CoVIC ID | Antibody information | Antibody features | Affinity, KD (M) - Duke | Pseudovirus neutralization (PNV-Luciferase; ng/mL) | Pseudovirus neutralization - Beta (PNV-Luciferase; ng/mL) | Pseudovirus neutralization - Delta (PNV-Luciferase; ng/mL) | Authentic virus neutralization (Auth-luciferase ng/mL) - UNC | Authentic virus neutralization (Auth-mNeonGreen ng/mL) - UTMB | In vivo protection survival (%) | Fc Activity - Ragon | Complex formation inhibition (%) | Antibody dependent enhancement | UTMB - ADMP | sequence / structural features | Nexelis - PK | UTMB - ADNKA | Pseudovirus neutralization (PNV-GFP; % infected cells) | Epitope Community (Full-length) | Details | ||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Unblinded ID | Organization | Isotype | Epitope Community (RBD) | D614 | D614G | RBD | NTD | B.1.351 | Omicron | IC50 | IC80 | IC90 | IC50 | IC80 | IC90 | IC50 | IC80 | IC90 | IC50 (WA-1) | IC80 (WA-1) | IC90 (WA-1) | IC50 (B.1.351) | IC80 (B.1.351) | IC50 | IC80 | IC90 | K18 mice | hamsters | ADCP | mADCP | ADNP | mADNP | ADCD (MFI C3) | ADNKA % CD107a+ | ADNKA % MIP-1b+ | FcgR2aR (MFI) | FcgR3aV (MFI) | FcgR2b (MFI) | FcgR3b (MFI) | FcRn (MFI) | mFcR2 (MFI) | mFcR3 (MFI) | mFcR4 (MFI) | Spike: ACE2 | Score (for level of ADE at 10 ug/mL) | IC50 | IC80 | IC90 | Fold increase over virus control | Escape | Structure | GMC for Pre-Spike IgG | GMC for RBD IgG | % CD107a+ | Fold-change CD107a+ | % IFNg+ | Fold-change CD107a+ | % TNFa+ | Fold-change TNFa+ | PNV-G (%infected; 250 ng/ml) | PNV-G BETA (% infected; 250 ng/ml) | PNV-L DELTA (IC50 ng/ml) | PNV-G DELTA (%infected; 250 ng/ml) | PNV-G BA.1 (%infected; 250 ng/ml) | PNV-G BA.1.1 (%infected; 250 ng/ml) | PNV-G BA.2 (%infected; 250 ng/ml) | Community | ||
CC12.3 | None | 5035 | 16232 | 54.642857142857146 | 1.4 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Untreated Infected Control | None | None | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mock Infected Control | None | None | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
mAb-251 | None | 0.0 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
CR3022 | None | moderate | weak | weak | moderate | weak | strong | strong | 5.99 | 6.11 | 4.78 | 5.73 | 3.94 | 5.12 | 5.3 | 6.16 | nt | nt | nt | nt | nt | nt | nt | D | |||||||||||||||||||||||||||||||||||||||||||||
KZ52 | None | weak | moderate | weak | strong | weak | weak | weak | 4.06 | 3.84 | 4.38 | 3.7 | 3.78 | 3.59 | 4.4 | 4.29 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
negative plasma | None | weak | moderate | weak | weak | strong | weak | weak | 4.01 | 3.79 | 4.33 | 3.7 | 3.76 | 3.58 | 4.33 | 4.2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
CC12.14 | None | 1299 | 4989 | 2.1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1 | IgG1 | 1 | 1.63e-09 | 1.75e-10 | 1.46e-06 | 4.19e-08 | 1830.0 | 6370.0 | 14100.0 | 2430.0 | 2510.0 | 2530.0 | 202.0 | >25000 | >25000 | 245 | 662 | 1.24e+03 | 1.65e+03 | 1.95e+03 | weak | moderate | weak | strong | moderate | weak | moderate | 6.09 | 6.05 | 5.48 | 4.83 | 3.5 | 3.93 | 4.87 | 5.66 | 69.6 | 1.2 | 20.50 | 0.90 | 1.32 | 1.02 | 0.05 | 0.06 | 54 | 100 | 202 | 14 | 91 | 100 | 100 | |||||||||||||||||||
2 | IgG1 | 2b | 1.24e-10 | 5.16e-11 | 1.23e-07 | 1.33e-11 | 1470.0 | 4010.0 | 7910.0 | 20.6 | 89.3 | 209.0 | >25000 | >25000 | >25000 | 19 | 60 | 3.03e+02 | 4.69e+02 | 6.05e+02 | 10.0 | strong | strong | strong | strong | moderate | moderate | moderate | 6.34 | 6.28 | 6.01 | 6.42 | 5.65 | 5.96 | 5.89 | 6.63 | 100.0 | 2.0 | Y489H | 0.5mg/kg: 2065.60|1.5mg/kg: 7474.30 | 30.10 | 1.31 | 1.20 | 0.92 | 0.73 | 0.85 | 4 | 2 | 25000 | 92 | 94 | 100 | 93 | H2 | |||||||||||||||
3 | IgG1 | 2c | 1.47e-09 | 8.3e-10 | 8.93e-07 | 2320.0 | 8360.0 | 16000.0 | 705.0 | 2850.0 | 4420.0 | >25000 | >25000 | >25000 | 846 | 2766 | 3.20e+03 | 6.50e+03 | 9.84e+03 | 0.0 | weak | weak | weak | strong | weak | moderate | moderate | 5.87 | 5.99 | 5.0 | 4.39 | 3.63 | 3.94 | 4.68 | 5.03 | 90.3 | 1.12 | 1.5mg/kg: 1527.28 | 13.15 | 0.57 | 0.77 | 0.59 | 0.42 | 0.49 | 43 | 99 | 25000 | 13 | 95 | 100 | 84 | H2 | |||||||||||||||||
4 | IgG1 | 2d | 2.43e-10 | 8.05e-11 | 1.11e-07 | 1.84e-08 | 709.0 | 2480.0 | 5020.0 | 1530.0 | 1560.0 | 1570.0 | 759.0 | 5560.0 | >25000 | 179 | 450 | 1.49e+03 | 2.73e+03 | 3.88e+03 | moderate | weak | weak | strong | weak | moderate | weak | 6.21 | 6.23 | 5.66 | 5.54 | 4.92 | 3.95 | 4.76 | 5.47 | 100.0 | 1.07 | 27.90 | 1.22 | 1.17 | 0.90 | 0.52 | 0.60 | 56 | 100 | 759 | 49 | 88 | 95 | 96 | H2 | ||||||||||||||||||
5 | IgG1 | 2c | 1.08e-09 | 8.64e-10 | 3.98e-07 | 853.0 | 2600.0 | 5260.0 | 29.8 | 186.0 | 406.0 | 158.0 | 415.0 | 679.0 | 433 | 754 | 1.57e+04 | 1.84e+04 | 2.02e+04 | 0.0 | weak | weak | weak | moderate | weak | moderate | moderate | 6.05 | 6.08 | 5.36 | 5.14 | 4.56 | 3.94 | 4.77 | 5.14 | 98.2 | 1.23 | 1.5mg/kg: 1243.76 | 15.65 | 0.68 | 1.36 | 1.05 | 0.04 | 0.05 | 19 | 100 | 158 | 5 | 78 | 91 | 100 | H2 | |||||||||||||||||
6 | IgG1 | 2a | 5.53e-10 | 3.53e-10 | 8.71e-08 | 5.98e-10 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 21.4 | 102.0 | 249.0 | 11861 | 22679 | 2.52e+02 | 4.86e+02 | 7.14e+02 | moderate | moderate | weak | weak | moderate | moderate | weak | 6.05 | 5.94 | 5.65 | 5.87 | 4.09 | 4.59 | 5.11 | 5.91 | 99.0 | 1.28 | 22.65 | 0.99 | 1.34 | 1.03 | 0.89 | 1.03 | 91 | 100 | 21.4 | 59 | 81 | 96 | 98 | A | ||||||||||||||||||
7 | IgG1 | 6b | 1.21e-10 | 3.66e-11 | 1.72e-08 | 4.5e-06 | 4.92e-09 | 53.8 | 146.0 | 261.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 18 | 33 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 10.0 | moderate | moderate | moderate | moderate | weak | moderate | weak | 6.09 | 6.0 | 5.71 | 5.98 | 4.58 | 4.57 | 4.92 | 6.15 | 100.0 | 2.51 | 0.5mg/kg: 1789.63|1.5mg/kg: 7481.71 | 21.40 | 0.93 | 1.57 | 1.21 | 0.07 | 0.08 | 3 | 100 | 25000 | 0 | 90 | 95 | 91 | H1 | |||||||||||||||
8 | IgG1 | 6b | 6.75e-10 | 4.51e-10 | 2.36e-08 | 1.34e-10 | 12800.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2191 | 6355 | 1.02e+04 | 1.13e+04 | 1.21e+04 | moderate | weak | moderate | weak | weak | moderate | weak | 6.34 | 6.28 | 6.01 | 6.38 | 5.35 | 5.49 | 5.22 | 6.41 | 98.0 | 2.85 | 22.90 | 1.00 | 1.62 | 1.25 | 0.03 | 0.03 | 91 | 98 | 25000 | 56 | 86 | 96 | 83 | A | ||||||||||||||||||
9 | IgG1 | 2c | 1.65e-11 | 7.06e-12 | 2.33e-10 | 9.29e-08 | 3.63e-11 | 2.13e-08 | 12.6 | 24.0 | 34.1 | >25000 | >25000 | >25000 | 1140.0 | 1170.0 | 1170.0 | <0.32 | 0.54 | 3035 | 4766 | 4.83e+00 | 8.61e+00 | 1.21e+01 | None | weak | weak | weak | moderate | weak | moderate | weak | 3.75 | 3.75 | 3.67 | 3.72 | 3.45 | 3.87 | 4.18 | 4.64 | 100.0 | 1.96 | 0.5mg/kg: 2099.34 | 23.45 | 1.02 | 1.18 | 0.90 | 0.14 | 0.17 | 0 | 93 | 1140 | 5 | 88 | 97 | 88 | H3 | ||||||||||||
10 | IgG1 | 2c | 1.84e-11 | 8.3e-12 | 2.04e-10 | 8.55e-08 | 3.92e-11 | 3.14e-08 | 10.1 | 21.2 | 32.7 | 464.0 | 2300.0 | 7470.0 | 51.2 | 325.0 | 907.0 | <0.32 | 1 | 5862 | 15389 | 1.18e+01 | 2.19e+01 | 3.15e+01 | None | weak | weak | weak | weak | weak | weak | weak | 3.78 | 3.74 | 3.7 | 3.71 | 3.46 | 3.86 | 4.26 | 4.24 | 100.0 | 1.29 | 0.5mg/kg: 3133.56 | 21.10 | 0.92 | 1.36 | 1.05 | 0.12 | 0.13 | 0 | 100 | 51.2 | 6 | 100 | 94 | 85 | H3 | ||||||||||||
11 | IgG1 | 2c | 2.35e-11 | 9.87e-12 | 2.11e-10 | 4.67e-08 | 2.81e-11 | 4.85e-09 | 6.09 | 16.2 | 28.0 | >25000 | >25000 | >25000 | 159.0 | 656.0 | 1520.0 | <0.32 | 0.93 | 137 | 196 | 1.78e+01 | 2.62e+01 | 3.28e+01 | 90.0 | weak | moderate | weak | moderate | weak | moderate | weak | 3.86 | 3.77 | 3.74 | 3.69 | 3.45 | 3.89 | 4.09 | 4.16 | 99.4 | 0.893 | 0.5mg/kg: 2060.71|1.5mg/kg: 8050.89 | 34.05 | 1.49 | 1.30 | 1.00 | 1.01 | 1.18 | 1 | 6 | 159 | 1 | 97 | 100 | 100 | H3 | ||||||||||||
12 | IgG1 | 2c | 1.11e-11 | 5.07e-12 | 1.64e-10 | 7.55e-08 | 4.24e-11 | 3.66e-08 | 7.48 | 18.6 | 30.6 | 990.0 | 1190.0 | 1250.0 | 352.0 | 1050.0 | 1450.0 | <0.32 | <0.32 | 2526 | 4536 | 8.62e+00 | 1.43e+01 | 1.93e+01 | None | weak | strong | weak | strong | weak | moderate | weak | 3.67 | 3.75 | 3.62 | 3.71 | 3.45 | 3.88 | 4.14 | 4.2 | 100.0 | 2.42 | 0.5mg/kg: 2732.99 | 21.50 | 0.94 | 1.41 | 1.08 | 0.05 | 0.06 | 1 | 70 | 352 | 10 | 100 | 100 | 90 | H3 | ||||||||||||
13 | IgG1 | 2c | 8.95e-12 | 4.71e-12 | 1.16e-10 | 5.11e-08 | 2.42e-11 | 6.07 | 15.4 | 25.3 | 71.7 | 235.0 | 459.0 | 19.4 | 54.8 | 97.5 | <0.32 | 0.85 | 159 | 627 | 4.75e+00 | 7.05e+00 | 8.88e+00 | 70.0 | weak | weak | weak | strong | weak | moderate | moderate | 4.04 | 4.43 | 3.8 | 3.72 | 3.48 | 3.91 | 4.82 | 4.76 | 100.0 | 3.3 | 0.5mg/kg: 4115.36|1.5mg/kg: 10520.90 | 9.65 | 0.42 | 2.07 | 1.59 | 0.47 | 0.55 | 1 | 41 | 19.4 | 1 | 98 | 90 | 92 | H3 | |||||||||||||
14 | IgG1 | 2d | 4.43e-11 | 1.1e-11 | 1.94e-09 | 1.14e-06 | 5.3e-11 | 5.45e-08 | 9.75 | 24.7 | 42.9 | >25000 | >25000 | >25000 | 373.0 | 1490.0 | 7440.0 | <0.32 | <0.32 | >12500 | >12500 | 6.70e-01 | 1.42e+00 | 2.21e+00 | strong | strong | strong | strong | moderate | moderate | strong | 6.37 | 6.32 | 6.02 | 6.46 | 5.71 | 5.99 | 5.74 | 6.6 | 100.0 | 3.49 | 30.05 | 1.31 | 0.97 | 0.75 | 0.76 | 0.88 | 84 | 100 | 373 | 94 | 95 | 83 | 72 | H3 | ||||||||||||||
15 | IgG1 | 2d | 9.47e-11 | 4.56e-11 | 1.19e-08 | 1.19e-07 | 1.22e-09 | 2.88e-09 | 32.0 | 107.0 | 223.0 | >25000 | >25000 | >25000 | 1610.0 | 3140.0 | 3780.0 | 1 | 10 | >12500 | >12500 | 3.12e+01 | 4.93e+01 | 6.44e+01 | strong | strong | strong | strong | strong | moderate | moderate | 6.38 | 6.33 | 6.04 | 6.45 | 5.74 | 6.08 | 5.86 | 6.63 | 100.0 | 3.63 | 22.45 | 0.98 | 1.43 | 1.10 | 0.07 | 0.09 | 1 | 100 | 1610 | 28 | 80 | 85 | 79 | H2 | ||||||||||||||
16 | IgG1 | 2a | 1.57e-10 | 5.04e-11 | 5.31e-09 | 1.03e-06 | 7.34e-10 | 9.66e-09 | 44.5 | 180.0 | 388.0 | 995.0 | >25000 | >25000 | 215.0 | 888.0 | 1380.0 | 10518 | >25000 | 1.61e+04 | 8.58e+04 | 2.28e+05 | moderate | weak | weak | strong | weak | moderate | moderate | 6.15 | 6.15 | 5.36 | 3.9 | 5.09 | 3.94 | 4.91 | 5.04 | 100.0 | 1.54 | 83 | 100 | 215 | 56 | 89 | 84 | 78 | H2 | ||||||||||||||||||||||
17 | IgG1 | 4b | 5.04e-10 | 4.01e-10 | 3.46e-08 | 1.81e-10 | 2.82e-09 | 1030.0 | 3020.0 | 5630.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 8726 | 24853 | 2.50e+04 | 2.50e+04 | 2.50e+04 | strong | moderate | moderate | moderate | moderate | moderate | moderate | 6.33 | 6.28 | 5.99 | 6.4 | 5.49 | 5.67 | 5.66 | 6.51 | 67.0 | 5.79 | 20.55 | 0.90 | 1.44 | 1.10 | 0.09 | 0.10 | 74 | 98 | 25000 | 83 | 79 | 74 | 74 | G | |||||||||||||||||
18 | IgG | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
19 | IgG | 1.08e-09 | 1.18e-09 | 2.64e-08 | 39.7 | 140.0 | 262.0 | 664.0 | >25000 | >25000 | >25000 | >25000 | >25000 | 433 | 1516 | 2.50e+04 | 2.50e+04 | 2.50e+04 | weak | weak | weak | moderate | weak | moderate | weak | 4.07 | 3.8 | 3.83 | 3.73 | 3.45 | 3.93 | 4.75 | 4.54 | 23.7 | 1.42 | ||||||||||||||||||||||||||||||||||
20 | IgG1 | 7.59e-10 | 8.13e-10 | 8.15e-08 | 1.36e-09 | 2.32e-09 | 72.3 | 587.0 | >25000 | 639.0 | 1160.0 | 1350.0 | >25000 | >25000 | >25000 | 236 | 4924 | 2.59e+03 | 9.47e+03 | 2.02e+04 | 10.0 | strong | moderate | moderate | strong | strong | moderate | strong | 6.09 | 6.0 | 5.77 | 6.02 | 4.23 | 4.57 | 5.23 | 6.07 | 9.0 | 3.64 | 0.5mg/kg: 50.30|1.5mg/kg: 58.71 | 24.15 | 1.05 | 1.61 | 1.24 | 0.14 | 0.16 | 12 | 100 | 25000 | 84 | 90 | 83 | 79 | |||||||||||||||||
21 | IgG1 | 7c | 5.02e-10 | 1.4e-09 | 2.08e-10 | 5.25e-10 | 9.26e-09 | 12500.0 | >25000 | >25000 | 162.0 | >25000 | >25000 | >25000 | >25000 | >25000 | 8582 | 20807 | 1.99e+04 | 3.48e+04 | 4.82e+04 | 0.0 | strong | moderate | moderate | moderate | moderate | moderate | weak | 6.29 | 6.22 | 5.95 | 6.3 | 5.2 | 5.14 | 5.34 | 6.28 | 11.6 | 2.69 | 0.5mg/kg: 134.98|1.5mg/kg: 643.01 | 40.20 | 1.76 | 2.06 | 1.58 | 0.51 | 0.59 | 99 | 100 | 25000 | 81 | 91 | 96 | 77 | ||||||||||||||||
22 | IgG1 | 6a | 1.08e-09 | 3e-09 | 1.04e-07 | 3.68e-10 | 1.84e-08 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 0.0 | strong | weak | moderate | weak | weak | moderate | weak | 6.24 | 6.2 | 5.89 | 6.22 | 5.0 | 4.63 | 5.2 | 6.11 | 51.1 | 2.95 | 1.5mg/kg: 1601.37 | 12.20 | 0.53 | 6.80 | 5.23 | 0.73 | 0.85 | 90 | 100 | 25000 | 71 | 97 | 100 | 79 | ||||||||||||||
23 | IgG1 | 5b | 3.72e-10 | 5.86e-10 | 7.13e-08 | 2e-10 | 4.25e-09 | 14200.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 0.0 | strong | moderate | moderate | weak | moderate | moderate | weak | 6.27 | 6.22 | 5.93 | 6.27 | 4.82 | 5.04 | 5.09 | 6.27 | 36.3 | 5.49 | 1.5mg/kg: 158.53 | 18.15 | 0.79 | 1.63 | 1.25 | 0.12 | 0.13 | 87 | 100 | 25000 | 87 | 90 | 90 | 82 | E4 | |||||||||||||
24 | IgG1 | 7b | 1.21e-09 | 2.3e-09 | 1.46e-08 | 7.49e-10 | 2.55e-08 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 14175 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 0.0 | moderate | strong | weak | weak | weak | strong | moderate | 6.22 | 6.18 | 5.86 | 6.23 | 5.08 | 4.78 | 5.17 | 6.21 | 48.7 | 3.48 | 1.5mg/kg: 3119.58 | 33.00 | 1.44 | 0.84 | 0.65 | 1.14 | 1.33 | 100 | 100 | 25000 | 86 | 98 | 100 | 91 | ||||||||||||||||
25 | IgG1 | 7b | 1.07e-09 | 1.9e-09 | 8.49e-08 | 6.96e-09 | 8.2e-08 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | moderate | strong | moderate | weak | moderate | moderate | 5.77 | 5.93 | 5.07 | 5.59 | 3.78 | 4.02 | 4.91 | 5.71 | 31.2 | 2.47 | 21.40 | 1.15 | 1.68 | 5.00 | 0.63 | 1.05 | 89 | 100 | 25000 | 98 | 100 | 95 | 95 | ||||||||||||||||||
26 | IgG1 | 7b | 6.57e-10 | 1.18e-09 | 3.88e-08 | 5.36e-09 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 0.0 | strong | weak | moderate | strong | weak | moderate | moderate | 6.22 | 6.14 | 5.81 | 6.16 | 4.75 | 4.54 | 5.25 | 6.14 | 31.8 | 5.8 | 1.5mg/kg: 630.67 | 19.20 | 1.04 | 0.84 | 2.52 | 0.46 | 0.76 | 82 | 99 | 25000 | 85 | 89 | 95 | 100 | ||||||||||||||||||||
27 | IgG1 | 3a | 3.59e-09 | 1.42e-09 | 1.48e-07 | 2.62e-10 | 8.91e-08 | 8250.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 260 | 2457 | 1173 | 4632 | 2.07e+04 | 3.24e+04 | 4.22e+04 | strong | moderate | moderate | strong | weak | moderate | moderate | 6.19 | 6.13 | 5.87 | 6.24 | 5.23 | 5.04 | 5.3 | 6.34 | 88.6 | 6.13 | 24.55 | 1.32 | 1.69 | 5.04 | 0.61 | 1.02 | 72 | 92 | 25000 | 68 | 80 | 90 | 89 | A | |||||||||||||||
28 | IgG1 | 6b | 3.3e-10 | 5.22e-10 | 1.23e-08 | 1.26e-10 | 2.32e-08 | 512.0 | 1960.0 | 3960.0 | 755.0 | 1400.0 | 1760.0 | 308.0 | >25000 | >25000 | 190 | 815 | 398 | 897 | 3.19e+03 | 4.68e+03 | 5.85e+03 | 0.0 | strong | moderate | moderate | strong | weak | moderate | moderate | 6.36 | 6.3 | 6.02 | 6.42 | 5.63 | 5.9 | 5.61 | 6.55 | 100.0 | 6.13 | 0.5mg/kg: 1908.96|1.5mg/kg: 3954.73 | 27.10 | 1.46 | 1.84 | 5.49 | 0.67 | 1.12 | 57 | 65 | 308 | 37 | 75 | 86 | 84 | A | |||||||||||||
29 | IgG1 | 4.33e-10 | 3.5e-10 | 3.99e-07 | 1020.0 | 1520.0 | 1750.0 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | weak | weak | strong | weak | moderate | weak | 6.24 | 6.18 | 5.89 | 6.2 | 4.64 | 4.74 | 5.15 | 6.16 | 5.0 | 19.25 | 1.04 | 0.77 | 2.28 | 0.68 | 1.13 | 84 | 100 | 25000 | 77 | 81 | 84 | 77 | E2 | ||||||||||||||||||||||||
30 | IgG1 | 2d | 3.21e-11 | 5.94e-12 | 4.1e-09 | 2.73e-06 | 8.87 | 26.8 | 50.7 | 518.0 | 1650.0 | >25000 | 47.1 | 113.0 | 200.0 | 2 | 6 | >25000 | >25000 | 2.75e+01 | 5.23e+01 | 7.61e+01 | 100.0 | strong | strong | strong | moderate | moderate | moderate | moderate | 6.36 | 6.3 | 6.02 | 6.45 | 5.72 | 6.06 | 5.53 | 6.59 | 100.0 | 7.37 | E484A | 0.5mg/kg: 2456.41|1.5mg/kg: 8195.59 | 25.45 | 1.37 | 1.31 | 3.91 | 0.59 | 0.99 | 0 | 100 | 47.1 | 3 | 74 | 80 | 81 | H3 | |||||||||||||
