 31.8 5.8 1.5mg/kg: 630.67 19.20 1.04 0.84 2.52 0.46 0.76 82 99 25000 85 89 95 100
27 IgG1 3a 3.59e-09 1.42e-09 1.48e-07 2.62e-10 8.91e-08 8250.0 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 260 2457 1173 4632 2.07e+04 3.24e+04 4.22e+04 strong moderate moderate strong weak moderate moderate 6.19 6.13 5.87 6.24 5.23 5.04 5.3 6.34 88.6 6.13 24.55 1.32 1.69 5.04 0.61 1.02 72 92 25000 68 80 90 89 A
28 IgG1 6b 3.3e-10 5.22e-10 1.23e-08 1.26e-10 2.32e-08 512.0 1960.0 3960.0 755.0 1400.0 1760.0 308.0 >25000 >25000 190 815 398 897 3.19e+03 4.68e+03 5.85e+03 0.0 strong moderate moderate strong weak moderate moderate 6.36 6.3 6.02 6.42 5.63 5.9 5.61 6.55 100.0 6.13 0.5mg/kg: 1908.96|1.5mg/kg: 3954.73 27.10 1.46 1.84 5.49 0.67 1.12 57 65 308 37 75 86 84 A
29 IgG1 4.33e-10 3.5e-10 3.99e-07 1020.0 1520.0 1750.0 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 moderate weak weak strong weak moderate weak 6.24 6.18 5.89 6.2 4.64 4.74 5.15 6.16 5.0 19.25 1.04 0.77 2.28 0.68 1.13 84 100 25000 77 81 84 77 E2
30 IgG1 2d 3.21e-11 5.94e-12 4.1e-09 2.73e-06 8.87 26.8 50.7 518.0 1650.0 >25000 47.1 113.0 200.0 2 6 >25000 >25000 2.75e+01 5.23e+01 7.61e+01 100.0 strong strong strong moderate moderate moderate moderate 6.36 6.3 6.02 6.45 5.72 6.06 5.53 6.59 100.0 7.37 E484A 0.5mg/kg: 2456.41|1.5mg/kg: 8195.59 25.45 1.37 1.31 3.91 0.59 0.99 0 100 47.1 3 74 80 81 H3
31 IgG1 4b 1.42e-10 8.08e-11 7.02e-08 3.96e-10 11400.0 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 949 2233 1.21e+04 4.33e+04 9.12e+04 10.0 strong weak moderate moderate moderate moderate moderate 6.3 6.26 5.97 6.4 5.68 6.03 5.67 6.6 99.0 2.57 1.5mg/kg: 2850.55 24.85 1.34 0.96 2.87 0.80 1.33 74 100 25000 52 83 79 78 G
32 IgG1 2d 5.76e-11 1.85e-11 1.76e-09 1.96e-06 2.04e-10 8.66 32.3 66.4 >25000 >25000 >25000 1.08 1.06 1.06 2 8 735 2676 6.11e+01 1.44e+02 2.37e+02 60.0 strong strong strong moderate moderate moderate weak 6.39 6.32 6.05 6.46 5.72 6.08 5.68 6.61 100.0 2.65 G496V|S494L 0.5mg/kg: 3150.21|1.5mg/kg: 6774.03 26.20 1.41 0.74 2.22 0.78 1.29 0 89 1.08 73 83 80 72 H3
33 IgG1 3.32e-08 1.63e-08 4.8e-06 8.18e-08 >25000 >25000 >25000 >25000 >25000 >25000 5650.0 7400.0 7930.0 18 44 259 637 4.57e+03 6.06e+03 7.14e+03 10.0 strong weak weak weak weak moderate moderate 4.35 4.01 3.81 3.77 3.48 3.94 4.91 5.23 7.6 3.29 24.30 1.31 0.56 1.67 0.91 1.52 46 100 5650 81 86 81 70
34 IgG1 2.37e-09 1.74e-09 3.92e-09 5.29e-08 162.0 453.0 1050.0 1.13 1.12 1.12 >25000 >25000 >25000 201 19356 1.02e+04 2.14e+04 3.30e+04 0.0 moderate moderate weak weak weak moderate strong 6.0 5.97 5.52 5.7 4.31 4.12 5.01 5.71 6.4 2.3 1.5mg/kg: 50.30 19.80 1.07 0.84 2.51 0.94 1.57 14 99 25000 75 86 72 74
35 IgG1 7c 1.68e-09 1.05e-09 2.81e-09 4.34e-10 2.3e-08 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 0.0 strong strong moderate weak weak moderate weak 6.21 6.2 5.9 6.25 5.33 5.21 5.31 6.22 7.1 3.24 1.5mg/kg: 1842.61 24.50 1.32 0.76 2.25 0.59 0.99 90 100 25000 80 94 82 74
36 IgG1 4.36e-09 4.96e-09 9.51e-07 86.2 6600.0 >25000 >25000 >25000 >25000 >25000 >25000 >25000 4 14 >25000 >25000 3.07e+01 1.18e+02 2.59e+02 60.0 moderate moderate weak weak weak moderate weak 6.18 6.11 5.87 6.18 5.04 5.07 5.06 6.21 3.1 del68-70 0.5mg/kg: 63.45 23.85 1.29 0.61 1.82 0.15 0.25 30 100 25000 85 100 84 87
37 IgG1 1.9e-08 3.96e-08 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 moderate moderate weak weak weak moderate weak 5.19 5.28 4.44 4.15 3.53 3.92 4.86 5.2 3.9 0.459 22.15 1.19 0.64 1.91 1.16 1.93 87 100 25000 90 98 92 100
38 IgG 6b 1.09e-09 4.54e-10 7.05e-09 1.4e-10 297.0 1310.0 2900.0 863.0 2170.0 2740.0 376.0 1820.0 2920.0 16 78 41 123 3.45e+02 7.16e+02 1.10e+03 None moderate moderate moderate strong moderate moderate strong 6.35 6.3 6.01 6.42 5.52 5.76 5.48 6.45 99.3 1.05 0.5mg/kg: 176.64 21.40 1.15 0.59 1.76 0.54 0.90 31 24 376 7 92 90 87 A
39 IgG 2d 3.12e-11 1.06e-11 1.78e-09 1.66e-06 3.33e-08 4.13e-08 7.11 20.1 35.8 >25000 >25000 >25000 124.0 333.0 750.0 <0.32 <0.32 12500 12500 1.66e+01 2.68e+01 3.56e+01 None strong strong strong strong moderate moderate moderate 6.36 6.32 6.03 6.47 5.71 6.01 5.7 6.61 100.0 1.47 L452P 0.5mg/kg: 3296.86 24.60 1.33 0.98 2.94 0.86 1.43 0 100 124 6 82 91 82 H3
40 IgG 2d 7.15e-11 3.82e-11 1.68e-08 6.92e-09 4.03e-08 248.0 825.0 1590.0 >25000 >25000 >25000 289.0 1540.0 3400.0 76 216 >25000 >25000 4.76e+02 1.46e+03 2.80e+03 None strong moderate strong strong weak moderate moderate 6.37 6.31 6.03 6.45 5.71 6.06 5.82 6.63 100.0 0.868 F490C|F490L|F490V 0.5mg/kg: 1926.61 18.80 1.01 0.47 1.42 0.91 1.52 24 85 289 9 87 90 87 H3
41 IgG1 2.33e-10 2.49e-10 2.75e-08 1.06e-10 7.77e-10 6450.0 23200.0 >25000 >25000 >25000 >25000 >25000 >25000 >25000 5997 >25000 2.50e+04 2.50e+04 2.50e+04 100.0 strong weak moderate moderate weak moderate weak 6.3 6.25 5.95 6.35 5.51 5.6 4.6 6.36 1.02 1.5mg/kg: 15897.03 23.00 1.24 0.66 1.97 1.05 1.76 82 100 25000 70 89 82 88
42 IgG1 2a 4.84e-10 1.59e-10 1.1e-08 4.47e-10 57.6 185.0 348.0 1000.0 21700.0 >25000 13.8 53.8 124.0 14 44 2246 6637 7.81e+02 1.81e+03 2.95e+03 0.0 strong moderate strong moderate moderate moderate moderate 6.37 6.3 6.02 6.45 5.61 5.87 5.44 6.56 98.8 0.626 0.5mg/kg: 3894.89 21.45 1.16 0.41 1.22 0.40 0.67 6 74 13.8 1 83 95 81 H1
43 IgG4 2c 1.94e-10 9.59e-11 2.27e-08 1.48e-08 34.1 109.0 210.0 >25000 >25000 >25000 3.2 17.5 47.5 13 31 1672 3234 1.22e+03 2.06e+03 2.81e+03 10.0 strong weak moderate weak weak moderate moderate 6.38 6.11 6.01 3.8 5.72 4.02 4.25 4.98 100.0 0.718 0.5mg/kg: 206.34|1.5mg/kg: 778.93 22.20 1.20 0.82 2.46 0.83 1.39 0 100 3.2 1 90 85 75
44 IgG1 2c 1.42e-10 1.98e-10 4.74e-08 53.4 163.0 302.0 >25000 >25000 >25000 102.0 265.0 432.0 5 19 >25000 >25000 4.26e+02 1.01e+03 1.66e+03 30.0 strong moderate moderate moderate weak moderate weak 6.3 6.24 5.98 6.4 5.61 5.94 5.57 6.53 100.0 1.41 1.5mg/kg: 1312.88 24.15 1.30 0.78 2.31 0.80 1.33 2 100 102 1 77 88 65
45 IgG4 2c 1.7e-10 3.6e-11 3.67e-08 8.06 27.7 55.2 >25000 >25000 >25000 5.47 28.6 68.7 2 8 >25000 >25000 1.04e+02 1.56e+02 1.98e+02 30.0 moderate weak moderate weak weak moderate weak 6.37 6.2 6.02 3.82 5.69 4.03 4.29 5.44 100.0 1.85 0.5mg/kg: 372.94|1.5mg/kg: 1152.88 18.90 1.02 0.66 1.96 0.72 1.20 2 100 5.47 1 74 75 63
46 IgG1 2.98e-09 3.14e-08 >25000 >25000 >25000 2230.0 3430.0 3800.0 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 weak moderate weak weak weak moderate weak 4.14 3.92 3.84 3.72 3.5 3.9 4.85 5.39 6.5 1.23 35.20 1.90 0.76 2.27 0.63 1.05 94 100 2230 74 88 82 70
47 IgG4 2.73e-09 3.18e-09 3.55e-08 4610.0 11000.0 18900.0 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 weak moderate weak weak weak moderate weak 4.54 4.86 3.98 4.25 3.69 3.92 4.85 4.63 24.4 2.53 T588A 23.10 1.25 0.59 1.76 0.94 1.57 90 100 25000 77 91 74 81
48 IgG1 2a 4.28e-10 1.51e-10 1.22e-07 2.19e-08 1150.0 3620.0 13300.0 >25000 >25000 >25000 115.0 696.0 >25000 426 1028 2.82e+03 4.63e+03 6.18e+03 moderate moderate weak weak weak moderate weak 6.22 6.17 5.86 6.22 4.61 4.46 5.02 6.13 100.0 3.14 23.35 1.26 1.07 3.19 0.52 0.86 57 100 115 9 98 77 81
49 IgG4 2a 3.41e-10 1.36e-10 1.48e-07 1.39e-08 57.4 219.0 506.0 2540.0 3720.0 4100.0 35.7 133.0 259.0 110 256 2.24e+03 9.30e+03 2.14e+04 0.0 moderate moderate moderate weak weak weak weak 6.13 5.75 5.88 3.74 5.57 3.98 4.58 4.61 100.0 2.67 1.5mg/kg: 1233.73 23.80 1.28 0.92 2.75 0.58 0.97 26 100 35.7 2 99 91 91
50 IgG1 2a 4.68e-10 1.75e-10 7.87e-08 1.89e-08 869.0 3110.0 6470.0 >25000 >25000 >25000 116.0 398.0 1480.0 70 322 >25000 >25000 4.58e+03 1.11e+04 1.87e+04 strong weak moderate strong weak moderate moderate 6.23 6.19 5.86 6.21 4.63 4.58 5.14 6.12 100.0 1.27 K417E 25.95 1.40 0.92 2.73 0.67 1.11 28 100 116 3 79 93 90
51 IgG1 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 weak weak weak strong weak moderate strong 4.48 3.87 3.79 3.72 3.46 3.94 4.92 4.72 13.5 0.716 25.80 1.39 1.22 3.64 0.61 1.02 89 99 25000 54 82 79 74
52 IgG1 2a 2.47e-10 1.57e-10 1.71e-09 6.94e-09 221.0 606.0 1080.0 >25000 >25000 >25000 134.0 471.0 739.0 64 187 >25000 >25000 6.07e+02 1.49e+03 2.52e+03 0.0 strong moderate strong strong moderate moderate moderate 6.36 6.29 6.02 6.44 5.65 5.87 5.41 6.56 95.0 1.38 Y489H 1.5mg/kg: 4210.07 24.65 1.33 1.07 3.19 0.55 0.92 18 99 134 6 82 84 75 H2
53 IgG1 6e-10 2.37e-08 189.0 801.0 1730.0 34.7 185.0 524.0 86.5 559.0 1130.0 95 242 249 800 5.91e+03 9.09e+03 1.17e+04 0.0 moderate weak weak strong weak moderate moderate 5.45 5.44 4.8 4.96 3.5 3.92 4.86 5.19 70.0 1.04 1.5mg/kg: 50.30 22.45 1.21 1.10 3.28 0.68 1.13 100 100 86.5 59 54 55 56
54 7a 8.65e-10 2.44e-09 2.44e-07 8.76e-11 1.58e-08 37.0 87.4 139.0 26.4 68.2 111.0 12.9 37.8 64.4 6 22 2 6 2.44e+02 3.44e+02 4.21e+02 weak weak weak moderate weak moderate weak 4.19 3.75 3.86 3.74 3.47 3.9 4.94 4.6 99.5 0.864 S375F|S375F,D1118H 6.90 0.37 0.47 1.40 0.58 0.97 1 3 12.9 0 39 34 96 C2
55 IgG1 1.56e-10 5.8e-11 1.15e-07 3.12e-11 1.81e-08 13.1 38.3 70.7 5.98 23.0 48.2 5.47 17.0 30.6 13 27 60 125 2.49e+02 3.85e+02 4.97e+02 0.0 strong moderate moderate strong moderate moderate strong 6.37 6.28 6.01 6.42 5.59 5.74 5.53 6.45 100.0 1.12 1.5mg/kg: 142.39 24.20 1.30 0.94 2.79 1.04 1.73 0 0 5.47 0 2 2 77 C2
56 IgG1 1.13e-10 3.82e-11 9.42e-08 1.64e-05 3e-11 1.83e-08 6.36 24.3 51.7 1.52 6.68 16.5 1.74 5.53 10.5 2 7 6 20 1.02e+02 1.77e+02 2.44e+02 0.0 strong weak moderate strong weak moderate moderate 6.33 6.23 5.96 6.34 5.41 5.27 5.34 6.32 100.0 1.86 1.5mg/kg: 50.30 26.50 1.43 1.19 3.54 0.51 0.85 0 0 1.74 0 1 1 72 C2
57 1.36e-09 2.28e-09 2.04e-07 1.53e-10 4.16e-09 10.2 26.1 45.3 1.06 3.54 7.11 3.08 9.16 17.7 1 5 3 13 5.15e+01 1.21e+02 1.99e+02 92.7 0.66 19.60 1.06 1.23 3.66 0.60 1.00 0 0 3.08 0 3 1 71 C2
58 IgG1 7a 2.98e-09 9.59e-10 1.39e-07 5.68e-11 4.6 13.6 24.7 0.805 3.1 6.51 0.45 1.74 3.19 5 16 14 27 8.74e+01 1.11e+02 1.27e+02 strong moderate weak strong weak weak weak 5.29 5.52 3.75 3.65 4.13 4.15 5.41 5.29 100.0 2.12 20.80 1.12 0.85 2.54 0.90 1.49 0 1 0.45 0 3 2 69 C2
59 7a 4.76e-10 1.2e-09 2.01e-07 7.63e-11 1.16e-08 3.7 11.8 22.5 1.24 4.07 9.24 2.75 10.4 17.7 1 1 <0.32 4 8.90e+01 1.16e+02 1.35e+02 weak weak weak weak weak moderate weak 3.98 3.75 3.8 3.73 3.46 3.9 4.83 4.7 99.4 0.957 S371F 21.00 1.11 1.64 3.28 0.99 2.91 0 2 2.75 0 1 1 72 C2
60 0.45 2 0.37 2 1.34e+01 2.07e+01 2.66e+01 0.486 20.20 1.07 1.34 2.69 0.55 1.62 0 0 0 1 2 88
61 7a 6.2e-10 1.3e-09 1.95e-07 5.25e-11 2.04e-09 4.96 15.8 30.8 0.886 4.0 10.2 2.28 8.63 18.5 2 5 <0.32 3 9.05e+01 1.32e+02 1.65e+02 weak moderate weak weak weak moderate weak 4.04 3.78 3.78 3.7 3.46 3.91 4.9 4.86 99.5 0.996 D442A 19.50 1.03 1.29 2.59 1.77 5.21 1 0 2.28 0 2 1 96 C2
62 IgG1 7a 2.04e-10 4.77e-11 6.38e-08 1.61e-05 3.55e-11 1.47e-08 8.46 34.5 74.3 4.14 14.1 27.5 7.96 26.0 49.2 4 8 4 15 1.84e+02 3.76e+02 5.71e+02 0.0 moderate strong moderate strong weak moderate moderate 6.32 6.24 5.97 6.36 5.41 5.04 5.32 6.29 100.0 1.32 1.5mg/kg: 50.63 23.45 1.24 1.54 3.09 0.67 1.96 0 0 7.96 1 0 0 87 C2
63 7a 4.52e-10 1.07e-09 1.85e-07 6.04e-11 4.26e-09 2.75 10.8 23.4 >25000 >25000 >25000 4.05 11.0 19.1 <0.32 1 <0.32 0.48 1.64e+01 3.65e+01 5.84e+01 weak moderate weak weak weak moderate weak 4.36 3.83 3.78 3.73 3.47 3.93 4.93 4.43 99.8 1.35 Y508H 20.85 1.10 1.25 2.50 0.51 1.50 0 0 4.05 1 2 1 90 C2
64 7a 7.08e-10 1.3e-09 1.69e-07 1.34e-10 1.85e-08 11.6 24.6 39.2 25.5 68.3 93.9 2.53 10.3 20.1 3 13 <0.32 4 6.20e+01 8.84e+01 1.09e+02 weak moderate weak weak weak moderate weak 3.94 3.8 3.82 3.73 3.46 3.92 4.86 4.41 96.6 1.16 del374,Y508H|del374,D571G 22.40 1.18 1.49 2.98 0.62 1.84 0 0 2.53 1 9 6 95 C3
65 IgG1 7a 1.01e-10 4.01e-11 5.1e-08 2.84e-11 1.92e-08 10.8 29.2 51.1 1.01 5.96 11.1 3.02 10.4 21.1 16 26 18 36 2.50e+02 4.05e+02 5.37e+02 moderate weak moderate strong weak moderate moderate 6.32 6.27 5.97 6.42 5.65 5.77 5.61 6.48 100.0 1.72 K417E 21.40 1.13 1.45 2.90 0.68 1.99 0 0 3.02 0 6 6 96 C3
66 5.89e-10 1.14e-09 1.4e-07 1.29e-10 1.88e-08 4.17 11.0 19.5 4.47 15.2 31.9 8.61 26.7 49.6 1 3 <0.32 4 1.12e+02 3.10e+02 5.62e+02 weak weak weak strong weak moderate strong 4.28 4.07 3.88 3.85 3.47 3.9 4.94 4.75 100.0 1.18 21.75 1.15 1.65 3.30 0.71 2.10 0 0 8.61 0 4 8 73 C3
67 IgG1 2a 1.39e-09 6.13e-10 2.85e-07 1.81e-10 7.33e-08 17500.0 >25000 >25000 >25000 >25000 >25000 21.7 419.0 1160.0 3404 12080 1.99e+03 3.49e+03 4.85e+03 0.0 strong weak moderate strong weak moderate moderate 6.19 6.13 5.77 6.15 4.77 4.67 5.22 6.22 100.0 1.33 0.5mg/kg: 152.54|1.5mg/kg: 665.62 23.10 1.22 1.30 2.60 0.56 1.65 62 70 21.7 29 78 92 83
68 IgG1 2d 4.3e-11 3.61e-11 2.89e-09 2.82e-07 2.05e-09 2.36e-09 9.83 25.8 43.8 >25000 >25000 >25000 10.3 30.1 54.8 1 1 >25000 >25000 5.93e+01 8.74e+01 1.10e+02 None strong strong strong strong moderate moderate strong 6.39 6.33 6.03 6.46 5.73 6.14 5.91 6.59 100.0 1.47 0.5mg/kg: 736.35 40.55 2.14 2.33 4.65 1.39 4.07 0 98 10.3 0 88 90 91 H2
69 IgG1 1 1.36e-09 2.2e-10 2.67e-08 7.05e-11 8.92e-10 6840.0 20200.0 >25000 262.0 >25000 >25000 558.0 1730.0 2320.0 482 2470 2.50e+04 2.50e+04 2.50e+04 0.0 strong moderate moderate moderate weak moderate strong 6.32 6.26 5.99 6.41 5.61 5.88 5.28 6.56 74.1 2.52 1.5mg/kg: 501.00 33.90 1.79 1.05 2.11 1.07 3.16
70 2.62e-09 3.79e-09 1.3e-07 6.34e-09 606.0 3820.0 9900.0 >25000 >25000 >25000 >25000 >25000 >25000 4929 19977 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 weak weak weak moderate weak weak weak 4.21 3.9 3.89 3.75 3.48 3.93 5.0 4.72 86.9 1.11 24.75 1.31 1.30 2.61 0.55 1.62