31 | IgG1 | 4b | 1.42e-10 | 8.08e-11 | 7.02e-08 | 3.96e-10 | 11400.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 949 | 2233 | 1.21e+04 | 4.33e+04 | 9.12e+04 | 10.0 | strong | weak | moderate | moderate | moderate | moderate | moderate | 6.3 | 6.26 | 5.97 | 6.4 | 5.68 | 6.03 | 5.67 | 6.6 | 99.0 | 2.57 | 1.5mg/kg: 2850.55 | 24.85 | 1.34 | 0.96 | 2.87 | 0.80 | 1.33 | 74 | 100 | 25000 | 52 | 83 | 79 | 78 | G | ||||||||||||||||
32 | IgG1 | 2d | 5.76e-11 | 1.85e-11 | 1.76e-09 | 1.96e-06 | 2.04e-10 | 8.66 | 32.3 | 66.4 | >25000 | >25000 | >25000 | 1.08 | 1.06 | 1.06 | 2 | 8 | 735 | 2676 | 6.11e+01 | 1.44e+02 | 2.37e+02 | 60.0 | strong | strong | strong | moderate | moderate | moderate | weak | 6.39 | 6.32 | 6.05 | 6.46 | 5.72 | 6.08 | 5.68 | 6.61 | 100.0 | 2.65 | G496V|S494L | 0.5mg/kg: 3150.21|1.5mg/kg: 6774.03 | 26.20 | 1.41 | 0.74 | 2.22 | 0.78 | 1.29 | 0 | 89 | 1.08 | 73 | 83 | 80 | 72 | H3 | ||||||||||||
33 | IgG1 | 3.32e-08 | 1.63e-08 | 4.8e-06 | 8.18e-08 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 5650.0 | 7400.0 | 7930.0 | 18 | 44 | 259 | 637 | 4.57e+03 | 6.06e+03 | 7.14e+03 | 10.0 | strong | weak | weak | weak | weak | moderate | moderate | 4.35 | 4.01 | 3.81 | 3.77 | 3.48 | 3.94 | 4.91 | 5.23 | 7.6 | 3.29 | 24.30 | 1.31 | 0.56 | 1.67 | 0.91 | 1.52 | 46 | 100 | 5650 | 81 | 86 | 81 | 70 | |||||||||||||||||
34 | IgG1 | 2.37e-09 | 1.74e-09 | 3.92e-09 | 5.29e-08 | 162.0 | 453.0 | 1050.0 | 1.13 | 1.12 | 1.12 | >25000 | >25000 | >25000 | 201 | 19356 | 1.02e+04 | 2.14e+04 | 3.30e+04 | 0.0 | moderate | moderate | weak | weak | weak | moderate | strong | 6.0 | 5.97 | 5.52 | 5.7 | 4.31 | 4.12 | 5.01 | 5.71 | 6.4 | 2.3 | 1.5mg/kg: 50.30 | 19.80 | 1.07 | 0.84 | 2.51 | 0.94 | 1.57 | 14 | 99 | 25000 | 75 | 86 | 72 | 74 | ||||||||||||||||||
35 | IgG1 | 7c | 1.68e-09 | 1.05e-09 | 2.81e-09 | 4.34e-10 | 2.3e-08 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 0.0 | strong | strong | moderate | weak | weak | moderate | weak | 6.21 | 6.2 | 5.9 | 6.25 | 5.33 | 5.21 | 5.31 | 6.22 | 7.1 | 3.24 | 1.5mg/kg: 1842.61 | 24.50 | 1.32 | 0.76 | 2.25 | 0.59 | 0.99 | 90 | 100 | 25000 | 80 | 94 | 82 | 74 | ||||||||||||||||
36 | IgG1 | 4.36e-09 | 4.96e-09 | 9.51e-07 | 86.2 | 6600.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 4 | 14 | >25000 | >25000 | 3.07e+01 | 1.18e+02 | 2.59e+02 | 60.0 | moderate | moderate | weak | weak | weak | moderate | weak | 6.18 | 6.11 | 5.87 | 6.18 | 5.04 | 5.07 | 5.06 | 6.21 | 3.1 | del68-70 | 0.5mg/kg: 63.45 | 23.85 | 1.29 | 0.61 | 1.82 | 0.15 | 0.25 | 30 | 100 | 25000 | 85 | 100 | 84 | 87 | |||||||||||||||||
37 | IgG1 | 1.9e-08 | 3.96e-08 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | moderate | weak | weak | weak | moderate | weak | 5.19 | 5.28 | 4.44 | 4.15 | 3.53 | 3.92 | 4.86 | 5.2 | 3.9 | 0.459 | 22.15 | 1.19 | 0.64 | 1.91 | 1.16 | 1.93 | 87 | 100 | 25000 | 90 | 98 | 92 | 100 | ||||||||||||||||||||||
38 | IgG | 6b | 1.09e-09 | 4.54e-10 | 7.05e-09 | 1.4e-10 | 297.0 | 1310.0 | 2900.0 | 863.0 | 2170.0 | 2740.0 | 376.0 | 1820.0 | 2920.0 | 16 | 78 | 41 | 123 | 3.45e+02 | 7.16e+02 | 1.10e+03 | None | moderate | moderate | moderate | strong | moderate | moderate | strong | 6.35 | 6.3 | 6.01 | 6.42 | 5.52 | 5.76 | 5.48 | 6.45 | 99.3 | 1.05 | 0.5mg/kg: 176.64 | 21.40 | 1.15 | 0.59 | 1.76 | 0.54 | 0.90 | 31 | 24 | 376 | 7 | 92 | 90 | 87 | A | ||||||||||||||
39 | IgG | 2d | 3.12e-11 | 1.06e-11 | 1.78e-09 | 1.66e-06 | 3.33e-08 | 4.13e-08 | 7.11 | 20.1 | 35.8 | >25000 | >25000 | >25000 | 124.0 | 333.0 | 750.0 | <0.32 | <0.32 | 12500 | 12500 | 1.66e+01 | 2.68e+01 | 3.56e+01 | None | strong | strong | strong | strong | moderate | moderate | moderate | 6.36 | 6.32 | 6.03 | 6.47 | 5.71 | 6.01 | 5.7 | 6.61 | 100.0 | 1.47 | L452P | 0.5mg/kg: 3296.86 | 24.60 | 1.33 | 0.98 | 2.94 | 0.86 | 1.43 | 0 | 100 | 124 | 6 | 82 | 91 | 82 | H3 | |||||||||||
40 | IgG | 2d | 7.15e-11 | 3.82e-11 | 1.68e-08 | 6.92e-09 | 4.03e-08 | 248.0 | 825.0 | 1590.0 | >25000 | >25000 | >25000 | 289.0 | 1540.0 | 3400.0 | 76 | 216 | >25000 | >25000 | 4.76e+02 | 1.46e+03 | 2.80e+03 | None | strong | moderate | strong | strong | weak | moderate | moderate | 6.37 | 6.31 | 6.03 | 6.45 | 5.71 | 6.06 | 5.82 | 6.63 | 100.0 | 0.868 | F490C|F490L|F490V | 0.5mg/kg: 1926.61 | 18.80 | 1.01 | 0.47 | 1.42 | 0.91 | 1.52 | 24 | 85 | 289 | 9 | 87 | 90 | 87 | H3 | ||||||||||||
41 | IgG1 | 2.33e-10 | 2.49e-10 | 2.75e-08 | 1.06e-10 | 7.77e-10 | 6450.0 | 23200.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 5997 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 100.0 | strong | weak | moderate | moderate | weak | moderate | weak | 6.3 | 6.25 | 5.95 | 6.35 | 5.51 | 5.6 | 4.6 | 6.36 | 1.02 | 1.5mg/kg: 15897.03 | 23.00 | 1.24 | 0.66 | 1.97 | 1.05 | 1.76 | 82 | 100 | 25000 | 70 | 89 | 82 | 88 | ||||||||||||||||||
42 | IgG1 | 2a | 4.84e-10 | 1.59e-10 | 1.1e-08 | 4.47e-10 | 57.6 | 185.0 | 348.0 | 1000.0 | 21700.0 | >25000 | 13.8 | 53.8 | 124.0 | 14 | 44 | 2246 | 6637 | 7.81e+02 | 1.81e+03 | 2.95e+03 | 0.0 | strong | moderate | strong | moderate | moderate | moderate | moderate | 6.37 | 6.3 | 6.02 | 6.45 | 5.61 | 5.87 | 5.44 | 6.56 | 98.8 | 0.626 | 0.5mg/kg: 3894.89 | 21.45 | 1.16 | 0.41 | 1.22 | 0.40 | 0.67 | 6 | 74 | 13.8 | 1 | 83 | 95 | 81 | H1 | ||||||||||||||
43 | IgG4 | 2c | 1.94e-10 | 9.59e-11 | 2.27e-08 | 1.48e-08 | 34.1 | 109.0 | 210.0 | >25000 | >25000 | >25000 | 3.2 | 17.5 | 47.5 | 13 | 31 | 1672 | 3234 | 1.22e+03 | 2.06e+03 | 2.81e+03 | 10.0 | strong | weak | moderate | weak | weak | moderate | moderate | 6.38 | 6.11 | 6.01 | 3.8 | 5.72 | 4.02 | 4.25 | 4.98 | 100.0 | 0.718 | 0.5mg/kg: 206.34|1.5mg/kg: 778.93 | 22.20 | 1.20 | 0.82 | 2.46 | 0.83 | 1.39 | 0 | 100 | 3.2 | 1 | 90 | 85 | 75 | |||||||||||||||
44 | IgG1 | 2c | 1.42e-10 | 1.98e-10 | 4.74e-08 | 53.4 | 163.0 | 302.0 | >25000 | >25000 | >25000 | 102.0 | 265.0 | 432.0 | 5 | 19 | >25000 | >25000 | 4.26e+02 | 1.01e+03 | 1.66e+03 | 30.0 | strong | moderate | moderate | moderate | weak | moderate | weak | 6.3 | 6.24 | 5.98 | 6.4 | 5.61 | 5.94 | 5.57 | 6.53 | 100.0 | 1.41 | 1.5mg/kg: 1312.88 | 24.15 | 1.30 | 0.78 | 2.31 | 0.80 | 1.33 | 2 | 100 | 102 | 1 | 77 | 88 | 65 | ||||||||||||||||
45 | IgG4 | 2c | 1.7e-10 | 3.6e-11 | 3.67e-08 | 8.06 | 27.7 | 55.2 | >25000 | >25000 | >25000 | 5.47 | 28.6 | 68.7 | 2 | 8 | >25000 | >25000 | 1.04e+02 | 1.56e+02 | 1.98e+02 | 30.0 | moderate | weak | moderate | weak | weak | moderate | weak | 6.37 | 6.2 | 6.02 | 3.82 | 5.69 | 4.03 | 4.29 | 5.44 | 100.0 | 1.85 | 0.5mg/kg: 372.94|1.5mg/kg: 1152.88 | 18.90 | 1.02 | 0.66 | 1.96 | 0.72 | 1.20 | 2 | 100 | 5.47 | 1 | 74 | 75 | 63 | ||||||||||||||||
46 | IgG1 | 2.98e-09 | 3.14e-08 | >25000 | >25000 | >25000 | 2230.0 | 3430.0 | 3800.0 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | weak | moderate | weak | weak | weak | moderate | weak | 4.14 | 3.92 | 3.84 | 3.72 | 3.5 | 3.9 | 4.85 | 5.39 | 6.5 | 1.23 | 35.20 | 1.90 | 0.76 | 2.27 | 0.63 | 1.05 | 94 | 100 | 2230 | 74 | 88 | 82 | 70 | |||||||||||||||||||||||||
47 | IgG4 | 2.73e-09 | 3.18e-09 | 3.55e-08 | 4610.0 | 11000.0 | 18900.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | weak | moderate | weak | weak | weak | moderate | weak | 4.54 | 4.86 | 3.98 | 4.25 | 3.69 | 3.92 | 4.85 | 4.63 | 24.4 | 2.53 | T588A | 23.10 | 1.25 | 0.59 | 1.76 | 0.94 | 1.57 | 90 | 100 | 25000 | 77 | 91 | 74 | 81 | ||||||||||||||||||||
48 | IgG1 | 2a | 4.28e-10 | 1.51e-10 | 1.22e-07 | 2.19e-08 | 1150.0 | 3620.0 | 13300.0 | >25000 | >25000 | >25000 | 115.0 | 696.0 | >25000 | 426 | 1028 | 2.82e+03 | 4.63e+03 | 6.18e+03 | moderate | moderate | weak | weak | weak | moderate | weak | 6.22 | 6.17 | 5.86 | 6.22 | 4.61 | 4.46 | 5.02 | 6.13 | 100.0 | 3.14 | 23.35 | 1.26 | 1.07 | 3.19 | 0.52 | 0.86 | 57 | 100 | 115 | 9 | 98 | 77 | 81 | |||||||||||||||||||
49 | IgG4 | 2a | 3.41e-10 | 1.36e-10 | 1.48e-07 | 1.39e-08 | 57.4 | 219.0 | 506.0 | 2540.0 | 3720.0 | 4100.0 | 35.7 | 133.0 | 259.0 | 110 | 256 | 2.24e+03 | 9.30e+03 | 2.14e+04 | 0.0 | moderate | moderate | moderate | weak | weak | weak | weak | 6.13 | 5.75 | 5.88 | 3.74 | 5.57 | 3.98 | 4.58 | 4.61 | 100.0 | 2.67 | 1.5mg/kg: 1233.73 | 23.80 | 1.28 | 0.92 | 2.75 | 0.58 | 0.97 | 26 | 100 | 35.7 | 2 | 99 | 91 | 91 | |||||||||||||||||
50 | IgG1 | 2a | 4.68e-10 | 1.75e-10 | 7.87e-08 | 1.89e-08 | 869.0 | 3110.0 | 6470.0 | >25000 | >25000 | >25000 | 116.0 | 398.0 | 1480.0 | 70 | 322 | >25000 | >25000 | 4.58e+03 | 1.11e+04 | 1.87e+04 | strong | weak | moderate | strong | weak | moderate | moderate | 6.23 | 6.19 | 5.86 | 6.21 | 4.63 | 4.58 | 5.14 | 6.12 | 100.0 | 1.27 | K417E | 25.95 | 1.40 | 0.92 | 2.73 | 0.67 | 1.11 | 28 | 100 | 116 | 3 | 79 | 93 | 90 | ||||||||||||||||
51 | IgG1 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | weak | weak | weak | strong | weak | moderate | strong | 4.48 | 3.87 | 3.79 | 3.72 | 3.46 | 3.94 | 4.92 | 4.72 | 13.5 | 0.716 | 25.80 | 1.39 | 1.22 | 3.64 | 0.61 | 1.02 | 89 | 99 | 25000 | 54 | 82 | 79 | 74 | |||||||||||||||||||||||||||
52 | IgG1 | 2a | 2.47e-10 | 1.57e-10 | 1.71e-09 | 6.94e-09 | 221.0 | 606.0 | 1080.0 | >25000 | >25000 | >25000 | 134.0 | 471.0 | 739.0 | 64 | 187 | >25000 | >25000 | 6.07e+02 | 1.49e+03 | 2.52e+03 | 0.0 | strong | moderate | strong | strong | moderate | moderate | moderate | 6.36 | 6.29 | 6.02 | 6.44 | 5.65 | 5.87 | 5.41 | 6.56 | 95.0 | 1.38 | Y489H | 1.5mg/kg: 4210.07 | 24.65 | 1.33 | 1.07 | 3.19 | 0.55 | 0.92 | 18 | 99 | 134 | 6 | 82 | 84 | 75 | H2 | |||||||||||||
53 | IgG1 | 6e-10 | 2.37e-08 | 189.0 | 801.0 | 1730.0 | 34.7 | 185.0 | 524.0 | 86.5 | 559.0 | 1130.0 | 95 | 242 | 249 | 800 | 5.91e+03 | 9.09e+03 | 1.17e+04 | 0.0 | moderate | weak | weak | strong | weak | moderate | moderate | 5.45 | 5.44 | 4.8 | 4.96 | 3.5 | 3.92 | 4.86 | 5.19 | 70.0 | 1.04 | 1.5mg/kg: 50.30 | 22.45 | 1.21 | 1.10 | 3.28 | 0.68 | 1.13 | 100 | 100 | 86.5 | 59 | 54 | 55 | 56 | ||||||||||||||||||
54 | 7a | 8.65e-10 | 2.44e-09 | 2.44e-07 | 8.76e-11 | 1.58e-08 | 37.0 | 87.4 | 139.0 | 26.4 | 68.2 | 111.0 | 12.9 | 37.8 | 64.4 | 6 | 22 | 2 | 6 | 2.44e+02 | 3.44e+02 | 4.21e+02 | weak | weak | weak | moderate | weak | moderate | weak | 4.19 | 3.75 | 3.86 | 3.74 | 3.47 | 3.9 | 4.94 | 4.6 | 99.5 | 0.864 | S375F|S375F,D1118H | 6.90 | 0.37 | 0.47 | 1.40 | 0.58 | 0.97 | 1 | 3 | 12.9 | 0 | 39 | 34 | 96 | C2 | |||||||||||||||
55 | IgG1 | 1.56e-10 | 5.8e-11 | 1.15e-07 | 3.12e-11 | 1.81e-08 | 13.1 | 38.3 | 70.7 | 5.98 | 23.0 | 48.2 | 5.47 | 17.0 | 30.6 | 13 | 27 | 60 | 125 | 2.49e+02 | 3.85e+02 | 4.97e+02 | 0.0 | strong | moderate | moderate | strong | moderate | moderate | strong | 6.37 | 6.28 | 6.01 | 6.42 | 5.59 | 5.74 | 5.53 | 6.45 | 100.0 | 1.12 | 1.5mg/kg: 142.39 | 24.20 | 1.30 | 0.94 | 2.79 | 1.04 | 1.73 | 0 | 0 | 5.47 | 0 | 2 | 2 | 77 | C2 | ||||||||||||||
56 | IgG1 | 1.13e-10 | 3.82e-11 | 9.42e-08 | 1.64e-05 | 3e-11 | 1.83e-08 | 6.36 | 24.3 | 51.7 | 1.52 | 6.68 | 16.5 | 1.74 | 5.53 | 10.5 | 2 | 7 | 6 | 20 | 1.02e+02 | 1.77e+02 | 2.44e+02 | 0.0 | strong | weak | moderate | strong | weak | moderate | moderate | 6.33 | 6.23 | 5.96 | 6.34 | 5.41 | 5.27 | 5.34 | 6.32 | 100.0 | 1.86 | 1.5mg/kg: 50.30 | 26.50 | 1.43 | 1.19 | 3.54 | 0.51 | 0.85 | 0 | 0 | 1.74 | 0 | 1 | 1 | 72 | C2 | |||||||||||||
57 | 1.36e-09 | 2.28e-09 | 2.04e-07 | 1.53e-10 | 4.16e-09 | 10.2 | 26.1 | 45.3 | 1.06 | 3.54 | 7.11 | 3.08 | 9.16 | 17.7 | 1 | 5 | 3 | 13 | 5.15e+01 | 1.21e+02 | 1.99e+02 | 92.7 | 0.66 | 19.60 | 1.06 | 1.23 | 3.66 | 0.60 | 1.00 | 0 | 0 | 3.08 | 0 | 3 | 1 | 71 | C2 | ||||||||||||||||||||||||||||||||
58 | IgG1 | 7a | 2.98e-09 | 9.59e-10 | 1.39e-07 | 5.68e-11 | 4.6 | 13.6 | 24.7 | 0.805 | 3.1 | 6.51 | 0.45 | 1.74 | 3.19 | 5 | 16 | 14 | 27 | 8.74e+01 | 1.11e+02 | 1.27e+02 | strong | moderate | weak | strong | weak | weak | weak | 5.29 | 5.52 | 3.75 | 3.65 | 4.13 | 4.15 | 5.41 | 5.29 | 100.0 | 2.12 | 20.80 | 1.12 | 0.85 | 2.54 | 0.90 | 1.49 | 0 | 1 | 0.45 | 0 | 3 | 2 | 69 | C2 | ||||||||||||||||
59 | 7a | 4.76e-10 | 1.2e-09 | 2.01e-07 | 7.63e-11 | 1.16e-08 | 3.7 | 11.8 | 22.5 | 1.24 | 4.07 | 9.24 | 2.75 | 10.4 | 17.7 | 1 | 1 | <0.32 | 4 | 8.90e+01 | 1.16e+02 | 1.35e+02 | weak | weak | weak | weak | weak | moderate | weak | 3.98 | 3.75 | 3.8 | 3.73 | 3.46 | 3.9 | 4.83 | 4.7 | 99.4 | 0.957 | S371F | 21.00 | 1.11 | 1.64 | 3.28 | 0.99 | 2.91 | 0 | 2 | 2.75 | 0 | 1 | 1 | 72 | C2 | |||||||||||||||
60 | 0.45 | 2 | 0.37 | 2 | 1.34e+01 | 2.07e+01 | 2.66e+01 | 0.486 | 20.20 | 1.07 | 1.34 | 2.69 | 0.55 | 1.62 | 0 | 0 | 0 | 1 | 2 | 88 | |||||||||||||||||||||||||||||||||||||||||||||||||
61 | 7a | 6.2e-10 | 1.3e-09 | 1.95e-07 | 5.25e-11 | 2.04e-09 | 4.96 | 15.8 | 30.8 | 0.886 | 4.0 | 10.2 | 2.28 | 8.63 | 18.5 | 2 | 5 | <0.32 | 3 | 9.05e+01 | 1.32e+02 | 1.65e+02 | weak | moderate | weak | weak | weak | moderate | weak | 4.04 | 3.78 | 3.78 | 3.7 | 3.46 | 3.91 | 4.9 | 4.86 | 99.5 | 0.996 | D442A | 19.50 | 1.03 | 1.29 | 2.59 | 1.77 | 5.21 | 1 | 0 | 2.28 | 0 | 2 | 1 | 96 | C2 | |||||||||||||||
62 | IgG1 | 7a | 2.04e-10 | 4.77e-11 | 6.38e-08 | 1.61e-05 | 3.55e-11 | 1.47e-08 | 8.46 | 34.5 | 74.3 | 4.14 | 14.1 | 27.5 | 7.96 | 26.0 | 49.2 | 4 | 8 | 4 | 15 | 1.84e+02 | 3.76e+02 | 5.71e+02 | 0.0 | moderate | strong | moderate | strong | weak | moderate | moderate | 6.32 | 6.24 | 5.97 | 6.36 | 5.41 | 5.04 | 5.32 | 6.29 | 100.0 | 1.32 | 1.5mg/kg: 50.63 | 23.45 | 1.24 | 1.54 | 3.09 | 0.67 | 1.96 | 0 | 0 | 7.96 | 1 | 0 | 0 | 87 | C2 | ||||||||||||
63 | 7a | 4.52e-10 | 1.07e-09 | 1.85e-07 | 6.04e-11 | 4.26e-09 | 2.75 | 10.8 | 23.4 | >25000 | >25000 | >25000 | 4.05 | 11.0 | 19.1 | <0.32 | 1 | <0.32 | 0.48 | 1.64e+01 | 3.65e+01 | 5.84e+01 | weak | moderate | weak | weak | weak | moderate | weak | 4.36 | 3.83 | 3.78 | 3.73 | 3.47 | 3.93 | 4.93 | 4.43 | 99.8 | 1.35 | Y508H | 20.85 | 1.10 | 1.25 | 2.50 | 0.51 | 1.50 | 0 | 0 | 4.05 | 1 | 2 | 1 | 90 | C2 | |||||||||||||||
64 | 7a | 7.08e-10 | 1.3e-09 | 1.69e-07 | 1.34e-10 | 1.85e-08 | 11.6 | 24.6 | 39.2 | 25.5 | 68.3 | 93.9 | 2.53 | 10.3 | 20.1 | 3 | 13 | <0.32 | 4 | 6.20e+01 | 8.84e+01 | 1.09e+02 | weak | moderate | weak | weak | weak | moderate | weak | 3.94 | 3.8 | 3.82 | 3.73 | 3.46 | 3.92 | 4.86 | 4.41 | 96.6 | 1.16 | del374,Y508H|del374,D571G | 22.40 | 1.18 | 1.49 | 2.98 | 0.62 | 1.84 | 0 | 0 | 2.53 | 1 | 9 | 6 | 95 | C3 | |||||||||||||||
65 | IgG1 | 7a | 1.01e-10 | 4.01e-11 | 5.1e-08 | 2.84e-11 | 1.92e-08 | 10.8 | 29.2 | 51.1 | 1.01 | 5.96 | 11.1 | 3.02 | 10.4 | 21.1 | 16 | 26 | 18 | 36 | 2.50e+02 | 4.05e+02 | 5.37e+02 | moderate | weak | moderate | strong | weak | moderate | moderate | 6.32 | 6.27 | 5.97 | 6.42 | 5.65 | 5.77 | 5.61 | 6.48 | 100.0 | 1.72 | K417E | 21.40 | 1.13 | 1.45 | 2.90 | 0.68 | 1.99 | 0 | 0 | 3.02 | 0 | 6 | 6 | 96 | C3 | ||||||||||||||
66 | 5.89e-10 | 1.14e-09 | 1.4e-07 | 1.29e-10 | 1.88e-08 | 4.17 | 11.0 | 19.5 | 4.47 | 15.2 | 31.9 | 8.61 | 26.7 | 49.6 | 1 | 3 | <0.32 | 4 | 1.12e+02 | 3.10e+02 | 5.62e+02 | weak | weak | weak | strong | weak | moderate | strong | 4.28 | 4.07 | 3.88 | 3.85 | 3.47 | 3.9 | 4.94 | 4.75 | 100.0 | 1.18 | 21.75 | 1.15 | 1.65 | 3.30 | 0.71 | 2.10 | 0 | 0 | 8.61 | 0 | 4 | 8 | 73 | C3 | |||||||||||||||||
67 | IgG1 | 2a | 1.39e-09 | 6.13e-10 | 2.85e-07 | 1.81e-10 | 7.33e-08 | 17500.0 | >25000 | >25000 | >25000 | >25000 | >25000 | 21.7 | 419.0 | 1160.0 | 3404 | 12080 | 1.99e+03 | 3.49e+03 | 4.85e+03 | 0.0 | strong | weak | moderate | strong | weak | moderate | moderate | 6.19 | 6.13 | 5.77 | 6.15 | 4.77 | 4.67 | 5.22 | 6.22 | 100.0 | 1.33 | 0.5mg/kg: 152.54|1.5mg/kg: 665.62 | 23.10 | 1.22 | 1.30 | 2.60 | 0.56 | 1.65 | 62 | 70 | 21.7 | 29 | 78 | 92 | 83 | ||||||||||||||||
68 | IgG1 | 2d | 4.3e-11 | 3.61e-11 | 2.89e-09 | 2.82e-07 | 2.05e-09 | 2.36e-09 | 9.83 | 25.8 | 43.8 | >25000 | >25000 | >25000 | 10.3 | 30.1 | 54.8 | 1 | 1 | >25000 | >25000 | 5.93e+01 | 8.74e+01 | 1.10e+02 | None | strong | strong | strong | strong | moderate | moderate | strong | 6.39 | 6.33 | 6.03 | 6.46 | 5.73 | 6.14 | 5.91 | 6.59 | 100.0 | 1.47 | 0.5mg/kg: 736.35 | 40.55 | 2.14 | 2.33 | 4.65 | 1.39 | 4.07 | 0 | 98 | 10.3 | 0 | 88 | 90 | 91 | H2 | ||||||||||||
69 | IgG1 | 1 | 1.36e-09 | 2.2e-10 | 2.67e-08 | 7.05e-11 | 8.92e-10 | 6840.0 | 20200.0 | >25000 | 262.0 | >25000 | >25000 | 558.0 | 1730.0 | 2320.0 | 482 | 2470 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 0.0 | strong | moderate | moderate | moderate | weak | moderate | strong | 6.32 | 6.26 | 5.99 | 6.41 | 5.61 | 5.88 | 5.28 | 6.56 | 74.1 | 2.52 | 1.5mg/kg: 501.00 | 33.90 | 1.79 | 1.05 | 2.11 | 1.07 | 3.16 | |||||||||||||||||||||||
70 | 2.62e-09 | 3.79e-09 | 1.3e-07 | 6.34e-09 | 606.0 | 3820.0 | 9900.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 4929 | 19977 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | weak | weak | weak | moderate | weak | weak | weak | 4.21 | 3.9 | 3.89 | 3.75 | 3.48 | 3.93 | 5.0 | 4.72 | 86.9 | 1.11 | 24.75 | 1.31 | 1.30 | 2.61 | 0.55 | 1.62 | ||||||||||||||||||||||||||
71 | 2.51e-09 | 1.27e-09 | 1.29e-07 | 5.91e-10 | 876.0 | 5810.0 | 18200.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 18221 | >25000 | >12500 | >12500 | 2.50e+04 | 2.50e+04 | 2.50e+04 | weak | weak | moderate | moderate | weak | moderate | moderate | 4.2 | 3.87 | 3.85 | 5.34 | 3.47 | 3.92 | 5.02 | 4.72 | 90.1 | 1.26 | 23.55 | 1.24 | 1.45 | 2.90 | 0.66 | 1.94 | ||||||||||||||||||||||||||
72 | 2.8e-09 | 3.72e-09 | 3.14e-08 | 5.65e-09 | 137.0 | 536.0 | 1110.0 | >25000 | >25000 | >25000 | 189.0 | 913.0 | 2190.0 | 362 | 898 | >12500 | >12500 | 5.20e+02 | 1.01e+03 | 1.48e+03 | weak | moderate | moderate | weak | weak | moderate | moderate | 4.16 | 3.81 | 3.82 | 3.72 | 3.48 | 3.91 | 4.81 | 4.43 | 98.8 | 0.639 | ||||||||||||||||||||||||||||||||
73 | 2a | 2.85e-09 | 4.54e-09 | 2.49e-08 | 6.99e-09 | 302.0 | 1460.0 | 3270.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 364 | 1119 | >12500 | >12500 | 3.13e+03 | 5.68e+03 | 8.04e+03 | weak | weak | weak | weak | weak | moderate | moderate | 4.21 | 4.07 | 3.87 | 3.72 | 3.47 | 3.95 | 4.95 | 4.63 | 100.0 | 1.45 | 37.85 | 2.00 | 2.06 | 4.11 | 1.43 | 4.21 | 66 | 100 | 25000 | 36 | 95 | 95 | 100 | ||||||||||||||||||
74 | IgG1 | 3a | 5.52e-10 | 2.73e-10 | 3.42e-08 | 1.44e-10 | 5.56e-08 | 78.2 | 2600.0 | 9560.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 78 | 543 | 44 | 220 | 1.55e+03 | 3.63e+03 | 5.96e+03 | 0.0 | strong | strong | moderate | weak | weak | moderate | strong | 6.22 | 6.18 | 5.9 | 6.27 | 5.25 | 4.99 | 5.28 | 6.37 | 96.2 | 1.7 | 0.5mg/kg: 511.23|1.5mg/kg: 1286.76 | 34.55 | 1.82 | 1.65 | 3.30 | 1.82 | 5.37 | 40 | 68 | 25000 | 24 | 96 | 98 | 89 | ||||||||||||||
75 | IgG1 | 3a | 2.49e-09 | 1.18e-09 | 1.27e-07 | 3.92e-10 | 8.85e-08 | 9650.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 379 | 3034 | 689 | 3668 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | strong | moderate | weak | weak | moderate | moderate | 6.13 | 6.1 | 5.8 | 6.2 | 5.09 | 4.88 | 5.15 | 6.25 | 91.3 | 1.68 | 35.65 | 1.88 | 2.00 | 4.00 | 1.45 | 4.25 | 63 | 93 | 25000 | 64 | 94 | 96 | 94 | ||||||||||||||||
76 | IgG1 | 3a | 3.62e-09 | 1.46e-09 | 1.77e-07 | 9.63e-10 | 5.26e-08 | 17600.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 3548 | 11060 | 2214 | 10897 | 2.50e+04 | 2.50e+04 | moderate | moderate | moderate | weak | weak | moderate | weak | 5.99 | 6.03 | 5.71 | 6.08 | 4.5 | 4.42 | 5.13 | 6.11 | 92.6 | 2.7 | 20.25 | 1.07 | 1.70 | 3.40 | 0.81 | 2.40 | 67 | 91 | 25000 | 60 | 93 | 95 | 80 | |||||||||||||||||
77 | IgG1 | 3a | 4.34e-09 | 1.79e-09 | 3.86e-07 | 1.07e-09 | 24600.0 | >25000 | >25000 | >25000 | >25000 | >25000 | 833.0 | 1010.0 | 1070.0 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | weak | moderate | strong | weak | moderate | moderate | 5.83 | 5.82 | 5.25 | 5.54 | 3.5 | 3.94 | 4.89 | 5.53 | 78.3 | 1.31 | 21.05 | 1.11 | 2.21 | 4.42 | 0.87 | 2.56 | 81 | 100 | 833 | 79 | 91 | 93 | 90 | |||||||||||||||||||||
78 | IgG1 | 5a | 7.18e-10 | 1.87e-10 | 3.93e-07 | 1.35e-10 | 74.2 | 224.0 | 663.0 | 44.9 | 164.0 | 519.0 | >25000 | >25000 | >25000 | 12 | 44 | 10 | 33 | 4.61e+01 | 8.75e+02 | 4.90e+03 | 100.0 | strong | weak | moderate | strong | weak | moderate | moderate | 6.23 | 6.21 | 5.91 | 6.32 | 5.5 | 5.57 | 5.57 | 6.44 | 48.7 | 2.42 | del68-69,V70I | 0.5mg/kg: 285.14|1.5mg/kg: 1432.71 | 38.55 | 2.03 | 1.95 | 3.90 | 1.49 | 4.37 | 17 | 38 | 25000 | 18 | 89 | 96 | 88 | F | |||||||||||||
79 | IgG1 | 2a | 8.78e-11 | 6.21e-11 | 7.45e-10 | 2.89e-07 | 3.51e-10 | 1.01e-08 | 53.7 | 140.0 | 235.0 | 315.0 | >25000 | >25000 | 39.1 | 80.6 | 129.0 | 0.38 | 3 | 379 | 747 | 2.38e+01 | 1.76e+02 | 5.68e+02 | 10.0 | strong | strong | strong | strong | moderate | moderate | moderate | 6.36 | 6.3 | 6.02 | 6.43 | 5.64 | 5.9 | 5.43 | 6.55 | 99.1 | 2.93 | 1.5mg/kg: 8009.08 | 31.95 | 1.69 | 1.73 | 3.45 | 2.31 | 6.78 | 1 | 34 | 39.1 | 1 | 32 | 38 | 37 | H1 | ||||||||||||
80 | IgG1 | 3a | 2.18e-09 | 1.21e-09 | 1.04e-07 | 5.09e-10 | 792.0 | 3340.0 | 7600.0 | 371.0 | 3670.0 | >25000 | 232.0 | 1270.0 | >25000 | 222 | 1595 | 978 | 3872 | 3.58e+03 | 8.52e+03 | 1.42e+04 | 0.0 | strong | moderate | moderate | strong | weak | moderate | moderate | 6.17 | 6.18 | 5.88 | 6.27 | 5.45 | 5.36 | 5.37 | 6.37 | 93.7 | 1.98 | 1.5mg/kg: 2316.58 | 31.85 | 1.68 | 1.46 | 2.91 | 1.27 | 3.75 | 52 | 64 | 232 | 27 | 81 | 81 | 76 | |||||||||||||||
81 | IgG1 | 3a | 1.47e-09 | 8.4e-10 | 9.88e-08 | 1.52e-10 | 7.16e-08 | 824.0 | 4140.0 | 9950.0 | 1390.0 | >25000 | >25000 | 227.0 | >25000 | >25000 | 100 | 627 | 268 | 736 | 4.31e+03 | 1.24e+04 | 2.30e+04 | 0.0 | strong | moderate | moderate | moderate | weak | moderate | weak | 6.19 | 6.13 | 5.85 | 6.24 | 5.28 | 5.16 | 5.26 | 6.3 | 86.8 | 3.09 | 0.5mg/kg: 397.89|1.5mg/kg: 1106.86 | 24.85 | 1.31 | 2.05 | 4.10 | 0.60 | 1.78 | 54 | 75 | 227 | 39 | 93 | 83 | 73 | B | |||||||||||||
82 | IgG1 | 7b | 1.28e-09 | 1.9e-09 | 3.61e-08 | 1.02e-09 | 3.29e-08 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 1950.0 | 3020.0 | 3360.0 | 20205 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 0.0 | strong | weak | weak | weak | weak | moderate | moderate | 6.04 | 6.01 | 5.61 | 5.94 | 4.02 | 4.12 | 5.03 | 5.8 | 33.1 | 3.82 | 1.5mg/kg: 1030.22 | 27.35 | 1.44 | 1.12 | 2.24 | 1.23 | 3.60 | 87 | 100 | 1950 | 83 | 96 | 81 | 77 | ||||||||||||||
83 | 7a | 3.73e-10 | 2.14e-10 | 8.94e-08 | 6.75e-11 | 4.35e-08 | 1030.0 | 3200.0 | 6030.0 | 335.0 | 1140.0 | 1700.0 | 380.0 | >25000 | >25000 | 99 | 396 | 172 | 503 | 2.50e+03 | 2.90e+03 | 3.16e+03 | 10.0 | strong | weak | moderate | moderate | weak | moderate | moderate | 6.3 | 6.22 | 5.94 | 6.28 | 5.04 | 5.1 | 5.29 | 6.26 | 98.0 | 3.84 | 0.5mg/kg: 1033.55|1.5mg/kg: 9035.08 | 43.85 | 2.31 | 1.82 | 3.65 | 1.62 | 4.76 | 44 | 36 | 380 | 8 | 100 | 90 | 77 | B | ||||||||||||||
84 | 7a | 4.33e-10 | 2.78e-10 | 9.29e-08 | 6.99e-11 | 1.62e-08 | 1570.0 | 4380.0 | 7700.0 | 374.0 | 1440.0 | 2000.0 | 569.0 | 2190.0 | 5470.0 | 49 | 175 | 225 | 573 | 1.27e+03 | 2.07e+03 | 2.75e+03 | 0.0 | strong | weak | moderate | weak | weak | moderate | moderate | 6.31 | 6.23 | 5.95 | 6.32 | 5.04 | 5.12 | 5.31 | 6.31 | 96.2 | 1.36 | E654A|R408G | 1.5mg/kg: 9120.49 | 25.15 | 1.33 | 0.93 | 1.85 | 2.26 | 6.65 | 53 | 46 | 569 | 10 | 100 | 92 | 87 | A | |||||||||||||
85 | IgG1 | 3a | 2.59e-09 | 8.04e-10 | 1.51e-07 | 2.71e-10 | 1.25e-07 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 284 | 786 | 429 | 1762 | 9.62e+03 | 3.59e+04 | 7.77e+04 | strong | moderate | moderate | weak | weak | moderate | moderate | 6.07 | 6.09 | 5.73 | 6.12 | 4.79 | 4.63 | 5.28 | 6.06 | 93.2 | 3.81 | 44.55 | 2.35 | 1.95 | 3.90 | 1.45 | 4.26 | 57 | 96 | 25000 | 58 | 100 | 100 | 100 | A | ||||||||||||||||||
86 | IgG1 | 2.16e-09 | 4.41e-10 | 1.03e-07 | 3.15e-10 | 1.03e-07 | 6150.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 691 | 4356 | 1.68e+04 | 4.58e+04 | 8.24e+04 | moderate | moderate | moderate | weak | weak | moderate | moderate | 6.21 | 6.18 | 5.92 | 6.3 | 5.38 | 5.42 | 5.32 | 6.39 | 96.8 | 2.05 | 36.45 | 1.92 | 2.13 | 4.26 | 1.18 | 3.46 | 65 | 94 | 25000 | 62 | 90 | 100 | 96 | A | ||||||||||||||||
87 | IgG4 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | weak | moderate | weak | weak | weak | moderate | weak | 4.0 | 3.79 | 3.62 | 3.71 | 3.46 | 3.9 | 4.91 | 4.65 | 8.2 | 1.22 | 30.20 | 1.59 | 1.80 | 3.60 | 1.15 | 3.38 | ||||||||||||||||||||||||||||||||||
88 | IgG1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
89 | IgG1 | 1 | 1.22e-09 | 5.64e-10 | 6.73e-08 | 1.49e-10 | 2.81e-09 | 536.0 | 2130.0 | 4470.0 | 412.0 | 1450.0 | 2380.0 | 82.5 | 406.0 | >25000 | 417 | 1117 | 4.46e+03 | 2.17e+04 | 5.46e+04 | 0.0 | weak | moderate | weak | weak | weak | moderate | moderate | 6.07 | 6.24 | 5.73 | 5.62 | 5.42 | 3.93 | 4.13 | 5.21 | 60.9 | 1.44 | 1.5mg/kg: 114.40 | 31.75 | 1.68 | 1.60 | 3.20 | 1.72 | 5.06 | nt | nt | nt | nt | nt | nt | nt | ||||||||||||||||
90 | IgG1 | 2c | 2.93e-10 | 1.27e-10 | 1.1e-07 | 1.86e-09 | 380.0 | 1190.0 | 2110.0 | 1040.0 | 1520.0 | 1670.0 | >25000 | >25000 | >25000 | 218 | 1357 | 1.89e+03 | 4.31e+03 | 6.98e+03 | moderate | weak | moderate | strong | weak | moderate | moderate | 6.33 | 6.26 | 5.97 | 6.38 | 5.53 | 5.74 | 5.59 | 6.49 | 100.0 | 1.57 | 26.25 | 1.39 | 1.67 | 3.34 | 0.80 | 2.35 | 32 | 100 | 25000 | 68 | 100 | 100 | 100 | H3 | ||||||||||||||||||
91 | IgG1 | 4c | 2.43e-10 | 5.69e-10 | 4.69e-09 | 4.46e-06 | 6.46e-10 | 3.48e-09 | 327.0 | 1660.0 | 4940.0 | 814.0 | 1220.0 | 1350.0 | >25000 | >25000 | >25000 | 66 | 680 | 4846 | 10146 | 2.50e+04 | 2.50e+04 | 2.50e+04 | None | strong | weak | strong | strong | moderate | moderate | moderate | 6.26 | 6.23 | 5.91 | 6.34 | 5.48 | 5.57 | 5.53 | 6.39 | 21.7 | 3.92 | 0.5mg/kg: 1375.38 | 49.40 | 2.61 | 1.06 | 2.13 | 1.41 | 4.13 | 61 | 100 | 25000 | 80 | 76 | 90 | 90 | G | ||||||||||||
92 | IgG1 | 2c | 1.04e-09 | 5.73e-10 | 1.96e-07 | 208.0 | 521.0 | 918.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 144 | 368 | 5.92e+02 | 1.03e+03 | 1.43e+03 | strong | moderate | moderate | moderate | weak | moderate | moderate | 6.12 | 6.08 | 5.8 | 6.18 | 3.8 | 5.13 | 5.23 | 6.17 | 91.2 | 1.49 | 51.95 | 2.74 | 1.33 | 2.66 | 1.75 | 5.15 | 26 | 100 | 25000 | 78 | 97 | 100 | 100 | ||||||||||||||||||||
93 | IgG2 | 1 | 1.02e-10 | 2.7e-11 | 4.31e-10 | 6.52e-07 | 2.02e-11 | 5.53e-10 | 69.3 | 225.0 | 407.0 | 26.9 | 89.8 | 199.0 | 26.2 | 70.1 | 138.0 | >25000 | >25000 | 7.05e+01 | 9.92e+01 | 1.21e+02 | 0.0 | moderate | weak | strong | strong | weak | moderate | moderate | 6.37 | 6.32 | 5.99 | 3.8 | 5.77 | 4.36 | 4.73 | 4.56 | 95.4 | 1.43 | R685S | 0.5mg/kg: 66.10|1.5mg/kg: 295.85 | 24.60 | 1.30 | 1.50 | 3.00 | 0.62 | 1.82 | 3 | 4 | 26.2 | 1 | 2 | 2 | 1 | B | |||||||||||||
94 | IgG1 | 4a | 1.04e-10 | 1.1e-10 | 5.62e-09 | 4.35e-11 | 2.77e-11 | 35.2 | 96.8 | 167.0 | 16.2 | 42.7 | 73.1 | >25000 | >25000 | >25000 | 4 | 8 | 2 | 6 | 8.87e+01 | 1.38e+02 | 1.79e+02 | 90.0 | moderate | moderate | weak | weak | weak | weak | weak | 6.18 | 6.19 | 5.84 | 6.08 | 4.29 | 4.6 | 5.42 | 6.02 | 98.0 | 1.64 | 0.5mg/kg: 2121.07|1.5mg/kg: 7219.93 | 34.20 | 1.80 | 1.60 | 3.20 | 1.05 | 3.10 | 1 | 11 | 25000 | 81 | 0 | 1 | 1 | H1 | |||||||||||||
95 | IgG1 | 4a | 8.41e-11 | 4.88e-11 | 2.75e-08 | 2.51e-10 | 3.28e-10 | 21.2 | 63.8 | 122.0 | >25000 | >25000 | >25000 | 24.2 | 6.69 | 3.65 | 0.34 | 1 | 798 | 14 | 1.24e+02 | 3.45e+02 | 6.26e+02 | None | strong | moderate | weak | weak | weak | moderate | moderate | 6.18 | 6.12 | 5.69 | 6.07 | 4.3 | 4.49 | 5.02 | 6.15 | 98.8 | 1.93 | 0.5mg/kg: 2508.19 | 24.90 | 1.31 | 1.35 | 2.70 | 0.52 | 1.53 | 10 | 99 | 24.2 | 96 | 5 | 7 | 13 | G | |||||||||||||
96 | IgG1 | 5a | 7.65e-11 | 5.66e-11 | 9.22e-08 | 4.7e-11 | 21.3 | 59.4 | 112.0 | 15.5 | 78.9 | 191.0 | 27.7 | 114.0 | 267.0 | <0.32 | 6 | 0.51 | 11 | 5.77e+01 | 1.76e+02 | 3.38e+02 | None | moderate | weak | weak | moderate | weak | moderate | strong | 6.02 | 6.18 | 5.41 | 6.01 | 4.99 | 4.16 | 5.09 | 6.24 | 44.8 | 1.26 | G339C | 0.5mg/kg: 1912.34 | 3 | 25 | 27.7 | 10 | 100 | 100 | 94 | F | |||||||||||||||||||
97 | IgG1 | 1 | 1.31e-11 | 6.31e-12 | 4.96e-09 | 3.41e-06 | 1.31e-11 | 6.2e-09 | 6.35 | 19.1 | 33.5 | 6.8 | 32.1 | 75.1 | 3.02 | 9.83 | 17.7 | <0.32 | 1 | <0.32 | 6 | 8.25e+01 | 1.41e+02 | 1.93e+02 | 30.0 | 100.0 | 1.4 | 0.5mg/kg: 5702.68 | 0 | 5 | 3.02 | 0 | 85 | 97 | 93 | H2 | |||||||||||||||||||||||||||||||||
98 | IgG1 | 1 | 7.35e-11 | 6.51e-11 | 3.82e-09 | 4.23e-11 | 2.66e-09 | 130.0 | 416.0 | 764.0 | 26.9 | 131.0 | 378.0 | 50.1 | 169.0 | 330.0 | 18 | 66 | 2 | 14 | 2.89e+02 | 4.28e+02 | 5.38e+02 | 10.0 | strong | moderate | weak | strong | weak | strong | moderate | 6.07 | 6.06 | 5.37 | 6.06 | 4.32 | 4.17 | 5.07 | 6.11 | 98.5 | 1.67 | 0.5mg/kg: 1495.80|1.5mg/kg: 4438.01 | 0 | 3 | 50.1 | 0 | 65 | 78 | 80 | B | |||||||||||||||||||
99 | IgG1 | 2c | 4.03e-11 | 2.13e-11 | 2.47e-09 | 1.42e-06 | 1.37e-08 | 13.8 | 35.8 | 60.1 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | <0.32 | <0.32 | 1605 | 3436 | 8.36e+01 | 1.51e+02 | 2.14e+02 | 10.0 | strong | moderate | moderate | moderate | weak | moderate | moderate | 6.28 | 6.16 | 5.95 | 6.13 | 4.96 | 5.37 | 5.33 | 6.22 | 100.0 | 1.55 | 0.5mg/kg: 2091.21|1.5mg/kg: 7010.57 | 1 | 96 | 25000 | 8 | 100 | 96 | 82 | H3 | |||||||||||||||||||
100 | IgG1 | 2b | 1.45e-11 | 8.37e-12 | 3.3e-09 | 1.61e-06 | 1.44e-11 | 3.66e-09 | 7.45 | 18.1 | 29.7 | 14.0 | 65.6 | 165.0 | 2.87 | 10.4 | 21.8 | 1 | 3 | 9 | 29 | 1.82e+01 | 2.93e+01 | 3.87e+01 | 80.0 | strong | strong | moderate | moderate | weak | moderate | strong | 6.28 | 6.13 | 6.05 | 6.19 | 5.07 | 5.56 | 5.21 | 6.27 | 100.0 | 2.19 | 0.5mg/kg: 3457.40|1.5mg/kg: 12740.40 | 0 | 5 | 2.87 | 0 | 54 | 73 | 69 | H2 | ||||||||||||||||||
101 | IgG1 | 4b | 2.99e-11 | 2.26e-11 | 3.94e-09 | 2.7e-11 | 6.43e-11 | 11.3 | 27.7 | 45.2 | 6.3 | 20.1 | 36.8 | 8.52 | 45.0 | 96.2 | 6 | 21 | 9 | 22 | 9.78e+01 | 2.27e+02 | 3.72e+02 | 90.0 | strong | moderate | weak | moderate | weak | strong | strong | 6.26 | 6.19 | 6.02 | 6.11 | 5.09 | 5.68 | 5.58 | 6.27 | 100.0 | 2.7 | S494L | 0.5mg/kg: 2611.60|1.5mg/kg: 10051.28 | 0 | 0 | 8.52 | 2 | 51 | 99 | 1 | G | ||||||||||||||||||
102 | 2b | 1.43e-10 | 6.77e-11 | 1.45e-09 | 4.98e-07 | 3.59e-11 | 5.78 | 15.8 | 27.0 | 4.47 | 10.6 | 17.1 | 2.81 | 7.3 | 10.2 | <0.32 | <0.32 | <0.32 | <0.32 | 2.16e+00 | 1.06e+01 | 2.67e+01 | 0.0 | weak | weak | weak | weak | weak | weak | weak | 3.84 | 3.91 | 3.64 | 3.33 | 4.22 | 3.8 | 4.63 | 4.25 | 84.3 | 1.3 | 0.5mg/kg: 50.30|1.5mg/kg: 50.30 | 19.05 | 1.07 | 1.21 | 1.13 | 0.49 | 1.88 | ||||||||||||||||||||||
103 | 2b | 8.34e-11 | 1.22e-10 | 1.62e-09 | 4.77e-07 | 5.37e-11 | 3.25e-10 | 8.82 | 24.4 | 42.6 | >25000 | >25000 | 20.0 | >25000 | 13.6 | 26.1 | <0.32 | <0.32 | <0.32 | <0.32 | 2.17e+01 | 4.28e+01 | 6.38e+01 | weak | weak | weak | weak | weak | weak | weak | 3.83 | 3.71 | 3.62 | 3.36 | 4.17 | 3.76 | 4.69 | 4.27 | 84.9 | 1.21 | 24.45 | 1.37 | 1.12 | 1.05 | 0.48 | 1.85 | |||||||||||||||||||||||