71 2.51e-09 1.27e-09 1.29e-07 5.91e-10 876.0 5810.0 18200.0 >25000 >25000 >25000 >25000 >25000 >25000 18221 >25000 >12500 >12500 2.50e+04 2.50e+04 2.50e+04 weak weak moderate moderate weak moderate moderate 4.2 3.87 3.85 5.34 3.47 3.92 5.02 4.72 90.1 1.26 23.55 1.24 1.45 2.90 0.66 1.94
72 2.8e-09 3.72e-09 3.14e-08 5.65e-09 137.0 536.0 1110.0 >25000 >25000 >25000 189.0 913.0 2190.0 362 898 >12500 >12500 5.20e+02 1.01e+03 1.48e+03 weak moderate moderate weak weak moderate moderate 4.16 3.81 3.82 3.72 3.48 3.91 4.81 4.43 98.8 0.639
73 2a 2.85e-09 4.54e-09 2.49e-08 6.99e-09 302.0 1460.0 3270.0 >25000 >25000 >25000 >25000 >25000 >25000 364 1119 >12500 >12500 3.13e+03 5.68e+03 8.04e+03 weak weak weak weak weak moderate moderate 4.21 4.07 3.87 3.72 3.47 3.95 4.95 4.63 100.0 1.45 37.85 2.00 2.06 4.11 1.43 4.21 66 100 25000 36 95 95 100
74 IgG1 3a 5.52e-10 2.73e-10 3.42e-08 1.44e-10 5.56e-08 78.2 2600.0 9560.0 >25000 >25000 >25000 >25000 >25000 >25000 78 543 44 220 1.55e+03 3.63e+03 5.96e+03 0.0 strong strong moderate weak weak moderate strong 6.22 6.18 5.9 6.27 5.25 4.99 5.28 6.37 96.2 1.7 0.5mg/kg: 511.23|1.5mg/kg: 1286.76 34.55 1.82 1.65 3.30 1.82 5.37 40 68 25000 24 96 98 89
75 IgG1 3a 2.49e-09 1.18e-09 1.27e-07 3.92e-10 8.85e-08 9650.0 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 379 3034 689 3668 2.50e+04 2.50e+04 2.50e+04 moderate strong moderate weak weak moderate moderate 6.13 6.1 5.8 6.2 5.09 4.88 5.15 6.25 91.3 1.68 35.65 1.88 2.00 4.00 1.45 4.25 63 93 25000 64 94 96 94
76 IgG1 3a 3.62e-09 1.46e-09 1.77e-07 9.63e-10 5.26e-08 17600.0 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 3548 11060 2214 10897 2.50e+04 2.50e+04 moderate moderate moderate weak weak moderate weak 5.99 6.03 5.71 6.08 4.5 4.42 5.13 6.11 92.6 2.7 20.25 1.07 1.70 3.40 0.81 2.40 67 91 25000 60 93 95 80
77 IgG1 3a 4.34e-09 1.79e-09 3.86e-07 1.07e-09 24600.0 >25000 >25000 >25000 >25000 >25000 833.0 1010.0 1070.0 2.50e+04 2.50e+04 2.50e+04 moderate weak moderate strong weak moderate moderate 5.83 5.82 5.25 5.54 3.5 3.94 4.89 5.53 78.3 1.31 21.05 1.11 2.21 4.42 0.87 2.56 81 100 833 79 91 93 90
78 IgG1 5a 7.18e-10 1.87e-10 3.93e-07 1.35e-10 74.2 224.0 663.0 44.9 164.0 519.0 >25000 >25000 >25000 12 44 10 33 4.61e+01 8.75e+02 4.90e+03 100.0 strong weak moderate strong weak moderate moderate 6.23 6.21 5.91 6.32 5.5 5.57 5.57 6.44 48.7 2.42 del68-69,V70I 0.5mg/kg: 285.14|1.5mg/kg: 1432.71 38.55 2.03 1.95 3.90 1.49 4.37 17 38 25000 18 89 96 88 F
79 IgG1 2a 8.78e-11 6.21e-11 7.45e-10 2.89e-07 3.51e-10 1.01e-08 53.7 140.0 235.0 315.0 >25000 >25000 39.1 80.6 129.0 0.38 3 379 747 2.38e+01 1.76e+02 5.68e+02 10.0 strong strong strong strong moderate moderate moderate 6.36 6.3 6.02 6.43 5.64 5.9 5.43 6.55 99.1 2.93 1.5mg/kg: 8009.08 31.95 1.69 1.73 3.45 2.31 6.78 1 34 39.1 1 32 38 37 H1
80 IgG1 3a 2.18e-09 1.21e-09 1.04e-07 5.09e-10 792.0 3340.0 7600.0 371.0 3670.0 >25000 232.0 1270.0 >25000 222 1595 978 3872 3.58e+03 8.52e+03 1.42e+04 0.0 strong moderate moderate strong weak moderate moderate 6.17 6.18 5.88 6.27 5.45 5.36 5.37 6.37 93.7 1.98 1.5mg/kg: 2316.58 31.85 1.68 1.46 2.91 1.27 3.75 52 64 232 27 81 81 76
81 IgG1 3a 1.47e-09 8.4e-10 9.88e-08 1.52e-10 7.16e-08 824.0 4140.0 9950.0 1390.0 >25000 >25000 227.0 >25000 >25000 100 627 268 736 4.31e+03 1.24e+04 2.30e+04 0.0 strong moderate moderate moderate weak moderate weak 6.19 6.13 5.85 6.24 5.28 5.16 5.26 6.3 86.8 3.09 0.5mg/kg: 397.89|1.5mg/kg: 1106.86 24.85 1.31 2.05 4.10 0.60 1.78 54 75 227 39 93 83 73 B
82 IgG1 7b 1.28e-09 1.9e-09 3.61e-08 1.02e-09 3.29e-08 >25000 >25000 >25000 >25000 >25000 >25000 1950.0 3020.0 3360.0 20205 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 0.0 strong weak weak weak weak moderate moderate 6.04 6.01 5.61 5.94 4.02 4.12 5.03 5.8 33.1 3.82 1.5mg/kg: 1030.22 27.35 1.44 1.12 2.24 1.23 3.60 87 100 1950 83 96 81 77
83 7a 3.73e-10 2.14e-10 8.94e-08 6.75e-11 4.35e-08 1030.0 3200.0 6030.0 335.0 1140.0 1700.0 380.0 >25000 >25000 99 396 172 503 2.50e+03 2.90e+03 3.16e+03 10.0 strong weak moderate moderate weak moderate moderate 6.3 6.22 5.94 6.28 5.04 5.1 5.29 6.26 98.0 3.84 0.5mg/kg: 1033.55|1.5mg/kg: 9035.08 43.85 2.31 1.82 3.65 1.62 4.76 44 36 380 8 100 90 77 B
84 7a 4.33e-10 2.78e-10 9.29e-08 6.99e-11 1.62e-08 1570.0 4380.0 7700.0 374.0 1440.0 2000.0 569.0 2190.0 5470.0 49 175 225 573 1.27e+03 2.07e+03 2.75e+03 0.0 strong weak moderate weak weak moderate moderate 6.31 6.23 5.95 6.32 5.04 5.12 5.31 6.31 96.2 1.36 E654A|R408G 1.5mg/kg: 9120.49 25.15 1.33 0.93 1.85 2.26 6.65 53 46 569 10 100 92 87 A
85 IgG1 3a 2.59e-09 8.04e-10 1.51e-07 2.71e-10 1.25e-07 >25000 >25000 >25000 >25000 >25000 >25000 284 786 429 1762 9.62e+03 3.59e+04 7.77e+04 strong moderate moderate weak weak moderate moderate 6.07 6.09 5.73 6.12 4.79 4.63 5.28 6.06 93.2 3.81 44.55 2.35 1.95 3.90 1.45 4.26 57 96 25000 58 100 100 100 A
86 IgG1 2.16e-09 4.41e-10 1.03e-07 3.15e-10 1.03e-07 6150.0 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 691 4356 1.68e+04 4.58e+04 8.24e+04 moderate moderate moderate weak weak moderate moderate 6.21 6.18 5.92 6.3 5.38 5.42 5.32 6.39 96.8 2.05 36.45 1.92 2.13 4.26 1.18 3.46 65 94 25000 62 90 100 96 A
87 IgG4 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 weak moderate weak weak weak moderate weak 4.0 3.79 3.62 3.71 3.46 3.9 4.91 4.65 8.2 1.22 30.20 1.59 1.80 3.60 1.15 3.38
88 IgG1
89 IgG1 1 1.22e-09 5.64e-10 6.73e-08 1.49e-10 2.81e-09 536.0 2130.0 4470.0 412.0 1450.0 2380.0 82.5 406.0 >25000 417 1117 4.46e+03 2.17e+04 5.46e+04 0.0 weak moderate weak weak weak moderate moderate 6.07 6.24 5.73 5.62 5.42 3.93 4.13 5.21 60.9 1.44 1.5mg/kg: 114.40 31.75 1.68 1.60 3.20 1.72 5.06 nt nt nt nt nt nt nt
90 IgG1 2c 2.93e-10 1.27e-10 1.1e-07 1.86e-09 380.0 1190.0 2110.0 1040.0 1520.0 1670.0 >25000 >25000 >25000 218 1357 1.89e+03 4.31e+03 6.98e+03 moderate weak moderate strong weak moderate moderate 6.33 6.26 5.97 6.38 5.53 5.74 5.59 6.49 100.0 1.57 26.25 1.39 1.67 3.34 0.80 2.35 32 100 25000 68 100 100 100 H3
91 IgG1 4c 2.43e-10 5.69e-10 4.69e-09 4.46e-06 6.46e-10 3.48e-09 327.0 1660.0 4940.0 814.0 1220.0 1350.0 >25000 >25000 >25000 66 680 4846 10146 2.50e+04 2.50e+04 2.50e+04 None strong weak strong strong moderate moderate moderate 6.26 6.23 5.91 6.34 5.48 5.57 5.53 6.39 21.7 3.92 0.5mg/kg: 1375.38 49.40 2.61 1.06 2.13 1.41 4.13 61 100 25000 80 76 90 90 G
92 IgG1 2c 1.04e-09 5.73e-10 1.96e-07 208.0 521.0 918.0 >25000 >25000 >25000 >25000 >25000 >25000 144 368 5.92e+02 1.03e+03 1.43e+03 strong moderate moderate moderate weak moderate moderate 6.12 6.08 5.8 6.18 3.8 5.13 5.23 6.17 91.2 1.49 51.95 2.74 1.33 2.66 1.75 5.15 26 100 25000 78 97 100 100
93 IgG2 1 1.02e-10 2.7e-11 4.31e-10 6.52e-07 2.02e-11 5.53e-10 69.3 225.0 407.0 26.9 89.8 199.0 26.2 70.1 138.0 >25000 >25000 7.05e+01 9.92e+01 1.21e+02 0.0 moderate weak strong strong weak moderate moderate 6.37 6.32 5.99 3.8 5.77 4.36 4.73 4.56 95.4 1.43 R685S 0.5mg/kg: 66.10|1.5mg/kg: 295.85 24.60 1.30 1.50 3.00 0.62 1.82 3 4 26.2 1 2 2 1 B
94 IgG1 4a 1.04e-10 1.1e-10 5.62e-09 4.35e-11 2.77e-11 35.2 96.8 167.0 16.2 42.7 73.1 >25000 >25000 >25000 4 8 2 6 8.87e+01 1.38e+02 1.79e+02 90.0 moderate moderate weak weak weak weak weak 6.18 6.19 5.84 6.08 4.29 4.6 5.42 6.02 98.0 1.64 0.5mg/kg: 2121.07|1.5mg/kg: 7219.93 34.20 1.80 1.60 3.20 1.05 3.10 1 11 25000 81 0 1 1 H1
95 IgG1 4a 8.41e-11 4.88e-11 2.75e-08 2.51e-10 3.28e-10 21.2 63.8 122.0 >25000 >25000 >25000 24.2 6.69 3.65 0.34 1 798 14 1.24e+02 3.45e+02 6.26e+02 None strong moderate weak weak weak moderate moderate 6.18 6.12 5.69 6.07 4.3 4.49 5.02 6.15 98.8 1.93 0.5mg/kg: 2508.19 24.90 1.31 1.35 2.70 0.52 1.53 10 99 24.2 96 5 7 13 G
96 IgG1 5a 7.65e-11 5.66e-11 9.22e-08 4.7e-11 21.3 59.4 112.0 15.5 78.9 191.0 27.7 114.0 267.0 <0.32 6 0.51 11 5.77e+01 1.76e+02 3.38e+02 None moderate weak weak moderate weak moderate strong 6.02 6.18 5.41 6.01 4.99 4.16 5.09 6.24 44.8 1.26 G339C 0.5mg/kg: 1912.34 3 25 27.7 10 100 100 94 F
97 IgG1 1 1.31e-11 6.31e-12 4.96e-09 3.41e-06 1.31e-11 6.2e-09 6.35 19.1 33.5 6.8 32.1 75.1 3.02 9.83 17.7 <0.32 1 <0.32 6 8.25e+01 1.41e+02 1.93e+02 30.0 100.0 1.4 0.5mg/kg: 5702.68 0 5 3.02 0 85 97 93 H2
98 IgG1 1 7.35e-11 6.51e-11 3.82e-09 4.23e-11 2.66e-09 130.0 416.0 764.0 26.9 131.0 378.0 50.1 169.0 330.0 18 66 2 14 2.89e+02 4.28e+02 5.38e+02 10.0 strong moderate weak strong weak strong moderate 6.07 6.06 5.37 6.06 4.32 4.17 5.07 6.11 98.5 1.67 0.5mg/kg: 1495.80|1.5mg/kg: 4438.01 0 3 50.1 0 65 78 80 B
99 IgG1 2c 4.03e-11 2.13e-11 2.47e-09 1.42e-06 1.37e-08 13.8 35.8 60.1 >25000 >25000 >25000 >25000 >25000 >25000 <0.32 <0.32 1605 3436 8.36e+01 1.51e+02 2.14e+02 10.0 strong moderate moderate moderate weak moderate moderate 6.28 6.16 5.95 6.13 4.96 5.37 5.33 6.22 100.0 1.55 0.5mg/kg: 2091.21|1.5mg/kg: 7010.57 1 96 25000 8 100 96 82 H3
100 IgG1 2b 1.45e-11 8.37e-12 3.3e-09 1.61e-06 1.44e-11 3.66e-09 7.45 18.1 29.7 14.0 65.6 165.0 2.87 10.4 21.8 1 3 9 29 1.82e+01 2.93e+01 3.87e+01 80.0 strong strong moderate moderate weak moderate strong 6.28 6.13 6.05 6.19 5.07 5.56 5.21 6.27 100.0 2.19 0.5mg/kg: 3457.40|1.5mg/kg: 12740.40 0 5 2.87 0 54 73 69 H2
101 IgG1 4b 2.99e-11 2.26e-11 3.94e-09 2.7e-11 6.43e-11 11.3 27.7 45.2 6.3 20.1 36.8 8.52 45.0 96.2 6 21 9 22 9.78e+01 2.27e+02 3.72e+02 90.0 strong moderate weak moderate weak strong strong 6.26 6.19 6.02 6.11 5.09 5.68 5.58 6.27 100.0 2.7 S494L 0.5mg/kg: 2611.60|1.5mg/kg: 10051.28 0 0 8.52 2 51 99 1 G
102 2b 1.43e-10 6.77e-11 1.45e-09 4.98e-07 3.59e-11 5.78 15.8 27.0 4.47 10.6 17.1 2.81 7.3 10.2 <0.32 <0.32 <0.32 <0.32 2.16e+00 1.06e+01 2.67e+01 0.0 weak weak weak weak weak weak weak 3.84 3.91 3.64 3.33 4.22 3.8 4.63 4.25 84.3 1.3 0.5mg/kg: 50.30|1.5mg/kg: 50.30 19.05 1.07 1.21 1.13 0.49 1.88
103 2b 8.34e-11 1.22e-10 1.62e-09 4.77e-07 5.37e-11 3.25e-10 8.82 24.4 42.6 >25000 >25000 20.0 >25000 13.6 26.1 <0.32 <0.32 <0.32 <0.32 2.17e+01 4.28e+01 6.38e+01 weak weak weak weak weak weak weak 3.83 3.71 3.62 3.36 4.17 3.76 4.69 4.27 84.9 1.21 24.45 1.37 1.12 1.05 0.48 1.85
104 2b 9.36e-11 8.39e-11 1.37e-09 6.74e-11 5.15e-10 16.8 26.2 33.8 60.2 204.0 444.0 264.0 631.0 1060.0 <0.32 <0.32 3 7 4.42e+00 6.57e+00 8.28e+00 weak weak weak weak moderate weak weak 3.8 3.74 3.63 3.33 4.22 3.78 4.78 4.24 86.1 1.22 23.20 1.30 1.56 1.46 0.36 1.38
105 IgG1 2d 2.15e-11 1.26e-11 1.62e-08 5.44e-10 335.0 876.0 1520.0 >25000 >25000 >25000 >25000 >25000 >25000 23 68 >25000 >25000 1.86e+02 1.95e+02 2.00e+02 moderate moderate moderate moderate weak moderate weak 6.27 6.19 6.01 6.14 4.36 5.63 5.38 6.25 100.0 1.45 Q493H,R685S 16.35 0.92 1.37 1.28 0.24 0.94 15 99 25000 86 93 97 94 H3
106 IgG1 2d 1.3e-11 6.62e-12 9.24e-10 2.79e-07 3.66e-10 6.85 18.4 31.3 >25000 >25000 >25000 >25000 >25000 >25000 <0.32 2 864 2686 1.34e+00 2.12e+00 2.78e+00 None moderate strong moderate weak weak weak weak 6.3 6.14 5.99 6.19 4.82 5.55 5.42 6.25 100.0 1.66 S494L 0.5mg/kg: 4633.30 0 100 25000 80 85 94 94 H3
107 IgG1 2d 2.23e-11 1e-11 9.39e-10 2.26e-07 3.61e-10 1.56e-07 8.2 28.9 54.0 >25000 >25000 >25000 >25000 >25000 >25000 <0.32 1 302 889 2.02e+01 2.78e+01 3.36e+01 None strong strong moderate moderate weak moderate moderate 6.31 6.22 6.07 6.18 5.19 5.62 5.41 6.27 100.0 2.09 E406D,S494P 0.5mg/kg: 3584.13 38.45 2.15 1.20 1.12 0.56 2.15 0 100 25000 80 90 100 96 H3
108 IgG1 2d 2.28e-11 1.09e-11 1.04e-09 3.6e-07 4.66e-10 1.15e-07 12.3 35.1 62.6 >25000 >25000 >25000 >25000 >25000 >25000 2 5 4915 25000 2.55e+01 4.70e+01 6.73e+01 None strong strong moderate strong weak moderate moderate 6.3 6.18 6.02 6.22 5.08 5.66 5.28 6.26 100.0 1.61 R685S 0.5mg/kg: 3066.01 18.80 1.05 1.56 1.46 0.34 1.29 97 100 25000 91 99 100 100 H3
109 IgG1 2d 1.63e-11 1.06e-11 5.8e-10 1.96e-07 3.86e-10 3.59e-08 14.5 32.5 51.4 >25000 >25000 >25000 >25000 >25000 >25000 1 1 5666 18558 1.88e+01 2.58e+01 3.10e+01 strong strong moderate strong weak moderate strong 6.27 6.16 5.99 6.1 4.65 5.41 5.22 6.25 100.0 1.65 24.20 1.36 1.23 1.15 0.66 2.52 95 96 25000 100 100 100 90 H3
110 IgG1 2d 2.26e-11 7.08e-12 1.53e-09 7.53e-07 6.18e-10 1.4e-07 18.0 49.5 88.6 >25000 >25000 >25000 2000.0 2040.0 2050.0 2 6 19149 >25000 1.91e+01 3.97e+01 6.10e+01 strong moderate moderate strong weak strong strong 6.3 6.23 6.09 6.18 5.06 5.58 5.3 6.28 100.0 1.9 48.90 2.74 1.32 1.24 1.15 4.42 1 93 2000 79 97 89 87 H3
111 IgG1 2d 2.02e-11 1.01e-11 1.39e-09 3.84e-07 3.94e-10 5.42e-08 17.3 44.0 74.2 >25000 >25000 >25000 >25000 >25000 >25000 15 31 16200 >25000 6.71e+01 8.75e+01 1.02e+02 None strong moderate moderate strong weak strong strong 6.29 6.2 6.07 6.19 5.01 5.6 5.5 6.29 100.0 1.77 0.5mg/kg: 3120.30 33.10 1.85 1.32 1.24 0.66 2.52 0 85 25000 80 92 90 82 H3
112 IgG1 2d 1.78e-11 9.16e-12 3.46e-10 1.23e-07 3.09e-10 4.14e-08 10.1 26.4 44.2 >25000 >25000 >25000 0.976 >25000 >25000 3 14 8465 23584 2.53e+01 3.77e+01 4.76e+01 None moderate strong moderate strong weak strong strong 6.25 6.18 6.01 6.12 4.88 5.5 5.38 6.27 100.0 1.85 S494P|S494L 0.5mg/kg: 1062.27 46.45 2.60 1.14 1.06 1.28 4.92 0 85 0.976 44 89 90 73 H3
113 IgG1 7c 3.71e-10 2.5e-10 1.37e-09 1.48e-10 2.79e-09 9750.0 >25000 >25000 2140.0 5390.0 8490.0 3580.0 9210.0 11700.0 1846 6065 2.50e+04 2.50e+04 2.50e+04 moderate moderate weak strong weak moderate moderate 6.06 6.11 5.48 6.03 4.35 4.54 4.12 6.09 27.2 1.41 38.90 2.18 0.98 0.92 0.96 3.71 85 88 3580 83 85 92 87 C3
114 IgG1 7c 3.53e-10 2.21e-10 6.2e-10 7.49e-08 1.25e-10 2.08e-09 2660.0 8580.0 15700.0 1290.0 5380.0 7560.0 >25000 >25000 >25000 120 1435 2.50e+04 2.50e+04 2.50e+04 moderate moderate moderate moderate weak moderate moderate 6.0 6.01 5.28 5.98 4.26 4.28 4.85 6.05 31.1 1.96 16.15 0.90 1.30 1.21 0.40 1.52 78 81 25000 64 84 90 81 C3