104 | 2b | 9.36e-11 | 8.39e-11 | 1.37e-09 | 6.74e-11 | 5.15e-10 | 16.8 | 26.2 | 33.8 | 60.2 | 204.0 | 444.0 | 264.0 | 631.0 | 1060.0 | <0.32 | <0.32 | 3 | 7 | 4.42e+00 | 6.57e+00 | 8.28e+00 | weak | weak | weak | weak | moderate | weak | weak | 3.8 | 3.74 | 3.63 | 3.33 | 4.22 | 3.78 | 4.78 | 4.24 | 86.1 | 1.22 | 23.20 | 1.30 | 1.56 | 1.46 | 0.36 | 1.38 | ||||||||||||||||||||||||
105 | IgG1 | 2d | 2.15e-11 | 1.26e-11 | 1.62e-08 | 5.44e-10 | 335.0 | 876.0 | 1520.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 23 | 68 | >25000 | >25000 | 1.86e+02 | 1.95e+02 | 2.00e+02 | moderate | moderate | moderate | moderate | weak | moderate | weak | 6.27 | 6.19 | 6.01 | 6.14 | 4.36 | 5.63 | 5.38 | 6.25 | 100.0 | 1.45 | Q493H,R685S | 16.35 | 0.92 | 1.37 | 1.28 | 0.24 | 0.94 | 15 | 99 | 25000 | 86 | 93 | 97 | 94 | H3 | |||||||||||||||
106 | IgG1 | 2d | 1.3e-11 | 6.62e-12 | 9.24e-10 | 2.79e-07 | 3.66e-10 | 6.85 | 18.4 | 31.3 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | <0.32 | 2 | 864 | 2686 | 1.34e+00 | 2.12e+00 | 2.78e+00 | None | moderate | strong | moderate | weak | weak | weak | weak | 6.3 | 6.14 | 5.99 | 6.19 | 4.82 | 5.55 | 5.42 | 6.25 | 100.0 | 1.66 | S494L | 0.5mg/kg: 4633.30 | 0 | 100 | 25000 | 80 | 85 | 94 | 94 | H3 | ||||||||||||||||||
107 | IgG1 | 2d | 2.23e-11 | 1e-11 | 9.39e-10 | 2.26e-07 | 3.61e-10 | 1.56e-07 | 8.2 | 28.9 | 54.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | <0.32 | 1 | 302 | 889 | 2.02e+01 | 2.78e+01 | 3.36e+01 | None | strong | strong | moderate | moderate | weak | moderate | moderate | 6.31 | 6.22 | 6.07 | 6.18 | 5.19 | 5.62 | 5.41 | 6.27 | 100.0 | 2.09 | E406D,S494P | 0.5mg/kg: 3584.13 | 38.45 | 2.15 | 1.20 | 1.12 | 0.56 | 2.15 | 0 | 100 | 25000 | 80 | 90 | 100 | 96 | H3 | |||||||||||
108 | IgG1 | 2d | 2.28e-11 | 1.09e-11 | 1.04e-09 | 3.6e-07 | 4.66e-10 | 1.15e-07 | 12.3 | 35.1 | 62.6 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2 | 5 | 4915 | 25000 | 2.55e+01 | 4.70e+01 | 6.73e+01 | None | strong | strong | moderate | strong | weak | moderate | moderate | 6.3 | 6.18 | 6.02 | 6.22 | 5.08 | 5.66 | 5.28 | 6.26 | 100.0 | 1.61 | R685S | 0.5mg/kg: 3066.01 | 18.80 | 1.05 | 1.56 | 1.46 | 0.34 | 1.29 | 97 | 100 | 25000 | 91 | 99 | 100 | 100 | H3 | |||||||||||
109 | IgG1 | 2d | 1.63e-11 | 1.06e-11 | 5.8e-10 | 1.96e-07 | 3.86e-10 | 3.59e-08 | 14.5 | 32.5 | 51.4 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 1 | 1 | 5666 | 18558 | 1.88e+01 | 2.58e+01 | 3.10e+01 | strong | strong | moderate | strong | weak | moderate | strong | 6.27 | 6.16 | 5.99 | 6.1 | 4.65 | 5.41 | 5.22 | 6.25 | 100.0 | 1.65 | 24.20 | 1.36 | 1.23 | 1.15 | 0.66 | 2.52 | 95 | 96 | 25000 | 100 | 100 | 100 | 90 | H3 | ||||||||||||||
110 | IgG1 | 2d | 2.26e-11 | 7.08e-12 | 1.53e-09 | 7.53e-07 | 6.18e-10 | 1.4e-07 | 18.0 | 49.5 | 88.6 | >25000 | >25000 | >25000 | 2000.0 | 2040.0 | 2050.0 | 2 | 6 | 19149 | >25000 | 1.91e+01 | 3.97e+01 | 6.10e+01 | strong | moderate | moderate | strong | weak | strong | strong | 6.3 | 6.23 | 6.09 | 6.18 | 5.06 | 5.58 | 5.3 | 6.28 | 100.0 | 1.9 | 48.90 | 2.74 | 1.32 | 1.24 | 1.15 | 4.42 | 1 | 93 | 2000 | 79 | 97 | 89 | 87 | H3 | ||||||||||||||
111 | IgG1 | 2d | 2.02e-11 | 1.01e-11 | 1.39e-09 | 3.84e-07 | 3.94e-10 | 5.42e-08 | 17.3 | 44.0 | 74.2 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 15 | 31 | 16200 | >25000 | 6.71e+01 | 8.75e+01 | 1.02e+02 | None | strong | moderate | moderate | strong | weak | strong | strong | 6.29 | 6.2 | 6.07 | 6.19 | 5.01 | 5.6 | 5.5 | 6.29 | 100.0 | 1.77 | 0.5mg/kg: 3120.30 | 33.10 | 1.85 | 1.32 | 1.24 | 0.66 | 2.52 | 0 | 85 | 25000 | 80 | 92 | 90 | 82 | H3 | ||||||||||||
112 | IgG1 | 2d | 1.78e-11 | 9.16e-12 | 3.46e-10 | 1.23e-07 | 3.09e-10 | 4.14e-08 | 10.1 | 26.4 | 44.2 | >25000 | >25000 | >25000 | 0.976 | >25000 | >25000 | 3 | 14 | 8465 | 23584 | 2.53e+01 | 3.77e+01 | 4.76e+01 | None | moderate | strong | moderate | strong | weak | strong | strong | 6.25 | 6.18 | 6.01 | 6.12 | 4.88 | 5.5 | 5.38 | 6.27 | 100.0 | 1.85 | S494P|S494L | 0.5mg/kg: 1062.27 | 46.45 | 2.60 | 1.14 | 1.06 | 1.28 | 4.92 | 0 | 85 | 0.976 | 44 | 89 | 90 | 73 | H3 | |||||||||||
113 | IgG1 | 7c | 3.71e-10 | 2.5e-10 | 1.37e-09 | 1.48e-10 | 2.79e-09 | 9750.0 | >25000 | >25000 | 2140.0 | 5390.0 | 8490.0 | 3580.0 | 9210.0 | 11700.0 | 1846 | 6065 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | moderate | weak | strong | weak | moderate | moderate | 6.06 | 6.11 | 5.48 | 6.03 | 4.35 | 4.54 | 4.12 | 6.09 | 27.2 | 1.41 | 38.90 | 2.18 | 0.98 | 0.92 | 0.96 | 3.71 | 85 | 88 | 3580 | 83 | 85 | 92 | 87 | C3 | |||||||||||||||||
114 | IgG1 | 7c | 3.53e-10 | 2.21e-10 | 6.2e-10 | 7.49e-08 | 1.25e-10 | 2.08e-09 | 2660.0 | 8580.0 | 15700.0 | 1290.0 | 5380.0 | 7560.0 | >25000 | >25000 | >25000 | 120 | 1435 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | moderate | moderate | moderate | weak | moderate | moderate | 6.0 | 6.01 | 5.28 | 5.98 | 4.26 | 4.28 | 4.85 | 6.05 | 31.1 | 1.96 | 16.15 | 0.90 | 1.30 | 1.21 | 0.40 | 1.52 | 78 | 81 | 25000 | 64 | 84 | 90 | 81 | C3 | ||||||||||||||||
115 | IgG1 | 7c | 3.79e-10 | 2.43e-10 | 8.54e-10 | 3.57e-07 | 2.19e-10 | 2.99e-09 | 3410.0 | 11600.0 | 21200.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 965 | 2939 | 1.32e+04 | 2.78e+04 | 4.30e+04 | moderate | moderate | moderate | strong | weak | moderate | moderate | 6.05 | 6.06 | 5.27 | 6.0 | 4.28 | 4.45 | 4.83 | 6.07 | 34.5 | 1.54 | 37.70 | 2.11 | 1.04 | 0.97 | 0.56 | 2.13 | 85 | 89 | 25000 | 76 | 89 | 90 | 81 | C3 | ||||||||||||||||
116 | IgG1 | 5a | 9.11e-11 | 5.41e-11 | 1.03e-08 | 3.47e-11 | 2.55e-08 | 9.43 | 27.0 | 47.4 | 8.93 | 27.9 | 45.6 | 8.91 | 19.9 | 29.9 | 2 | 5 | <0.32 | <0.32 | 5.26e+01 | 7.77e+01 | 9.76e+01 | 90.0 | moderate | moderate | strong | strong | weak | weak | moderate | 6.03 | 5.87 | 5.47 | 5.9 | 4.25 | 4.37 | 4.92 | 6.03 | 29.2 | 2.1 | G339V|G339C|G339F | 0.5mg/kg: 667.65|1.5mg/kg: 2646.21 | 15.55 | 0.87 | 1.24 | 1.16 | 0.25 | 0.96 | 0 | 0 | 8.91 | 0 | 84 | 92 | 84 | F | ||||||||||||
117 | IgG1 | 4b | 1.29e-11 | 6.38e-12 | 9.06e-10 | 2.88e-07 | 3.53e-11 | 1.31e-11 | 7.32 | 16.9 | 27.3 | 561.0 | 2520.0 | 6210.0 | 7030.0 | >25000 | >25000 | 2 | 7 | 0.5 | 16 | 1.29e+01 | 1.51e+01 | 1.66e+01 | 80.0 | moderate | weak | moderate | weak | moderate | strong | moderate | 6.35 | 6.21 | 6.23 | 6.14 | 6.48 | 6.06 | 5.66 | 6.33 | 64.6 | 1.58 | 0.5mg/kg: 4081.89|1.5mg/kg: 9977.60 | 38.50 | 2.16 | 2.92 | 2.73 | 1.55 | 5.98 | 1 | 17 | 7030 | 42 | 1 | 72 | 1 | G | ||||||||||||
118 | IgG1 | 173.0 | 415.0 | 710.0 | >25000 | >25000 | >25000 | 102.0 | 622.0 | 1190.0 | 63 | 173 | 542 | 1823 | 2.24e+02 | 3.87e+02 | 5.32e+02 | 60.0 | moderate | strong | moderate | weak | weak | moderate | moderate | 6.31 | 6.12 | 6.15 | 6.18 | 5.28 | 5.88 | 5.8 | 6.32 | 100.0 | 2.33 | S371F | 0.5mg/kg: 1151.12|5mg/kg: 14018.21 | 38.95 | 2.18 | 0.90 | 0.84 | 1.10 | 4.23 | ||||||||||||||||||||||||||
119 | 7a | 1.16e-09 | 4.52e-10 | 1.79e-07 | 5.71e-11 | 2.69 | 8.7 | 16.5 | 0.907 | 3.5 | 8.08 | 2.03 | 6.23 | 12.7 | <0.32 | 3 | <0.32 | 4 | 1.71e+01 | 2.28e+01 | 2.70e+01 | weak | weak | weak | weak | moderate | weak | weak | 3.89 | 3.69 | 3.65 | 3.57 | 3.82 | 3.93 | 5.44 | 4.39 | 100.0 | 1.2 | 18.60 | 1.04 | 2.08 | 1.94 | 0.45 | 1.73 | 0 | 0 | 2.03 | 1 | 1 | 0 | 87 | C2 | |||||||||||||||||
120 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
121 | 7a | 1.06e-09 | 4.29e-10 | 1.95e-07 | 3.75e-11 | 2.2 | 8.02 | 16.1 | 0.637 | 2.13 | 3.93 | 0.431 | 2.34 | 5.71 | <0.32 | <0.32 | 0.64 | 2 | 1.79e+01 | 3.82e+01 | 5.96e+01 | weak | weak | weak | strong | weak | weak | weak | 3.87 | 3.67 | 3.68 | 3.58 | 3.81 | 3.95 | 4.81 | 4.38 | 99.5 | 1.16 | 21.75 | 1.22 | 1.67 | 1.56 | 0.73 | 2.81 | 0 | 0 | 0.431 | 0 | 1 | 1 | 95 | C2 | |||||||||||||||||
122 | 7a | 9.01e-10 | 6.01e-10 | 2.03e-07 | 4.09e-11 | 2.1 | 7.32 | 14.4 | 1.31 | 5.67 | 12.6 | 1.09 | 3.74 | 7.89 | 2 | 8 | <0.32 | 3 | 3.98e+01 | 1.44e+02 | 3.06e+02 | weak | weak | weak | weak | weak | weak | weak | 3.84 | 3.7 | 3.67 | 3.61 | 3.81 | 3.95 | 4.85 | 4.36 | 97.9 | 0.684 | 21.90 | 1.23 | 1.20 | 1.12 | 2.00 | 7.71 | 0 | 0 | 1.09 | 0 | 1 | 1 | 85 | C2 | |||||||||||||||||
123 | 7a | 1.33e-09 | 4.06e-10 | 2.06e-07 | 3.68e-11 | 1.08 | 3.17 | 5.97 | 0.51 | 1.74 | 3.55 | 0.179 | 0.731 | 1.46 | <0.32 | <0.32 | <0.32 | 0.96 | 1.82e+01 | 1.17e+02 | 3.49e+02 | 0.0 | weak | weak | weak | weak | weak | moderate | weak | 3.88 | 3.71 | 3.67 | 3.58 | 3.84 | 3.94 | 5.14 | 4.37 | 97.6 | 2.03 | 1.5mg/kg: 50.30 | 22.70 | 1.27 | 1.49 | 1.39 | 0.44 | 1.69 | 0 | 0 | 0.179 | 0 | 1 | 1 | 78 | C2 | |||||||||||||||
124 | 7a | 9.46e-10 | 5.39e-10 | 1.67e-07 | 3.76e-11 | 0.893 | 2.82 | 5.31 | 0.678 | 2.69 | 5.87 | 0.631 | 2.14 | 4.16 | <0.32 | 0.92 | <0.16 | <0.16 | 1.82e+01 | 3.46e+01 | 5.02e+01 | 0.0 | weak | weak | weak | weak | weak | weak | weak | 3.88 | 3.7 | 3.69 | 3.57 | 3.81 | 3.93 | 5.59 | 4.39 | 98.3 | 1.36 | 0.5mg/kg: 50.30|1.5mg/kg: 50.30 | 19.80 | 1.11 | 1.73 | 1.61 | 0.34 | 1.31 | 0 | 0 | 0.631 | 2 | 1 | 1 | 82 | C2 | |||||||||||||||
125 | 7a | 1.6e-09 | 4.99e-10 | 1.84e-07 | 6.42e-11 | 2.02 | 6.44 | 12.1 | 1.93 | 4.88 | 8.89 | 1.76 | 6.76 | 14.2 | 1 | 1 | <0.32 | 5 | 4.12e+01 | 4.52e+01 | 4.77e+01 | weak | weak | weak | strong | weak | moderate | weak | 3.86 | 3.68 | 3.65 | 3.56 | 3.83 | 3.94 | 5.52 | 4.42 | 98.8 | 1.14 | 24.90 | 1.39 | 1.56 | 1.46 | 0.88 | 3.37 | 0 | 0 | 1.76 | 0 | 1 | 0 | 75 | C2 | |||||||||||||||||
126 | 7a | 9.42e-10 | 3.95e-10 | 1.39e-07 | 6.06e-11 | 2.02 | 6.34 | 11.9 | 1.92 | 7.37 | 15.4 | 0.245 | 7.11 | 23.0 | 0.35 | 1 | <0.32 | 0.84 | 1.97e+01 | 6.74e+01 | 1.39e+02 | weak | weak | weak | moderate | weak | weak | weak | 3.85 | 3.69 | 3.65 | 3.56 | 3.81 | 3.94 | 5.44 | 4.46 | 98.5 | 2.58 | 19.80 | 1.11 | 1.90 | 1.78 | 0.50 | 1.92 | 0 | 0 | 0.245 | 0 | 0 | 0 | 88 | C2 | |||||||||||||||||
127 | IgG1 | 7a | 1.81e-09 | 9.03e-10 | 1.06e-07 | 5.01e-11 | 2.77 | 10.8 | 23.0 | >25000 | >25000 | >25000 | 1.92 | 7.64 | 16.7 | 1 | 2 | 0.34 | 3 | 4.04e+01 | 4.60e+01 | 4.97e+01 | 0.0 | strong | moderate | weak | moderate | moderate | strong | moderate | 5.96 | 5.95 | 5.57 | 5.96 | 5.64 | 4.28 | 5.77 | 5.88 | 98.6 | 2.68 | 0.5mg/kg: 50.30|1.5mg/kg: 50.30 | 29.75 | 1.67 | 1.65 | 1.54 | 0.94 | 3.63 | 0 | 0 | 1.92 | 0 | 1 | 1 | 79 | C2 | ||||||||||||||
128 | IgG1 | 7a | 3.6e-09 | 1.37e-09 | 1.19e-07 | 7.74e-11 | 5.58 | 18.3 | 34.4 | 2.66 | 11.2 | 22.8 | 2.84 | 9.37 | 19.3 | 7.40e+01 | 1.09e+02 | 1.37e+02 | 0.0 | strong | moderate | weak | weak | weak | strong | moderate | 6.17 | 6.1 | 5.71 | 6.11 | 5.95 | 5.11 | 5.05 | 6.12 | 98.6 | 2.82 | 0.5mg/kg: 50.30|1.5mg/kg: 50.30 | 28.75 | 1.61 | 1.10 | 1.03 | 1.34 | 5.15 | 1 | 0 | 2.84 | 0 | 6 | 9 | 72 | C3 | ||||||||||||||||||
129 | 7a | 1.25e-09 | 6.49e-10 | 1.35e-07 | 5.38e-11 | 1.98 | 7.46 | 15.9 | 1.59 | 5.95 | 12.3 | 0.936 | 2.98 | 4.85 | <0.32 | 1 | 8 | 17 | 3.36e+01 | 7.58e+01 | 1.22e+02 | 0.0 | weak | weak | weak | moderate | weak | weak | weak | 3.86 | 3.7 | 3.67 | 3.66 | 3.82 | 3.93 | 5.8 | 4.36 | 99.6 | 1.63 | 0.5mg/kg: 50.30|1.5mg/kg: 50.30 | 17.65 | 0.99 | 1.75 | 1.64 | 0.85 | 3.27 | 1 | 0 | 0.936 | 0 | 1 | 1 | 66 | C2 | |||||||||||||||
130 | <0.32 | <0.32 | <0.16 | <0.16 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
131 | IgG | 7c | 1.01e-09 | 3.78e-10 | 2.05e-09 | 9.09e-07 | 3.97e-10 | 8.82e-09 | 13600.0 | >25000 | >25000 | >25000 | >25000 | >25000 | 6560.0 | 11100.0 | 12700.0 | 1550 | 9937 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | moderate | weak | weak | weak | strong | weak | 6.15 | 6.09 | 5.66 | 6.01 | 3.82 | 3.94 | 4.85 | 6.17 | 14.6 | 2.1 | 47.60 | 2.67 | 0.90 | 0.84 | 0.92 | 3.52 | 75 | 90 | 6560 | 56 | 97 | 93 | 84 | C3 | ||||||||||||||||
132 | IgG | 9.83e-10 | 5.63e-10 | 2.18e-10 | 1.02e-09 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 0.0 | moderate | moderate | moderate | moderate | moderate | weak | weak | 5.84 | 5.85 | 5.25 | 5.67 | 3.83 | 3.93 | 4.82 | 5.87 | 2.5 | 1.67 | 1.5mg/kg: 8370.07 | 14.85 | 0.83 | 1.95 | 1.82 | 0.92 | 3.54 | 89 | 89 | 25000 | 70 | 100 | 98 | 91 | E3 | ||||||||||||||||||||
133 | IgG | 7.08e-10 | 1.23e-09 | 3.12e-08 | 1.12e-09 | 1.07e-08 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | moderate | strong | strong | weak | weak | moderate | 6.21 | 6.19 | 5.91 | 6.18 | 3.86 | 3.93 | 4.81 | 6.24 | 5.5 | 2.25 | 8.84 | 0.50 | 47 | 96 | 25000 | 52 | 96 | 96 | 90 | E3 | |||||||||||||||||||||||||
134 | IgG | 5a | 6.75e-10 | 3.5e-10 | 9e-08 | 3.66e-11 | 4.15e-09 | 48.2 | 161.0 | 317.0 | 22.9 | 79.8 | 162.0 | 21.4 | 61.7 | 110.0 | 16 | 48 | 11 | 69 | 1.90e+02 | 2.07e+02 | 2.18e+02 | 70.0 | strong | strong | moderate | strong | weak | moderate | moderate | 6.11 | 6.04 | 5.79 | 6.06 | 5.76 | 5.01 | 4.73 | 6.12 | 63.5 | 2.08 | 0.5mg/kg: 510.44|1.5mg/kg: 1800.11 | 32.80 | 1.84 | 1.07 | 1.00 | 0.69 | 2.63 | 3 | 8 | 21.4 | 3 | 72 | 97 | 82 | G | |||||||||||||
135 | IgG | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | None | weak | weak | moderate | strong | weak | weak | weak | 3.84 | 3.69 | 3.71 | 3.58 | 3.83 | 3.95 | 4.68 | 4.29 | 6.5 | 1.44 | 0.5mg/kg: 50.30 | 17.45 | 0.98 | 4.39 | 4.10 | 0.48 | 1.87 | 33 | 85 | 25000 | 22 | 54 | 81 | 79 | |||||||||||||||||||||||||
136 | IgG | 2a | 6.68e-10 | 3.33e-10 | 9.86e-09 | 3.44e-06 | 6.13e-09 | 77.7 | 231.0 | 427.0 | >25000 | >25000 | >25000 | 20.4 | 161.0 | 368.0 | 36 | 81 | >25000 | >25000 | 3.31e+02 | 6.01e+02 | 8.51e+02 | 10.0 | strong | moderate | moderate | strong | weak | moderate | moderate | 6.24 | 6.24 | 5.95 | 6.19 | 5.62 | 5.61 | 4.88 | 6.32 | 99.5 | 3.41 | 0.5mg/kg: 1172.77|1.5mg/kg: 3502.69 | 34.30 | 1.92 | 0.52 | 0.49 | 0.55 | 2.12 | 7 | 92 | 20.4 | 4 | 63 | 90 | 80 | H2 | |||||||||||||
137 | IgG | 1.84e-09 | 1.59e-09 | 1.15e-09 | 1.06e-09 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 0.0 | moderate | weak | moderate | moderate | weak | weak | weak | 6.08 | 6.07 | 5.72 | 6.02 | 3.81 | 3.93 | 4.74 | 6.11 | 1.77 | 1.5mg/kg: 50.30 | 26.45 | 1.48 | 1.91 | 1.78 | 0.67 | 2.58 | 61 | 91 | 25000 | 46 | 72 | 82 | 77 | E3 | |||||||||||||||||||||
138 | IgG | 5.28e-07 | 8.44e-10 | 3.74e-08 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | weak | moderate | strong | weak | weak | weak | 5.85 | 5.82 | 5.48 | 5.49 | 3.82 | 3.94 | 4.64 | 5.61 | 2.6 | 25.00 | 1.40 | 1.12 | 1.05 | 0.52 | 2.00 | 75 | 93 | 25000 | 44 | 73 | 91 | 65 | E3 | |||||||||||||||||||||
139 | IgG | 7b | 6.64e-10 | 2.12e-09 | 4.46e-08 | 2.17e-10 | 6.04e-08 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 0.0 | moderate | weak | moderate | moderate | weak | weak | weak | 6.14 | 6.2 | 5.73 | 6.13 | 3.84 | 3.94 | 4.69 | 6.15 | 63.9 | 1.59 | 1.5mg/kg: 2508.65 | 80 | 90 | 25000 | 67 | 66 | 100 | 71 | C3 | |||||||||||||||||||||
140 | IgG | 2d | 1.35e-10 | 7.66e-11 | 1.9e-07 | 181.0 | 621.0 | 1310.0 | >25000 | >25000 | >25000 | 159.0 | 881.0 | 1740.0 | 14 | 87 | >25000 | >25000 | 2.09e+03 | 7.80e+03 | 1.69e+04 | 70.0 | strong | moderate | moderate | strong | weak | strong | strong | 6.08 | 6.1 | 5.71 | 5.99 | 5.35 | 5.37 | 4.75 | 6.06 | 100.0 | 2.48 | 1.5mg/kg: 1045.49 | 36.45 | 2.04 | 0.97 | 0.91 | 0.80 | 3.08 | 23 | 95 | 159 | 23 | 80 | 93 | 65 | H3 | |||||||||||||||
141 | IgG | 2c | 2.53e-10 | 1.3e-10 | 1.07e-07 | 2470.0 | 9640.0 | 19800.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 107 | 281 | 1.43e+03 | 2.43e+03 | 3.31e+03 | 10.0 | moderate | moderate | moderate | strong | weak | strong | strong | 6.22 | 6.2 | 5.96 | 6.25 | 5.29 | 5.44 | 5.04 | 6.33 | 100.0 | 3.44 | 1.5mg/kg: 8654.62 | 45.20 | 2.53 | 1.34 | 1.26 | 1.25 | 4.83 | 26 | 95 | 25000 | 42 | 56 | 89 | 68 | H3 | |||||||||||||||||
142 | IgG | 2a | 2.92e-10 | 2.8e-10 | 1.65e-08 | 6.08e-10 | 8.16e-09 | 87.4 | 286.0 | 534.0 | 782.0 | 11300.0 | >25000 | 40.2 | 114.0 | 209.0 | 16 | 74 | >25000 | >25000 | 3.06e+02 | 5.50e+02 | 7.76e+02 | strong | moderate | moderate | strong | weak | moderate | moderate | 6.19 | 6.19 | 5.85 | 6.16 | 5.3 | 5.5 | 4.93 | 6.28 | 100.0 | 4.23 | 0.5mg/kg: 1642.16 | 44.80 | 2.51 | 2.10 | 1.96 | 2.56 | 9.83 | 8 | 99 | 40.2 | 1 | 60 | 57 | 64 | H2 | ||||||||||||||
143 | IgG | 1 | 3.82e-10 | 2.34e-10 | 5.91e-09 | 237.0 | 733.0 | 1660.0 | 426.0 | 1680.0 | 2380.0 | 39.8 | 136.0 | 258.0 | 8 | 36 | >25000 | >25000 | 7.92e+02 | 9.10e+02 | 9.87e+02 | 0.0 | strong | moderate | weak | moderate | weak | moderate | moderate | 6.17 | 6.2 | 5.91 | 6.14 | 5.67 | 5.33 | 5.04 | 6.37 | 100.0 | 2.42 | 0.5mg/kg: 6260.70 | 27.60 | 1.28 | 0.49 | 1.46 | 0.81 | 1.36 | 20 | 98 | 39.8 | 4 | 90 | 87 | 94 | B | |||||||||||||||
144 | IgG1 | 5a | 2.45e-10 | 1.09e-10 | 1.03e-10 | 3.21e-07 | 1.21e-10 | 2.86e-10 | 4.39 | 10.6 | 17.5 | 26.8 | 112.0 | 207.0 | 24.3 | 70.3 | 127.0 | 5 | 32 | 12 | 74 | 1.60e+02 | 2.54e+02 | 3.32e+02 | strong | strong | weak | moderate | moderate | strong | strong | 6.33 | 6.33 | 6.0 | 6.35 | 6.23 | 5.94 | 5.9 | 6.41 | 23.6 | 4.41 | 29.50 | 1.37 | 0.57 | 1.72 | 0.49 | 0.84 | 2 | 3 | 24.3 | 4 | 17 | 23 | 58 | E1 | ||||||||||||||
145 | IgG1 | 7a | 4.49e-10 | 1.5e-10 | 3.94e-08 | 4.99e-11 | 9.64e-09 | 12.6 | 52.6 | 114.0 | 30.7 | 264.0 | 663.0 | 21.9 | 95.6 | 213.0 | 10 | 38 | 24 | 100 | 1.13e+02 | 3.13e+02 | 5.67e+02 | 10.0 | moderate | weak | moderate | weak | moderate | weak | weak | 6.02 | 5.84 | 5.42 | 5.43 | 4.89 | 4.0 | 4.7 | 5.76 | 99.9 | 1.89 | 0.5mg/kg: 661.25|1.5mg/kg: 1907.98 | 24.20 | 1.12 | 0.54 | 1.61 | 0.56 | 0.95 | 0 | 2 | 21.9 | 0 | 56 | 62 | 94 | C3 | |||||||||||||
146 | IgG1 | 7.91e-10 | 5.76e-10 | 4.9e-10 | 1.73e-09 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | moderate | moderate | moderate | weak | weak | weak | 6.18 | 6.12 | 5.78 | 6.14 | 3.83 | 3.95 | 4.87 | 6.22 | 4.7 | 2.97 | 24.80 | 1.15 | 0.46 | 1.36 | 0.90 | 1.53 | 88 | 87 | 25000 | 96 | 88 | 92 | 92 | E3 | ||||||||||||||||||||||
147 | IgG1 | 2b | 1.93e-11 | 2.02e-11 | 2.3e-09 | 1.65e-06 | 1.83e-10 | 5.58e-09 | 5.84 | 14.6 | 24.0 | 404.0 | 2800.0 | 7360.0 | 1.25 | 4.97 | 8.95 | <0.32 | 1 | 3935 | 14040 | 1.08e+01 | 1.25e+01 | 1.36e+01 | 100.0 | strong | strong | moderate | strong | weak | moderate | moderate | 6.29 | 6.29 | 5.98 | 6.31 | 4.63 | 5.67 | 5.43 | 6.37 | 100.0 | 2.78 | G485D | 0.5mg/kg: 4483.43|1.5mg/kg: 16547.06 | 21.60 | 1.00 | 2.15 | 6.42 | 1.60 | 2.72 | 0 | 90 | 1.25 | 1 | 79 | 83 | 81 | H2 | |||||||||||
148 | IgG1 | 2d | 2.98e-11 | 1.02e-11 | 1.85e-09 | 1.36e-06 | 3.82 | 10.2 | 17.0 | 371.0 | 1180.0 | 1580.0 | 1.8 | 7.43 | 14.1 | <0.32 | 2 | >25000 | >25000 | 1.52e+01 | 2.61e+01 | 3.59e+01 | None | strong | strong | moderate | strong | weak | strong | strong | 6.3 | 6.22 | 5.98 | 6.22 | 4.08 | 5.6 | 5.39 | 6.35 | 100.0 | 2.94 | 0.5mg/kg: 6141.31 | 0 | 93 | 1.8 | 1 | 71 | 96 | 82 | B | ||||||||||||||||||||
149 | IgG1 | 5c | 5.94e-11 | 6.81e-11 | 2.23e-08 | 9.05e-12 | 6.56e-10 | 95.6 | 244.0 | 401.0 | 315.0 | 1550.0 | 3740.0 | 56.5 | 217.0 | 456.0 | 12 | 38 | 0.38 | 5 | 1.91e+02 | 5.08e+02 | 9.02e+02 | 100.0 | strong | strong | moderate | strong | weak | strong | moderate | 6.33 | 6.28 | 6.0 | 6.33 | 5.75 | 5.81 | 5.47 | 6.39 | 100.0 | 2.75 | A348E | 1.5mg/kg: 17131.97|5mg/kg: 54047.50 | 4 | 25 | 56.5 | 10 | 64 | 92 | 2 | G | ||||||||||||||||||
150 | IgG1 | 2a | 2.1e-09 | 7.7e-10 | 1.41e-07 | 1.31e-09 | 4.53e-08 | 331.0 | 981.0 | 1800.0 | 1630.0 | 9700.0 | 15600.0 | 90.0 | 364.0 | 664.0 | 171 | 342 | 2.44e+02 | 5.29e+02 | 8.32e+02 | 0.0 | strong | weak | moderate | strong | weak | weak | moderate | 6.21 | 6.19 | 5.81 | 6.12 | 3.86 | 5.43 | 4.91 | 6.21 | 100.0 | 2.51 | 1.5mg/kg: 1841.74 | 21.15 | 0.98 | 0.68 | 2.01 | 0.85 | 1.44 | 47 | 68 | 90 | 13 | 85 | 89 | 62 | H1 | |||||||||||||||
151 | IgG1 | 5b | 4.47e-10 | 6.79e-10 | 6.31e-09 | 2.91e-06 | 1.85e-10 | 7.1e-09 | 1310.0 | 4820.0 | 9330.0 | 601.0 | 2470.0 | 3640.0 | >25000 | >25000 | >25000 | 1817 | 5352 | 5398 | 19390 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 0.0 | moderate | moderate | weak | strong | weak | weak | weak | 6.25 | 6.27 | 5.91 | 6.26 | 3.84 | 3.98 | 4.9 | 6.27 | 46.2 | 1.88 | 1.5mg/kg: 6855.20 | 26.65 | 1.24 | 0.45 | 1.34 | 0.74 | 1.26 | 85 | 87 | 25000 | 79 | 76 | 93 | 59 | E4 | ||||||||||||
152 | IgG1 | 5b | 3.27e-10 | 1.37e-09 | 3.02e-09 | 1.82e-06 | 3.65e-10 | 6.63e-09 | 1750.0 | 7580.0 | 17000.0 | 383.0 | 1770.0 | 2540.0 | 1000.0 | 1020.0 | 1020.0 | 3671 | 7621 | 8896 | 22602 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | moderate | weak | strong | weak | weak | weak | 6.23 | 6.2 | 5.98 | 6.26 | 3.8 | 3.95 | 4.83 | 6.25 | 31.2 | 2.56 | 25.60 | 1.19 | 0.60 | 1.79 | 0.61 | 1.03 | 87 | 91 | 1000 | 92 | 69 | 96 | 68 | E4 | ||||||||||||||
153 | IgG1 | 2a | 5.05e-10 | 1.44e-10 | 2.06e-09 | 6.02e-07 | 3.8e-10 | 2.82e-08 | 28.8 | 87.0 | 157.0 | >25000 | >25000 | >25000 | 35.5 | 97.4 | 172.0 | 15 | 32 | >25000 | >25000 | 2.44e+02 | 3.85e+02 | 5.04e+02 | 30.0 | strong | moderate | weak | strong | weak | moderate | strong | 6.28 | 6.3 | 6.01 | 6.29 | 5.19 | 5.77 | 5.16 | 6.34 | 99.4 | 1.92 | S459P | 0.5mg/kg: 1358.37|1.5mg/kg: 5859.62 | 4 | 89 | 35.5 | 2 | 83 | 84 | 19 | H1 | |||||||||||||||||
154 | IgG1 | 3.35e-10 | 2.9e-10 | 8.16e-11 | 3.85e-10 | 328.0 | 807.0 | 1340.0 | 220.0 | 914.0 | 1820.0 | 135.0 | 494.0 | 797.0 | 190 | 544 | 1.80e+04 | 3.10e+04 | 4.25e+04 | 0.0 | moderate | moderate | weak | strong | weak | weak | weak | 6.08 | 6.06 | 5.78 | 6.0 | 3.81 | 4.0 | 4.8 | 6.06 | 2.4 | 2.13 | 0.5mg/kg: 50.30|1.5mg/kg: 1010.60|5mg/kg: 212.60 | 26.60 | 1.23 | 0.57 | 1.72 | 0.54 | 0.92 | 32 | 49 | 135 | 28 | 33 | 26 | 40 | E3 | |||||||||||||||||
155 | IgG1 | 2c | 3.38e-11 | 1.05e-10 | 8.42e-10 | 6.53e-07 | 8.4e-10 | 11.5 | 27.6 | 44.4 | >25000 | >25000 | >25000 | 22.7 | 56.9 | 94.6 | <0.32 | 3 | >25000 | >25000 | 6.46e+01 | 1.06e+02 | 1.41e+02 | 80.0 | strong | strong | weak | moderate | weak | strong | strong | 6.29 | 6.23 | 6.02 | 6.32 | 5.04 | 5.7 | 5.63 | 6.36 | 99.9 | 3.73 | F486E | 0.5mg/kg: 3751.21|1.5mg/kg: 12043.94 | 28.30 | 1.31 | 0.38 | 1.13 | 0.35 | 0.59 | 1 | 96 | 22.7 | 1 | 98 | 79 | 71 | B | ||||||||||||
156 | IgG1 | 2a | 4.77e-11 | 3.15e-11 | 4.46e-10 | 2.19e-07 | 9.71e-10 | 23.1 | 60.8 | 103.0 | >25000 | >25000 | >25000 | 22.7 | 60.5 | 104.0 | 2 | 9 | >25000 | >25000 | 1.52e+02 | 5.33e+02 | 1.11e+03 | None | strong | strong | weak | moderate | moderate | moderate | moderate | 6.33 | 6.27 | 6.04 | 6.33 | 4.36 | 5.8 | 5.09 | 6.38 | 97.9 | 2.56 | N481K,del482-484|N487T | 0.5mg/kg: 2633.21 | 27.35 | 1.27 | 0.43 | 1.28 | 0.51 | 0.86 | 1 | 91 | 22.7 | 1 | 94 | 98 | 94 | H1 | ||||||||||||
157 | IgG1 | 2a | 2.69e-10 | 6.43e-10 | 6.65e-09 | 2.32e-06 | 8.5e-09 | 39.8 | 101.0 | 171.0 | >25000 | >25000 | >25000 | 20.7 | 89.8 | 186.0 | 12 | 28 | >25000 | >25000 | 3.07e+02 | 4.71e+02 | 6.05e+02 | 40.0 | strong | strong | moderate | weak | weak | moderate | moderate | 6.29 | 6.23 | 5.98 | 6.24 | 4.76 | 5.65 | 4.95 | 6.31 | 98.2 | 2.12 | D420A|A475D|N460Y|A675D | 1.5mg/kg: 5755.23 | 27.20 | 1.26 | 0.52 | 1.55 | 0.52 | 0.87 | 3 | 100 | 20.7 | 3 | 95 | 100 | 93 | H1 | ||||||||||||
158 | IgG1 | 2a | 8.27e-11 | 5.9e-11 | 1.59e-09 | 6.82e-07 | 2.74e-10 | 32.5 | 86.9 | 150.0 | >25000 | >25000 | >25000 | 17.7 | 65.6 | 129.0 | 3 | 7 | >25000 | >25000 | 3.22e+02 | 5.96e+02 | 8.53e+02 | 30.0 | strong | strong | moderate | strong | weak | moderate | strong | 6.33 | 6.23 | 6.04 | 6.31 | 4.49 | 5.79 | 5.09 | 6.38 | 99.5 | 2.66 | 0.5mg/kg: 1957.06|1.5mg/kg: 6576.10 | 29.60 | 1.37 | 0.48 | 1.43 | 0.48 | 0.82 | 2 | 92 | 17.7 | 2 | 78 | 91 | 79 | H2 | |||||||||||||
159 | IgG1 | 2a | 1.66e-10 | 2.23e-10 | 2.49e-08 | 78.1 | 223.0 | 399.0 | >25000 | >25000 | >25000 | 30.5 | 89.5 | 170.0 | 11 | 39 | >25000 | >25000 | 6.07e+01 | 1.55e+02 | 2.68e+02 | 0.0 | strong | moderate | moderate | weak | weak | moderate | moderate | 6.3 | 6.21 | 6.03 | 6.3 | 4.64 | 5.8 | 5.05 | 6.38 | 100.0 | 2.12 | S591F|P491T | 1.5mg/kg: 7251.31 | 23.20 | 1.08 | 0.54 | 1.61 | 0.39 | 0.66 | 6 | 88 | 30.5 | 2 | 71 | 100 | 80 | H1 | ||||||||||||||
160 | IgG1 | 2a | 3.77e-10 | 7.23e-10 | 1.47e-08 | 2.66e-10 | 5.7e-08 | 62.3 | 183.0 | 335.0 | >25000 | >25000 | >25000 | 28.1 | 92.6 | 176.0 | 3 | 8 | 1609 | 3371 | 1.70e+00 | 2.66e+00 | 3.46e+00 | 20.0 | strong | strong | moderate | strong | moderate | moderate | strong | 6.29 | 6.18 | 6.01 | 6.2 | 5.0 | 5.7 | 5.05 | 6.38 | 99.6 | 2.41 | N487T|Y369H,N460Y|Y369H,Y489H | 1.5mg/kg: 6336.03 | 25.60 | 1.19 | 0.34 | 1.01 | 0.39 | 0.66 | 4 | 88 | 28.1 | 3 | 75 | 98 | 78 | H1 | ||||||||||||
161 | IgG1 | 2.33e-09 | 1.79e-09 | 6.03e-07 | 73.8 | 243.0 | 977.0 | >25000 | >25000 | >25000 | 1000.0 | 1020.0 | 1020.0 | 18 | 51 | >25000 | >25000 | 2.24e+02 | 5.73e+02 | 9.91e+02 | 100.0 | strong | weak | moderate | moderate | weak | weak | weak | 6.01 | 5.79 | 5.51 | 5.49 | 3.83 | 3.97 | 4.75 | 5.99 | 2.7 | 0.5mg/kg: 50.30|5mg/kg: 150.33 | 28.25 | 1.31 | 0.41 | 1.22 | 0.35 | 0.59 | 6 | 93 | 1000 | 78 | 67 | 93 | 78 | E3 | |||||||||||||||||
162 | IgG1 | 6b | 1.59e-09 | 1.68e-09 | 1.91e-07 | 2.19e-10 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 7435 | 16198 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | weak | moderate | moderate | weak | weak | weak | 6.22 | 6.13 | 5.85 | 6.18 | 3.84 | 3.96 | 4.91 | 6.27 | 96.8 | 2.99 | 29.40 | 1.36 | 0.66 | 1.97 | 0.57 | 0.97 | 79 | 89 | 25000 | 68 | 75 | 95 | 80 | A | ||||||||||||||||||
163 | IgG1 | 2a | 7.57e-10 | 3.31e-10 | 1.62e-07 | 8.4e-09 | 1.53e-07 | 613.0 | 2450.0 | 5100.0 | >25000 | >25000 | >25000 | 93.5 | 545.0 | 1130.0 | 66 | 400 | >25000 | >25000 | 4.26e+03 | 3.93e+04 | 1.44e+05 | 10.0 | strong | weak | moderate | moderate | weak | moderate | moderate | 6.23 | 6.17 | 5.92 | 6.2 | 4.54 | 5.74 | 4.96 | 6.31 | 100.0 | 2.28 | 1.5mg/kg: 2476.54 | 25.05 | 1.16 | 0.52 | 1.54 | 0.40 | 0.68 | 44 | 92 | 93.5 | 12 | 81 | 92 | 81 | H1 | |||||||||||||
164 | IgG1 | 2a | 1.72e-10 | 9.78e-11 | 2.25e-09 | 1.05e-06 | 2.54e-08 | 45.1 | 132.0 | 240.0 | >25000 | >25000 | >25000 | 20.7 | 92.0 | 190.0 | 10 | 32 | >25000 | >25000 | 3.23e+02 | 6.06e+02 | 8.74e+02 | 30.0 | strong | moderate | moderate | strong | weak | strong | moderate | 6.23 | 6.22 | 6.0 | 6.26 | 5.15 | 5.73 | 5.03 | 6.34 | 97.0 | 2.64 | 1.5mg/kg: 4832.12 | 28.85 | 1.34 | 0.45 | 1.34 | 0.60 | 1.02 | 2 | 93 | 20.7 | 2 | 83 | 94 | 82 | H1 | |||||||||||||
165 | IgG1 | 1.01e-08 | 4.79e-09 | 7.61e-08 | 1.09e-08 | 11100.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 7520 | 17286 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 0.0 | moderate | weak | moderate | weak | weak | weak | weak | 3.87 | 3.68 | 3.71 | 3.58 | 3.82 | 3.96 | 4.69 | 4.49 | 2.1 | 5mg/kg: 50.91 | 26.40 | 1.23 | 0.56 | 1.67 | 0.24 | 0.41 | 85 | 94 | 25000 | 72 | 76 | 95 | 71 | E3 | ||||||||||||||||||
166 | IgG1 | 5b | 1.76e-10 | 1.12e-10 | 8.26e-10 | 4.75e-07 | 8.99e-11 | 1.32e-09 | 721.0 | 3990.0 | 9140.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 223 | 3222 | 5894 | 14375 | 1.68e+04 | 3.71e+04 | 5.90e+04 | moderate | moderate | moderate | moderate | weak | moderate | weak | 6.31 | 6.22 | 5.98 | 6.27 | 3.83 | 4.02 | 4.93 | 6.33 | 32.2 | 2.79 | 25.60 | 1.19 | 0.36 | 1.09 | 0.55 | 0.93 | 85 | 89 | 25000 | 74 | 78 | 81 | 69 | E4 | ||||||||||||||
167 | IgG1 | 2a | 1.68e-10 | 9.84e-11 | 1.87e-09 | 6.62e-07 | 3.82e-10 | 4.1e-08 | 47.0 | 129.0 | 225.0 | 1370.0 | 3640.0 | 4580.0 | 35.5 | 105.0 | 192.0 | 12 | 33 | >25000 | >25000 | 5.91e+02 | 6.88e+02 | 7.52e+02 | 20.0 | strong | strong | weak | strong | weak | strong | strong | 6.28 | 6.23 | 5.99 | 6.26 | 4.22 | 5.75 | 5.42 | 6.42 | 99.3 | 1.72 | A475V,S735L|N487T | 1.5mg/kg: 4909.76 | 25.05 | 1.16 | 0.61 | 1.82 | 0.88 | 1.48 | 3 | 90 | 35.5 | 2 | 83 | 82 | 67 | H4 | |||||||||||
168 | IgG1 | 2a | 1.31e-10 | 2.46e-10 | 2.41e-08 | 3.77e-10 | 57.0 | 211.0 | 392.0 | >25000 | >25000 | >25000 | 17.7 | 54.9 | 108.0 | 10 | 36 | 3695 | 11023 | 1.43e+03 | 2.01e+03 | 2.45e+03 | 30.0 | strong | strong | moderate | weak | moderate | weak | moderate | 6.29 | 6.17 | 6.0 | 6.23 | 4.73 | 5.73 | 4.97 | 6.17 | 100.0 | 1.78 | N460D | 0.5mg/kg: 934.70|1.5mg/kg: 5078.05 | 27.00 | 1.25 | 0.46 | 1.37 | 0.48 | 0.81 | 6 | 88 | 17.7 | 2 | 94 | 88 | 83 | H1 | |||||||||||||
169 | IgG1 | 2a | 2.57e-10 | 2.22e-10 | 3.38e-08 | 6.53e-10 | 90.8 | 304.0 | 588.0 | >25000 | >25000 | >25000 | 27.7 | 90.4 | 179.0 | 17 | 72 | 15670 | >25000 | 7.11e+02 | 1.53e+03 | 2.39e+03 | 0.0 | strong | strong | moderate | weak | moderate | weak | moderate | 6.31 | 6.18 | 5.99 | 6.24 | 5.1 | 5.73 | 4.98 | 6.24 | 100.0 | 2.87 | D839G | 1.5mg/kg: 4836.02 | 27.65 | 1.28 | 0.51 | 1.51 | 0.58 | 0.99 | 8 | 87 | 27.7 | 1 | 98 | 100 | 95 | H1 | |||||||||||||
170 | IgG1 | 5b | 3.59e-10 | 7.48e-10 | 1.16e-09 | 6.6e-07 | 2.55e-10 | 3.47e-09 | 1210.0 | 5480.0 | 11900.0 | >25000 | >25000 | >25000 | 871.0 | 1210.0 | 1310.0 | 1001 | 3347 | 1241 | 4183 | 2.34e+04 | 3.40e+04 | 4.23e+04 | moderate | moderate | strong | moderate | weak | weak | moderate | 6.26 | 6.16 | 5.93 | 6.24 | 3.87 | 4.02 | 5.1 | 6.3 | 17.4 | 2.24 | 25.45 | 1.18 | 0.42 | 1.25 | 0.23 | 0.40 | 77 | 87 | 871 | 79 | 79 | 87 | 96 | E4 | ||||||||||||||
171 | IgG1 | 1.15e-10 | 9.29e-11 | 5.25e-11 | 6.59e-10 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 10399 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | None | moderate | moderate | moderate | strong | weak | moderate | moderate | 6.24 | 6.14 | 5.93 | 6.24 | 3.83 | 4.02 | 5.12 | 6.31 | 4.5 | 2.42 | 26.15 | 1.21 | 0.64 | 1.91 | 0.42 | 0.71 | 84 | 91 | 25000 | 90 | 100 | 95 | 84 | E3 | ||||||||||||||||||
172 | IgG1 | 5b | 1.29e-10 | 3.11e-10 | 9.47e-09 | 2.57e-06 | 2.3e-10 | 7.44e-09 | 3110.0 | 18400.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2541 | 16021 | 4507 | 18697 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | weak | strong | weak | weak | weak | weak | 6.27 | 6.17 | 6.01 | 6.27 | 3.81 | 3.95 | 4.96 | 6.29 | 33.9 | 2.06 | 27.15 | 1.26 | 0.51 | 1.52 | 0.52 | 0.87 | 81 | 95 | 25000 | 51 | 83 | 92 | 76 | E4 | ||||||||||||||
173 | IgG1 | 1.74e-09 | 7.61e-10 | 8.45e-08 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2 | 19 | >25000 | >25000 | 1.13e+02 | 2.86e+02 | 4.92e+02 | 40.0 | strong | weak | moderate | moderate | weak | weak | moderate | 6.2 | 6.06 | 5.85 | 6.08 | 3.86 | 5.1 | 5.02 | 6.2 | 2.26 | 0.5mg/kg: 445.09|5mg/kg: 2113.11 | 24.75 | 1.15 | 0.55 | 1.64 | 0.42 | 0.72 | 33 | 95 | 25000 | 79 | 92 | 94 | 80 | E2 | ||||||||||||||||||||
174 | IgG | >25000 | >25000 | >25000 | 1680.0 | 1700.0 | 1710.0 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | weak | weak | moderate | moderate | weak | weak | weak | 3.84 | 3.68 | 3.69 | 3.59 | 3.84 | 3.95 | 4.71 | 4.35 | 8.3 | 1.59 | 22.95 | 1.06 | 0.42 | 1.25 | 0.50 | 0.85 | ||||||||||||||||||||||||||||||||||
175 | IgG | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | weak | weak | strong | moderate | weak | moderate | weak | 3.84 | 3.7 | 3.69 | 3.63 | 3.82 | 3.92 | 4.74 | 4.39 | 3.8 | 1.82 | 23.95 | 1.11 | 0.40 | 1.19 | 0.34 | 0.57 | ||||||||||||||||||||||||||||||||||
176 | IgG | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | weak | weak | moderate | moderate | weak | weak | weak | 3.85 | 3.69 | 3.7 | 3.57 | 3.81 | 3.95 | 4.62 | 4.3 | 6.7 | 1.7 | 23.60 | 1.10 | 0.41 | 1.21 | 0.47 | 0.80 | |||||||||||||||||||||||||||||||||||||