115 IgG1 7c 3.79e-10 2.43e-10 8.54e-10 3.57e-07 2.19e-10 2.99e-09 3410.0 11600.0 21200.0 >25000 >25000 >25000 >25000 >25000 >25000 965 2939 1.32e+04 2.78e+04 4.30e+04 moderate moderate moderate strong weak moderate moderate 6.05 6.06 5.27 6.0 4.28 4.45 4.83 6.07 34.5 1.54 37.70 2.11 1.04 0.97 0.56 2.13 85 89 25000 76 89 90 81 C3
116 IgG1 5a 9.11e-11 5.41e-11 1.03e-08 3.47e-11 2.55e-08 9.43 27.0 47.4 8.93 27.9 45.6 8.91 19.9 29.9 2 5 <0.32 <0.32 5.26e+01 7.77e+01 9.76e+01 90.0 moderate moderate strong strong weak weak moderate 6.03 5.87 5.47 5.9 4.25 4.37 4.92 6.03 29.2 2.1 G339V|G339C|G339F 0.5mg/kg: 667.65|1.5mg/kg: 2646.21 15.55 0.87 1.24 1.16 0.25 0.96 0 0 8.91 0 84 92 84 F
117 IgG1 4b 1.29e-11 6.38e-12 9.06e-10 2.88e-07 3.53e-11 1.31e-11 7.32 16.9 27.3 561.0 2520.0 6210.0 7030.0 >25000 >25000 2 7 0.5 16 1.29e+01 1.51e+01 1.66e+01 80.0 moderate weak moderate weak moderate strong moderate 6.35 6.21 6.23 6.14 6.48 6.06 5.66 6.33 64.6 1.58 0.5mg/kg: 4081.89|1.5mg/kg: 9977.60 38.50 2.16 2.92 2.73 1.55 5.98 1 17 7030 42 1 72 1 G
118 IgG1 173.0 415.0 710.0 >25000 >25000 >25000 102.0 622.0 1190.0 63 173 542 1823 2.24e+02 3.87e+02 5.32e+02 60.0 moderate strong moderate weak weak moderate moderate 6.31 6.12 6.15 6.18 5.28 5.88 5.8 6.32 100.0 2.33 S371F 0.5mg/kg: 1151.12|5mg/kg: 14018.21 38.95 2.18 0.90 0.84 1.10 4.23
119 7a 1.16e-09 4.52e-10 1.79e-07 5.71e-11 2.69 8.7 16.5 0.907 3.5 8.08 2.03 6.23 12.7 <0.32 3 <0.32 4 1.71e+01 2.28e+01 2.70e+01 weak weak weak weak moderate weak weak 3.89 3.69 3.65 3.57 3.82 3.93 5.44 4.39 100.0 1.2 18.60 1.04 2.08 1.94 0.45 1.73 0 0 2.03 1 1 0 87 C2
120
121 7a 1.06e-09 4.29e-10 1.95e-07 3.75e-11 2.2 8.02 16.1 0.637 2.13 3.93 0.431 2.34 5.71 <0.32 <0.32 0.64 2 1.79e+01 3.82e+01 5.96e+01 weak weak weak strong weak weak weak 3.87 3.67 3.68 3.58 3.81 3.95 4.81 4.38 99.5 1.16 21.75 1.22 1.67 1.56 0.73 2.81 0 0 0.431 0 1 1 95 C2
122 7a 9.01e-10 6.01e-10 2.03e-07 4.09e-11 2.1 7.32 14.4 1.31 5.67 12.6 1.09 3.74 7.89 2 8 <0.32 3 3.98e+01 1.44e+02 3.06e+02 weak weak weak weak weak weak weak 3.84 3.7 3.67 3.61 3.81 3.95 4.85 4.36 97.9 0.684 21.90 1.23 1.20 1.12 2.00 7.71 0 0 1.09 0 1 1 85 C2
123 7a 1.33e-09 4.06e-10 2.06e-07 3.68e-11 1.08 3.17 5.97 0.51 1.74 3.55 0.179 0.731 1.46 <0.32 <0.32 <0.32 0.96 1.82e+01 1.17e+02 3.49e+02 0.0 weak weak weak weak weak moderate weak 3.88 3.71 3.67 3.58 3.84 3.94 5.14 4.37 97.6 2.03 1.5mg/kg: 50.30 22.70 1.27 1.49 1.39 0.44 1.69 0 0 0.179 0 1 1 78 C2
124 7a 9.46e-10 5.39e-10 1.67e-07 3.76e-11 0.893 2.82 5.31 0.678 2.69 5.87 0.631 2.14 4.16 <0.32 0.92 <0.16 <0.16 1.82e+01 3.46e+01 5.02e+01 0.0 weak weak weak weak weak weak weak 3.88 3.7 3.69 3.57 3.81 3.93 5.59 4.39 98.3 1.36 0.5mg/kg: 50.30|1.5mg/kg: 50.30 19.80 1.11 1.73 1.61 0.34 1.31 0 0 0.631 2 1 1 82 C2
125 7a 1.6e-09 4.99e-10 1.84e-07 6.42e-11 2.02 6.44 12.1 1.93 4.88 8.89 1.76 6.76 14.2 1 1 <0.32 5 4.12e+01 4.52e+01 4.77e+01 weak weak weak strong weak moderate weak 3.86 3.68 3.65 3.56 3.83 3.94 5.52 4.42 98.8 1.14 24.90 1.39 1.56 1.46 0.88 3.37 0 0 1.76 0 1 0 75 C2
126 7a 9.42e-10 3.95e-10 1.39e-07 6.06e-11 2.02 6.34 11.9 1.92 7.37 15.4 0.245 7.11 23.0 0.35 1 <0.32 0.84 1.97e+01 6.74e+01 1.39e+02 weak weak weak moderate weak weak weak 3.85 3.69 3.65 3.56 3.81 3.94 5.44 4.46 98.5 2.58 19.80 1.11 1.90 1.78 0.50 1.92 0 0 0.245 0 0 0 88 C2
127 IgG1 7a 1.81e-09 9.03e-10 1.06e-07 5.01e-11 2.77 10.8 23.0 >25000 >25000 >25000 1.92 7.64 16.7 1 2 0.34 3 4.04e+01 4.60e+01 4.97e+01 0.0 strong moderate weak moderate moderate strong moderate 5.96 5.95 5.57 5.96 5.64 4.28 5.77 5.88 98.6 2.68 0.5mg/kg: 50.30|1.5mg/kg: 50.30 29.75 1.67 1.65 1.54 0.94 3.63 0 0 1.92 0 1 1 79 C2
128 IgG1 7a 3.6e-09 1.37e-09 1.19e-07 7.74e-11 5.58 18.3 34.4 2.66 11.2 22.8 2.84 9.37 19.3 7.40e+01 1.09e+02 1.37e+02 0.0 strong moderate weak weak weak strong moderate 6.17 6.1 5.71 6.11 5.95 5.11 5.05 6.12 98.6 2.82 0.5mg/kg: 50.30|1.5mg/kg: 50.30 28.75 1.61 1.10 1.03 1.34 5.15 1 0 2.84 0 6 9 72 C3
129 7a 1.25e-09 6.49e-10 1.35e-07 5.38e-11 1.98 7.46 15.9 1.59 5.95 12.3 0.936 2.98 4.85 <0.32 1 8 17 3.36e+01 7.58e+01 1.22e+02 0.0 weak weak weak moderate weak weak weak 3.86 3.7 3.67 3.66 3.82 3.93 5.8 4.36 99.6 1.63 0.5mg/kg: 50.30|1.5mg/kg: 50.30 17.65 0.99 1.75 1.64 0.85 3.27 1 0 0.936 0 1 1 66 C2
130 <0.32 <0.32 <0.16 <0.16
131 IgG 7c 1.01e-09 3.78e-10 2.05e-09 9.09e-07 3.97e-10 8.82e-09 13600.0 >25000 >25000 >25000 >25000 >25000 6560.0 11100.0 12700.0 1550 9937 2.50e+04 2.50e+04 2.50e+04 moderate moderate weak weak weak strong weak 6.15 6.09 5.66 6.01 3.82 3.94 4.85 6.17 14.6 2.1 47.60 2.67 0.90 0.84 0.92 3.52 75 90 6560 56 97 93 84 C3
132 IgG 9.83e-10 5.63e-10 2.18e-10 1.02e-09 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 0.0 moderate moderate moderate moderate moderate weak weak 5.84 5.85 5.25 5.67 3.83 3.93 4.82 5.87 2.5 1.67 1.5mg/kg: 8370.07 14.85 0.83 1.95 1.82 0.92 3.54 89 89 25000 70 100 98 91 E3
133 IgG 7.08e-10 1.23e-09 3.12e-08 1.12e-09 1.07e-08 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 moderate moderate strong strong weak weak moderate 6.21 6.19 5.91 6.18 3.86 3.93 4.81 6.24 5.5 2.25 8.84 0.50 47 96 25000 52 96 96 90 E3
134 IgG 5a 6.75e-10 3.5e-10 9e-08 3.66e-11 4.15e-09 48.2 161.0 317.0 22.9 79.8 162.0 21.4 61.7 110.0 16 48 11 69 1.90e+02 2.07e+02 2.18e+02 70.0 strong strong moderate strong weak moderate moderate 6.11 6.04 5.79 6.06 5.76 5.01 4.73 6.12 63.5 2.08 0.5mg/kg: 510.44|1.5mg/kg: 1800.11 32.80 1.84 1.07 1.00 0.69 2.63 3 8 21.4 3 72 97 82 G
135 IgG >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 None weak weak moderate strong weak weak weak 3.84 3.69 3.71 3.58 3.83 3.95 4.68 4.29 6.5 1.44 0.5mg/kg: 50.30 17.45 0.98 4.39 4.10 0.48 1.87 33 85 25000 22 54 81 79
136 IgG 2a 6.68e-10 3.33e-10 9.86e-09 3.44e-06 6.13e-09 77.7 231.0 427.0 >25000 >25000 >25000 20.4 161.0 368.0 36 81 >25000 >25000 3.31e+02 6.01e+02 8.51e+02 10.0 strong moderate moderate strong weak moderate moderate 6.24 6.24 5.95 6.19 5.62 5.61 4.88 6.32 99.5 3.41 0.5mg/kg: 1172.77|1.5mg/kg: 3502.69 34.30 1.92 0.52 0.49 0.55 2.12 7 92 20.4 4 63 90 80 H2
137 IgG 1.84e-09 1.59e-09 1.15e-09 1.06e-09 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 0.0 moderate weak moderate moderate weak weak weak 6.08 6.07 5.72 6.02 3.81 3.93 4.74 6.11 1.77 1.5mg/kg: 50.30 26.45 1.48 1.91 1.78 0.67 2.58 61 91 25000 46 72 82 77 E3
138 IgG 5.28e-07 8.44e-10 3.74e-08 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 moderate weak moderate strong weak weak weak 5.85 5.82 5.48 5.49 3.82 3.94 4.64 5.61 2.6 25.00 1.40 1.12 1.05 0.52 2.00 75 93 25000 44 73 91 65 E3
139 IgG 7b 6.64e-10 2.12e-09 4.46e-08 2.17e-10 6.04e-08 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 0.0 moderate weak moderate moderate weak weak weak 6.14 6.2 5.73 6.13 3.84 3.94 4.69 6.15 63.9 1.59 1.5mg/kg: 2508.65 80 90 25000 67 66 100 71 C3
140 IgG 2d 1.35e-10 7.66e-11 1.9e-07 181.0 621.0 1310.0 >25000 >25000 >25000 159.0 881.0 1740.0 14 87 >25000 >25000 2.09e+03 7.80e+03 1.69e+04 70.0 strong moderate moderate strong weak strong strong 6.08 6.1 5.71 5.99 5.35 5.37 4.75 6.06 100.0 2.48 1.5mg/kg: 1045.49 36.45 2.04 0.97 0.91 0.80 3.08 23 95 159 23 80 93 65 H3
141 IgG 2c 2.53e-10 1.3e-10 1.07e-07 2470.0 9640.0 19800.0 >25000 >25000 >25000 >25000 >25000 >25000 107 281 1.43e+03 2.43e+03 3.31e+03 10.0 moderate moderate moderate strong weak strong strong 6.22 6.2 5.96 6.25 5.29 5.44 5.04 6.33 100.0 3.44 1.5mg/kg: 8654.62 45.20 2.53 1.34 1.26 1.25 4.83 26 95 25000 42 56 89 68 H3
142 IgG 2a 2.92e-10 2.8e-10 1.65e-08 6.08e-10 8.16e-09 87.4 286.0 534.0 782.0 11300.0 >25000 40.2 114.0 209.0 16 74 >25000 >25000 3.06e+02 5.50e+02 7.76e+02 strong moderate moderate strong weak moderate moderate 6.19 6.19 5.85 6.16 5.3 5.5 4.93 6.28 100.0 4.23 0.5mg/kg: 1642.16 44.80 2.51 2.10 1.96 2.56 9.83 8 99 40.2 1 60 57 64 H2
143 IgG 1 3.82e-10 2.34e-10 5.91e-09 237.0 733.0 1660.0 426.0 1680.0 2380.0 39.8 136.0 258.0 8 36 >25000 >25000 7.92e+02 9.10e+02 9.87e+02 0.0 strong moderate weak moderate weak moderate moderate 6.17 6.2 5.91 6.14 5.67 5.33 5.04 6.37 100.0 2.42 0.5mg/kg: 6260.70 27.60 1.28 0.49 1.46 0.81 1.36 20 98 39.8 4 90 87 94 B
144 IgG1 5a 2.45e-10 1.09e-10 1.03e-10 3.21e-07 1.21e-10 2.86e-10 4.39 10.6 17.5 26.8 112.0 207.0 24.3 70.3 127.0 5 32 12 74 1.60e+02 2.54e+02 3.32e+02 strong strong weak moderate moderate strong strong 6.33 6.33 6.0 6.35 6.23 5.94 5.9 6.41 23.6 4.41 29.50 1.37 0.57 1.72 0.49 0.84 2 3 24.3 4 17 23 58 E1
145 IgG1 7a 4.49e-10 1.5e-10 3.94e-08 4.99e-11 9.64e-09 12.6 52.6 114.0 30.7 264.0 663.0 21.9 95.6 213.0 10 38 24 100 1.13e+02 3.13e+02 5.67e+02 10.0 moderate weak moderate weak moderate weak weak 6.02 5.84 5.42 5.43 4.89 4.0 4.7 5.76 99.9 1.89 0.5mg/kg: 661.25|1.5mg/kg: 1907.98 24.20 1.12 0.54 1.61 0.56 0.95 0 2 21.9 0 56 62 94 C3
146 IgG1 7.91e-10 5.76e-10 4.9e-10 1.73e-09 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 moderate moderate moderate moderate weak weak weak 6.18 6.12 5.78 6.14 3.83 3.95 4.87 6.22 4.7 2.97 24.80 1.15 0.46 1.36 0.90 1.53 88 87 25000 96 88 92 92 E3
147 IgG1 2b 1.93e-11 2.02e-11 2.3e-09 1.65e-06 1.83e-10 5.58e-09 5.84 14.6 24.0 404.0 2800.0 7360.0 1.25 4.97 8.95 <0.32 1 3935 14040 1.08e+01 1.25e+01 1.36e+01 100.0 strong strong moderate strong weak moderate moderate 6.29 6.29 5.98 6.31 4.63 5.67 5.43 6.37 100.0 2.78 G485D 0.5mg/kg: 4483.43|1.5mg/kg: 16547.06 21.60 1.00 2.15 6.42 1.60 2.72 0 90 1.25 1 79 83 81 H2
148 IgG1 2d 2.98e-11 1.02e-11 1.85e-09 1.36e-06 3.82 10.2 17.0 371.0 1180.0 1580.0 1.8 7.43 14.1 <0.32 2 >25000 >25000 1.52e+01 2.61e+01 3.59e+01 None strong strong moderate strong weak strong strong 6.3 6.22 5.98 6.22 4.08 5.6 5.39 6.35 100.0 2.94 0.5mg/kg: 6141.31 0 93 1.8 1 71 96 82 B
149 IgG1 5c 5.94e-11 6.81e-11 2.23e-08 9.05e-12 6.56e-10 95.6 244.0 401.0 315.0 1550.0 3740.0 56.5 217.0 456.0 12 38 0.38 5 1.91e+02 5.08e+02 9.02e+02 100.0 strong strong moderate strong weak strong moderate 6.33 6.28 6.0 6.33 5.75 5.81 5.47 6.39 100.0 2.75 A348E 1.5mg/kg: 17131.97|5mg/kg: 54047.50 4 25 56.5 10 64 92 2 G
150 IgG1 2a 2.1e-09 7.7e-10 1.41e-07 1.31e-09 4.53e-08 331.0 981.0 1800.0 1630.0 9700.0 15600.0 90.0 364.0 664.0 171 342 2.44e+02 5.29e+02 8.32e+02 0.0 strong weak moderate strong weak weak moderate 6.21 6.19 5.81 6.12 3.86 5.43 4.91 6.21 100.0 2.51 1.5mg/kg: 1841.74 21.15 0.98 0.68 2.01 0.85 1.44 47 68 90 13 85 89 62 H1
151 IgG1 5b 4.47e-10 6.79e-10 6.31e-09 2.91e-06 1.85e-10 7.1e-09 1310.0 4820.0 9330.0 601.0 2470.0 3640.0 >25000 >25000 >25000 1817 5352 5398 19390 2.50e+04 2.50e+04 2.50e+04 0.0 moderate moderate weak strong weak weak weak 6.25 6.27 5.91 6.26 3.84 3.98 4.9 6.27 46.2 1.88 1.5mg/kg: 6855.20 26.65 1.24 0.45 1.34 0.74 1.26 85 87 25000 79 76 93 59 E4
152 IgG1 5b 3.27e-10 1.37e-09 3.02e-09 1.82e-06 3.65e-10 6.63e-09 1750.0 7580.0 17000.0 383.0 1770.0 2540.0 1000.0 1020.0 1020.0 3671 7621 8896 22602 2.50e+04 2.50e+04 2.50e+04 moderate moderate weak strong weak weak weak 6.23 6.2 5.98 6.26 3.8 3.95 4.83 6.25 31.2 2.56 25.60 1.19 0.60 1.79 0.61 1.03 87 91 1000 92 69 96 68 E4
153 IgG1 2a 5.05e-10 1.44e-10 2.06e-09 6.02e-07 3.8e-10 2.82e-08 28.8 87.0 157.0 >25000 >25000 >25000 35.5 97.4 172.0 15 32 >25000 >25000 2.44e+02 3.85e+02 5.04e+02 30.0 strong moderate weak strong weak moderate strong 6.28 6.3 6.01 6.29 5.19 5.77 5.16 6.34 99.4 1.92 S459P 0.5mg/kg: 1358.37|1.5mg/kg: 5859.62 4 89 35.5 2 83 84 19 H1
154 IgG1 3.35e-10 2.9e-10 8.16e-11 3.85e-10 328.0 807.0 1340.0 220.0 914.0 1820.0 135.0 494.0 797.0 190 544 1.80e+04 3.10e+04 4.25e+04 0.0 moderate moderate weak strong weak weak weak 6.08 6.06 5.78 6.0 3.81 4.0 4.8 6.06 2.4 2.13 0.5mg/kg: 50.30|1.5mg/kg: 1010.60|5mg/kg: 212.60 26.60 1.23 0.57 1.72 0.54 0.92 32 49 135 28 33 26 40 E3
155 IgG1 2c 3.38e-11 1.05e-10 8.42e-10 6.53e-07 8.4e-10 11.5 27.6 44.4 >25000 >25000 >25000 22.7 56.9 94.6 <0.32 3 >25000 >25000 6.46e+01 1.06e+02 1.41e+02 80.0 strong strong weak moderate weak strong strong 6.29 6.23 6.02 6.32 5.04 5.7 5.63 6.36 99.9 3.73 F486E 0.5mg/kg: 3751.21|1.5mg/kg: 12043.94 28.30 1.31 0.38 1.13 0.35 0.59 1 96 22.7 1 98 79 71 B
156 IgG1 2a 4.77e-11 3.15e-11 4.46e-10 2.19e-07 9.71e-10 23.1 60.8 103.0 >25000 >25000 >25000 22.7 60.5 104.0 2 9 >25000 >25000 1.52e+02 5.33e+02 1.11e+03 None strong strong weak moderate moderate moderate moderate 6.33 6.27 6.04 6.33 4.36 5.8 5.09 6.38 97.9 2.56 N481K,del482-484|N487T 0.5mg/kg: 2633.21 27.35 1.27 0.43 1.28 0.51 0.86 1 91 22.7 1 94 98 94 H1
157 IgG1 2a 2.69e-10 6.43e-10 6.65e-09 2.32e-06 8.5e-09 39.8 101.0 171.0 >25000 >25000 >25000 20.7 89.8 186.0 12 28 >25000 >25000 3.07e+02 4.71e+02 6.05e+02 40.0 strong strong moderate weak weak moderate moderate 6.29 6.23 5.98 6.24 4.76 5.65 4.95 6.31 98.2 2.12 D420A|A475D|N460Y|A675D 1.5mg/kg: 5755.23 27.20 1.26 0.52 1.55 0.52 0.87 3 100 20.7 3 95 100 93 H1
158 IgG1 2a 8.27e-11 5.9e-11 1.59e-09 6.82e-07 2.74e-10 32.5 86.9 150.0 >25000 >25000 >25000 17.7 65.6 129.0 3 7 >25000 >25000 3.22e+02 5.96e+02 8.53e+02 30.0 strong strong moderate strong weak moderate strong 6.33 6.23 6.04 6.31 4.49 5.79 5.09 6.38 99.5 2.66 0.5mg/kg: 1957.06|1.5mg/kg: 6576.10 29.60 1.37 0.48 1.43 0.48 0.82 2 92 17.7 2 78 91 79 H2
159 IgG1 2a 1.66e-10 2.23e-10 2.49e-08 78.1 223.0 399.0 >25000 >25000 >25000 30.5 89.5 170.0 11 39 >25000 >25000 6.07e+01 1.55e+02 2.68e+02 0.0 strong moderate moderate weak weak moderate moderate 6.3 6.21 6.03 6.3 4.64 5.8 5.05 6.38 100.0 2.12 S591F|P491T 1.5mg/kg: 7251.31 23.20 1.08 0.54 1.61 0.39 0.66 6 88 30.5 2 71 100 80 H1
160 IgG1 2a 3.77e-10 7.23e-10 1.47e-08 2.66e-10 5.7e-08 62.3 183.0 335.0 >25000 >25000 >25000 28.1 92.6 176.0 3 8 1609 3371 1.70e+00 2.66e+00 3.46e+00 20.0 strong strong moderate strong moderate moderate strong 6.29 6.18 6.01 6.2 5.0 5.7 5.05 6.38 99.6 2.41 N487T|Y369H,N460Y|Y369H,Y489H 1.5mg/kg: 6336.03 25.60 1.19 0.34 1.01 0.39 0.66 4 88 28.1 3 75 98 78 H1
161 IgG1 2.33e-09 1.79e-09 6.03e-07 73.8 243.0 977.0 >25000 >25000 >25000 1000.0 1020.0 1020.0 18 51 >25000 >25000 2.24e+02 5.73e+02 9.91e+02 100.0 strong weak moderate moderate weak weak weak 6.01 5.79 5.51 5.49 3.83 3.97 4.75 5.99 2.7 0.5mg/kg: 50.30|5mg/kg: 150.33 28.25 1.31 0.41 1.22 0.35 0.59 6 93 1000 78 67 93 78 E3
162 IgG1 6b 1.59e-09 1.68e-09 1.91e-07 2.19e-10 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 7435 16198 2.50e+04 2.50e+04 2.50e+04 moderate weak moderate moderate weak weak weak 6.22 6.13 5.85 6.18 3.84 3.96 4.91 6.27 96.8 2.99 29.40 1.36 0.66 1.97 0.57 0.97 79 89 25000 68 75 95 80 A
163 IgG1 2a 7.57e-10 3.31e-10 1.62e-07 8.4e-09 1.53e-07 613.0 2450.0 5100.0 >25000 >25000 >25000 93.5 545.0 1130.0 66 400 >25000 >25000 4.26e+03 3.93e+04 1.44e+05 10.0 strong weak moderate moderate weak moderate moderate 6.23 6.17 5.92 6.2 4.54 5.74 4.96 6.31 100.0 2.28 1.5mg/kg: 2476.54 25.05 1.16 0.52 1.54 0.40 0.68 44 92 93.5 12 81 92 81 H1
164 IgG1 2a 1.72e-10 9.78e-11 2.25e-09 1.05e-06 2.54e-08 45.1 132.0 240.0 >25000 >25000 >25000 20.7 92.0 190.0 10 32 >25000 >25000 3.23e+02 6.06e+02 8.74e+02 30.0 strong moderate moderate strong weak strong moderate 6.23 6.22 6.0 6.26 5.15 5.73 5.03 6.34 97.0 2.64 1.5mg/kg: 4832.12 28.85 1.34 0.45 1.34 0.60 1.02 2 93 20.7 2 83 94 82 H1
165 IgG1 1.01e-08 4.79e-09 7.61e-08 1.09e-08 11100.0 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 7520 17286 2.50e+04 2.50e+04 2.50e+04 0.0 moderate weak moderate weak weak weak weak 3.87 3.68 3.71 3.58 3.82 3.96 4.69 4.49 2.1 5mg/kg: 50.91 26.40 1.23 0.56 1.67 0.24 0.41 85 94 25000 72 76 95 71 E3
166 IgG1 5b 1.76e-10 1.12e-10 8.26e-10 4.75e-07 8.99e-11 1.32e-09 721.0 3990.0 9140.0 >25000 >25000 >25000 >25000 >25000 >25000 223 3222 5894 14375 1.68e+04 3.71e+04 5.90e+04 moderate moderate moderate moderate weak moderate weak 6.31 6.22 5.98 6.27 3.83 4.02 4.93 6.33 32.2 2.79 25.60 1.19 0.36 1.09 0.55 0.93 85 89 25000 74 78 81 69 E4
167 IgG1 2a 1.68e-10 9.84e-11 1.87e-09 6.62e-07 3.82e-10 4.1e-08 47.0 129.0 225.0 1370.0 3640.0 4580.0 35.5 105.0 192.0 12 33 >25000 >25000 5.91e+02 6.88e+02 7.52e+02 20.0 strong strong weak strong weak strong strong 6.28 6.23 5.99 6.26 4.22 5.75 5.42 6.42 99.3 1.72 A475V,S735L|N487T 1.5mg/kg: 4909.76 25.05 1.16 0.61 1.82 0.88 1.48 3 90 35.5 2 83 82 67 H4
168 IgG1 2a 1.31e-10 2.46e-10 2.41e-08 3.77e-10 57.0 211.0 392.0 >25000 >25000 >25000 17.7 54.9 108.0 10 36 3695 11023 1.43e+03 2.01e+03 2.45e+03 30.0 strong strong moderate weak moderate weak moderate 6.29 6.17 6.0 6.23 4.73 5.73 4.97 6.17 100.0 1.78 N460D 0.5mg/kg: 934.70|1.5mg/kg: 5078.05 27.00 1.25 0.46 1.37 0.48 0.81 6 88 17.7 2 94 88 83 H1
169 IgG1 2a 2.57e-10 2.22e-10 3.38e-08 6.53e-10 90.8 304.0 588.0 >25000 >25000 >25000 27.7 90.4 179.0 17 72 15670 >25000 7.11e+02 1.53e+03 2.39e+03 0.0 strong strong moderate weak moderate weak moderate 6.31 6.18 5.99 6.24 5.1 5.73 4.98 6.24 100.0 2.87 D839G 1.5mg/kg: 4836.02 27.65 1.28 0.51 1.51 0.58 0.99 8 87 27.7 1 98 100 95 H1
170 IgG1 5b 3.59e-10 7.48e-10 1.16e-09 6.6e-07 2.55e-10 3.47e-09 1210.0 5480.0 11900.0 >25000 >25000 >25000 871.0 1210.0 1310.0 1001 3347 1241 4183 2.34e+04 3.40e+04 4.23e+04 moderate moderate strong moderate weak weak moderate 6.26 6.16 5.93 6.24 3.87 4.02 5.1 6.3 17.4 2.24 25.45 1.18 0.42 1.25 0.23 0.40 77 87 871 79 79 87 96 E4
171 IgG1 1.15e-10 9.29e-11 5.25e-11 6.59e-10 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 10399 >25000 2.50e+04 2.50e+04 2.50e+04 None moderate moderate moderate strong weak moderate moderate 6.24 6.14 5.93 6.24 3.83 4.02 5.12 6.31 4.5 2.42 26.15 1.21 0.64 1.91 0.42 0.71 84 91 25000 90 100 95 84 E3
172 IgG1 5b 1.29e-10 3.11e-10 9.47e-09 2.57e-06 2.3e-10 7.44e-09 3110.0 18400.0 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2541 16021 4507 18697 2.50e+04 2.50e+04 2.50e+04 moderate weak strong weak weak weak weak 6.27 6.17 6.01 6.27 3.81 3.95 4.96 6.29 33.9 2.06 27.15 1.26 0.51 1.52 0.52 0.87 81 95 25000 51 83 92 76 E4
173 IgG1 1.74e-09 7.61e-10 8.45e-08 >25000 >25000 >25000 >25000 >25000 >25000 2 19 >25000 >25000 1.13e+02 2.86e+02 4.92e+02 40.0 strong weak moderate moderate weak weak moderate 6.2 6.06 5.85 6.08 3.86 5.1 5.02 6.2 2.26 0.5mg/kg: 445.09|5mg/kg: 2113.11 24.75 1.15 0.55 1.64 0.42 0.72 33 95 25000 79 92 94 80 E2
174 IgG >25000 >25000 >25000 1680.0 1700.0 1710.0 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 weak weak moderate moderate weak weak weak 3.84 3.68 3.69 3.59 3.84 3.95 4.71 4.35 8.3 1.59 22.95 1.06 0.42 1.25 0.50 0.85
175 IgG >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 weak weak strong moderate weak moderate weak 3.84 3.7 3.69 3.63 3.82 3.92 4.74 4.39 3.8 1.82 23.95 1.11 0.40 1.19 0.34 0.57
176 IgG >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 weak weak moderate moderate weak weak weak 3.85 3.69 3.7 3.57 3.81 3.95 4.62 4.3 6.7 1.7 23.60 1.10 0.41 1.21 0.47 0.80
177 IgG >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 weak weak moderate moderate weak moderate weak 3.86 3.7 3.71 3.57 3.84 3.93 4.7 4.4 11.2 1.77 24.55 1.14 0.66 1.97 0.58 0.99
178 IgG 5b 6.98e-10 5.1e-10 1.49e-07 3.2e-10 6.83e-09 21000.0 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 moderate weak moderate moderate weak weak weak 6.26 6.14 5.91 6.15 3.83 3.93 4.82 6.2 46.1 1.76 26.75 1.24 0.71 2.13 0.49 0.83 86 90 25000 90 90 95 72 E3
179 IgG 2d 4.7e-10 1.88e-10 2.24e-08 1.85e-09 4.38e-08 685.0 1950.0 3400.0 >25000 >25000 >25000 >25000 >25000 >25000 99 432 24497 >25000 1.94e+02 4.67e+02 7.81e+02 10.0 strong moderate moderate moderate weak weak weak 6.27 6.08 6.0 6.19 4.29 5.4 5.06 6.21 100.0 3.34 T470I 1.5mg/kg: 6142.99 26.15 1.21 0.41 1.24 0.47 0.80 40 96 25000 90 90 79 90 H3
180 IgG 3b 1.07e-09 5.92e-10 9.92e-07 1.19e-10 3.37e-08 772.0 5860.0 21800.0 5.32 28.0 239.0 3720.0 >25000 >25000 19 134 <0.32 1 2.38e+03 2.45e+04 9.60e+04 0.0 moderate moderate weak weak weak weak weak 3.92 4.77 3.72 3.59 3.84 3.96 4.74 5.43 100.0 2.53 P1181L 0.5mg/kg: 50.30|1.5mg/kg: 57.77 25.40 1.18 0.38 1.12 0.39 0.65 65 37 3720 39 100 88 95 B
181 IgG1 5c 8.23e-11 3.23e-11 2.09e-09 1.5e-06 2.72e-11 12.3 26.6 42.7 1.95 6.5 12.1 3.08 9.24 17.8 1 5 1 4 4.98e+01 8.74e+01 1.21e+02 100.0 strong strong moderate moderate moderate moderate moderate 6.36 6.32 5.99 6.35 6.23 5.87 6.62 6.39 72.4 3.76 0.5mg/kg: 2041.25|1.5mg/kg: 10722.74 1 3 3.08 2 96 100 100 H1
182 IgG1 2d 9.44e-11 1.05e-10 1.9e-08 12.2 31.0 52.2 >25000 >25000 >25000 3.9 15.2 27.4 2 6 >25000 >25000 5.88e+01 9.97e+01 1.36e+02 None strong strong moderate strong weak moderate moderate 6.25 6.21 5.96 6.26 6.16 5.88 5.7 6.32 100.0 3.11 0.5mg/kg: 2631.19 0 88 3.9 0 82 100 100 H3
183 IgG 2d 3.23e-11 1.71e-11 6.97e-09 1.66e-09 2.03e-11 3.58e-10 50.2 137.0 229.0 21.3 72.0 141.0 >25000 >25000 >25000 12 35 <0.32 4 2.46e+01 4.92e+01 7.37e+01 70.0 strong strong moderate strong strong strong strong 6.38 6.35 6.05 6.33 6.01 5.78 6.64 6.42 100.0 2.78 1.5mg/kg: 9202.66 0 3 25000 91 61 60 91 B
184 IgG 4.43e-11 2.02e-11 3.44e-08 1.29e-11 1.23e-09 43.9 197.0 540.0 9.44 32.8 68.7 13.5 97.6 439.0 4 16 0.38 1 3.74e+01 2.42e+02 7.19e+02 70.0 strong moderate moderate moderate weak moderate strong 6.32 6.25 5.9 6.31 5.89 5.71 5.21 6.34 100.0 3.26 0.5mg/kg: 1627.71|1.5mg/kg: 4718.71 28.40 1.32 0.21 0.64 7 8 13.5 8 78 86 9 G
185 IgG 2d 1.24e-11 1.12e-11 1.23e-08 4.41 12.2 23.0 >25000 >25000 >25000 11.5 50.6 159.0 1 4 >25000 >25000 5.29e+00 1.00e+01 1.46e+01 70.0 moderate weak moderate moderate weak weak weak 6.26 6.29 5.89 5.27 6.2 5.34 4.75 6.03 100.0 2.75 1.5mg/kg: 12698.69 23.75 1.28 0.63 2.17 0.14 0.32 1 100 11.5 11 100 100 98 H3
186 IgG 1 3.43e-10 1.26e-10 6.1e-09 117.0 374.0 671.0 >25000 >25000 >25000 128.0 406.0 684.0 44 138 >25000 >25000 6.35e+01 1.49e+02 2.44e+02 20.0 strong moderate moderate moderate weak moderate strong 6.28 6.22 5.81 6.27 5.49 5.61 5.12 6.3 99.0 2.42 1.5mg/kg: 4044.10 26.40 1.43 0.20 0.69 0.20 0.44 12 92 128 9 100 100 96 H1
187 IgG 1.83e-10 6.74e-11 5.4e-09 2.51e-08 >25000 >25000 >25000 >25000 >25000 >25000 2 25 >25000 >25000 6.92e+01 2.39e+02 4.93e+02 None strong weak moderate weak weak moderate moderate 6.12 6.04 5.69 5.95 5.72 5.31 4.9 6.09 19.8 2.0 0.5mg/kg: 72.62 21.85 1.18 0.11 0.38 0.17 0.39 39 96 25000 60 98 100 95 E2
188 IgG 1.39e-08 8.44e-09 7.16e-07 2.01e-09 404.0 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 15 242 >12500 >12500 3.40e+02 1.37e+03 3.08e+03 weak weak moderate weak weak weak weak 3.84 3.69 3.66 3.59 3.81 3.93 4.81 4.35 19.4 1.65 27.90 1.51 0.21 0.72 0.16 0.36 39 98 25000 95 95 100 100 E3
189 IgG 2.87e-09 1.01e-09 3.14e-07 108.0 >25000 >25000 1230.0 1260.0 1260.0 2100.0 3220.0 3570.0 22 142 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 strong weak moderate weak weak moderate weak 5.94 5.68 5.3 5.26 5.9 4.53 4.75 5.5 3.0 2.42 del140|del141-144 23.00 1.24 0.07 0.24 0.21 0.47 35 98 2100 96 86 99 82 E3
190 IgG 3.63e-09 1.55e-09 4.07e-07 158.0 >25000 >25000 578.0 2370.0 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 weak moderate moderate weak weak moderate weak 5.56 5.26 4.86 3.94 5.52 3.96 4.78 5.18 3.8 1.62 23.00 1.24 0.27 0.91 0.30 0.68 34 100 25000 100 94 88 87 E3
191 IgG 1.42e-09 7.91e-10 1.18e-07 96.7 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 18 82 >25000 >25000 2.48e+01 5.06e+01 7.68e+01 None moderate weak moderate weak weak weak weak 5.69 5.47 5.03 4.24 3.85 3.98 4.72 5.41 1.4 1.83 del141-144 0.5mg/kg: 50.30 22.45 1.21 0.08 0.28 0.08 0.18 21 97 25000 100 99 92 84 E3
192 IgG 3.29e-11 3.75e-11 9.02e-09 5.67e-09 2.37e-11 53.9 86.1 113.0 488.0 1700.0 2320.0 575.0 1750.0 2350.0 0.43 3 7 30 9.22e+00 2.53e+01 4.56e+01 50.0 strong moderate moderate weak weak moderate moderate 6.29 6.28 5.96 6.28 6.08 5.59 6.08 6.31 100.0 2.22 1.5mg/kg: 5711.47 22.90 1.24 0.12 0.41 0.28 0.61
193 IgG 7.03e-11 1.94e-11 1.06e-08 4.54e-07 4.53e-11 68.3 117.0 163.0 478.0 1110.0 1360.0 410.0 1970.0 3530.0 4 11 70 229 1.24e+01 3.26e+01 5.73e+01 40.0 strong strong moderate weak moderate moderate moderate 6.26 6.19 5.99 6.21 6.09 5.7 5.38 6.25 100.0 1.67 del140-142,V143F 1.5mg/kg: 4552.18 24.10 1.30 0.12 0.41 0.15 0.34
194 IgG 8.36e-11 4.91e-11 3.73e-08 7.01e-07 4.99e-11 8.46e-09 47.2 83.4 117.0 229.0 533.0 926.0 145.0 492.0 803.0 2 17 7 96 1.56e+01 3.87e+01 6.58e+01 30.0 strong moderate moderate moderate weak moderate moderate 6.17 6.1 5.87 6.07 6.08 5.55 5.22 6.07 100.0 2.18 del140-142,V143F 0.5mg/kg: 249.25|1.5mg/kg: 640.17 13.30 0.72 0.14 0.48 0.12 0.28
195 IgG 2.61e-11 2.8e-11 8.64e-09 8.85e-07 1.32e-11 65.2 108.0 146.0 590.0 1710.0 3420.0 >25000 >25000 >25000 2 21 632 2120 9.80e+00 2.38e+01 3.99e+01 30.0 moderate strong moderate strong moderate moderate moderate 6.26 6.19 5.99 6.2 6.12 5.75 5.69 6.34 100.0 1.92 0.5mg/kg: 3777.52 22.65 1.22 0.07 0.23 0.09 0.20
196 IgG 2.98e-10 1.61e-10 5.51e-07 7.83e-11 2.72e-08 85.1 162.0 237.0 296.0 1190.0 1960.0 >25000 >25000 >25000 14 67 100 290 3.16e+01 7.27e+01 1.18e+02 0.0 strong strong moderate weak weak weak weak 6.15 6.05 5.78 6.02 6.05 5.32 5.19 6.02 79.7 2.67 1.5mg/kg: 891.49 23.40 1.26 0.14 0.50 0.07 0.17
197 IgG 7.71e-11 3.51e-11 3.33e-08 7.33e-07 2.03e-11 8.38e-09 29.0 66.1 104.0 286.0 973.0 1990.0 >25000 >25000 >25000 3 21 225 690 8.49e+00 3.25e+01 7.14e+01 None strong moderate moderate strong weak strong strong 6.22 6.15 5.81 6.14 6.1 5.52 5.15 6.09 93.0 2.75 0.5mg/kg: 379.56 24.75 1.34 0.25 0.85 0.18 0.41
198 IgG 4.14e-11 2.69e-11 3.33e-08 1.17e-06 1.64e-11 4.34e-09 61.0 130.0 198.0 74.0 211.0 396.0 320.0 917.0 1570.0 7 39 24 86 6.18e+00 2.79e+01 6.73e+01 30.0 strong moderate moderate strong weak moderate moderate 6.21 6.14 5.89 6.12 6.09 5.25 4.94 6.13 100.0 2.41 0.5mg/kg: 333.11|1.5mg/kg: 1564.84 24.20 1.31 0.03 0.10 0.14 0.31
199 IgG 1 2.3e-10 1.42e-10 8.33e-09 3.59e-07 3.29e-10 73.4 165.0 257.0 >25000 >25000 >25000 >25000 >25000 >25000 29 122 >25000 >25000 2.53e+01 7.36e+01 1.37e+02 None strong strong moderate weak weak moderate moderate 6.22 6.17 5.86 6.14 6.1 5.58 5.16 6.22 99.0 3.54 0.5mg/kg: 288.99 26.25 1.42 0.13 0.45 0.26 0.58 1 100 25000 76 100 100 100 H1
200 IgG 2a 5.6e-11 7.51e-11 4.61e-08 9.41e-09 60.6 182.0 340.0 >25000 >25000 >25000 11.6 50.9 111.0 13 61 >25000 >25000 2.71e+01 9.19e+01 1.88e+02 moderate moderate weak weak weak moderate weak 6.17 6.07 5.72 5.18 4.53 3.75 4.86 5.43 100.0 0.375 23.00 1.24 0.12 0.43 0.17 0.38 25 100 11.6 11 99 100 100 H1
201 IgG 2d 3.51e-11 1.78e-11 2.35e-09 7.13e-07 9.49 25.4 44.0 >25000 >25000 >25000 >25000 >25000 >25000 <0.32 <0.32 >25000 >25000 2.63e+01 4.59e+01 6.35e+01 strong moderate strong strong weak moderate moderate 6.03 5.99 5.7 5.98 5.8 5.63 5.21 6.23 99.4 4.58 F490L|F486I 24.40 1.32 0.04 0.16 0.13 0.29 8 100 25000 100 100 100 100 H3
202 IgG1 2a 4.48e-10 2.34e-10 1.26e-10 4.34e-08 741.0 2260.0 4380.0 >25000 >25000 >25000 330.0 >25000 >25000 477 2096 6.05e+03 1.47e+04 2.50e+04 0.0 strong weak weak weak weak strong strong 6.28 6.12 5.98 6.19 5.84 5.06 4.93 6.25 100.0 2.24 1.5mg/kg: 5992.57 25.65 1.39 0.13 0.45 0.17 0.39 46 72 330 25 96 100 100 H1
203 IgG1 2d 2.4e-11 1.43e-11 3.72e-10 1.21e-07 3.03e-08 3.32e-08 14.4 46.5 86.3 >25000 >25000 >25000 11.3 31.6 57.1 9 24 >25000 >25000 6.73e+00 1.45e+01 2.27e+01 strong moderate strong moderate weak moderate moderate 6.07 6.02 5.72 6.0 6.39 4.86 4.88 6.2 99.2 0.952 21.35 1.15 0.12 0.40 0.24 0.53 100 100 11.3 99 100 100 100 H3