177 | IgG | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | weak | weak | moderate | moderate | weak | moderate | weak | 3.86 | 3.7 | 3.71 | 3.57 | 3.84 | 3.93 | 4.7 | 4.4 | 11.2 | 1.77 | 24.55 | 1.14 | 0.66 | 1.97 | 0.58 | 0.99 | ||||||||||||||||||||||||||||||||||
178 | IgG | 5b | 6.98e-10 | 5.1e-10 | 1.49e-07 | 3.2e-10 | 6.83e-09 | 21000.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | weak | moderate | moderate | weak | weak | weak | 6.26 | 6.14 | 5.91 | 6.15 | 3.83 | 3.93 | 4.82 | 6.2 | 46.1 | 1.76 | 26.75 | 1.24 | 0.71 | 2.13 | 0.49 | 0.83 | 86 | 90 | 25000 | 90 | 90 | 95 | 72 | E3 | |||||||||||||||
179 | IgG | 2d | 4.7e-10 | 1.88e-10 | 2.24e-08 | 1.85e-09 | 4.38e-08 | 685.0 | 1950.0 | 3400.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 99 | 432 | 24497 | >25000 | 1.94e+02 | 4.67e+02 | 7.81e+02 | 10.0 | strong | moderate | moderate | moderate | weak | weak | weak | 6.27 | 6.08 | 6.0 | 6.19 | 4.29 | 5.4 | 5.06 | 6.21 | 100.0 | 3.34 | T470I | 1.5mg/kg: 6142.99 | 26.15 | 1.21 | 0.41 | 1.24 | 0.47 | 0.80 | 40 | 96 | 25000 | 90 | 90 | 79 | 90 | H3 | ||||||||||||
180 | IgG | 3b | 1.07e-09 | 5.92e-10 | 9.92e-07 | 1.19e-10 | 3.37e-08 | 772.0 | 5860.0 | 21800.0 | 5.32 | 28.0 | 239.0 | 3720.0 | >25000 | >25000 | 19 | 134 | <0.32 | 1 | 2.38e+03 | 2.45e+04 | 9.60e+04 | 0.0 | moderate | moderate | weak | weak | weak | weak | weak | 3.92 | 4.77 | 3.72 | 3.59 | 3.84 | 3.96 | 4.74 | 5.43 | 100.0 | 2.53 | P1181L | 0.5mg/kg: 50.30|1.5mg/kg: 57.77 | 25.40 | 1.18 | 0.38 | 1.12 | 0.39 | 0.65 | 65 | 37 | 3720 | 39 | 100 | 88 | 95 | B | ||||||||||||
181 | IgG1 | 5c | 8.23e-11 | 3.23e-11 | 2.09e-09 | 1.5e-06 | 2.72e-11 | 12.3 | 26.6 | 42.7 | 1.95 | 6.5 | 12.1 | 3.08 | 9.24 | 17.8 | 1 | 5 | 1 | 4 | 4.98e+01 | 8.74e+01 | 1.21e+02 | 100.0 | strong | strong | moderate | moderate | moderate | moderate | moderate | 6.36 | 6.32 | 5.99 | 6.35 | 6.23 | 5.87 | 6.62 | 6.39 | 72.4 | 3.76 | 0.5mg/kg: 2041.25|1.5mg/kg: 10722.74 | 1 | 3 | 3.08 | 2 | 96 | 100 | 100 | H1 | |||||||||||||||||||
182 | IgG1 | 2d | 9.44e-11 | 1.05e-10 | 1.9e-08 | 12.2 | 31.0 | 52.2 | >25000 | >25000 | >25000 | 3.9 | 15.2 | 27.4 | 2 | 6 | >25000 | >25000 | 5.88e+01 | 9.97e+01 | 1.36e+02 | None | strong | strong | moderate | strong | weak | moderate | moderate | 6.25 | 6.21 | 5.96 | 6.26 | 6.16 | 5.88 | 5.7 | 6.32 | 100.0 | 3.11 | 0.5mg/kg: 2631.19 | 0 | 88 | 3.9 | 0 | 82 | 100 | 100 | H3 | |||||||||||||||||||||
183 | IgG | 2d | 3.23e-11 | 1.71e-11 | 6.97e-09 | 1.66e-09 | 2.03e-11 | 3.58e-10 | 50.2 | 137.0 | 229.0 | 21.3 | 72.0 | 141.0 | >25000 | >25000 | >25000 | 12 | 35 | <0.32 | 4 | 2.46e+01 | 4.92e+01 | 7.37e+01 | 70.0 | strong | strong | moderate | strong | strong | strong | strong | 6.38 | 6.35 | 6.05 | 6.33 | 6.01 | 5.78 | 6.64 | 6.42 | 100.0 | 2.78 | 1.5mg/kg: 9202.66 | 0 | 3 | 25000 | 91 | 61 | 60 | 91 | B | ||||||||||||||||||
184 | IgG | 4.43e-11 | 2.02e-11 | 3.44e-08 | 1.29e-11 | 1.23e-09 | 43.9 | 197.0 | 540.0 | 9.44 | 32.8 | 68.7 | 13.5 | 97.6 | 439.0 | 4 | 16 | 0.38 | 1 | 3.74e+01 | 2.42e+02 | 7.19e+02 | 70.0 | strong | moderate | moderate | moderate | weak | moderate | strong | 6.32 | 6.25 | 5.9 | 6.31 | 5.89 | 5.71 | 5.21 | 6.34 | 100.0 | 3.26 | 0.5mg/kg: 1627.71|1.5mg/kg: 4718.71 | 28.40 | 1.32 | 0.21 | 0.64 | 7 | 8 | 13.5 | 8 | 78 | 86 | 9 | G | ||||||||||||||||
185 | IgG | 2d | 1.24e-11 | 1.12e-11 | 1.23e-08 | 4.41 | 12.2 | 23.0 | >25000 | >25000 | >25000 | 11.5 | 50.6 | 159.0 | 1 | 4 | >25000 | >25000 | 5.29e+00 | 1.00e+01 | 1.46e+01 | 70.0 | moderate | weak | moderate | moderate | weak | weak | weak | 6.26 | 6.29 | 5.89 | 5.27 | 6.2 | 5.34 | 4.75 | 6.03 | 100.0 | 2.75 | 1.5mg/kg: 12698.69 | 23.75 | 1.28 | 0.63 | 2.17 | 0.14 | 0.32 | 1 | 100 | 11.5 | 11 | 100 | 100 | 98 | H3 | |||||||||||||||
186 | IgG | 1 | 3.43e-10 | 1.26e-10 | 6.1e-09 | 117.0 | 374.0 | 671.0 | >25000 | >25000 | >25000 | 128.0 | 406.0 | 684.0 | 44 | 138 | >25000 | >25000 | 6.35e+01 | 1.49e+02 | 2.44e+02 | 20.0 | strong | moderate | moderate | moderate | weak | moderate | strong | 6.28 | 6.22 | 5.81 | 6.27 | 5.49 | 5.61 | 5.12 | 6.3 | 99.0 | 2.42 | 1.5mg/kg: 4044.10 | 26.40 | 1.43 | 0.20 | 0.69 | 0.20 | 0.44 | 12 | 92 | 128 | 9 | 100 | 100 | 96 | H1 | |||||||||||||||
187 | IgG | 1.83e-10 | 6.74e-11 | 5.4e-09 | 2.51e-08 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2 | 25 | >25000 | >25000 | 6.92e+01 | 2.39e+02 | 4.93e+02 | None | strong | weak | moderate | weak | weak | moderate | moderate | 6.12 | 6.04 | 5.69 | 5.95 | 5.72 | 5.31 | 4.9 | 6.09 | 19.8 | 2.0 | 0.5mg/kg: 72.62 | 21.85 | 1.18 | 0.11 | 0.38 | 0.17 | 0.39 | 39 | 96 | 25000 | 60 | 98 | 100 | 95 | E2 | ||||||||||||||||||
188 | IgG | 1.39e-08 | 8.44e-09 | 7.16e-07 | 2.01e-09 | 404.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 15 | 242 | >12500 | >12500 | 3.40e+02 | 1.37e+03 | 3.08e+03 | weak | weak | moderate | weak | weak | weak | weak | 3.84 | 3.69 | 3.66 | 3.59 | 3.81 | 3.93 | 4.81 | 4.35 | 19.4 | 1.65 | 27.90 | 1.51 | 0.21 | 0.72 | 0.16 | 0.36 | 39 | 98 | 25000 | 95 | 95 | 100 | 100 | E3 | |||||||||||||||||
189 | IgG | 2.87e-09 | 1.01e-09 | 3.14e-07 | 108.0 | >25000 | >25000 | 1230.0 | 1260.0 | 1260.0 | 2100.0 | 3220.0 | 3570.0 | 22 | 142 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | strong | weak | moderate | weak | weak | moderate | weak | 5.94 | 5.68 | 5.3 | 5.26 | 5.9 | 4.53 | 4.75 | 5.5 | 3.0 | 2.42 | del140|del141-144 | 23.00 | 1.24 | 0.07 | 0.24 | 0.21 | 0.47 | 35 | 98 | 2100 | 96 | 86 | 99 | 82 | E3 | |||||||||||||||||
190 | IgG | 3.63e-09 | 1.55e-09 | 4.07e-07 | 158.0 | >25000 | >25000 | 578.0 | 2370.0 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | weak | moderate | moderate | weak | weak | moderate | weak | 5.56 | 5.26 | 4.86 | 3.94 | 5.52 | 3.96 | 4.78 | 5.18 | 3.8 | 1.62 | 23.00 | 1.24 | 0.27 | 0.91 | 0.30 | 0.68 | 34 | 100 | 25000 | 100 | 94 | 88 | 87 | E3 | ||||||||||||||||||||||
191 | IgG | 1.42e-09 | 7.91e-10 | 1.18e-07 | 96.7 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 18 | 82 | >25000 | >25000 | 2.48e+01 | 5.06e+01 | 7.68e+01 | None | moderate | weak | moderate | weak | weak | weak | weak | 5.69 | 5.47 | 5.03 | 4.24 | 3.85 | 3.98 | 4.72 | 5.41 | 1.4 | 1.83 | del141-144 | 0.5mg/kg: 50.30 | 22.45 | 1.21 | 0.08 | 0.28 | 0.08 | 0.18 | 21 | 97 | 25000 | 100 | 99 | 92 | 84 | E3 | |||||||||||||||
192 | IgG | 3.29e-11 | 3.75e-11 | 9.02e-09 | 5.67e-09 | 2.37e-11 | 53.9 | 86.1 | 113.0 | 488.0 | 1700.0 | 2320.0 | 575.0 | 1750.0 | 2350.0 | 0.43 | 3 | 7 | 30 | 9.22e+00 | 2.53e+01 | 4.56e+01 | 50.0 | strong | moderate | moderate | weak | weak | moderate | moderate | 6.29 | 6.28 | 5.96 | 6.28 | 6.08 | 5.59 | 6.08 | 6.31 | 100.0 | 2.22 | 1.5mg/kg: 5711.47 | 22.90 | 1.24 | 0.12 | 0.41 | 0.28 | 0.61 | ||||||||||||||||||||||
193 | IgG | 7.03e-11 | 1.94e-11 | 1.06e-08 | 4.54e-07 | 4.53e-11 | 68.3 | 117.0 | 163.0 | 478.0 | 1110.0 | 1360.0 | 410.0 | 1970.0 | 3530.0 | 4 | 11 | 70 | 229 | 1.24e+01 | 3.26e+01 | 5.73e+01 | 40.0 | strong | strong | moderate | weak | moderate | moderate | moderate | 6.26 | 6.19 | 5.99 | 6.21 | 6.09 | 5.7 | 5.38 | 6.25 | 100.0 | 1.67 | del140-142,V143F | 1.5mg/kg: 4552.18 | 24.10 | 1.30 | 0.12 | 0.41 | 0.15 | 0.34 | |||||||||||||||||||||
194 | IgG | 8.36e-11 | 4.91e-11 | 3.73e-08 | 7.01e-07 | 4.99e-11 | 8.46e-09 | 47.2 | 83.4 | 117.0 | 229.0 | 533.0 | 926.0 | 145.0 | 492.0 | 803.0 | 2 | 17 | 7 | 96 | 1.56e+01 | 3.87e+01 | 6.58e+01 | 30.0 | strong | moderate | moderate | moderate | weak | moderate | moderate | 6.17 | 6.1 | 5.87 | 6.07 | 6.08 | 5.55 | 5.22 | 6.07 | 100.0 | 2.18 | del140-142,V143F | 0.5mg/kg: 249.25|1.5mg/kg: 640.17 | 13.30 | 0.72 | 0.14 | 0.48 | 0.12 | 0.28 | ||||||||||||||||||||
195 | IgG | 2.61e-11 | 2.8e-11 | 8.64e-09 | 8.85e-07 | 1.32e-11 | 65.2 | 108.0 | 146.0 | 590.0 | 1710.0 | 3420.0 | >25000 | >25000 | >25000 | 2 | 21 | 632 | 2120 | 9.80e+00 | 2.38e+01 | 3.99e+01 | 30.0 | moderate | strong | moderate | strong | moderate | moderate | moderate | 6.26 | 6.19 | 5.99 | 6.2 | 6.12 | 5.75 | 5.69 | 6.34 | 100.0 | 1.92 | 0.5mg/kg: 3777.52 | 22.65 | 1.22 | 0.07 | 0.23 | 0.09 | 0.20 | ||||||||||||||||||||||
196 | IgG | 2.98e-10 | 1.61e-10 | 5.51e-07 | 7.83e-11 | 2.72e-08 | 85.1 | 162.0 | 237.0 | 296.0 | 1190.0 | 1960.0 | >25000 | >25000 | >25000 | 14 | 67 | 100 | 290 | 3.16e+01 | 7.27e+01 | 1.18e+02 | 0.0 | strong | strong | moderate | weak | weak | weak | weak | 6.15 | 6.05 | 5.78 | 6.02 | 6.05 | 5.32 | 5.19 | 6.02 | 79.7 | 2.67 | 1.5mg/kg: 891.49 | 23.40 | 1.26 | 0.14 | 0.50 | 0.07 | 0.17 | ||||||||||||||||||||||
197 | IgG | 7.71e-11 | 3.51e-11 | 3.33e-08 | 7.33e-07 | 2.03e-11 | 8.38e-09 | 29.0 | 66.1 | 104.0 | 286.0 | 973.0 | 1990.0 | >25000 | >25000 | >25000 | 3 | 21 | 225 | 690 | 8.49e+00 | 3.25e+01 | 7.14e+01 | None | strong | moderate | moderate | strong | weak | strong | strong | 6.22 | 6.15 | 5.81 | 6.14 | 6.1 | 5.52 | 5.15 | 6.09 | 93.0 | 2.75 | 0.5mg/kg: 379.56 | 24.75 | 1.34 | 0.25 | 0.85 | 0.18 | 0.41 | |||||||||||||||||||||
198 | IgG | 4.14e-11 | 2.69e-11 | 3.33e-08 | 1.17e-06 | 1.64e-11 | 4.34e-09 | 61.0 | 130.0 | 198.0 | 74.0 | 211.0 | 396.0 | 320.0 | 917.0 | 1570.0 | 7 | 39 | 24 | 86 | 6.18e+00 | 2.79e+01 | 6.73e+01 | 30.0 | strong | moderate | moderate | strong | weak | moderate | moderate | 6.21 | 6.14 | 5.89 | 6.12 | 6.09 | 5.25 | 4.94 | 6.13 | 100.0 | 2.41 | 0.5mg/kg: 333.11|1.5mg/kg: 1564.84 | 24.20 | 1.31 | 0.03 | 0.10 | 0.14 | 0.31 | |||||||||||||||||||||
199 | IgG | 1 | 2.3e-10 | 1.42e-10 | 8.33e-09 | 3.59e-07 | 3.29e-10 | 73.4 | 165.0 | 257.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 29 | 122 | >25000 | >25000 | 2.53e+01 | 7.36e+01 | 1.37e+02 | None | strong | strong | moderate | weak | weak | moderate | moderate | 6.22 | 6.17 | 5.86 | 6.14 | 6.1 | 5.58 | 5.16 | 6.22 | 99.0 | 3.54 | 0.5mg/kg: 288.99 | 26.25 | 1.42 | 0.13 | 0.45 | 0.26 | 0.58 | 1 | 100 | 25000 | 76 | 100 | 100 | 100 | H1 | |||||||||||||
200 | IgG | 2a | 5.6e-11 | 7.51e-11 | 4.61e-08 | 9.41e-09 | 60.6 | 182.0 | 340.0 | >25000 | >25000 | >25000 | 11.6 | 50.9 | 111.0 | 13 | 61 | >25000 | >25000 | 2.71e+01 | 9.19e+01 | 1.88e+02 | moderate | moderate | weak | weak | weak | moderate | weak | 6.17 | 6.07 | 5.72 | 5.18 | 4.53 | 3.75 | 4.86 | 5.43 | 100.0 | 0.375 | 23.00 | 1.24 | 0.12 | 0.43 | 0.17 | 0.38 | 25 | 100 | 11.6 | 11 | 99 | 100 | 100 | H1 | ||||||||||||||||
201 | IgG | 2d | 3.51e-11 | 1.78e-11 | 2.35e-09 | 7.13e-07 | 9.49 | 25.4 | 44.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | <0.32 | <0.32 | >25000 | >25000 | 2.63e+01 | 4.59e+01 | 6.35e+01 | strong | moderate | strong | strong | weak | moderate | moderate | 6.03 | 5.99 | 5.7 | 5.98 | 5.8 | 5.63 | 5.21 | 6.23 | 99.4 | 4.58 | F490L|F486I | 24.40 | 1.32 | 0.04 | 0.16 | 0.13 | 0.29 | 8 | 100 | 25000 | 100 | 100 | 100 | 100 | H3 | |||||||||||||||
202 | IgG1 | 2a | 4.48e-10 | 2.34e-10 | 1.26e-10 | 4.34e-08 | 741.0 | 2260.0 | 4380.0 | >25000 | >25000 | >25000 | 330.0 | >25000 | >25000 | 477 | 2096 | 6.05e+03 | 1.47e+04 | 2.50e+04 | 0.0 | strong | weak | weak | weak | weak | strong | strong | 6.28 | 6.12 | 5.98 | 6.19 | 5.84 | 5.06 | 4.93 | 6.25 | 100.0 | 2.24 | 1.5mg/kg: 5992.57 | 25.65 | 1.39 | 0.13 | 0.45 | 0.17 | 0.39 | 46 | 72 | 330 | 25 | 96 | 100 | 100 | H1 | ||||||||||||||||
203 | IgG1 | 2d | 2.4e-11 | 1.43e-11 | 3.72e-10 | 1.21e-07 | 3.03e-08 | 3.32e-08 | 14.4 | 46.5 | 86.3 | >25000 | >25000 | >25000 | 11.3 | 31.6 | 57.1 | 9 | 24 | >25000 | >25000 | 6.73e+00 | 1.45e+01 | 2.27e+01 | strong | moderate | strong | moderate | weak | moderate | moderate | 6.07 | 6.02 | 5.72 | 6.0 | 6.39 | 4.86 | 4.88 | 6.2 | 99.2 | 0.952 | 21.35 | 1.15 | 0.12 | 0.40 | 0.24 | 0.53 | 100 | 100 | 11.3 | 99 | 100 | 100 | 100 | H3 | ||||||||||||||
204 | IgG1 | 2d | 8.75e-11 | 3.75e-11 | 2.67e-10 | 2.48e-07 | 8.16e-08 | 5.77e-08 | 31.0 | 79.4 | 131.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 4 | 10 | >25000 | >25000 | 6.07e+01 | 1.01e+02 | 1.36e+02 | 90.0 | strong | strong | strong | moderate | moderate | moderate | moderate | 6.03 | 5.97 | 5.66 | 5.96 | 6.45 | 5.22 | 5.01 | 6.2 | 97.8 | 2.06 | 1.5mg/kg: 13579.78 | 26.30 | 1.42 | 0.12 | 0.41 | 0.13 | 0.29 | 100 | 100 | 25000 | 100 | 100 | 100 | 100 | H3 | ||||||||||||
205 | IgG1 | 2d | 1.34e-10 | 3.68e-11 | 1.67e-09 | 4.75e-07 | 3.69e-08 | 17.3 | 50.1 | 89.2 | >25000 | >25000 | >25000 | 139.0 | 453.0 | 788.0 | 3 | 21 | >25000 | >25000 | 1.66e+01 | 4.64e+01 | 8.46e+01 | None | strong | moderate | strong | strong | moderate | moderate | moderate | 6.0 | 5.99 | 5.66 | 5.96 | 6.49 | 5.08 | 4.95 | 6.23 | 99.0 | 2.22 | 0.5mg/kg: 1508.09 | 24.90 | 1.35 | 0.10 | 0.34 | 0.14 | 0.30 | 0 | 100 | 139 | 26 | 94 | 100 | 100 | H3 | |||||||||||||
206 | IgG1 | 1.01e-10 | 8.16e-11 | 4.85e-08 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 1 | 4 | >25000 | >25000 | 2.18e+00 | 5.35e+00 | 9.04e+00 | 90.0 | moderate | weak | moderate | moderate | weak | moderate | moderate | 6.03 | 5.98 | 5.68 | 5.94 | 6.37 | 4.72 | 4.92 | 6.12 | 0.934 | 1.5mg/kg: 183.65 | 25.70 | 1.39 | 0.19 | 0.66 | 0.14 | 0.30 | 55 | 98 | 25000 | 81 | 100 | 93 | 100 | E2 | ||||||||||||||||||||
207 | IgG1 | 1.3e-09 | 5.66e-10 | 4.16e-07 | 1.45e-07 | 76.2 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 14 | 33 | >25000 | >25000 | 1.93e+01 | 5.26e+01 | 9.46e+01 | None | moderate | weak | moderate | weak | weak | moderate | moderate | 5.82 | 5.81 | 5.47 | 5.51 | 5.64 | 4.82 | 5.26 | 5.56 | 11.8 | 1.15 | 0.5mg/kg: 50.30 | 23.65 | 1.28 | 0.12 | 0.43 | 0.20 | 0.44 | 25 | 96 | 25000 | 100 | 93 | 100 | 100 | E3 | |||||||||||||||
208 | IgG1 | 2c | 5.22e-11 | 2.65e-11 | 5.08e-09 | 1.37e-06 | 2.47e-11 | 62.6 | 94.8 | 126.0 | 51.3 | 120.0 | 192.0 | 7.21 | 53.3 | 145.0 | 77 | 147 | >25000 | >25000 | 8.34e+01 | 2.01e+02 | 3.38e+02 | strong | weak | moderate | strong | weak | moderate | weak | 6.05 | 6.01 | 5.71 | 5.99 | 4.63 | 4.58 | 4.82 | 6.2 | 100.0 | 1.93 | 24.70 | 1.34 | 0.25 | 0.86 | 0.17 | 0.37 | 1 | 20 | 7.21 | 0 | 97 | 100 | 98 | H1 | |||||||||||||||
209 | IgG1 | 1.41e-07 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | weak | weak | weak | weak | weak | moderate | moderate | 3.29 | 3.1 | 2.99 | 2.77 | 3.68 | 4.76 | 5.31 | 4.34 | 32.7 | 0.632 | 23.60 | 1.28 | 0.06 | 0.20 | 0.18 | 0.41 | 100 | 100 | 92 | 88 | 92 | 100 | |||||||||||||||||||||||||||||||||
210 | IgG | 3.21e-09 | 1.37e-09 | 2.86e-07 | 156.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 209 | 2382 | 3.82e+01 | 1.30e+02 | 2.65e+02 | 80.0 | moderate | weak | moderate | weak | weak | weak | weak | 5.65 | 5.63 | 5.23 | 5.33 | 5.49 | 4.81 | 5.26 | 5.54 | 4.7 | 1.35 | 1.5mg/kg: 7717.11 | 25.35 | 1.37 | 0.09 | 0.29 | 0.25 | 0.56 | 1 | 1 | 25000 | 2 | 17 | 18 | 56 | E3 | ||||||||||||||||||
211 | IgG1 | 2d | 8.99e-12 | 7.69e-12 | 2.01e-10 | 1.02e-07 | 3.98e-08 | 5.16 | 10.5 | 15.9 | >25000 | >25000 | >25000 | 2.39 | 8.61 | 17.1 | 0.5 | 2 | 4.54e+00 | 5.64e+00 | 6.41e+00 | None | strong | strong | moderate | moderate | weak | moderate | weak | 6.16 | 6.05 | 5.76 | 5.98 | 6.42 | 4.23 | 4.97 | 6.15 | 99.6 | 1.26 | 0.5mg/kg: 2316.08 | 0 | 98 | 2.39 | 0 | 100 | 98 | 100 | H3 | |||||||||||||||||||||
212 | IgG1 | 3.67e-11 | 1.72e-11 | 6.3e-10 | 3.17e-07 | 2.04e-11 | 7.12e-08 | 71.0 | 152.0 | 241.0 | 29.2 | 109.0 | 215.0 | 61.3 | 243.0 | 461.0 | 30 | 100 | 17 | 49 | 7.44e+01 | 1.09e+02 | 1.36e+02 | 20.0 | moderate | strong | strong | moderate | weak | moderate | weak | 6.1 | 6.01 | 5.71 | 5.98 | 4.93 | 4.96 | 5.07 | 6.17 | 96.6 | 1.76 | N440D | 0.5mg/kg: 1225.84|1.5mg/kg: 3745.19 | 25.45 | 1.38 | 0.08 | 0.27 | 0.21 | 0.47 | 1 | 0 | 61.3 | 0 | 90 | 97 | 99 | |||||||||||||
213 | IgG1 | 3b | 3.64e-11 | 1.72e-11 | 6.74e-11 | 8.74e-08 | 2.74e-11 | 1.08e-09 | 28.4 | 89.8 | 160.0 | 33.6 | 102.0 | 189.0 | 64.8 | 122.0 | 189.0 | 11 | 32 | 21 | 61 | 7.97e+01 | 1.25e+02 | 1.62e+02 | 20.0 | strong | moderate | strong | strong | weak | moderate | moderate | 6.09 | 6.01 | 5.71 | 5.95 | 4.82 | 5.2 | 5.22 | 6.05 | 98.0 | 2.88 | G504D | 0.5mg/kg: 1644.34|1.5mg/kg: 6022.87 | 25.60 | 1.38 | 0.09 | 0.29 | 0.11 | 0.24 | 5 | 6 | 64.8 | 5 | 97 | 100 | 100 | A | |||||||||||
214 | IgG1 | 6b | 1.24e-10 | 4.4e-11 | 7.1e-11 | 2.94e-06 | 3.93e-11 | 338.0 | 945.0 | 1220.0 | 153.0 | 400.0 | 688.0 | 849.0 | 1310.0 | 1570.0 | 158 | 512 | 147 | 435 | 8.56e+02 | 1.85e+03 | 2.91e+03 | 0.0 | moderate | moderate | strong | strong | weak | moderate | moderate | 6.09 | 5.99 | 5.72 | 5.95 | 4.7 | 4.94 | 5.12 | 6.06 | 95.5 | 1.99 | 1.5mg/kg: 6771.51 | 25.25 | 1.36 | 0.06 | 0.19 | 0.42 | 0.94 | 8 | 9 | 849 | 8 | 100 | 100 | 100 | A | |||||||||||||
215 | IgG1 | 4a | 3.24e-11 | 1.12e-11 | 9.05e-10 | 6.19e-07 | 20.7 | 61.5 | 111.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 1 | 6 | >25000 | >25000 | 3.89e+01 | 9.42e+01 | 1.58e+02 | 60.0 | strong | weak | strong | strong | weak | moderate | moderate | 6.07 | 6.0 | 5.71 | 5.97 | 5.09 | 4.72 | 4.86 | 6.2 | 96.1 | 2.46 | 0.5mg/kg: 6187.27 | 25.45 | 1.38 | 0.14 | 0.47 | 0.12 | 0.28 | 1 | 100 | 25000 | 98 | 100 | 100 | 100 | H1 | ||||||||||||||
216 | IgG1 | 5.4e-09 | 2.59e-09 | 3.85e-09 | 3560.0 | 8730.0 | 14300.0 | >25000 | >25000 | >25000 | 615.0 | >25000 | >25000 | 671 | 2075 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 0.0 | moderate | strong | moderate | strong | moderate | moderate | moderate | 5.84 | 5.77 | 5.5 | 5.71 | 4.0 | 4.84 | 5.19 | 5.68 | 23.7 | 1.7 | 1.5mg/kg: 120.58 | 27.25 | 1.47 | 0.17 | 0.59 | 0.16 | 0.36 | ||||||||||||||||||||||||||
217 | IgG1 | 5.17e-10 | 6.33e-10 | 4.46e-10 | 636.0 | 1350.0 | 1990.0 | 702.0 | 1580.0 | 2370.0 | >25000 | >25000 | >25000 | 35 | 520 | 864 | 2489 | 3.84e+03 | 5.97e+03 | 7.74e+03 | 0.0 | strong | moderate | strong | strong | strong | strong | strong | 5.96 | 5.91 | 5.62 | 5.88 | 4.59 | 5.03 | 5.06 | 5.93 | 77.6 | 0.821 | 1.5mg/kg: 699.36 | 27.45 | 1.48 | 0.14 | 0.50 | 0.21 | 0.48 | ||||||||||||||||||||||||
218 | IgG1 | 2.64e-10 | 4.84e-11 | 6.07e-10 | 300.0 | 603.0 | 796.0 | 120.0 | 470.0 | 869.0 | 20.8 | 84.1 | 184.0 | 58 | 193 | 437 | 744 | 4.54e+03 | 6.52e+03 | 8.06e+03 | None | strong | strong | strong | strong | moderate | strong | strong | 6.05 | 6.0 | 5.7 | 6.09 | 5.38 | 5.11 | 4.85 | 6.17 | 96.5 | 3.86 | 0.5mg/kg: 387.92 | 47.25 | 1.68 | 5.00 | 21.28 | 2.23 | 1.59 | ||||||||||||||||||||||||
219 | IgG1 | >25000 | >25000 | >25000 | 19.1 | 91.5 | 185.0 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | weak | weak | weak | weak | weak | moderate | weak | 3.37 | 3.11 | 3.01 | 2.75 | 3.65 | 4.71 | 5.31 | 4.34 | 2.5 | 0.658 | 30.75 | 1.09 | 0.49 | 2.11 | 1.16 | 0.82 | ||||||||||||||||||||||||||||||||||
220 | IgG1 | 4.27e-10 | 1.84e-10 | 1.89e-11 | 1.47e-10 | 8.03e-10 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 71.2 | 292.0 | 587.0 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | weak | moderate | moderate | weak | moderate | moderate | 6.0 | 5.95 | 5.62 | 5.86 | 4.41 | 4.93 | 5.2 | 5.92 | 0.1 | 0.493 | 31.95 | 1.13 | 0.15 | 0.66 | 0.73 | 0.53 | 93 | 97 | 71.2 | 94 | 90 | 94 | 94 | |||||||||||||||||||
221 | IgG1 | 1.55e-09 | 9.17e-10 | 3.55e-08 | 1.27e-08 | 150.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 91 | 361 | >25000 | >25000 | 1.94e+02 | 7.80e+02 | 1.76e+03 | 60.0 | moderate | weak | moderate | moderate | weak | moderate | moderate | 5.85 | 5.87 | 5.5 | 5.63 | 3.9 | 4.79 | 5.21 | 5.64 | 1.1 | 0.416 | 1.5mg/kg: 100.06 | 34.75 | 1.23 | 0.23 | 1.00 | 0.82 | 0.59 | 97 | 100 | 25000 | 94 | 99 | 100 | 100 | E3 | |||||||||||||||
222 | IgG1 | 4.44e-11 | 5.09e-11 | 5.94e-10 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 91 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | weak | weak | weak | weak | weak | weak | 5.97 | 5.94 | 5.62 | 5.73 | 3.89 | 4.61 | 5.15 | 5.65 | 0.9 | 0.334 | 36.60 | 1.30 | 0.17 | 0.74 | 0.69 | 0.49 | 94 | 100 | 25000 | 100 | 97 | 100 | 99 | E3 | |||||||||||||||||||||
223 | IgG1 | 9.54e-11 | 4.71e-11 | 1.27e-09 | 3.28e-09 | 39.4 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 15 | 67 | >25000 | >25000 | 1.80e+02 | 3.54e+02 | 5.26e+02 | 10.0 | moderate | moderate | moderate | strong | weak | moderate | moderate | 6.1 | 6.0 | 5.71 | 5.95 | 4.79 | 4.48 | 4.93 | 6.12 | 8.6 | 1.03 | 1.5mg/kg: 362.34 | 36.55 | 1.30 | 0.29 | 1.26 | 1.05 | 0.75 | 23 | 94 | 25000 | 34 | 99 | 100 | 21 | E2 | |||||||||||||||
224 | IgG1 | 3.5e-10 | 2.16e-10 | 4.78e-10 | 2.31e-10 | 1.41e-09 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 1.01 | 0.989 | 0.981 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | moderate | moderate | strong | weak | moderate | moderate | 6.05 | 5.95 | 5.67 | 5.86 | 4.46 | 4.94 | 5.23 | 5.93 | 4.0 | 1.2 | 47.60 | 1.69 | 6.42 | 27.32 | 2.77 | 1.98 | 92 | 95 | 1.01 | 91 | 100 | 100 | 97 | |||||||||||||||||||
225 | IgG1 | 6.49e-10 | 4.69e-10 | 3.42e-10 | 5.86e-10 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | strong | moderate | strong | weak | moderate | moderate | 6.05 | 5.97 | 5.67 | 5.82 | 4.08 | 4.78 | 5.21 | 5.77 | 3.7 | 0.586 | 34.60 | 1.23 | 1.64 | 6.98 | 1.39 | 0.99 | 84 | 100 | 25000 | 100 | 100 | 100 | 100 | E3 | ||||||||||||||||||||||
226 | IgG1 | 7.87e-11 | 1.07e-10 | 1.27e-09 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 15652 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | moderate | weak | weak | weak | moderate | moderate | 6.01 | 5.96 | 5.67 | 5.82 | 4.04 | 4.68 | 5.15 | 5.83 | 1.8 | 0.647 | 33.45 | 1.19 | 0.12 | 0.51 | 0.14 | 0.10 | 78 | 100 | 25000 | 100 | 100 | 100 | 100 | E3 | |||||||||||||||||||||||
227 | IgG1 | 5.42e-10 | 2.68e-10 | 2.78e-10 | 4.05e-08 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | moderate | moderate | moderate | weak | moderate | weak | 6.03 | 5.97 | 5.68 | 5.92 | 4.53 | 4.65 | 5.04 | 5.99 | 4.8 | 0.912 | 29.50 | 1.05 | 0.34 | 1.43 | 0.11 | 0.08 | 91 | 99 | 25000 | 100 | 100 | 100 | 97 | E3 | ||||||||||||||||||||||
228 | IgG1 | 4.92e-10 | 2.92e-10 | 2.37e-10 | 5.02e-10 | 1110.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | strong | moderate | strong | weak | moderate | moderate | 6.01 | 5.96 | 5.65 | 5.81 | 4.08 | 4.71 | 5.2 | 5.77 | 0.9 | 0.339 | 22.86 | 0.81 | 0.31 | 1.32 | 0.32 | 0.23 | 100 | 100 | 25000 | 100 | 100 | 100 | 100 | E3 | ||||||||||||||||||||||
229 | IgG1 | 2.99e-10 | 2.18e-10 | 5.73e-10 | 1.57e-10 | 1.58e-09 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | moderate | weak | weak | weak | moderate | moderate | 5.98 | 5.94 | 5.66 | 5.91 | 4.53 | 4.56 | 4.94 | 6.01 | 0.7 | 1.9 | 41.40 | 1.47 | 0.12 | 0.49 | 0.82 | 0.59 | 100 | 100 | 25000 | 100 | 97 | 100 | 100 | E3 | |||||||||||||||||||||
230 | IgG1 | 5b | 3.72e-10 | 2.35e-10 | 5.29e-10 | 3.8e-07 | 2.42e-10 | 1.84e-09 | 2940.0 | 14300.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 5541 | 19055 | 3543 | 11203 | 1.42e+04 | 3.68e+04 | 6.43e+04 | moderate | weak | moderate | moderate | weak | moderate | weak | 5.99 | 5.96 | 5.65 | 5.88 | 4.16 | 4.66 | 5.1 | 5.9 | 18.8 | 0.487 | 39.45 | 1.40 | 0.26 | 1.11 | 0.94 | 0.67 | 78 | 92 | 25000 | 82 | 77 | 95 | 92 | |||||||||||||||
231 | IgG1 | 2b | 3.81e-11 | 8.55e-12 | 1.57e-10 | 5.37e-08 | 6.64e-12 | 1.26e-09 | 9.1 | 24.9 | 42.5 | 3.35 | 9.41 | 16.7 | 1020.0 | >25000 | >25000 | <0.32 | 0.71 | <0.32 | <0.32 | 7.39e+00 | 1.42e+01 | 2.09e+01 | 50.0 | strong | weak | strong | strong | moderate | moderate | strong | 5.97 | 6.0 | 5.66 | 5.88 | 4.77 | 4.4 | 4.82 | 6.15 | 99.1 | 3.43 | 1.5mg/kg: 8672.51 | 42.85 | 1.52 | 2.46 | 10.49 | 1.80 | 1.29 | 0 | 0 | 1020 | 22 | 70 | 72 | 70 | H2 | ||||||||||||
232 | IgG1 | 5c | 2.31e-10 | 1.67e-10 | 1.58e-09 | 4.12e-07 | 1.57e-10 | 4.92e-09 | 109.0 | 280.0 | 469.0 | 408.0 | 1060.0 | 1390.0 | 3240.0 | >25000 | >25000 | 148 | 523 | 498 | 2160 | 7.55e+02 | 1.89e+03 | 3.23e+03 | 10.0 | strong | moderate | strong | strong | moderate | moderate | moderate | 6.0 | 5.96 | 5.63 | 5.83 | 4.4 | 4.38 | 4.98 | 5.91 | 21.3 | 2.4 | 1.5mg/kg: 4886.74 | 41.75 | 1.48 | 0.37 | 1.57 | 0.71 | 0.51 | 14 | 32 | 3240 | 79 | 27 | 46 | 47 | G | ||||||||||||
233 | IgG1 | 1.6e-09 | 5.29e-10 | 2.13e-09 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | strong | weak | moderate | weak | weak | moderate | moderate | 5.84 | 5.82 | 5.51 | 5.76 | 4.13 | 4.66 | 5.08 | 5.84 | 0.8 | 2.33 | 36.25 | 1.29 | 0.39 | 1.64 | 0.79 | 0.56 | 89 | 99 | 25000 | 95 | 93 | 96 | 100 | ||||||||||||||||||||||||
234 | IgG1 | 1 | 1.54e-09 | 3.64e-10 | 2.32e-08 | 3.35e-10 | 222.0 | 658.0 | 1190.0 | 150.0 | 416.0 | 832.0 | 28.9 | 119.0 | 261.0 | 319 | 1442 | 1.18e+03 | 1.90e+03 | 2.51e+03 | strong | weak | moderate | weak | weak | moderate | moderate | 5.78 | 5.85 | 5.48 | 5.67 | 3.48 | 4.05 | 4.88 | 5.69 | 38.5 | 2.49 | 35.50 | 1.26 | 0.28 | 1.17 | 0.82 | 0.59 | 13 | 6 | 28.9 | 3 | 3 | 6 | 5 | H1 | ||||||||||||||||||
235 | IgG1 | 2.13e-11 | 1.13e-11 | 2.56e-10 | 1.19e-07 | 1.36e-11 | 2.76e-08 | 5.68 | 16.0 | 27.7 | 8.74 | 24.4 | 42.4 | 4.37 | 12.4 | 22.9 | 6 | 20 | 2 | 9 | 1.50e+01 | 2.33e+01 | 3.01e+01 | moderate | moderate | strong | strong | moderate | moderate | weak | 6.11 | 6.02 | 5.72 | 5.97 | 4.95 | 4.61 | 4.98 | 6.06 | 97.4 | 0.993 | 0.5mg/kg: 2514.91 | 35.35 | 1.26 | 2.35 | 10.00 | 3.11 | 2.22 | 0 | 0 | 4.37 | 0 | 100 | 90 | 86 | A | ||||||||||||||
236 | IgG1 | 1.74e-11 | 9.31e-12 | 4.43e-11 | 3.09e-08 | 7.9e-12 | 1.46e-09 | 9.59 | 28.9 | 51.3 | 8.73 | 23.3 | 40.2 | 10.0 | 29.1 | 53.3 | <0.32 | <0.32 | 1.68e+01 | 2.27e+01 | 2.70e+01 | 50.0 | strong | strong | strong | strong | strong | moderate | moderate | 6.15 | 6.07 | 5.74 | 6.02 | 5.3 | 4.55 | 4.78 | 6.02 | 99.2 | 1.83 | 1.5mg/kg: 7854.60 | 41.65 | 1.48 | 0.34 | 1.47 | 0.59 | 0.42 | 0 | 0 | 10 | 0 | 62 | 75 | 65 | H1 | |||||||||||||||
237 | IgG1 | 8.49e-11 | 4.34e-11 | 1.05e-10 | 3.2e-08 | 1.38e-10 | 5.45e-08 | 37.2 | 98.7 | 165.0 | 480.0 | 2290.0 | >25000 | 32.6 | 93.0 | 164.0 | 7 | 93 | 982 | 2985 | 1.80e+02 | 3.54e+02 | 5.26e+02 | 0.0 | moderate | strong | moderate | moderate | weak | moderate | moderate | 6.09 | 6.01 | 5.7 | 5.94 | 4.76 | 4.65 | 4.91 | 6.09 | 97.2 | 4.28 | 1.5mg/kg: 6489.24 | 42.15 | 1.50 | 2.98 | 12.66 | 1.90 | 1.36 | 100 | 99 | 32.6 | 83 | 87 | 100 | 100 | H2 | |||||||||||||
238 | IgG1 | 4c | 1.43e-10 | 1.33e-10 | 8.73e-10 | 3.87e-07 | 9.57e-11 | 9.24e-10 | 260.0 | 810.0 | 1450.0 | >25000 | >25000 | >25000 | 126.0 | 287.0 | 437.0 | 518 | 2418 | 3.54e+03 | 1.42e+04 | 3.20e+04 | 0.0 | 32.3 | 0.696 | 1.5mg/kg: 7996.73 | 38.60 | 1.37 | 0.10 | 0.43 | 0.72 | 0.51 | 57 | 93 | 126 | 90 | 35 | 100 | 85 | G | |||||||||||||||||||||||||||||
239 | IgG1 | 2a | 1.41e-10 | 3.65e-11 | 7.74e-09 | 3.85e-06 | 5.67e-11 | 3.08e-08 | 54.8 | 149.0 | 264.0 | 24.5 | 84.2 | 190.0 | 129.0 | 330.0 | 501.0 | 25 | 85 | 4 | 23 | 3.03e+02 | 5.64e+02 | 8.11e+02 | 0.0 | 98.3 | 0.997 | 0.5mg/kg: 1405.73|1.5mg/kg: 3947.68 | 36.90 | 1.31 | 0.28 | 1.21 | 1.33 | 0.95 | 3 | 10 | 129 | 4 | 100 | 100 | 100 | H2 | |||||||||||||||||||||||||||
240 | IgG | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 3885 | 12310 | moderate | moderate | weak | moderate | weak | weak | moderate | 4.07 | 3.88 | 3.78 | 5.2 | 3.08 | 4.41 | 5.02 | 5.52 | 11.5 | 0.858 | ||||||||||||||||||||||||||||||||||||||||
241 | IgG1 | 7a | 4.75e-11 | 4.72e-11 | 7.51e-10 | 6.59e-07 | 3.11e-11 | 1.76e-09 | 32.1 | 113.0 | 199.0 | 30.7 | 88.9 | 160.0 | 30.8 | 67.1 | 106.0 | 1 | 7 | 8 | 35 | 7.06e+01 | 1.05e+02 | 1.33e+02 | 70.0 | weak | weak | moderate | strong | weak | weak | weak | 3.92 | 3.68 | 3.76 | 3.42 | 4.16 | 4.58 | 5.03 | 3.91 | 100.0 | 1.45 | S371F | 1.5mg/kg: 9832.44 | 33.70 | 1.20 | 0.12 | 0.51 | 0.78 | 0.55 | 1 | 2 | 30.8 | 0 | 92 | 100 | 100 | C1 | |||||||||||
242 | IgG1 | 7a | 7.15e-11 | 6.52e-11 | 6.59e-10 | 4.91e-07 | 2.75e-11 | 5.12e-09 | 32.9 | 111.0 | 195.0 | 171.0 | 609.0 | 911.0 | 169.0 | 350.0 | 499.0 | 1 | 13 | 101 | 172 | 6.35e+01 | 1.16e+02 | 1.64e+02 | 80.0 | weak | weak | weak | moderate | weak | weak | weak | 3.94 | 3.68 | 3.8 | 3.4 | 4.24 | 4.58 | 5.0 | 3.98 | 100.0 | 1.13 | S371F,P384L|del374,P384L|del374-376,P384L | 0.5mg/kg: 7552.94 | 35.95 | 1.28 | 2.73 | 11.60 | 1.79 | 1.28 | 7 | 12 | 169 | 1 | 91 | 98 | 99 | C3 | |||||||||||
243 | IgG1 | 7a | 9.88e-11 | 9.08e-11 | 2.63e-09 | 1.61e-06 | 3.75e-11 | 1.73e-09 | 13.8 | 42.9 | 76.3 | 45.6 | 115.0 | 188.0 | 49.3 | 209.0 | 424.0 | 8 | 22 | 26 | 79 | 6.62e+01 | 9.27e+01 | 1.13e+02 | 100.0 | moderate | moderate | weak | weak | weak | weak | weak | 3.91 | 3.69 | 3.76 | 5.11 | 4.22 | 4.56 | 5.05 | 3.96 | 100.0 | 0.908 | S375F,N703S|N544S,N703S | 1.5mg/kg: 16820.39 | 18 | 32 | 49.3 | 5 | 87 | 98 | 100 | C3 | |||||||||||||||||
244 | IgG1 | 7a | 9.49e-11 | 8.81e-11 | 1.38e-09 | 1.14e-06 | 8.39e-11 | 8.57e-09 | 19.1 | 59.1 | 106.0 | 363.0 | 1090.0 | 1680.0 | 187.0 | 778.0 | >25000 | 234 | 566 | 6.95e+01 | 1.00e+02 | 1.24e+02 | 90.0 | weak | moderate | weak | moderate | weak | weak | weak | 3.93 | 4.23 | 3.79 | 3.42 | 5.09 | 4.72 | 5.02 | 5.24 | 92.9 | 1.03 | S375T|Y508H|S371F | 0.5mg/kg: 2695.93|1.5mg/kg: 13640.24 | 34.15 | 1.21 | 0.18 | 0.77 | 1.24 | 0.89 | 3 | 4 | 187 | 0 | 80 | 91 | 99 | C3 | |||||||||||||
245 | IgG1 | 3.21e-10 | 2.28e-10 | 1.06e-08 | 1.92e-10 | 31.8 | >25000 | >25000 | 3610.0 | >25000 | >25000 | >25000 | >25000 | >25000 | 1 | 8 | 12141 | >25000 | 2.27e+03 | 1.58e+04 | 4.93e+04 | 0.0 | moderate | moderate | weak | moderate | weak | weak | weak | 6.37 | 6.18 | 5.96 | 6.18 | 5.62 | 4.78 | 5.13 | 6.31 | 0.92 | 1.5mg/kg: 210.77 | 37.90 | 1.35 | 0.11 | 0.46 | 1.21 | 0.86 | 19 | 64 | 25000 | 48 | 95 | 95 | 61 | E2 | ||||||||||||||||
246 | IgG1 | 4.78e-10 | 5.22e-10 | 7.83e-09 | 7.49e-11 | 31.1 | 92.7 | 271.0 | 251.0 | >25000 | >25000 | >25000 | >25000 | >25000 | 19 | 39 | 12 | 33 | 1.28e+02 | 1.95e+02 | 2.50e+02 | 40.0 | strong | strong | moderate | strong | weak | weak | weak | 5.45 | 5.2 | 4.96 | 4.84 | 3.11 | 4.63 | 5.05 | 5.82 | 12.1 | 0.372 | del141-144 | 1.5mg/kg: 52.97 | 39.30 | 1.28 | 0.65 | 0.86 | 0.14 | 1.35 | 5 | 34 | 25000 | 93 | 100 | 98 | 100 | E2 | ||||||||||||||
247 | IgG1 | 1.03e-08 | 7.68e-09 | 3.22e-07 | 78.3 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 12 | 29 | >25000 | >25000 | 1.31e+02 | 3.24e+02 | 5.51e+02 | moderate | moderate | weak | moderate | weak | weak | weak | 5.71 | 5.59 | 5.25 | 5.32 | 3.18 | 4.73 | 5.0 | 6.0 | 5.8 | 0.882 | del141-144 | 38.15 | 1.24 | 4.83 | 6.35 | 0.47 | 4.65 | 32 | 100 | 25000 | 79 | 100 | 95 | 84 | E3 | |||||||||||||||||
248 | IgG1 | 1.74e-09 | 4.51e-09 | 1.06e-07 | 63 | 804 | >25000 | >25000 | 1.24e+03 | 2.32e+03 | 3.34e+03 | weak | moderate | weak | strong | weak | moderate | moderate | 5.32 | 5.4 | 5.13 | 5.22 | 4.3 | 4.64 | 5.09 | 5.07 | 24.7 | 0.816 | T67I | 39 | 98 | 92 | 96 | 100 | 88 | ||||||||||||||||||||||||||||||||||
249 | IgG1 | 2a | 7.19e-11 | 2.43e-11 | 9.81e-09 | 2.86e-08 | 48.9 | 123.0 | 236.0 | >25000 | >25000 | >25000 | 59.5 | 78.1 | 93.8 | 10 | 258 | >25000 | >25000 | 1.95e+03 | 3.08e+03 | 4.01e+03 | 40.0 | strong | moderate | moderate | strong | weak | weak | weak | 6.14 | 6.08 | 5.85 | 6.05 | 4.64 | 4.78 | 5.0 | 6.22 | 100.0 | 0.776 | N1023Y | 1.5mg/kg: 9652.42 | 31.50 | 1.02 | 1.10 | 1.45 | 0.07 | 0.65 | 2 | 100 | 59.5 | 0 | 98 | 100 | 89 | H4 | |||||||||||||