204 IgG1 2d 8.75e-11 3.75e-11 2.67e-10 2.48e-07 8.16e-08 5.77e-08 31.0 79.4 131.0 >25000 >25000 >25000 >25000 >25000 >25000 4 10 >25000 >25000 6.07e+01 1.01e+02 1.36e+02 90.0 strong strong strong moderate moderate moderate moderate 6.03 5.97 5.66 5.96 6.45 5.22 5.01 6.2 97.8 2.06 1.5mg/kg: 13579.78 26.30 1.42 0.12 0.41 0.13 0.29 100 100 25000 100 100 100 100 H3
205 IgG1 2d 1.34e-10 3.68e-11 1.67e-09 4.75e-07 3.69e-08 17.3 50.1 89.2 >25000 >25000 >25000 139.0 453.0 788.0 3 21 >25000 >25000 1.66e+01 4.64e+01 8.46e+01 None strong moderate strong strong moderate moderate moderate 6.0 5.99 5.66 5.96 6.49 5.08 4.95 6.23 99.0 2.22 0.5mg/kg: 1508.09 24.90 1.35 0.10 0.34 0.14 0.30 0 100 139 26 94 100 100 H3
206 IgG1 1.01e-10 8.16e-11 4.85e-08 >25000 >25000 >25000 >25000 >25000 >25000 1 4 >25000 >25000 2.18e+00 5.35e+00 9.04e+00 90.0 moderate weak moderate moderate weak moderate moderate 6.03 5.98 5.68 5.94 6.37 4.72 4.92 6.12 0.934 1.5mg/kg: 183.65 25.70 1.39 0.19 0.66 0.14 0.30 55 98 25000 81 100 93 100 E2
207 IgG1 1.3e-09 5.66e-10 4.16e-07 1.45e-07 76.2 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 14 33 >25000 >25000 1.93e+01 5.26e+01 9.46e+01 None moderate weak moderate weak weak moderate moderate 5.82 5.81 5.47 5.51 5.64 4.82 5.26 5.56 11.8 1.15 0.5mg/kg: 50.30 23.65 1.28 0.12 0.43 0.20 0.44 25 96 25000 100 93 100 100 E3
208 IgG1 2c 5.22e-11 2.65e-11 5.08e-09 1.37e-06 2.47e-11 62.6 94.8 126.0 51.3 120.0 192.0 7.21 53.3 145.0 77 147 >25000 >25000 8.34e+01 2.01e+02 3.38e+02 strong weak moderate strong weak moderate weak 6.05 6.01 5.71 5.99 4.63 4.58 4.82 6.2 100.0 1.93 24.70 1.34 0.25 0.86 0.17 0.37 1 20 7.21 0 97 100 98 H1
209 IgG1 1.41e-07 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 weak weak weak weak weak moderate moderate 3.29 3.1 2.99 2.77 3.68 4.76 5.31 4.34 32.7 0.632 23.60 1.28 0.06 0.20 0.18 0.41 100 100 92 88 92 100
210 IgG 3.21e-09 1.37e-09 2.86e-07 156.0 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 209 2382 3.82e+01 1.30e+02 2.65e+02 80.0 moderate weak moderate weak weak weak weak 5.65 5.63 5.23 5.33 5.49 4.81 5.26 5.54 4.7 1.35 1.5mg/kg: 7717.11 25.35 1.37 0.09 0.29 0.25 0.56 1 1 25000 2 17 18 56 E3
211 IgG1 2d 8.99e-12 7.69e-12 2.01e-10 1.02e-07 3.98e-08 5.16 10.5 15.9 >25000 >25000 >25000 2.39 8.61 17.1 0.5 2 4.54e+00 5.64e+00 6.41e+00 None strong strong moderate moderate weak moderate weak 6.16 6.05 5.76 5.98 6.42 4.23 4.97 6.15 99.6 1.26 0.5mg/kg: 2316.08 0 98 2.39 0 100 98 100 H3
212 IgG1 3.67e-11 1.72e-11 6.3e-10 3.17e-07 2.04e-11 7.12e-08 71.0 152.0 241.0 29.2 109.0 215.0 61.3 243.0 461.0 30 100 17 49 7.44e+01 1.09e+02 1.36e+02 20.0 moderate strong strong moderate weak moderate weak 6.1 6.01 5.71 5.98 4.93 4.96 5.07 6.17 96.6 1.76 N440D 0.5mg/kg: 1225.84|1.5mg/kg: 3745.19 25.45 1.38 0.08 0.27 0.21 0.47 1 0 61.3 0 90 97 99
213 IgG1 3b 3.64e-11 1.72e-11 6.74e-11 8.74e-08 2.74e-11 1.08e-09 28.4 89.8 160.0 33.6 102.0 189.0 64.8 122.0 189.0 11 32 21 61 7.97e+01 1.25e+02 1.62e+02 20.0 strong moderate strong strong weak moderate moderate 6.09 6.01 5.71 5.95 4.82 5.2 5.22 6.05 98.0 2.88 G504D 0.5mg/kg: 1644.34|1.5mg/kg: 6022.87 25.60 1.38 0.09 0.29 0.11 0.24 5 6 64.8 5 97 100 100 A
214 IgG1 6b 1.24e-10 4.4e-11 7.1e-11 2.94e-06 3.93e-11 338.0 945.0 1220.0 153.0 400.0 688.0 849.0 1310.0 1570.0 158 512 147 435 8.56e+02 1.85e+03 2.91e+03 0.0 moderate moderate strong strong weak moderate moderate 6.09 5.99 5.72 5.95 4.7 4.94 5.12 6.06 95.5 1.99 1.5mg/kg: 6771.51 25.25 1.36 0.06 0.19 0.42 0.94 8 9 849 8 100 100 100 A
215 IgG1 4a 3.24e-11 1.12e-11 9.05e-10 6.19e-07 20.7 61.5 111.0 >25000 >25000 >25000 >25000 >25000 >25000 1 6 >25000 >25000 3.89e+01 9.42e+01 1.58e+02 60.0 strong weak strong strong weak moderate moderate 6.07 6.0 5.71 5.97 5.09 4.72 4.86 6.2 96.1 2.46 0.5mg/kg: 6187.27 25.45 1.38 0.14 0.47 0.12 0.28 1 100 25000 98 100 100 100 H1
216 IgG1 5.4e-09 2.59e-09 3.85e-09 3560.0 8730.0 14300.0 >25000 >25000 >25000 615.0 >25000 >25000 671 2075 2.50e+04 2.50e+04 2.50e+04 0.0 moderate strong moderate strong moderate moderate moderate 5.84 5.77 5.5 5.71 4.0 4.84 5.19 5.68 23.7 1.7 1.5mg/kg: 120.58 27.25 1.47 0.17 0.59 0.16 0.36
217 IgG1 5.17e-10 6.33e-10 4.46e-10 636.0 1350.0 1990.0 702.0 1580.0 2370.0 >25000 >25000 >25000 35 520 864 2489 3.84e+03 5.97e+03 7.74e+03 0.0 strong moderate strong strong strong strong strong 5.96 5.91 5.62 5.88 4.59 5.03 5.06 5.93 77.6 0.821 1.5mg/kg: 699.36 27.45 1.48 0.14 0.50 0.21 0.48
218 IgG1 2.64e-10 4.84e-11 6.07e-10 300.0 603.0 796.0 120.0 470.0 869.0 20.8 84.1 184.0 58 193 437 744 4.54e+03 6.52e+03 8.06e+03 None strong strong strong strong moderate strong strong 6.05 6.0 5.7 6.09 5.38 5.11 4.85 6.17 96.5 3.86 0.5mg/kg: 387.92 47.25 1.68 5.00 21.28 2.23 1.59
219 IgG1 >25000 >25000 >25000 19.1 91.5 185.0 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 weak weak weak weak weak moderate weak 3.37 3.11 3.01 2.75 3.65 4.71 5.31 4.34 2.5 0.658 30.75 1.09 0.49 2.11 1.16 0.82
220 IgG1 4.27e-10 1.84e-10 1.89e-11 1.47e-10 8.03e-10 >25000 >25000 >25000 >25000 >25000 >25000 71.2 292.0 587.0 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 moderate weak moderate moderate weak moderate moderate 6.0 5.95 5.62 5.86 4.41 4.93 5.2 5.92 0.1 0.493 31.95 1.13 0.15 0.66 0.73 0.53 93 97 71.2 94 90 94 94
221 IgG1 1.55e-09 9.17e-10 3.55e-08 1.27e-08 150.0 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 91 361 >25000 >25000 1.94e+02 7.80e+02 1.76e+03 60.0 moderate weak moderate moderate weak moderate moderate 5.85 5.87 5.5 5.63 3.9 4.79 5.21 5.64 1.1 0.416 1.5mg/kg: 100.06 34.75 1.23 0.23 1.00 0.82 0.59 97 100 25000 94 99 100 100 E3
222 IgG1 4.44e-11 5.09e-11 5.94e-10 >25000 >25000 >25000 >25000 >25000 >25000 91 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 moderate weak weak weak weak weak weak 5.97 5.94 5.62 5.73 3.89 4.61 5.15 5.65 0.9 0.334 36.60 1.30 0.17 0.74 0.69 0.49 94 100 25000 100 97 100 99 E3
223 IgG1 9.54e-11 4.71e-11 1.27e-09 3.28e-09 39.4 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 15 67 >25000 >25000 1.80e+02 3.54e+02 5.26e+02 10.0 moderate moderate moderate strong weak moderate moderate 6.1 6.0 5.71 5.95 4.79 4.48 4.93 6.12 8.6 1.03 1.5mg/kg: 362.34 36.55 1.30 0.29 1.26 1.05 0.75 23 94 25000 34 99 100 21 E2
224 IgG1 3.5e-10 2.16e-10 4.78e-10 2.31e-10 1.41e-09 >25000 >25000 >25000 >25000 >25000 >25000 1.01 0.989 0.981 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 moderate moderate moderate strong weak moderate moderate 6.05 5.95 5.67 5.86 4.46 4.94 5.23 5.93 4.0 1.2 47.60 1.69 6.42 27.32 2.77 1.98 92 95 1.01 91 100 100 97
225 IgG1 6.49e-10 4.69e-10 3.42e-10 5.86e-10 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 moderate strong moderate strong weak moderate moderate 6.05 5.97 5.67 5.82 4.08 4.78 5.21 5.77 3.7 0.586 34.60 1.23 1.64 6.98 1.39 0.99 84 100 25000 100 100 100 100 E3
226 IgG1 7.87e-11 1.07e-10 1.27e-09 >25000 >25000 >25000 >25000 >25000 >25000 15652 >25000 2.50e+04 2.50e+04 2.50e+04 moderate moderate weak weak weak moderate moderate 6.01 5.96 5.67 5.82 4.04 4.68 5.15 5.83 1.8 0.647 33.45 1.19 0.12 0.51 0.14 0.10 78 100 25000 100 100 100 100 E3
227 IgG1 5.42e-10 2.68e-10 2.78e-10 4.05e-08 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 moderate moderate moderate moderate weak moderate weak 6.03 5.97 5.68 5.92 4.53 4.65 5.04 5.99 4.8 0.912 29.50 1.05 0.34 1.43 0.11 0.08 91 99 25000 100 100 100 97 E3
228 IgG1 4.92e-10 2.92e-10 2.37e-10 5.02e-10 1110.0 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 moderate strong moderate strong weak moderate moderate 6.01 5.96 5.65 5.81 4.08 4.71 5.2 5.77 0.9 0.339 22.86 0.81 0.31 1.32 0.32 0.23 100 100 25000 100 100 100 100 E3
229 IgG1 2.99e-10 2.18e-10 5.73e-10 1.57e-10 1.58e-09 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 moderate moderate weak weak weak moderate moderate 5.98 5.94 5.66 5.91 4.53 4.56 4.94 6.01 0.7 1.9 41.40 1.47 0.12 0.49 0.82 0.59 100 100 25000 100 97 100 100 E3
230 IgG1 5b 3.72e-10 2.35e-10 5.29e-10 3.8e-07 2.42e-10 1.84e-09 2940.0 14300.0 >25000 >25000 >25000 >25000 >25000 >25000 >25000 5541 19055 3543 11203 1.42e+04 3.68e+04 6.43e+04 moderate weak moderate moderate weak moderate weak 5.99 5.96 5.65 5.88 4.16 4.66 5.1 5.9 18.8 0.487 39.45 1.40 0.26 1.11 0.94 0.67 78 92 25000 82 77 95 92
231 IgG1 2b 3.81e-11 8.55e-12 1.57e-10 5.37e-08 6.64e-12 1.26e-09 9.1 24.9 42.5 3.35 9.41 16.7 1020.0 >25000 >25000 <0.32 0.71 <0.32 <0.32 7.39e+00 1.42e+01 2.09e+01 50.0 strong weak strong strong moderate moderate strong 5.97 6.0 5.66 5.88 4.77 4.4 4.82 6.15 99.1 3.43 1.5mg/kg: 8672.51 42.85 1.52 2.46 10.49 1.80 1.29 0 0 1020 22 70 72 70 H2
232 IgG1 5c 2.31e-10 1.67e-10 1.58e-09 4.12e-07 1.57e-10 4.92e-09 109.0 280.0 469.0 408.0 1060.0 1390.0 3240.0 >25000 >25000 148 523 498 2160 7.55e+02 1.89e+03 3.23e+03 10.0 strong moderate strong strong moderate moderate moderate 6.0 5.96 5.63 5.83 4.4 4.38 4.98 5.91 21.3 2.4 1.5mg/kg: 4886.74 41.75 1.48 0.37 1.57 0.71 0.51 14 32 3240 79 27 46 47 G
233 IgG1 1.6e-09 5.29e-10 2.13e-09 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 strong weak moderate weak weak moderate moderate 5.84 5.82 5.51 5.76 4.13 4.66 5.08 5.84 0.8 2.33 36.25 1.29 0.39 1.64 0.79 0.56 89 99 25000 95 93 96 100
234 IgG1 1 1.54e-09 3.64e-10 2.32e-08 3.35e-10 222.0 658.0 1190.0 150.0 416.0 832.0 28.9 119.0 261.0 319 1442 1.18e+03 1.90e+03 2.51e+03 strong weak moderate weak weak moderate moderate 5.78 5.85 5.48 5.67 3.48 4.05 4.88 5.69 38.5 2.49 35.50 1.26 0.28 1.17 0.82 0.59 13 6 28.9 3 3 6 5 H1
235 IgG1 2.13e-11 1.13e-11 2.56e-10 1.19e-07 1.36e-11 2.76e-08 5.68 16.0 27.7 8.74 24.4 42.4 4.37 12.4 22.9 6 20 2 9 1.50e+01 2.33e+01 3.01e+01 moderate moderate strong strong moderate moderate weak 6.11 6.02 5.72 5.97 4.95 4.61 4.98 6.06 97.4 0.993 0.5mg/kg: 2514.91 35.35 1.26 2.35 10.00 3.11 2.22 0 0 4.37 0 100 90 86 A
236 IgG1 1.74e-11 9.31e-12 4.43e-11 3.09e-08 7.9e-12 1.46e-09 9.59 28.9 51.3 8.73 23.3 40.2 10.0 29.1 53.3 <0.32 <0.32 1.68e+01 2.27e+01 2.70e+01 50.0 strong strong strong strong strong moderate moderate 6.15 6.07 5.74 6.02 5.3 4.55 4.78 6.02 99.2 1.83 1.5mg/kg: 7854.60 41.65 1.48 0.34 1.47 0.59 0.42 0 0 10 0 62 75 65 H1
237 IgG1 8.49e-11 4.34e-11 1.05e-10 3.2e-08 1.38e-10 5.45e-08 37.2 98.7 165.0 480.0 2290.0 >25000 32.6 93.0 164.0 7 93 982 2985 1.80e+02 3.54e+02 5.26e+02 0.0 moderate strong moderate moderate weak moderate moderate 6.09 6.01 5.7 5.94 4.76 4.65 4.91 6.09 97.2 4.28 1.5mg/kg: 6489.24 42.15 1.50 2.98 12.66 1.90 1.36 100 99 32.6 83 87 100 100 H2
238 IgG1 4c 1.43e-10 1.33e-10 8.73e-10 3.87e-07 9.57e-11 9.24e-10 260.0 810.0 1450.0 >25000 >25000 >25000 126.0 287.0 437.0 518 2418 3.54e+03 1.42e+04 3.20e+04 0.0 32.3 0.696 1.5mg/kg: 7996.73 38.60 1.37 0.10 0.43 0.72 0.51 57 93 126 90 35 100 85 G
239 IgG1 2a 1.41e-10 3.65e-11 7.74e-09 3.85e-06 5.67e-11 3.08e-08 54.8 149.0 264.0 24.5 84.2 190.0 129.0 330.0 501.0 25 85 4 23 3.03e+02 5.64e+02 8.11e+02 0.0 98.3 0.997 0.5mg/kg: 1405.73|1.5mg/kg: 3947.68 36.90 1.31 0.28 1.21 1.33 0.95 3 10 129 4 100 100 100 H2
240 IgG >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 3885 12310 moderate moderate weak moderate weak weak moderate 4.07 3.88 3.78 5.2 3.08 4.41 5.02 5.52 11.5 0.858
241 IgG1 7a 4.75e-11 4.72e-11 7.51e-10 6.59e-07 3.11e-11 1.76e-09 32.1 113.0 199.0 30.7 88.9 160.0 30.8 67.1 106.0 1 7 8 35 7.06e+01 1.05e+02 1.33e+02 70.0 weak weak moderate strong weak weak weak 3.92 3.68 3.76 3.42 4.16 4.58 5.03 3.91 100.0 1.45 S371F 1.5mg/kg: 9832.44 33.70 1.20 0.12 0.51 0.78 0.55 1 2 30.8 0 92 100 100 C1
242 IgG1 7a 7.15e-11 6.52e-11 6.59e-10 4.91e-07 2.75e-11 5.12e-09 32.9 111.0 195.0 171.0 609.0 911.0 169.0 350.0 499.0 1 13 101 172 6.35e+01 1.16e+02 1.64e+02 80.0 weak weak weak moderate weak weak weak 3.94 3.68 3.8 3.4 4.24 4.58 5.0 3.98 100.0 1.13 S371F,P384L|del374,P384L|del374-376,P384L 0.5mg/kg: 7552.94 35.95 1.28 2.73 11.60 1.79 1.28 7 12 169 1 91 98 99 C3
243 IgG1 7a 9.88e-11 9.08e-11 2.63e-09 1.61e-06 3.75e-11 1.73e-09 13.8 42.9 76.3 45.6 115.0 188.0 49.3 209.0 424.0 8 22 26 79 6.62e+01 9.27e+01 1.13e+02 100.0 moderate moderate weak weak weak weak weak 3.91 3.69 3.76 5.11 4.22 4.56 5.05 3.96 100.0 0.908 S375F,N703S|N544S,N703S 1.5mg/kg: 16820.39 18 32 49.3 5 87 98 100 C3
244 IgG1 7a 9.49e-11 8.81e-11 1.38e-09 1.14e-06 8.39e-11 8.57e-09 19.1 59.1 106.0 363.0 1090.0 1680.0 187.0 778.0 >25000 234 566 6.95e+01 1.00e+02 1.24e+02 90.0 weak moderate weak moderate weak weak weak 3.93 4.23 3.79 3.42 5.09 4.72 5.02 5.24 92.9 1.03 S375T|Y508H|S371F 0.5mg/kg: 2695.93|1.5mg/kg: 13640.24 34.15 1.21 0.18 0.77 1.24 0.89 3 4 187 0 80 91 99 C3
245 IgG1 3.21e-10 2.28e-10 1.06e-08 1.92e-10 31.8 >25000 >25000 3610.0 >25000 >25000 >25000 >25000 >25000 1 8 12141 >25000 2.27e+03 1.58e+04 4.93e+04 0.0 moderate moderate weak moderate weak weak weak 6.37 6.18 5.96 6.18 5.62 4.78 5.13 6.31 0.92 1.5mg/kg: 210.77 37.90 1.35 0.11 0.46 1.21 0.86 19 64 25000 48 95 95 61 E2
246 IgG1 4.78e-10 5.22e-10 7.83e-09 7.49e-11 31.1 92.7 271.0 251.0 >25000 >25000 >25000 >25000 >25000 19 39 12 33 1.28e+02 1.95e+02 2.50e+02 40.0 strong strong moderate strong weak weak weak 5.45 5.2 4.96 4.84 3.11 4.63 5.05 5.82 12.1 0.372 del141-144 1.5mg/kg: 52.97 39.30 1.28 0.65 0.86 0.14 1.35 5 34 25000 93 100 98 100 E2
247 IgG1 1.03e-08 7.68e-09 3.22e-07 78.3 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 12 29 >25000 >25000 1.31e+02 3.24e+02 5.51e+02 moderate moderate weak moderate weak weak weak 5.71 5.59 5.25 5.32 3.18 4.73 5.0 6.0 5.8 0.882 del141-144 38.15 1.24 4.83 6.35 0.47 4.65 32 100 25000 79 100 95 84 E3
248 IgG1 1.74e-09 4.51e-09 1.06e-07 63 804 >25000 >25000 1.24e+03 2.32e+03 3.34e+03 weak moderate weak strong weak moderate moderate 5.32 5.4 5.13 5.22 4.3 4.64 5.09 5.07 24.7 0.816 T67I 39 98 92 96 100 88
249 IgG1 2a 7.19e-11 2.43e-11 9.81e-09 2.86e-08 48.9 123.0 236.0 >25000 >25000 >25000 59.5 78.1 93.8 10 258 >25000 >25000 1.95e+03 3.08e+03 4.01e+03 40.0 strong moderate moderate strong weak weak weak 6.14 6.08 5.85 6.05 4.64 4.78 5.0 6.22 100.0 0.776 N1023Y 1.5mg/kg: 9652.42 31.50 1.02 1.10 1.45 0.07 0.65 2 100 59.5 0 98 100 89 H4
250 IgG1 6a 2.19e-10 1.13e-10 4.14e-10 3.21e-07 5.84e-11 5.7e-09 1090.0 3450.0 6370.0 1490.0 5280.0 7440.0 >25000 >25000 >25000 131 2160 557 1664 1.69e+03 2.75e+03 3.65e+03 0.0 moderate moderate moderate strong weak moderate moderate 6.03 6.34 5.87 6.05 5.15 4.83 5.08 6.02 7.5 0.328 1.5mg/kg: 2650.09 32.40 1.05 2.33 3.06 0.26 2.60 85 100 25000 100 94 100 88 A
251 IgG1 5a 1.64e-10 1.38e-10 1.71e-10 6.44e-08 6.18e-11 1.38e-09 104.0 250.0 412.0 17 391 34 102 3.40e+02 6.93e+02 1.05e+03 10.0 strong strong moderate moderate weak weak weak 6.3 6.25 5.89 6.17 4.91 4.9 5.16 6.27 3.9 1.43 0.5mg/kg: 1868.20|1.5mg/kg: 5311.08 6.20 0.20 0.93 1.22 0.07 0.70 13 11 9 22 92 81 G
252 IgG1 2a 4.06e-10 1.14e-10 1.51e-08 1.05e-08 1.67e-07 123.0 305.0 619.0 >25000 >25000 >25000 45.2 127.0 239.0 64 150 476 856 2.89e+02 6.86e+02 1.14e+03 0.0 strong moderate strong moderate weak weak moderate 6.27 6.22 6.01 6.14 4.83 4.8 5.05 6.25 100.0 0.558 1.5mg/kg: 3961.93 35.30 1.15 1.44 1.89 0.07 0.75 10 100 45.2 4 98 100 100 H4
253 IgG1 1.06e-09 8.58e-10 2.7e-08 22.6 77.1 171.0 >25000 >25000 >25000 >25000 >25000 >25000 1.72e+02 5.61e+02 1.12e+03 moderate weak moderate moderate weak weak weak 6.39 6.22 5.98 6.23 5.3 4.66 5.09 6.31 9.0 0.395 del141 32.65 1.06 5.21 6.86 0.53 5.30 7 100 25000 100 100 100 100 E3
254 IgG1 2.4e-11 1.3e-11 7.93e-09 3.79e-10 21.4 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 <0.32 3 22 71 1.71e+01 4.45e+01 7.79e+01 80.0 strong moderate moderate moderate weak moderate moderate 6.46 6.14 6.01 6.19 5.14 4.78 4.94 6.33 6.0 1.09 1.5mg/kg: 5078.90 31.60 1.03 0.12 0.16 0.18 1.85 30 97 25000 66 100 100 34 E2
255 IgG1 2.49e-11 2.01e-11 8.17e-09 >25000 >25000 >25000 >25000 >25000 >25000 <0.32 1 287 827 1.54e+01 7.56e+01 1.92e+02 30.0 strong weak moderate weak weak weak moderate 6.47 6.33 6.04 6.23 5.26 4.93 5.64 6.32 8.6 0.722 del141|E682K 1.5mg/kg: 3002.57 35.35 1.15 0.02 0.03 0.33 3.30 47 100 25000 66 85 100 48 E2
256 IgG1 4.49e-11 3.33e-11 5.64e-09 >25000 >25000 >25000 >25000 >25000 >25000 1 3 >25000 >25000 6.38e+00 1.29e+01 1.96e+01 50.0 strong weak moderate weak weak weak weak 6.49 6.31 6.07 6.3 5.4 4.99 5.22 6.32 7.0 0.887 del241-247 1.5mg/kg: 1455.69 38.10 1.24 0.35 0.47 0.25 2.50 92 97 25000 94 100 90 93 E2
257 IgG1 2.24e-11 1.62e-11 2.19e-09 1.48e-10 30.3 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 1 3 1334 4193 5.79e+00 1.66e+01 3.07e+01 40.0 strong moderate moderate weak weak moderate moderate 6.5 6.17 6.06 6.19 5.43 4.77 5.05 6.35 0.5 0.468 0.5mg/kg: 248.87|1.5mg/kg: 1129.40 37.50 1.22 0.05 0.07 0.67 6.70 32 95 25000 49 89 96 33 E2
258 IgG1 1.29e-11 1.37e-11 1.24e-08 4.7e-10 118.0 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 <0.32 1 >25000 >25000 1.33e+01 5.98e+01 1.44e+02 70.0 moderate weak weak moderate weak weak moderate 6.45 6.0 5.91 6.0 5.03 4.75 5.07 6.3 6.1 0.382 1.5mg/kg: 903.31 30.85 1.00 0.04 0.05 0.35 3.50 51 100 25000 74 97 100 31 E2
259 IgG1 1 3.38e-11 2.13e-11 2.1e-09 1.1e-06 24.5 71.3 130.0 >25000 >25000 >25000 8.06 42.1 96.2 2 9 >25000 >25000 5.74e+01 9.89e+01 1.36e+02 100.0 strong moderate moderate moderate weak moderate moderate 6.31 6.32 5.91 6.19 5.16 4.92 5.1 6.25 100.0 0.28 E1195A|del375-377,P384L 1.5mg/kg: 13172.90 35.75 1.16 0.12 0.16 1.02 10.25 1 97 8.06 0 90 96 93 H1
260 IgG1 2c 1.59e-11 1.07e-11 6.96e-11 5.87e-08 1.15e-08 9.37e-09 11.7 31.1 53.7 >25000 >25000 >25000 66.4 325.0 831.0 <0.32 2 >25000 >25000 1.83e+01 2.64e+01 3.27e+01 10.0 strong strong moderate moderate weak weak weak 6.36 6.54 6.24 6.66 5.67 4.69 5.06 6.22 100.0 1.61 del450|del449|Y449D 1.5mg/kg: 3179.28 39.00 1.27 0.58 0.77 0.20 2.00 1 100 66.4 2 9 4 90 B
261 IgG1 5b 2.23e-10 3.57e-10 2.78e-10 2.08e-07 1.34e-10 1.56e-09 4680.0 17800.0 24800.0 >25000 >25000 >25000 449 2465 905 3490 5.08e+03 9.28e+03 1.32e+04 10.0 strong moderate moderate strong weak moderate moderate 6.23 6.24 5.92 5.99 4.61 4.74 5.13 6.14 30.9 2.99 1.5mg/kg: 5999.07 39.95 1.30 5.38 7.07 0.72 7.20 84 85 25000 75 73 78 68 E4
262 IgG1 4a 2.65e-10 8.49e-11 4.67e-09 4.23e-06 >25000 >25000 >25000 >25000 >25000 >25000 39 185 >25000 >25000 2.65e+03 3.11e+03 3.42e+03 strong weak moderate strong weak weak moderate 6.41 6.61 6.17 6.55 5.47 4.97 5.09 6.27 100.0 3.21 44.65 1.45 0.81 1.07 0.04 0.40 57 100 25000 90 100 100 95 H1
263 IgG1 7b 3.58e-10 2.16e-10 8.61e-11 1.07e-07 1.14e-10 2.72e-08 1180.0 3800.0 5200.0 803.0 1620.0 1990.0 244.0 >25000 >25000 232 683 7.47e+03 2.56e+04 5.26e+04 40.6 2.43 36.75 1.19 0.54 0.71 0.24 2.40 72 60 244 33 100 91 93 C1
264 IgG1 6.2e-11 4.42e-11 4.77e-08 6.67e-10 >25000 >25000 >25000 >25000 >25000 >25000 <0.32 2 13913 >25000 5.30e+00 1.54e+01 2.88e+01 moderate weak moderate weak weak strong strong 6.4 6.12 5.87 5.85 4.88 4.6 5.01 6.32 6.3 2.38 32.25 1.05 0.70 0.93 0.38 3.80 68 100 25000 70 100 99 37 E2
265 IgG1 2a 3.68e-11 2.43e-11 1.55e-09 1.1e-06 4.76e-10 3.45e-08 12.2 41.7 80.8 >25000 >25000 >25000 3.02 17.7 40.2 <0.32 4 12587 >25000 1.84e+01 3.21e+01 4.45e+01 strong strong strong weak weak strong strong 6.28 6.28 5.82 6.19 4.93 4.71 4.93 6.18 100.0 3.15 A475D|F486L|N487D|E484A 42.85 1.39 1.15 1.51 0.15 1.55 1 100 3.02 1 100 100 100 H4
266 IgG1 2a 8.43e-11 8.04e-11 2.41e-09 1.8e-06 4.48e-10 3.98e-08 18.7 60.6 116.0 90.0 366.0 1790.0 11.0 32.9 53.7 2 10 4.47e+01 9.16e+01 1.39e+02 60.0 strong strong strong weak weak moderate moderate 6.3 6.43 5.92 6.31 5.04 4.83 5.19 6.22 100.0 2.84 1.5mg/kg: 6491.44 36.85 1.20 0.35 0.47 0.23 2.30 1 18 11 1 88 99 100 H4
267 IgG1 2a 5.28e-11 9.65e-11 1.95e-09 1.74e-06 7.31e-09 16.3 45.6 81.0 >25000 >25000 >25000 4.95 16.2 29.9 1 4 2.13e+01 8.27e+01 1.83e+02 60.0 moderate moderate moderate strong weak moderate moderate 6.11 5.79 5.28 5.58 4.53 4.58 5.11 6.0 100.0 3.02 S371F 0.5mg/kg: 50.30|1.5mg/kg: 86.02 43.35 1.41 0.50 0.66 0.09 0.90 1 99 4.95 0 91 100 100 H4
268 IgG1 4b 3.71e-11 2.06e-11 2.29e-09 1.9e-06 3.13e-11 1.37e-10 9.28 23.2 38.0 4.8 12.4 20.1 >25000 >25000 >25000 10 25 2.19e+01 3.13e+01 3.85e+01 70.0 moderate weak moderate weak weak moderate moderate 5.12 5.35 3.87 3.66 6.0 4.65 4.88 5.71 100.0 5.6 R444K|G447V|Y449C 0.5mg/kg: 2053.25|1.5mg/kg: 6582.65 43.35 1.41 0.38 3.75 1 0 25000 3 74 100 0 G
269 IgG1 2b 2.03e-11 1.43e-11 7.99e-09 5.32e-06 1.35e-11 5.46e-09 51.5 151.0 282.0 28.8 128.0 316.0 637.0 >25000 >25000 11 26 <0.32 14 2.82e+01 8.19e+01 1.53e+02 60.0 weak weak moderate weak weak moderate moderate 5.38 5.89 4.82 4.66 6.11 4.69 5.12 5.94 100.0 4.16 F486I 1.5mg/kg: 11318.93 45.00 1.46 7.36 9.68 0.52 5.15 3 7 637 5 90 95 83 H2
270 IgG1 2d 9.77e-12 5.85e-12 4.49e-11 1.97e-08 1e-09 4.85e-08 8.53 18.5 28.3 >25000 >25000 >25000 16.6 36.3 55.5 1 3 >25000 >25000 2.16e+01 5.10e+01 8.44e+01 0.0 strong strong moderate moderate weak moderate moderate 6.22 6.1 6.12 6.48 5.84 5.3 5.38 6.16 98.5 4.0 0.5mg/kg: 1401.83|1.5mg/kg: 4244.41 50.15 1.83 0.83 1.38 0.14 0.43 0 99 16.6 0 99 100 100 H3
271 IgG1 2d 1.7e-11 9.64e-12 1.12e-11 2.86e-09 1.51e-10 17.4 47.0 81.8 0.735 0.459 0.405 32.1 74.4 119.0 3 16 1624 3879 1.05e+02 1.50e+02 1.86e+02 30.0 strong strong strong strong weak moderate moderate 6.2 6.09 6.08 6.49 5.5 5.28 5.37 6.14 98.6 3.81 1.5mg/kg: 7760.50 48.45 1.77 0.73 1.21 0.09 0.28 0 94 32.1 0 98 92 100 H2
272 IgG1 2c 5.9e-11 4.42e-11 5.57e-09 4.63e-10 199.0 752.0 1360.0 >25000 >25000 >25000 71.5 213.0 401.0 40 116 24668 >25000 7.18e+02 1.62e+03 2.61e+03 strong moderate moderate moderate weak moderate moderate 6.08 6.01 5.66 6.38 5.42 5.21 5.31 6.05 97.2 1.3 38.55 1.41 0.85 1.41 0.24 0.72 5 92 71.5 2 92 100 98 H3
273 IgG1 6b 9.88e-11 8.88e-11 6.82e-10 5.22e-07 6.93e-11 21.8 83.7 170.0 62.8 154.0 249.0 21.8 52.1 86.2 4 15 9 24 1.26e+02 2.19e+02 3.03e+02 0.0 moderate weak weak moderate weak weak weak 4.77 6.02 4.09 4.42 4.49 3.72 4.79 5.91 100.0 0.859 1.5mg/kg: 2394.83 43.20 1.58 0.80 1.32 0.18 0.55 0 12 21.8 0 99 100 100 A
274 IgG1 6b 8.54e-11 4.45e-11 7.78e-10 4.99e-07 6.57e-11 21.7 70.1 126.0 61.3 142.0 226.0 18.8 56.5 101.0 4 13 9 29 9.48e+01 1.62e+02 2.22e+02 60.0 moderate weak weak moderate weak weak weak 4.75 6.04 4.14 4.3 4.6 3.57 4.86 5.89 100.0 1.56 0.5mg/kg: 2349.99|1.5mg/kg: 8943.40 41.75 1.53 0.77 1.27 0.16 0.48 1 1 18.8 1 100 96 90 A
275 IgG2b 2b 1.37e-10 9.76e-11 1.18e-08 1.34e-11 6.86 22.2 40.4 3.24 12.3 20.0 98.6 362.0 695.0 3 6 1 4 4.81e+01 6.79e+01 8.30e+01 80.0 moderate moderate moderate moderate moderate weak weak 5.94 6.09 6.44 4.07 5.49 5.35 5.38 6.13 100.0 1.02 1.5mg/kg: 50.30 40.65 1.49 0.80 1.31 0.19 0.57 0 2 98.6 27 100 97 100 H2
276 IgG2b 2b 4.65e-10 9.3e-11 3.49e-09 1.75e-06 1.31e-11 2.72 8.67 14.9 0.959 2.8 5.24 13.1 42.2 82.2 18 40 <0.32 2 5.70e+01 9.13e+01 1.20e+02 50.0 moderate moderate moderate strong moderate weak weak 5.98 6.17 6.8 4.02 5.57 5.33 5.39 6.12 100.0 1.02 1.5mg/kg: 50.30 35.85 1.31 1.72 2.83 0.47 1.39 0 1 13.1 1 100 99 100 H2
277 IgG2a 2d 2.45e-10 1.68e-10 4.59e-09 2.32e-06 9.6e-10 9.18 28.9 52.6 >25000 >25000 >25000 >25000 >25000 >25000 2 6 >25000 >25000 5.79e+01 9.13e+01 1.19e+02 moderate moderate strong strong weak weak weak 6.21 3.34 5.64 3.88 3.75 5.36 5.38 4.05 100.0 0.904 40.35 1.48 2.34 3.87 0.24 0.73 0 100 25000 100 100 100 100 H3
278 IgG1 4b 5.36e-10 6.89e-11 1.47e-09 2.93e-07 1.77e-11 11.7 44.4 96.6 22.6 90.7 195.0 >25000 >25000 >25000 5 16 2 20 8.91e+01 1.60e+02 2.26e+02 0.0 moderate weak strong strong weak weak weak 6.24 3.4 4.77 3.88 3.76 5.4 5.39 4.05 100.0 3.11 1.5mg/kg: 50.30 49.00 1.79 0.81 1.35 0.17 0.52 2 3 25000 100 100 100 81 G
279 IgG1 4b 1.01e-10 5.72e-11 6.65e-10 2.4e-07 2.32e-11 10.3 29.5 54.5 15.3 45.5 87.7 >25000 >25000 >25000 4 13 1 5 4.93e+01 1.25e+02 2.15e+02 10.0 moderate weak moderate strong weak weak weak 6.22 3.47 4.85 3.87 3.75 5.37 5.39 4.18 100.0 1.28 0.5mg/kg: 50.30|1.5mg/kg: 50.30|5mg/kg: 50.30 40.80 1.49 1.01 1.68 0.17 0.52 1 1 25000 100 2 6 2 G
280 IgG1 2b 1.27e-09 1.72e-09 7.66e-09 2.03e-06 1.44e-10 29.1 85.6 155.0 19.3 46.9 77.7 >25000 >25000 >25000 10 28 5 20 5.63e+01 1.11e+02 1.65e+02 0.0 moderate weak moderate strong weak weak weak 6.21 3.54 4.64 3.88 3.75 5.36 5.35 4.13 100.0 2.6 1.5mg/kg: 50.30 44.60 1.63 1.03 1.71 0.06 0.19 2 3 25000 100 100 97 100 H4
281 IgG2b 4b 3.77e-10 3.39e-10 8.59e-09 3.34e-06 3.72e-11 120.0 379.0 756.0 634.0 2590.0 10300.0 >25000 >25000 >25000 70 141 9 105 1.72e+02 4.49e+02 7.88e+02 10.0 weak strong moderate strong moderate weak weak 5.96 6.13 6.95 4.22 5.22 5.41 5.38 6.12 100.0 3.65 1.5mg/kg: 50.30 47.95 1.75 1.09 1.80 0.19 0.57 13 43 25000 100 80 24 26 G
282 IgG1 2d 5.5e-10 4.32e-10 8.24e-09 2.96e-06 7.85e-09 47.1 150.0 288.0 8.67 2690.0 9430.0 0.848 0.837 0.834 7 58 >25000 >25000 5.39e+01 1.39e+02 2.42e+02 moderate weak moderate weak weak weak weak 6.22 3.73 4.84 3.94 3.78 5.38 5.39 4.61 100.0 5.6 44.55 1.63 0.87 1.44 0.18 0.55 3 100 0.848 100 100 100 100 H3
283 IgG2a 6b 1.02e-10 1.31e-10 6.51e-10 2.08e-07 7.79e-11 103.0 312.0 544.0 331.0 693.0 1140.0 74.8 204.0 343.0 80 167 360 710 1.82e+02 6.46e+02 1.35e+03 30.0 moderate strong moderate moderate weak weak weak 5.62 6.05 5.19 3.86 3.75 5.28 5.39 6.13 93.4 1.67 1.5mg/kg: 50.30 39.20 1.43 1.01 1.68 0.23 0.69 10 38 74.8 10 100 100 99 A
284 IgG2a 6b 2.99e-10 2.34e-10 5.48e-10 7.5e-08 8.18e-11 134.0 473.0 823.0 370.0 783.0 1210.0 95.7 248.0 416.0 37 116 121 459 2.65e+02 4.91e+02 7.03e+02 50.0 moderate strong moderate moderate weak weak weak 6.03 6.1 5.46 3.82 3.75 5.28 5.38 6.12 95.0 1.15 1.5mg/kg: 50.30 35.30 1.29 1.18 1.95 0.16 0.48 17 47 95.7 15 100 100 99 A
285 IgG2a 2b 3.57e-10 4.88e-10 2.3e-08 1.14e-10 254.0 844.0 2190.0 508.0 >25000 >25000 148.0 430.0 1460.0 18 38 15 38 1.45e+02 3.93e+02 7.06e+02 40.0 moderate strong moderate strong moderate weak moderate 6.13 6.13 6.38 4.02 3.78 5.25 5.38 6.13 100.0 1.16 1.5mg/kg: 50.30 46.05 1.68 0.97 1.61 0.13 0.39 35 49 148 14 84 87 98 H2
286 IgG2a 3.99e-10 4.84e-10 1.1e-08 9.19e-11 >25000 >25000 >25000 1470.0 >25000 >25000 144 482 4.36e+03 8.25e+03 1.20e+04 0.0 strong moderate moderate moderate weak weak weak 6.08 6.14 5.8 3.87 3.79 5.27 5.39 6.14 100.0 1.63 1.5mg/kg: 50.30 41.35 1.51 0.91 1.50 0.23 0.67 75 100 1470 57 100 89 96 C3
287 IgG2a 7c 6.09e-10 6.51e-10 5.51e-10 6.35e-08 1.31e-10 712.0 9170.0 >25000 2150.0 7590.0 >25000 1250.0 2610.0 3160.0 121 333 3.72e+03 1.08e+04 2.02e+04 10.0 strong strong moderate moderate weak weak moderate 5.98 6.08 5.12 3.9 3.83 5.18 5.37 6.12 28.8 1.4 1.5mg/kg: 50.30 38.00 1.39 1.26 2.08 0.08 0.24 78 91 1250 79 100 100 100 C3
288 IgG1 2b 3.08e-11 1.56e-11 1.83e-08 1.98e-11 4.48e-09 34.5 102.0 188.0 20.3 70.7 139.0 13.3 31.2 50.9 17 63 3 16 4.00e+01 4.98e+02 2.17e+03 80.0 strong weak moderate strong weak moderate moderate 6.03 5.97 5.39 6.46 6.36 4.65 5.21 6.11 100.0 1.27 1.5mg/kg: 7793.19 42.00 1.54 1.05 1.74 0.20 0.60 2 10 13.3 2 100 100 100 H2
289 IgG1 2b 3.56e-11 2.21e-11 2.83e-09 1.85e-06 1.82e-11 1.28e-09 4.5 12.1 21.2 6.54 19.5 28.8 5.06 13.6 22.2 0.63 2 <0.32 2 1.71e+01 6.25e+01 1.33e+02 80.0 moderate moderate moderate moderate weak weak weak 5.66 6.11 4.62 6.24 6.41 5.06 5.33 6.19 100.0 0.975 1.5mg/kg: 6710.22 43.20 1.58 0.96 1.60 0.41 1.24 0 1 5.06 0 100 98 98 H2
290 IgG1 2b 2.49e-11 1.82e-11 3.26e-10 2.23e-07 1.63e-11 1.92e-09 5.73 13.0 20.4 3.46 10.3 17.2 1.84 6.91 11.2 1 3 <0.32 0.81 1.97e+01 4.13e+01 6.38e+01 10.0 strong strong strong strong weak moderate weak 6.2 6.1 6.15 6.45 5.6 5.28 5.37 6.14 100.0 2.94 5mg/kg: 43196.02 45.85 1.68 1.19 1.97 0.10 0.30 1 0 1.84 0 2 0 0 H2
291 IgG1 5a 3.67e-11 2.25e-11 6.83e-09 2.86e-06 2.4e-11 3.5e-10 2.74 5.69 8.04 2.25 5.82 9.57 >25000 >25000 >25000 <0.32 1 <0.32 0.51 1.93e+01 4.84e+01 8.29e+01 90.0 strong moderate moderate strong moderate moderate moderate 6.17 6.1 6.23 6.46 5.69 5.25 5.38 6.15 100.0 0.755 1.5mg/kg: 7254.11 38.00 1.39 0.96 1.59 0.15 0.46 0 0 25000 1 48 56 44 E1
292 IgG1 2b 1.9e-11 1.59e-11 6.71e-09 1.89e-06 2.6e-11 3.54e-09 5.22 13.3 22.7 7.99 28.3 59.6 0.844 3.88 6.18 1 3 3 18 2.27e+01 4.78e+01 7.40e+01 70.0 strong weak moderate moderate weak weak weak 6.14 6.08 6.45 6.46 5.76 5.33 5.37 6.13 100.0 2.59 1.5mg/kg: 6138.10 43.95 1.61 0.77 1.26 0.16 0.48 0 0 0.844 0 5 6 7 H2
293 IgG1 2b 1.8e-11 2.83e-11 4.29e-10 3.2e-07 5.76e-11 8.53e-09 3.16 11.3 23.3 11.8 46.7 101.0 2.67 9.21 14.2 <0.32 0.44 6 34 6.17e+01 9.73e+01 1.27e+02 20.0 strong moderate moderate strong moderate moderate weak 6.08 6.08 5.83 6.37 5.85 5.24 5.34 6.13 100.0 0.931 1.5mg/kg: 5656.25 39.00 1.43 1.29 2.13 0.19 0.57 1 2 2.67 2 34 27 38 H2
294 IgG1 2a 4.9e-11 2.2e-11 5.93e-11 2.34e-08 1.36e-10 1.3e-09 7.19 25.7 52.0 23.7 106.0 228.0 16.8 36.5 55.5 <0.32 7 31 108 1.07e+02 2.02e+02 2.93e+02 20.0 weak weak weak moderate weak weak weak 3.07 3.39 4.12 3.91 3.72 3.04 4.02 3.89 99.2 2.48 1.5mg/kg: 8561.64 41.40 1.51 1.09 1.80 0.15 0.46 1 1 16.8 1 2 2 0 H4
295 IgG1 4b 4.85e-11 3.02e-11 2.66e-10 1.48e-07 2.66e-11 1.62e-10 21.7 45.8 69.8 13.1 38.2 70.5 425.0 1590.0 >25000 3 7 <0.32 3 1.49e+02 3.32e+02 5.29e+02 30.0 moderate strong strong strong moderate weak moderate 6.19 6.11 6.54 6.48 5.84 5.38 5.39 6.19 78.0 0.818 1.5mg/kg: 6903.83 41.70 1.52 1.05 1.74 0.20 0.61 0 1 425 10 3 2 2 G
296 IgG1 2a 1.99e-10 5.09e-11 5.01e-10 2.26e-07 3.68e-10 5.25e-08 27.9 76.2 136.0 298.0 1030.0 1580.0 23.2 57.0 93.6 21 45 883 2607 3.07e+02 4.88e+02 6.40e+02 20.0 moderate moderate strong weak weak moderate weak 6.1 6.09 5.71 6.44 5.06 5.24 5.35 6.13 98.1 3.04 1.5mg/kg: 4867.01 47.25 1.73 0.94 1.55 0.10 0.30 100 97 23.2 100 100 100 91 H4
297 IgG1 2a 1.33e-10 4.2e-11 2.71e-10 4.48e-08 1.88e-10 5.22e-08 23.4 61.0 106.0 89.6 410.0 779.0 26.6 61.5 95.2 3 10 88 362 3.01e+02 5.29e+02 7.36e+02 10.0 strong strong strong weak weak weak weak 6.1 6.08 5.81 6.41 5.28 5.2 5.35 6.12 96.3 0.641 1.5mg/kg: 3367.14 39.80 1.46 0.85 1.40 0.36 1.09 2 13 26.6 4 99 69 100 H4
298 IgG1 5b 6.48e-10 2.08e-10 6.29e-10 3.75e-07 1.66e-10 4.51e-09 135.0 509.0 865.0 1070.0 >25000 >25000 162.0 494.0 873.0 266 589 7.30e+00 1.84e+01 3.15e+01 10.0 strong moderate strong weak moderate weak weak 6.17 6.11 5.59 6.41 5.26 5.26 5.37 6.19 100.0 3.08 1.5mg/kg: 4520.88 46.55 1.70 1.09 1.80 0.14 0.43 28 82 162 42 100 100 84 E4
299 IgG1 2a 9.55e-11 6.3e-11 3.32e-10 5.44e-08 3.84e-11 5.69e-09 33.2 75.5 125.0 10.2 38.0 77.2 37.2 89.5 142.0 16 34 2 15 1.66e+01 2.56e+01 3.30e+01 0.0 strong moderate strong weak weak weak weak 6.11 6.05 5.47 6.39 5.16 5.23 5.35 6.12 95.6 2.67 1.5mg/kg: 5342.70 52.10 1.90 6.61 10.93 3 1 37.2 5 7 2 4 H2
300 IgG1 2c 6.25e-11 2.79e-11 1.13e-09 2.31e-06 6.06e-09 5.2 14.3 24.3 >25000 >25000 >25000 38.3 94.3 158.0 <0.32 <0.32 >25000 >25000 2.59e+02 4.10e+02 5.35e+02 50.0 strong moderate strong weak moderate moderate weak 6.19 6.09 6.17 6.47 5.75 5.25 5.34 6.14 100.0 0.0836 1.5mg/kg: 10980.54 43.55 1.59 0.90 1.48 0.15 0.46 1 100 38.3 12 100 100 100 H3
301 IgG1 2a 8.45e-11 4.74e-11 1.55e-09 3.7e-07 6.78e-10 2.79e-07 15.6 52.1 92.2 >25000 >25000 >25000 29.5 60.9 90.6 5 21 <0.32 5 2.08e+02 6.60e+02 1.30e+03 10.0 strong moderate strong weak weak weak weak 6.05 6.08 6.34 6.43 5.52 5.29 5.35 6.14 100.0 2.08 1.5mg/kg: 6742.59 35.30 1.29 1.05 1.74 0.09 0.27 1 98 29.5 4 100 100 100 H4
302 IgG1 2a 4.99e-11 3.94e-11 4.16e-10 1.29e-07 4.55e-11 1.93e-08 41.5 168.0 345.0 68.3 268.0 558.0 64.6 165.0 290.0 23 82 29 111 5.28e+02 9.67e+02 1.38e+03 0.0 strong moderate strong moderate weak weak weak 5.93 5.97 5.05 6.27 4.76 5.07 5.26 6.05 97.9 1.13 1.5mg/kg: 2481.20 36.70 1.34 2.06 3.40 0.44 1.31 29 38 64.6 7 60 45 46 H4
303 IgG1 6a 3.75e-09 2.95e-09 1.77e-08 1.37e-09 8.96e-08 1750.0 >25000 >25000 >25000 >25000 >25000 3860.0 >25000 >25000 8853 >25000 2.50e+04 2.50e+04 2.50e+04 moderate weak weak moderate weak weak weak 4.85 5.36 4.08 4.32 3.76 3.73 4.42 5.59 100.0 0.924 99 88 3860 60 97 90 84 A
304 IgG1 4a 2.37e-10 1.23e-10 1.97e-07 1.22e-07 2.32e-10 1.03e-09 976.0 11300.0 >25000 >25000 >25000 >25000 0.0631 0.033 0.0276 42 461 >25000 >25000 2.40e+03 2.59e+04 1.04e+05 weak weak weak moderate weak weak moderate 3.1 3.37 4.11 3.84 3.7 3.03 4.06 3.94 100.0 1.12 40.85 1.49 1.02 1.69 0.23 0.67 50 93 0.0631 1 90 86 68 I
305 IgG1 5b 3.38e-09 1.58e-09 7.27e-09 1.69e-09 8.25e-09 2520.0 2580.0 2600.0 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 weak weak weak weak weak weak moderate 3.11 3.46 4.17 3.87 3.71 3.02 4.03 4.73 72.6 0.136 38.85 1.42 0.73 1.21 0.21 0.63 94 91 25000 13 86 100 81 E4
306 IgG1 2c 1.01e-09 5.36e-10 2.63e-08 3.83e-08 >25000 >25000 >25000 >25000 >25000 >25000 1593 3256 2.50e+04 2.50e+04 2.50e+04 weak weak weak weak weak moderate moderate 3.08 3.45 4.14 3.84 3.69 3.02 4.07 3.86 100.0 1.33 38.10 1.39 0.83 1.37 0.12 0.36 42 88 25000 11 100 90 85 B
307 IgG1 2b 2e-11 2.46e-11 2.36e-09 8.45e-07 8.95e-12 6.51e-09 5.83 14.3 23.9 9.67 38.7 92.2 122.0 594.0 1250.0 <0.32 3 <0.32 1 3.34e+01 5.10e+01 6.53e+01 60.0 strong strong strong weak weak moderate moderate 6.19 6.09 6.0 6.47 5.79 5.29 5.38 6.14 100.0 2.76 1.5mg/kg: 9720.63 47.15 1.72 2.03 3.36 0.01 0.01 1 3 122 11 97 93 90 H2
308 IgG1 4b 2.3e-11 2.83e-11 3.7e-10 1.39e-07 1.56e-11 5.41e-10 8.75 20.9 32.2 117.0 733.0 >25000 >25000 >25000 >25000 <0.32 <0.32 4 27 2.98e+01 4.23e+01 5.20e+01 70.0 moderate strong moderate weak weak moderate moderate 6.19 6.11 6.23 6.49 5.77 5.31 5.39 6.16 91.0 4.9 1.5mg/kg: 8929.00 48.10 1.76 1.54 2.55 0.01 0.03 1 27 25000 18 100 89 6 G
309 IgG1 6a 2.23e-11 3.25e-11 1.68e-10 8.44e-08 1.18e-10 2.12e-08 6.4 35.2 103.0 1700.0 20100.0 >25000 30.5 80.8 138.0 <0.32 7 683 1928 7.36e+01 1.27e+02 1.74e+02 moderate weak moderate weak weak strong strong 6.14 6.07 5.02 6.4 4.63 5.04 5.34 6.13 99.3 3.08 47.95 1.75 1.20 1.98 0.18 0.55 1 66 30.5 2 100 97 86 B
310 IgG1 2b 2.19e-11 3.97e-11 1.85e-09 1.57e-06 1.21e-11 1.12e-08 3.39 8.94 13.9 9.31 43.6 101.0 601.0 2450.0 3820.0 <0.32 <0.32 0.32 5 3.31e+01 4.29e+01 4.99e+01 10.0 moderate moderate strong weak moderate strong strong 6.16 6.11 6.44 6.45 5.46 5.18 5.37 6.19 100.0 4.77 1.5mg/kg: 5169.00 48.85 1.79 1.08 1.79 0.12 0.37 2 4 601 46 100 86 91 H2
311 IgG1 2b 5.78e-11 5.7e-11 3.03e-09 1.76e-11 2.21e-08 3.39 9.17 16.6 54.2 221.0 488.0 3000.0 5700.0 6620.0 <0.32 2 14 61 1.83e+01 2.54e+01 3.08e+01 20.0 moderate moderate strong weak moderate strong strong 6.18 6.1 5.95 6.43 5.52 5.24 5.37 6.24 94.2 2.45 1.5mg/kg: 3885.39 42.60 1.56 0.74 1.22 0.13 0.39 1 4 3000 86 100 100 91 H2
312 IgG1 4b 3.28e-11 4.1e-11 3.47e-10 2.02e-07 2.09e-11 7.84e-10 2.73 6.42 8.99 3.37 7.69 12.7 49.9 212.0 497.0 <0.32 <0.32 <0.32 <0.32 1.10e+01 1.27e+01 1.38e+01 0.0 moderate moderate moderate moderate moderate strong strong 6.12 6.09 6.18 6.46 5.55 5.31 5.37 6.15 100.0 3.03 1.5mg/kg: 7230.67 45.00 1.65 0.85 1.41 0.16 0.48 1 0 49.9 7 61 100 12 H2
313 IgG1 4b 3.01e-11 3.62e-11 1.55e-10 1.21e-07 2.83e-11 7.29e-10 3.62 8.78 12.2 2.52 7.22 12.8 53.2 162.0 316.0 <0.32 <0.32 <0.32 <0.32 9.58e+00 1.10e+01 1.19e+01 20.0 strong moderate moderate strong moderate strong strong 6.17 6.11 6.34 6.47 5.7 5.37 5.38 6.17 100.0 1.86 0.5mg/kg: 774.42|1.5mg/kg: 4277.45 37.25 1.37 0.81 1.07 0.94 0.84 1 0 53.2 6 42 100 3 H2
314 IgG1 7a 1.29e-10 2.03e-10 2.28e-08 5.7e-11 4.06e-09 2.16 11.8 21.5 1.85 7.04 14.7 1.54 4.17 6.35 <0.32 3 <0.32 5 4.77e+01 5.55e+01 6.07e+01 0.0 moderate weak weak strong moderate moderate moderate 5.91 6.01 4.68 6.14 4.04 5.04 5.29 6.09 100.0 3.24 1.5mg/kg: 50.30 46.45 1.71 0.64 0.85 0.73 0.66 1 0 1.54 1 1 0 96 C1
315 IgG1 7a 5.58e-10 1.58e-10 4.45e-08 4.89e-11 1.39e-08 0.429 3.44 7.53 1.05 3.75 8.21 0.677 1.7 3.13 <0.32 <0.32 <0.32 3 3.27e+01 5.03e+01 6.47e+01 moderate moderate weak weak moderate weak weak 5.76 5.94 4.15 6.03 3.86 4.62 5.08 6.03 99.1 2.38 37.00 1.37 0.73 0.98 0.66 0.59 2 0 0.677 0 0 1 78 C1
316 IgG1 7a 5.53e-11 1.57e-10 3.41e-08 8.85e-11 1.45e-09 0.802 4.24 10.2 0.334 1.61 3.02 <0.32 <0.32 2 4 1.56e+01 2.91e+01 4.19e+01 moderate moderate weak strong moderate moderate moderate 5.74 5.91 4.11 6.02 3.77 4.49 5.01 5.98 99.2 2.61 44.50 1.64 0.97 1.30 0.50 0.45 1 0 0.334 0 2 1 73 C1
317 IgG1 7a 1.4e-10 4.31e-10 4.13e-08 7.21e-11 1.77e-08 0.518 2.58 5.74 0.949 4.99 11.7 0.672 1.86 3.72 <0.32 <0.32 <0.32 4 2.78e+01 4.40e+01 5.74e+01 moderate weak weak moderate weak moderate moderate 4.72 5.68 4.09 3.95 3.75 3.07 4.16 5.92 94.1 2.27 39.70 1.46 0.83 1.11 0.94 0.84 1 0 0.672 1 0 1 75 C1
318 IgG1 7a 5.05e-09 5.47e-10 5.87e-08 2.11e-10 6.92e-08 97.7 485.0 1960.0 57.4 194.0 365.0 350.0 2100.0 >25000 42 120 48 120 7.18e+02 1.22e+03 1.66e+03 moderate moderate moderate weak weak moderate moderate 5.69 5.95 4.11 6.32 3.74 4.23 4.97 6.04 92.8 1.75 10 1 350 2 27 13 73 A
319 IgG1 7a 4.86e-10 7.16e-10 3.09e-08 5.39e-11 1.93e-08 6.75 30.0 59.7 3.42 13.2 27.7 35.0 59.9 102.0 4 21 11 32 3.27e+02 4.42e+02 5.27e+02 strong moderate weak weak weak strong strong 5.85 5.92 4.16 6.28 3.81 4.07 4.98 6.0 99.4 1.96 39.05 1.44 0.88 1.17 0.78 0.70 2 0 35 0 1 1 91 B
320 IgG1 7a 1.76e-10 5.23e-10 3.07e-08 1.13e-10 4.47e-09 2.03 11.0 19.2 2.64 7.81 14.4 12.2 20.7 31.6 1 16 15 29 5.46e+01 6.58e+01 7.33e+01 0.0 strong moderate moderate weak weak strong strong 5.99 6.0 4.9 6.32 4.28 5.02 5.32 6.07 100.0 3.5 1.5mg/kg: 50.30 43.80 1.62 0.59 0.79 0.54 0.48 1 0 12.2 0 3 1 77 C1
321 IgG1 7a 1.79e-10 6.5e-10 3e-08 9.51e-11 3.93e-09 3.34 11.6 22.1 2.59 9.26 18.7 10.1 13.4 16.4 3 11 16 34 5.52e+01 8.78e+01 1.15e+02 moderate weak weak weak weak moderate moderate 5.39 5.84 4.14 4.55 3.85 3.72 4.74 6.05 100.0 2.02 0.5mg/kg: 50.30 39.55 1.46 0.43 0.57 0.54 0.48 1 0 10.1 0 1 1 1 C1
322 IgG1 7a 1.32e-10 6.64e-10 3.02e-08 4.5e-11 5.09e-09 5.18 24.2 54.8 4.89 15.5 28.2 6.92 22.3 43.5 13 47 19 69 7.11e+01 1.13e+02 1.48e+02 moderate moderate weak weak weak moderate moderate 5.54 5.89 4.18 4.53 3.83 3.87 4.8 6.06 100.0 3.31 44.85 1.65 0.69 0.92 0.60 0.54 3 0 6.92 0 3 1 49 C1
323 IgG1 4c 7.91e-11 4.88e-11 2.5e-09 1.07e-06 2.41e-11 2.56e-10 61.0 319.0 816.0 40.9 259.0 622.0 >25000 >25000 >25000 41 253 1 6 7.33e+02 2.66e+03 5.66e+03 0.0 moderate moderate moderate moderate weak moderate moderate 6.31 6.2 5.84 6.2 5.27 5.41 5.43 6.23 94.9 2.66 1.5mg/kg: 10493.43|5mg/kg: 50117.28 43.35 1.60 0.65 0.87 0.68 0.61 32 12 25000 100 30 95 6 G
324 IgG1 4c 7.34e-10 6.49e-10 1.13e-08 1.78e-10 7.02e-09 >25000 >25000 >25000 17500.0 >25000 >25000 10448 19929 2.50e+04 2.50e+04 2.50e+04 0.0 moderate moderate weak moderate weak weak weak 6.14 6.1 5.14 6.01 4.61 5.22 5.36 6.13 100.0 2.5 5mg/kg: 3822.42 37.35 1.38 0.87 1.16 0.57 0.51 100 97 17500 100 100 100 4 G
325 IgG1 2a 1.99e-10 7.69e-11 4.19e-09 2.51e-10 7.5e-09 1410.0 5500.0 9140.0 >25000 >25000 >25000 610.0 3690.0 6820.0 203 1423 4.45e+03 7.63e+03 1.05e+04 moderate moderate weak strong weak weak moderate 6.16 6.08 5.73 6.07 5.05 5.27 5.38 6.12 100.0 1.86 38.70 1.43 1.18 1.57 1.15 1.02 66 100 610 35 100 100 92 B
326 IgG1 2c 3.25e-10 8.29e-11 1.77e-07 5.96e-10 1.08e-09 350.0 1120.0 1710.0 >25000 >25000 >25000 7.02 20.5 38.7 12 71 1816 4617 1.21e+03 1.79e+03 2.26e+03 60.0 moderate weak moderate moderate weak moderate strong 6.19 6.13 5.61 6.06 5.15 5.35 5.42 6.19 100.0 1.49 5mg/kg: 23384.78 35.05 1.29 1.24 1.65 0.72 0.65 26 90 7.02 0 16 15 23 H2
327 IgG1 5b 1.04e-09 1.18e-09 2.3e-07 1.15e-09 4.17e-09 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 moderate moderate weak moderate weak strong weak 6.02 6.07 5.79 5.85 3.9 4.98 5.31 6.14 57.3 1.63 34.75 1.28 0.89 1.19 0.97 0.87 99 93 25000 62 96 88 78 E4
328 IgG1 5b 6.58e-10 6.76e-10 9.87e-08 7.06e-10 7.18e-09 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 moderate weak weak moderate weak weak weak 6.16 6.13 4.83 5.99 4.19 5.29 5.37 6.19 54.9 2.16 43.30 1.60 0.66 0.87 0.54 0.48 96 97 25000 55 91 87 82 E4
329 IgG1 5.91e-09 3.45e-09 4.45e-09 4.11e-09 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 moderate weak weak weak weak weak moderate 4.79 4.96 4.36 4.1 3.78 3.71 4.44 5.35 9.8 0.605 34.75 1.28 1.15 1.53 0.49 0.44 92 95 25000 58 90 88 75 E3
330 IgG1 7a 1.4e-09 1.88e-09 6.1e-07 1.49e-09 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 weak moderate weak weak weak weak moderate 5.56 5.9 4.37 5.36 3.79 4.64 5.12 6.01 82.9 1.22 32.95 1.22 1.06 1.41 0.62 0.56 96 89 25000 94 96 85 70 C3
331 IgG1 2a 5.95e-11 2.58e-11 7.04e-11 4.05e-08 4.4e-11 2.65e-08 12.5 42.2 81.2 17.2 65.9 130.0 20.2 75.3 150.0 16 44 8 22 8.81e+01 1.32e+02 1.68e+02 0.0 strong moderate moderate weak weak weak weak 6.29 6.16 5.55 6.19 5.14 5.37 5.41 6.21 91.8 1.17 1.5mg/kg: 9781.65 35.60 1.31 0.90 1.20 0.61 0.54 1 1 20.2 3 77 70 48 H4
332 IgG1 2a 2.34e-11 1.04e-11 1.11e-10 7.69e-08 3.26e-11 4.84 18.7 38.5 25.9 82.0 272.0 13.1 40.5 71.4 1 3 <0.32 2 1.75e+01 3.75e+01 5.85e+01 60.0 strong moderate moderate weak weak weak moderate 6.27 6.19 5.62 6.21 5.53 5.39 5.43 6.23 99.3 2.24 1.5mg/kg: 11249.88 38.00 1.40 0.72 0.96 0.73 0.66 1 6 13.1 1 94 90 95 H2
333 IgG1 2b 1.24e-11 6.4e-12 1.11e-11 1.77e-08 1.52e-11 1.93e-11 4.0 10.3 17.6 3.14 8.88 17.0 3.92 11.7 21.6 <0.32 <0.32 <0.32 <0.32 1.12e+01 1.32e+01 1.46e+01 80.0 strong moderate strong moderate weak weak moderate 6.37 6.22 5.99 6.27 5.64 5.39 5.45 6.24 97.4 0.774 1.5mg/kg: 9583.62 35.15 1.30 0.67 0.89 0.66 0.59 0 0 3.92 0 1 1 0 H2
334 IgG1 2b 1.51e-11 7.39e-12 5.68e-11 3.6e-08 8.67e-12 7.71e-11 3.72 11.0 19.3 2.23 5.34 9.03 3.7 9.19 13.3 <0.32 <0.32 <0.32 2.42e+01 3.83e+01 5.01e+01 90.0 strong strong strong moderate weak weak moderate 6.3 6.19 6.17 6.22 5.6 5.38 5.43 6.23 100.0 2.84 1.5mg/kg: 12203.69 49.00 1.81 1.20 1.60 0.78 0.70 1 0 3.7 0 5 6 4 H2
335 IgG1 5a 1.64e-10 2.4e-11 9e-09 3.05e-06 1.78e-11 1.2e-08 6.94 19.8 35.4 7.78 23.2 44.7 6.41 19.7 36.1 <0.32 1 <0.32 <0.32 6.29e+01 1.41e+02 2.27e+02 100.0 strong moderate moderate moderate weak moderate moderate 6.3 6.23 6.33 6.27 5.7 5.39 5.45 6.24 100.0 2.31 1.5mg/kg: 6860.78 41.00 1.51 1.30 1.74 1.39 1.24 1 2 6.41 1 100 99 80 G
336 IgG1 5d 3.73e-11 1.15e-11 2.14e-09 7.68e-07 1.04e-11 9.27e-10 2.94 6.58 11.5 2.14 6.03 9.59 1.07 4.12 9.13 <0.32 1 <0.32 1 2.16e+01 3.53e+01 4.71e+01 70.0 strong moderate strong moderate weak moderate moderate 6.33 6.21 6.21 6.24 5.81 5.45 5.45 6.25 100.0 1.83 1.5mg/kg: 4844.32 42.00 1.55 1.15 1.53 0.46 0.41 1 1 1.07 0 100 93 1 G
337 IgG1 4b 2.81e-11 7.33e-12 3.02e-09 1.21e-06 1.23e-11 5.74e-09 6.16 17.1 31.0 16.7 65.1 152.0 >25000 >25000 >25000 <0.32 <0.32 <0.32 <0.32 6.94e+01 1.16e+02 1.57e+02 100.0 strong moderate moderate moderate weak weak weak 6.33 6.21 6.49 6.27 5.75 5.41 5.45 6.24 100.0 1.2 1.5mg/kg: 9485.93 37.95 1.40 0.73 0.98 0.57 0.51 1 10 25000 43 100 100 11 G
338 IgG1 4c 2.36e-11 1.35e-11 6.64e-12 3.1e-09 4.37e-11 4.89e-10 10.9 42.9 89.0 69.8 >25000 >25000 83.3 285.0 703.0 <0.32 9 12 63 9.20e+01 6.51e+02 2.05e+03 10.0 strong weak strong strong weak weak weak 6.27 6.18 5.75 6.08 5.53 5.44 5.43 6.24 74.9 1.0 1.5mg/kg: 8664.69 36.10 1.33 0.84 1.13 1.33 1.19 3 38 83.3 4 33 56 14 G
339 IgG1 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 30.0 weak weak moderate moderate weak strong strong 4.17 4.13 4.41 3.76 3.8 3.67 5.3 4.66 11.5 1.06 1.5mg/kg: 50.30 38.05 1.40 1.94 2.58 1.50 1.34 95 92 25000 85 100 96 78
340 IgG1 1.56e-08 555.0 1790.0 2480.0 73.7 579.0 1040.0 >25000 >25000 >25000 23910 >25000 2.50e+04 2.50e+04 2.50e+04 0.0 weak weak moderate strong weak strong strong 4.23 4.1 4.53 3.75 3.78 3.64 4.4 4.56 1.4 0.941 1.5mg/kg: 50.30|5mg/kg: 50.30 32.85 1.21 1.25 1.66 0.52 0.46 100 88 25000 77 95 82 76
341 IgG1 >25000 >25000 >25000 >25000 >25000 >25000 18581 >25000 2.50e+04 2.50e+04 2.50e+04 0.0 weak weak moderate moderate weak moderate moderate 4.31 4.35 4.3 3.76 3.78 3.64 4.4 4.78 2.8 0.542 1.5mg/kg: 50.30|5mg/kg: 50.30 32.75 1.21 0.93 1.23 0.56 0.50 100 89 25000 87 100 85 60
342 IgG1 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 0.0 weak weak weak moderate weak moderate moderate 4.04 3.92 4.33 3.71 3.8 3.63 4.4 4.44 23.5 0.608 1.5mg/kg: 50.30|5mg/kg: 50.30 32.90 1.21 1.59 2.13 1.41 1.26 89 88 25000 87 96 79 68
343 IgG1 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 10.0 weak weak weak weak weak weak weak 4.04 3.92 4.36 3.73 3.8 3.57 4.37 4.38 0.522 1.5mg/kg: 50.30|5mg/kg: 50.30 39.10 1.44 1.03 1.37 0.44 0.39 100 92 25000 86 100 93 74
344 IgG1 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 0.0 weak moderate weak weak weak weak moderate 4.05 3.86 4.33 3.75 3.79 3.59 4.39 4.31 1.5 0.688 1.5mg/kg: 50.30|5mg/kg: 50.30 45.25 1.67 0.88 1.17 0.56 0.50 100 85 25000 87 99 78 69
345 IgG1 3.98e-11 1.81e-11 1.77e-09 2.1e-08 >25000 >25000 >25000 >25000 >25000 >25000 <0.32 <0.32 >25000 >25000 8.26e+01 2.36e+02 4.38e+02 strong weak weak moderate weak weak moderate 6.24 6.13 5.47 6.15 5.4 5.18 5.4 6.17 4.7 0.678 42.05 1.55 0.77 1.03 1.26 1.12 41 97 25000 76 62 96 74 E2
346 IgG1 3.12e-11 1.44e-11 2.1e-09 2.38e-11 63.3 453.0 935.0 278.0 940.0 1600.0 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 8.4 56 72 25000 78 98 100 78 E3
347 IgG1 9.76e-10 6.76e-10 5.49e-09 3.28e-10 4.25e-09 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 10.2 100 97 25000 96 100 88 75 C2
348 IgG1 >25000 >25000 >25000 >25000 >25000 >25000 100 100 25000 100 100 100 95
349 IgG1 2.84e-09 1.04e-09 1.26e-07 29.0 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 1 5 >25000 >25000 1.42e+02 3.45e+02 5.82e+02 moderate moderate weak moderate weak weak moderate 5.95 5.92 4.55 5.75 4.19 4.84 5.22 6.01 29.1 0.749 40.10 1.48 0.90 1.19 1.04 0.93 42 100 25000 100 100 100 91 E2
350 IgG1 1.73e-09 9.89e-10 2.32e-08 3.29e-08 250.0 >25000 >25000 928.0 >25000 >25000 >25000 >25000 >25000 20 88 9099 18089 3.42e+02 2.09e+03 6.04e+03 moderate strong moderate moderate weak weak moderate 5.32 5.61 4.34 4.71 3.92 3.87 4.62 5.77 29.4 0.654 42.15 1.56 0.81 1.09 0.69 0.62 40 96 25000 92 100 91 90 E3
351 IgG1 2d 4.42e-11 1.05e-11 6.96e-09 3.22e-06 4.62 11.8 19.7 >25000 >25000 >25000 >25000 >25000 >25000 <0.32 <0.32 4.54e+01 5.29e+01 5.78e+01 90.0 strong moderate strong weak weak weak weak 6.33 6.2 6.5 6.28 5.77 5.45 5.46 6.25 100.0 0.366 1.5mg/kg: 10845.63 45.70 1.69 0.69 0.92 0.72 0.64 1 95 25000 84 100 97 82 H3
352 IgG1 2d 1.69e-11 9e-12 1.95e-08 11.4 44.3 89.3 >25000 >25000 >25000 >25000 >25000 >25000 <0.32 <0.32 8.40e+01 1.57e+02 2.27e+02 90.0 100.0 0.81 1.5mg/kg: 14084.70 24.25 1.13 0.24 0.79 0.06 0.83 3 99 25000 97 100 88 73 H3
353 IgG1 2d 7.85e-11 2.08e-11 1.39e-08 5.31e-06 24.4 57.6 83.0 >25000 >25000 >25000 >25000 >25000 >25000 <0.32 <0.32 1.81e+02 2.06e+02 2.22e+02 strong strong moderate moderate weak weak weak 6.26 6.2 6.24 6.14 5.75 5.45 5.45 6.24 100.0 0.954 23.10 1.08 0.18 0.61 0.10 1.50 4 96 25000 96 100 86 83 H3
354 IgG 2b 4.89e-11 1.78e-11 5.1e-10 2e-07 1.13e-11 8.5e-10 21.2 81.1 163.0 15.3 83.1 203.0 33.4 126.0 262.0 <0.32 1 7.36e+01 9.81e+01 1.16e+02 20.0 strong moderate strong moderate weak strong weak 6.28 6.19 5.65 6.17 5.4 5.42 5.46 6.25 100.0 0.818 1.5mg/kg: 10050.93 23.95 1.12 0.30 1.00 0.10 1.46 1 2 33.4 2 13 17 20 H2
355 IgG1 5d 8.13e-11 2.15e-11 1.25e-08 5.15e-06 1.72e-11 2.62e-10 4.97 18.7 39.8 3.25 11.3 22.9 1.87 36.4 90.3 3.85e+01 7.50e+01 1.11e+02 100.0 100.0 1.5mg/kg: 6120.14 22.90 1.07 0.40 1.30 0.12 1.85 3 1 1.87 2 84 69 10 G
356 IgG1 2b 4.55e-11 1.22e-11 1.06e-08 4.29e-06 3.02e-10 1.25e-08 6.12 52.2 123.0 2250.0 19800.0 >25000 44.1 279.0 793.0 9.06e+01 2.16e+02 3.59e+02 100.0 100.0 1.5mg/kg: 13940.55 21.25 0.99 0.28 0.93 0.02 0.36 1 86 44.1 12 100 93 72 H2
357 IgG1 2a 1.39e-10 4.26e-11 1.74e-08 5.15e-06 3.42e-09 8.2e-08 39.6 140.0 264.0 >25000 >25000 >25000 8.86 9.3 9.75 1.63e+02 6.41e+02 1.43e+03 80.0 100.0 1.5mg/kg: 9425.66 28.95 1.35 0.09 0.29 0.32 4.81 4 97 8.86 0 100 93 77 H4
358 IgG1 4.94e-10 1.94e-10 6.57e-08 4.7e-08 1740.0 >25000 >25000 >25000 >25000 >25000 2170.0 6080.0 7920.0 2.50e+04 2.50e+04 2.50e+04 0.0 1.5mg/kg: 602.05 27.90 1.30 0.17 0.57 0.20 3.01 79 72 2170 99 100 81 78 E2
359 IgG1 2a 3.6e-11 1.77e-11 1.39e-11 4.86e-09 6.13e-11 1.33e-09 9.03 21.2 34.4 17.7 57.1 120.0 17.0 38.7 61.6 6.88e+01 1.34e+02 1.97e+02 30.0 95.1 1.5mg/kg: 6131.03 21.50 1.00 0.24 0.79 0.09 1.28 1 4 17 0 11 5 2 H2
360 IgG1 2a 5.29e-11 1.68e-11 1.32e-11 8.06e-09 1.15e-11 2.31e-10 7.22 22.1 39.7 2.8 7.46 12.6 16.8 34.1 50.3 6.76e+01 1.42e+02 2.19e+02 50.0 97.2 1.5mg/kg: 7398.47 23.40 1.09 0.23 0.75 0.08 1.23 2 0 16.8 2 2 5 4 H2
361 IgG1 2a 1.1e-10 2.95e-11 2.41e-11 1.25e-08 1.86e-11 3e-10 12.3 42.5 83.6 5.28 17.7 35.6 19.2 51.3 91.5 5.76e+01 1.80e+02 3.50e+02 30.0 94.9 1.5mg/kg: 6513.45 22.80 1.06 0.28 0.93 0.06 0.90 2 1 19.2 3 4 2 2 H2
362 IgG1 2a 3.29e-11 9.64e-12 9.85e-12 4.3e-09 1.15e-11 2.1e-10 6.45 18.8 34.5 1.6 5.97 11.3 14.3 29.1 42.8 3.51e+01 6.43e+01 9.18e+01 20.0 96.4 1.5mg/kg: 10972.59 23.25 1.08 0.29 0.97 0.16 2.41 1 0 14.3 2 1 1 0 H2
363 IgG1 5.77e-10 5.62e-10 2.87e-09 9.03e-10 3.91e-09 >25000 >25000 >25000 >25000 >25000 >25000 2.50e+04 2.50e+04 2.50e+04 10.0 1.5mg/kg: 857.23 22.85 1.07 0.27 0.87 0.07 1.13 100 73 25000 100 100 90 86 E3
364 IgG1 1.75e-09 7.51e-10 1.97e-08 3.27e-10 2.38e-10 27.5 77.0 145.0 60.5 217.0 411.0 >25000 >25000 >25000 2.80e+02 7.50e+02 1.33e+03 90.0 1.5mg/kg: 256.70 21.50 1.00 0.30 1.00 0.10 1.50 8 10 25000 100 7 7 65 E3
365 IgG1 2.2e-11 1.14e-11 3.02e-10 1.56e-10 11.1 >25000 >25000 >25000 >25000 >25000 >25000 >25000 >25000 2.69e+01 7.46e+01 1.36e+02 60.0 1.5mg/kg: 2297.93 21.20 0.99 0.33 1.08 0.06 0.83 30 82 25000 42 100 93 22 E2
366 IgG1 7b 1.09e-10 9.51e-11 7.03e-11 4.02e-08 5.33e-11 1.28e-08 200.0 818.0 2210.0 232.0 693.0 915.0 210.0 627.0 867.0 1.24e+03 1.89e+03 2.42e+03 0.0 81.7 1.5mg/kg: 6151.03 22.80 1.06 0.26 0.84 0.12 1.80 35 40 210 15 100 85 76 C3
367 IgG1 4c 7.01e-11 1.54e-11 3.01e-11 1.82e-08 1.04e-10 8.64e-10 35.3 127.0 332.0 >25000 >25000 >25000 312.0 2530.0 >25000 3.46e+02 1.22e+03 2.54e+03 70.0 45.3 1.5mg/kg: 8775.66 21.65 1.01 0.29 0.97 0.05 0.71 7 69 312 36 66 73 32 G
368 IgG1 3b 2.71e-11 1.45e-11 4.36e-10 1.98e-07 1.12e-11 2.08e-10 3.6 10.7 18.1 2.69 7.77 13.5 2.26 7.47 14.9 3.49e+01 6.33e+01 8.98e+01 70.0 100.0 1.5mg/kg: 5925.57 23.30 1.09 0.24 0.79 0.10 1.58 1 0 2.26 0 0 2 0 A
369 IgG1 2a 7.51e-10 1.66e-10 2.09e-10 3.1e-08 4.29e-11 7.64e-09 157.0 498.0 868.0 18.1 65.7 125.0 91.2 345.0 610.0 1.48e+03 2.47e+03 3.34e+03 0.0 79.0 1.5mg/kg: 2943.18 26.80 1.25 0.11 0.36 0.41 6.09 24 4 91.2 19 35 17 34 B
370 IgG1 4a 2.24e-11 2.67e-11 1.16e-10 6.56e-08 1.17e-10 1.33e-08 1.33e+01 1.56e+01 1.70e+01 10.0 99.6 1.5mg/kg: 20815.20 26.30 1.23 0.02 0.07 0.14 2.11 1 16 nt 10 17 20 22 H2
371 IgG1 4a 4.5e-11 3.24e-11 1.17e-09 3.36e-07 2.24e-11 1.94e-10 1.64e+01 2.32e+01 2.83e+01 0.0 100.0 1.5mg/kg: 7301.76|5mg/kg: 4452.89 24.45 1.14 0.24 0.80 0.07 0.98 0 1 nt 1 1 2 1 H3
372 IgG1 3.36e-11 8.24e-11 9.16e-11 9.52e-08 8.46e-11 3.91e-10 2.84e+03 1.67e+04 4.71e+04 0.0 86.8 1.5mg/kg: 8461.38 17 40 nt 27 100 49 79 A
373 IgG1 3.06e-11 7.94e-11 5.89e-11 5.81e-08 6.92e-11 5.62e-10 2.54e+03 1.10e+04 2.61e+04 0.0 89.0 1.5mg/kg: 7693.29 16 35 nt 20 72 59 86 A
374 IgG1 7.83e+00 1.18e+01 1.50e+01
375 IgG1 7.41e+00 1.67e+01 2.68e+01 60.0 1.5mg/kg: 9131.97
376 IgG1 9.23e+00 1.69e+01 2.42e+01
377 IgG1 6.19e+00 3.21e+01 8.43e+01
378 IgG1 1.67e+01 6.21e+01 1.34e+02
379 IgG1 1.02e+01 2.21e+01 3.49e+01
380 IgG1 9.69e+00 3.95e+01 9.00e+01 50.0 1.5mg/kg: 7762.41
381 IgG1 3.53e+00 1.84e+01 4.84e+01
382 IgG1 8.08e+00 2.15e+01 3.82e+01
383 IgG1 9.45e+00 2.42e+01 4.19e+01
384 IgG1 6.68e-11 2.79e-10 2.84e-10 1.92e-10 2.84e+03 2.47e+04 8.77e+04 10.0 1.5mg/kg: 8284.68 92 99 nt 100 100 89 100 E3
385 IgG1 2.47e-11 2.93e-11 3.27e-11 2.21e-08 1.88e-11 3.45e-11 6.35e+01 9.62e+01 1.23e+02 10.0 98.2 1.5mg/kg: 5621.77 1 0 nt 0 1 0 0 H2
386 IgG1 2.71e-11 3.47e-11 1.77e-10 9.15e-08 1.96e-11 4.33e-10 3.28e+01 6.63e+01 1.00e+02 0.0 99.4 1.5mg/kg: 6160.13 0 0 nt 1 0 1 0 G
387 IgG 7.79e-10 1.33e-09 2.32e-09 5.58e-09 2.50e+04 2.50e+04 2.50e+04 0.0 3.3 1.5mg/kg: 50.30 92 90 nt 100 95 91 87 E3
388 IgG 9.63e-10 3.96e-09 3.75e-09 1.04e-08 2.50e+04 2.50e+04 2.50e+04 0.0 11.1 1.5mg/kg: 50.30 98 92 nt 100 88 88 87 E3
389 IgG 2.8e-09 2.50e+04 2.50e+04 2.50e+04 10.0 1.5mg/kg: 50.30 94 86 nt 100 74 88 83 E3
390 IgG 6e-10 8.67e-10 1.3e-09 2.50e+04 2.50e+04 2.50e+04 3.4 100 93 nt 100 100 88 87 E3
391 IgG 6.3e-11 1.44e-10 1.98e-11 9.23e-09 2.1e-10 8.47e-10 1.52e+03 4.87e+03 9.65e+03 80.0 4.0 1.5mg/kg: 10918.63 38 69 nt 93 65 64 61 G
392 IgG1 2.3e-11 3.41e-11 8.71e-11 1.85e-08 2.1e-11 1.01e-10 2.63e+01 6.56e+01 1.12e+02 0.0 95.2 1.5mg/kg: 12855.33 1 2 nt 1 4 8 14 H2
393 IgG1 2.8e-11 3.24e-11 2.33e-10 9.01e-08 2.82e-11 2.64e-10 3.51e+01 8.04e+01 1.31e+02 30.0 99.0 1.5mg/kg: 12002.49 1 1 nt 1 1 1 1 G
394 IgG1 1.18e-10 2.82e-10 1.44e-08 2.15e-11 4.55e-09 2.99e+02 5.18e+02 7.15e+02 100.0 1 1 nt 0 50 100 40 H4
395 IgG1 9.01e-11 2.14e-10 1.67e-08 2.9e-11 1.22e-09 2.75e+02 5.11e+02 7.35e+02 100.0 1 6 nt 0 21 14 24 H4
396 IgG1 2.12e-11 7.66e-11 2.83e-11 4.7e-09 3.24e-11 8.46e-10 1.63e+04 3.47e+04 5.39e+04 36.4 93 94 nt 95 94 90 88
397 IgG1 6.97e-12 8.74e-12 6.51e-11 3.36e-08 1.38e-11 1.07e-10 1.39e+01 2.14e+01 2.75e+01 99.2
398 IgG1 1.16e-11 3.97e-11 4.7e-11 2.84e-10 1.04e+04 1.82e+04 2.52e+04 6.9
399 IgG1 1.11e-10 4.47e-10 2.4e-10 2.05e-09 2.50e+04 2.87e+04 6.14e+04 10.6
400 IgG1 1.56e-10 4.62e-10 6.21e-10 2.73e-09 2.50e+04 2.13e+02 2.25e+02
401 IgG1 1.04e-11 4.14e-11 5.18e-11 3.37e-10 2.50e+04 2.10e+01 2.07e+01 16.2
402 IgG1 1.07e-11 2.93e-11 5.09e-11 2.27e-08 6.45e-11 2.69e-10 2.16e+02 1.57e+03 5.01e+03 7.4
403 IgG1 8.06e-12 9.8e-12 9.72e-11 4.15e-08 7.42e-12 1.58e-09 1.04e+01 2.72e+01 4.78e+01 100.0
404 IgG1 1.23e-11 1.68e-11 2.1e-10 7.94e-08 1.53e-11 1.88e-08 1.55e+01 2.21e+01 2.71e+01 99.2
405 IgG1 4.91e-11 2.46e-11 8.83e-10 5.7e-09 5.68e+01 4.09e+02 1.30e+03
406 IgG1
407 IgG1


ANTIBODY PANEL (click on a row in the table)
EPITOPE COMMUNITY (RBD)

blocking

non-blocking

self

3D VIEWER
Epitope Community (RBD)
NEXELIS-PSEUDOVIRUS
No data
RLU value / mAb concentration

No data
RLU value / mAb concentration
No data
RLU value / mAb concentration
ANTIBODY DEPENDENT ENHANCEMENT
No data
No data
DUKE
No data
RAGON
No data
FCGR AFFINITY
IMMUNE EFFECTOR FUNCTION
TEXAS BIOMED
% Survival / Days Post-Infection
% Weight Loss / Days Post-Infection
EM ANALYSIS
NEGATIVE-STAIN EM ANALYSIS