250 | IgG1 | 6a | 2.19e-10 | 1.13e-10 | 4.14e-10 | 3.21e-07 | 5.84e-11 | 5.7e-09 | 1090.0 | 3450.0 | 6370.0 | 1490.0 | 5280.0 | 7440.0 | >25000 | >25000 | >25000 | 131 | 2160 | 557 | 1664 | 1.69e+03 | 2.75e+03 | 3.65e+03 | 0.0 | moderate | moderate | moderate | strong | weak | moderate | moderate | 6.03 | 6.34 | 5.87 | 6.05 | 5.15 | 4.83 | 5.08 | 6.02 | 7.5 | 0.328 | 1.5mg/kg: 2650.09 | 32.40 | 1.05 | 2.33 | 3.06 | 0.26 | 2.60 | 85 | 100 | 25000 | 100 | 94 | 100 | 88 | A | ||||||||||||
251 | IgG1 | 5a | 1.64e-10 | 1.38e-10 | 1.71e-10 | 6.44e-08 | 6.18e-11 | 1.38e-09 | 104.0 | 250.0 | 412.0 | 17 | 391 | 34 | 102 | 3.40e+02 | 6.93e+02 | 1.05e+03 | 10.0 | strong | strong | moderate | moderate | weak | weak | weak | 6.3 | 6.25 | 5.89 | 6.17 | 4.91 | 4.9 | 5.16 | 6.27 | 3.9 | 1.43 | 0.5mg/kg: 1868.20|1.5mg/kg: 5311.08 | 6.20 | 0.20 | 0.93 | 1.22 | 0.07 | 0.70 | 13 | 11 | 9 | 22 | 92 | 81 | G | |||||||||||||||||||
252 | IgG1 | 2a | 4.06e-10 | 1.14e-10 | 1.51e-08 | 1.05e-08 | 1.67e-07 | 123.0 | 305.0 | 619.0 | >25000 | >25000 | >25000 | 45.2 | 127.0 | 239.0 | 64 | 150 | 476 | 856 | 2.89e+02 | 6.86e+02 | 1.14e+03 | 0.0 | strong | moderate | strong | moderate | weak | weak | moderate | 6.27 | 6.22 | 6.01 | 6.14 | 4.83 | 4.8 | 5.05 | 6.25 | 100.0 | 0.558 | 1.5mg/kg: 3961.93 | 35.30 | 1.15 | 1.44 | 1.89 | 0.07 | 0.75 | 10 | 100 | 45.2 | 4 | 98 | 100 | 100 | H4 | |||||||||||||
253 | IgG1 | 1.06e-09 | 8.58e-10 | 2.7e-08 | 22.6 | 77.1 | 171.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 1.72e+02 | 5.61e+02 | 1.12e+03 | moderate | weak | moderate | moderate | weak | weak | weak | 6.39 | 6.22 | 5.98 | 6.23 | 5.3 | 4.66 | 5.09 | 6.31 | 9.0 | 0.395 | del141 | 32.65 | 1.06 | 5.21 | 6.86 | 0.53 | 5.30 | 7 | 100 | 25000 | 100 | 100 | 100 | 100 | E3 | |||||||||||||||||||||
254 | IgG1 | 2.4e-11 | 1.3e-11 | 7.93e-09 | 3.79e-10 | 21.4 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | <0.32 | 3 | 22 | 71 | 1.71e+01 | 4.45e+01 | 7.79e+01 | 80.0 | strong | moderate | moderate | moderate | weak | moderate | moderate | 6.46 | 6.14 | 6.01 | 6.19 | 5.14 | 4.78 | 4.94 | 6.33 | 6.0 | 1.09 | 1.5mg/kg: 5078.90 | 31.60 | 1.03 | 0.12 | 0.16 | 0.18 | 1.85 | 30 | 97 | 25000 | 66 | 100 | 100 | 34 | E2 | |||||||||||||||
255 | IgG1 | 2.49e-11 | 2.01e-11 | 8.17e-09 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | <0.32 | 1 | 287 | 827 | 1.54e+01 | 7.56e+01 | 1.92e+02 | 30.0 | strong | weak | moderate | weak | weak | weak | moderate | 6.47 | 6.33 | 6.04 | 6.23 | 5.26 | 4.93 | 5.64 | 6.32 | 8.6 | 0.722 | del141|E682K | 1.5mg/kg: 3002.57 | 35.35 | 1.15 | 0.02 | 0.03 | 0.33 | 3.30 | 47 | 100 | 25000 | 66 | 85 | 100 | 48 | E2 | ||||||||||||||||||
256 | IgG1 | 4.49e-11 | 3.33e-11 | 5.64e-09 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 1 | 3 | >25000 | >25000 | 6.38e+00 | 1.29e+01 | 1.96e+01 | 50.0 | strong | weak | moderate | weak | weak | weak | weak | 6.49 | 6.31 | 6.07 | 6.3 | 5.4 | 4.99 | 5.22 | 6.32 | 7.0 | 0.887 | del241-247 | 1.5mg/kg: 1455.69 | 38.10 | 1.24 | 0.35 | 0.47 | 0.25 | 2.50 | 92 | 97 | 25000 | 94 | 100 | 90 | 93 | E2 | ||||||||||||||||||
257 | IgG1 | 2.24e-11 | 1.62e-11 | 2.19e-09 | 1.48e-10 | 30.3 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 1 | 3 | 1334 | 4193 | 5.79e+00 | 1.66e+01 | 3.07e+01 | 40.0 | strong | moderate | moderate | weak | weak | moderate | moderate | 6.5 | 6.17 | 6.06 | 6.19 | 5.43 | 4.77 | 5.05 | 6.35 | 0.5 | 0.468 | 0.5mg/kg: 248.87|1.5mg/kg: 1129.40 | 37.50 | 1.22 | 0.05 | 0.07 | 0.67 | 6.70 | 32 | 95 | 25000 | 49 | 89 | 96 | 33 | E2 | |||||||||||||||
258 | IgG1 | 1.29e-11 | 1.37e-11 | 1.24e-08 | 4.7e-10 | 118.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | <0.32 | 1 | >25000 | >25000 | 1.33e+01 | 5.98e+01 | 1.44e+02 | 70.0 | moderate | weak | weak | moderate | weak | weak | moderate | 6.45 | 6.0 | 5.91 | 6.0 | 5.03 | 4.75 | 5.07 | 6.3 | 6.1 | 0.382 | 1.5mg/kg: 903.31 | 30.85 | 1.00 | 0.04 | 0.05 | 0.35 | 3.50 | 51 | 100 | 25000 | 74 | 97 | 100 | 31 | E2 | |||||||||||||||
259 | IgG1 | 1 | 3.38e-11 | 2.13e-11 | 2.1e-09 | 1.1e-06 | 24.5 | 71.3 | 130.0 | >25000 | >25000 | >25000 | 8.06 | 42.1 | 96.2 | 2 | 9 | >25000 | >25000 | 5.74e+01 | 9.89e+01 | 1.36e+02 | 100.0 | strong | moderate | moderate | moderate | weak | moderate | moderate | 6.31 | 6.32 | 5.91 | 6.19 | 5.16 | 4.92 | 5.1 | 6.25 | 100.0 | 0.28 | E1195A|del375-377,P384L | 1.5mg/kg: 13172.90 | 35.75 | 1.16 | 0.12 | 0.16 | 1.02 | 10.25 | 1 | 97 | 8.06 | 0 | 90 | 96 | 93 | H1 | |||||||||||||
260 | IgG1 | 2c | 1.59e-11 | 1.07e-11 | 6.96e-11 | 5.87e-08 | 1.15e-08 | 9.37e-09 | 11.7 | 31.1 | 53.7 | >25000 | >25000 | >25000 | 66.4 | 325.0 | 831.0 | <0.32 | 2 | >25000 | >25000 | 1.83e+01 | 2.64e+01 | 3.27e+01 | 10.0 | strong | strong | moderate | moderate | weak | weak | weak | 6.36 | 6.54 | 6.24 | 6.66 | 5.67 | 4.69 | 5.06 | 6.22 | 100.0 | 1.61 | del450|del449|Y449D | 1.5mg/kg: 3179.28 | 39.00 | 1.27 | 0.58 | 0.77 | 0.20 | 2.00 | 1 | 100 | 66.4 | 2 | 9 | 4 | 90 | B | |||||||||||
261 | IgG1 | 5b | 2.23e-10 | 3.57e-10 | 2.78e-10 | 2.08e-07 | 1.34e-10 | 1.56e-09 | 4680.0 | 17800.0 | 24800.0 | >25000 | >25000 | >25000 | 449 | 2465 | 905 | 3490 | 5.08e+03 | 9.28e+03 | 1.32e+04 | 10.0 | strong | moderate | moderate | strong | weak | moderate | moderate | 6.23 | 6.24 | 5.92 | 5.99 | 4.61 | 4.74 | 5.13 | 6.14 | 30.9 | 2.99 | 1.5mg/kg: 5999.07 | 39.95 | 1.30 | 5.38 | 7.07 | 0.72 | 7.20 | 84 | 85 | 25000 | 75 | 73 | 78 | 68 | E4 | |||||||||||||||
262 | IgG1 | 4a | 2.65e-10 | 8.49e-11 | 4.67e-09 | 4.23e-06 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 39 | 185 | >25000 | >25000 | 2.65e+03 | 3.11e+03 | 3.42e+03 | strong | weak | moderate | strong | weak | weak | moderate | 6.41 | 6.61 | 6.17 | 6.55 | 5.47 | 4.97 | 5.09 | 6.27 | 100.0 | 3.21 | 44.65 | 1.45 | 0.81 | 1.07 | 0.04 | 0.40 | 57 | 100 | 25000 | 90 | 100 | 100 | 95 | H1 | |||||||||||||||||||
263 | IgG1 | 7b | 3.58e-10 | 2.16e-10 | 8.61e-11 | 1.07e-07 | 1.14e-10 | 2.72e-08 | 1180.0 | 3800.0 | 5200.0 | 803.0 | 1620.0 | 1990.0 | 244.0 | >25000 | >25000 | 232 | 683 | 7.47e+03 | 2.56e+04 | 5.26e+04 | 40.6 | 2.43 | 36.75 | 1.19 | 0.54 | 0.71 | 0.24 | 2.40 | 72 | 60 | 244 | 33 | 100 | 91 | 93 | C1 | |||||||||||||||||||||||||||||||
264 | IgG1 | 6.2e-11 | 4.42e-11 | 4.77e-08 | 6.67e-10 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | <0.32 | 2 | 13913 | >25000 | 5.30e+00 | 1.54e+01 | 2.88e+01 | moderate | weak | moderate | weak | weak | strong | strong | 6.4 | 6.12 | 5.87 | 5.85 | 4.88 | 4.6 | 5.01 | 6.32 | 6.3 | 2.38 | 32.25 | 1.05 | 0.70 | 0.93 | 0.38 | 3.80 | 68 | 100 | 25000 | 70 | 100 | 99 | 37 | E2 | ||||||||||||||||||||
265 | IgG1 | 2a | 3.68e-11 | 2.43e-11 | 1.55e-09 | 1.1e-06 | 4.76e-10 | 3.45e-08 | 12.2 | 41.7 | 80.8 | >25000 | >25000 | >25000 | 3.02 | 17.7 | 40.2 | <0.32 | 4 | 12587 | >25000 | 1.84e+01 | 3.21e+01 | 4.45e+01 | strong | strong | strong | weak | weak | strong | strong | 6.28 | 6.28 | 5.82 | 6.19 | 4.93 | 4.71 | 4.93 | 6.18 | 100.0 | 3.15 | A475D|F486L|N487D|E484A | 42.85 | 1.39 | 1.15 | 1.51 | 0.15 | 1.55 | 1 | 100 | 3.02 | 1 | 100 | 100 | 100 | H4 | |||||||||||||
266 | IgG1 | 2a | 8.43e-11 | 8.04e-11 | 2.41e-09 | 1.8e-06 | 4.48e-10 | 3.98e-08 | 18.7 | 60.6 | 116.0 | 90.0 | 366.0 | 1790.0 | 11.0 | 32.9 | 53.7 | 2 | 10 | 4.47e+01 | 9.16e+01 | 1.39e+02 | 60.0 | strong | strong | strong | weak | weak | moderate | moderate | 6.3 | 6.43 | 5.92 | 6.31 | 5.04 | 4.83 | 5.19 | 6.22 | 100.0 | 2.84 | 1.5mg/kg: 6491.44 | 36.85 | 1.20 | 0.35 | 0.47 | 0.23 | 2.30 | 1 | 18 | 11 | 1 | 88 | 99 | 100 | H4 | ||||||||||||||
267 | IgG1 | 2a | 5.28e-11 | 9.65e-11 | 1.95e-09 | 1.74e-06 | 7.31e-09 | 16.3 | 45.6 | 81.0 | >25000 | >25000 | >25000 | 4.95 | 16.2 | 29.9 | 1 | 4 | 2.13e+01 | 8.27e+01 | 1.83e+02 | 60.0 | moderate | moderate | moderate | strong | weak | moderate | moderate | 6.11 | 5.79 | 5.28 | 5.58 | 4.53 | 4.58 | 5.11 | 6.0 | 100.0 | 3.02 | S371F | 0.5mg/kg: 50.30|1.5mg/kg: 86.02 | 43.35 | 1.41 | 0.50 | 0.66 | 0.09 | 0.90 | 1 | 99 | 4.95 | 0 | 91 | 100 | 100 | H4 | ||||||||||||||
268 | IgG1 | 4b | 3.71e-11 | 2.06e-11 | 2.29e-09 | 1.9e-06 | 3.13e-11 | 1.37e-10 | 9.28 | 23.2 | 38.0 | 4.8 | 12.4 | 20.1 | >25000 | >25000 | >25000 | 10 | 25 | 2.19e+01 | 3.13e+01 | 3.85e+01 | 70.0 | moderate | weak | moderate | weak | weak | moderate | moderate | 5.12 | 5.35 | 3.87 | 3.66 | 6.0 | 4.65 | 4.88 | 5.71 | 100.0 | 5.6 | R444K|G447V|Y449C | 0.5mg/kg: 2053.25|1.5mg/kg: 6582.65 | 43.35 | 1.41 | 0.38 | 3.75 | 1 | 0 | 25000 | 3 | 74 | 100 | 0 | G | |||||||||||||||
269 | IgG1 | 2b | 2.03e-11 | 1.43e-11 | 7.99e-09 | 5.32e-06 | 1.35e-11 | 5.46e-09 | 51.5 | 151.0 | 282.0 | 28.8 | 128.0 | 316.0 | 637.0 | >25000 | >25000 | 11 | 26 | <0.32 | 14 | 2.82e+01 | 8.19e+01 | 1.53e+02 | 60.0 | weak | weak | moderate | weak | weak | moderate | moderate | 5.38 | 5.89 | 4.82 | 4.66 | 6.11 | 4.69 | 5.12 | 5.94 | 100.0 | 4.16 | F486I | 1.5mg/kg: 11318.93 | 45.00 | 1.46 | 7.36 | 9.68 | 0.52 | 5.15 | 3 | 7 | 637 | 5 | 90 | 95 | 83 | H2 | |||||||||||
270 | IgG1 | 2d | 9.77e-12 | 5.85e-12 | 4.49e-11 | 1.97e-08 | 1e-09 | 4.85e-08 | 8.53 | 18.5 | 28.3 | >25000 | >25000 | >25000 | 16.6 | 36.3 | 55.5 | 1 | 3 | >25000 | >25000 | 2.16e+01 | 5.10e+01 | 8.44e+01 | 0.0 | strong | strong | moderate | moderate | weak | moderate | moderate | 6.22 | 6.1 | 6.12 | 6.48 | 5.84 | 5.3 | 5.38 | 6.16 | 98.5 | 4.0 | 0.5mg/kg: 1401.83|1.5mg/kg: 4244.41 | 50.15 | 1.83 | 0.83 | 1.38 | 0.14 | 0.43 | 0 | 99 | 16.6 | 0 | 99 | 100 | 100 | H3 | ||||||||||||
271 | IgG1 | 2d | 1.7e-11 | 9.64e-12 | 1.12e-11 | 2.86e-09 | 1.51e-10 | 17.4 | 47.0 | 81.8 | 0.735 | 0.459 | 0.405 | 32.1 | 74.4 | 119.0 | 3 | 16 | 1624 | 3879 | 1.05e+02 | 1.50e+02 | 1.86e+02 | 30.0 | strong | strong | strong | strong | weak | moderate | moderate | 6.2 | 6.09 | 6.08 | 6.49 | 5.5 | 5.28 | 5.37 | 6.14 | 98.6 | 3.81 | 1.5mg/kg: 7760.50 | 48.45 | 1.77 | 0.73 | 1.21 | 0.09 | 0.28 | 0 | 94 | 32.1 | 0 | 98 | 92 | 100 | H2 | |||||||||||||
272 | IgG1 | 2c | 5.9e-11 | 4.42e-11 | 5.57e-09 | 4.63e-10 | 199.0 | 752.0 | 1360.0 | >25000 | >25000 | >25000 | 71.5 | 213.0 | 401.0 | 40 | 116 | 24668 | >25000 | 7.18e+02 | 1.62e+03 | 2.61e+03 | strong | moderate | moderate | moderate | weak | moderate | moderate | 6.08 | 6.01 | 5.66 | 6.38 | 5.42 | 5.21 | 5.31 | 6.05 | 97.2 | 1.3 | 38.55 | 1.41 | 0.85 | 1.41 | 0.24 | 0.72 | 5 | 92 | 71.5 | 2 | 92 | 100 | 98 | H3 | ||||||||||||||||
273 | IgG1 | 6b | 9.88e-11 | 8.88e-11 | 6.82e-10 | 5.22e-07 | 6.93e-11 | 21.8 | 83.7 | 170.0 | 62.8 | 154.0 | 249.0 | 21.8 | 52.1 | 86.2 | 4 | 15 | 9 | 24 | 1.26e+02 | 2.19e+02 | 3.03e+02 | 0.0 | moderate | weak | weak | moderate | weak | weak | weak | 4.77 | 6.02 | 4.09 | 4.42 | 4.49 | 3.72 | 4.79 | 5.91 | 100.0 | 0.859 | 1.5mg/kg: 2394.83 | 43.20 | 1.58 | 0.80 | 1.32 | 0.18 | 0.55 | 0 | 12 | 21.8 | 0 | 99 | 100 | 100 | A | |||||||||||||
274 | IgG1 | 6b | 8.54e-11 | 4.45e-11 | 7.78e-10 | 4.99e-07 | 6.57e-11 | 21.7 | 70.1 | 126.0 | 61.3 | 142.0 | 226.0 | 18.8 | 56.5 | 101.0 | 4 | 13 | 9 | 29 | 9.48e+01 | 1.62e+02 | 2.22e+02 | 60.0 | moderate | weak | weak | moderate | weak | weak | weak | 4.75 | 6.04 | 4.14 | 4.3 | 4.6 | 3.57 | 4.86 | 5.89 | 100.0 | 1.56 | 0.5mg/kg: 2349.99|1.5mg/kg: 8943.40 | 41.75 | 1.53 | 0.77 | 1.27 | 0.16 | 0.48 | 1 | 1 | 18.8 | 1 | 100 | 96 | 90 | A | |||||||||||||
275 | IgG2b | 2b | 1.37e-10 | 9.76e-11 | 1.18e-08 | 1.34e-11 | 6.86 | 22.2 | 40.4 | 3.24 | 12.3 | 20.0 | 98.6 | 362.0 | 695.0 | 3 | 6 | 1 | 4 | 4.81e+01 | 6.79e+01 | 8.30e+01 | 80.0 | moderate | moderate | moderate | moderate | moderate | weak | weak | 5.94 | 6.09 | 6.44 | 4.07 | 5.49 | 5.35 | 5.38 | 6.13 | 100.0 | 1.02 | 1.5mg/kg: 50.30 | 40.65 | 1.49 | 0.80 | 1.31 | 0.19 | 0.57 | 0 | 2 | 98.6 | 27 | 100 | 97 | 100 | H2 | ||||||||||||||
276 | IgG2b | 2b | 4.65e-10 | 9.3e-11 | 3.49e-09 | 1.75e-06 | 1.31e-11 | 2.72 | 8.67 | 14.9 | 0.959 | 2.8 | 5.24 | 13.1 | 42.2 | 82.2 | 18 | 40 | <0.32 | 2 | 5.70e+01 | 9.13e+01 | 1.20e+02 | 50.0 | moderate | moderate | moderate | strong | moderate | weak | weak | 5.98 | 6.17 | 6.8 | 4.02 | 5.57 | 5.33 | 5.39 | 6.12 | 100.0 | 1.02 | 1.5mg/kg: 50.30 | 35.85 | 1.31 | 1.72 | 2.83 | 0.47 | 1.39 | 0 | 1 | 13.1 | 1 | 100 | 99 | 100 | H2 | |||||||||||||
277 | IgG2a | 2d | 2.45e-10 | 1.68e-10 | 4.59e-09 | 2.32e-06 | 9.6e-10 | 9.18 | 28.9 | 52.6 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2 | 6 | >25000 | >25000 | 5.79e+01 | 9.13e+01 | 1.19e+02 | moderate | moderate | strong | strong | weak | weak | weak | 6.21 | 3.34 | 5.64 | 3.88 | 3.75 | 5.36 | 5.38 | 4.05 | 100.0 | 0.904 | 40.35 | 1.48 | 2.34 | 3.87 | 0.24 | 0.73 | 0 | 100 | 25000 | 100 | 100 | 100 | 100 | H3 | |||||||||||||||
278 | IgG1 | 4b | 5.36e-10 | 6.89e-11 | 1.47e-09 | 2.93e-07 | 1.77e-11 | 11.7 | 44.4 | 96.6 | 22.6 | 90.7 | 195.0 | >25000 | >25000 | >25000 | 5 | 16 | 2 | 20 | 8.91e+01 | 1.60e+02 | 2.26e+02 | 0.0 | moderate | weak | strong | strong | weak | weak | weak | 6.24 | 3.4 | 4.77 | 3.88 | 3.76 | 5.4 | 5.39 | 4.05 | 100.0 | 3.11 | 1.5mg/kg: 50.30 | 49.00 | 1.79 | 0.81 | 1.35 | 0.17 | 0.52 | 2 | 3 | 25000 | 100 | 100 | 100 | 81 | G | |||||||||||||
279 | IgG1 | 4b | 1.01e-10 | 5.72e-11 | 6.65e-10 | 2.4e-07 | 2.32e-11 | 10.3 | 29.5 | 54.5 | 15.3 | 45.5 | 87.7 | >25000 | >25000 | >25000 | 4 | 13 | 1 | 5 | 4.93e+01 | 1.25e+02 | 2.15e+02 | 10.0 | moderate | weak | moderate | strong | weak | weak | weak | 6.22 | 3.47 | 4.85 | 3.87 | 3.75 | 5.37 | 5.39 | 4.18 | 100.0 | 1.28 | 0.5mg/kg: 50.30|1.5mg/kg: 50.30|5mg/kg: 50.30 | 40.80 | 1.49 | 1.01 | 1.68 | 0.17 | 0.52 | 1 | 1 | 25000 | 100 | 2 | 6 | 2 | G | |||||||||||||
280 | IgG1 | 2b | 1.27e-09 | 1.72e-09 | 7.66e-09 | 2.03e-06 | 1.44e-10 | 29.1 | 85.6 | 155.0 | 19.3 | 46.9 | 77.7 | >25000 | >25000 | >25000 | 10 | 28 | 5 | 20 | 5.63e+01 | 1.11e+02 | 1.65e+02 | 0.0 | moderate | weak | moderate | strong | weak | weak | weak | 6.21 | 3.54 | 4.64 | 3.88 | 3.75 | 5.36 | 5.35 | 4.13 | 100.0 | 2.6 | 1.5mg/kg: 50.30 | 44.60 | 1.63 | 1.03 | 1.71 | 0.06 | 0.19 | 2 | 3 | 25000 | 100 | 100 | 97 | 100 | H4 | |||||||||||||
281 | IgG2b | 4b | 3.77e-10 | 3.39e-10 | 8.59e-09 | 3.34e-06 | 3.72e-11 | 120.0 | 379.0 | 756.0 | 634.0 | 2590.0 | 10300.0 | >25000 | >25000 | >25000 | 70 | 141 | 9 | 105 | 1.72e+02 | 4.49e+02 | 7.88e+02 | 10.0 | weak | strong | moderate | strong | moderate | weak | weak | 5.96 | 6.13 | 6.95 | 4.22 | 5.22 | 5.41 | 5.38 | 6.12 | 100.0 | 3.65 | 1.5mg/kg: 50.30 | 47.95 | 1.75 | 1.09 | 1.80 | 0.19 | 0.57 | 13 | 43 | 25000 | 100 | 80 | 24 | 26 | G | |||||||||||||
282 | IgG1 | 2d | 5.5e-10 | 4.32e-10 | 8.24e-09 | 2.96e-06 | 7.85e-09 | 47.1 | 150.0 | 288.0 | 8.67 | 2690.0 | 9430.0 | 0.848 | 0.837 | 0.834 | 7 | 58 | >25000 | >25000 | 5.39e+01 | 1.39e+02 | 2.42e+02 | moderate | weak | moderate | weak | weak | weak | weak | 6.22 | 3.73 | 4.84 | 3.94 | 3.78 | 5.38 | 5.39 | 4.61 | 100.0 | 5.6 | 44.55 | 1.63 | 0.87 | 1.44 | 0.18 | 0.55 | 3 | 100 | 0.848 | 100 | 100 | 100 | 100 | H3 | |||||||||||||||
283 | IgG2a | 6b | 1.02e-10 | 1.31e-10 | 6.51e-10 | 2.08e-07 | 7.79e-11 | 103.0 | 312.0 | 544.0 | 331.0 | 693.0 | 1140.0 | 74.8 | 204.0 | 343.0 | 80 | 167 | 360 | 710 | 1.82e+02 | 6.46e+02 | 1.35e+03 | 30.0 | moderate | strong | moderate | moderate | weak | weak | weak | 5.62 | 6.05 | 5.19 | 3.86 | 3.75 | 5.28 | 5.39 | 6.13 | 93.4 | 1.67 | 1.5mg/kg: 50.30 | 39.20 | 1.43 | 1.01 | 1.68 | 0.23 | 0.69 | 10 | 38 | 74.8 | 10 | 100 | 100 | 99 | A | |||||||||||||
284 | IgG2a | 6b | 2.99e-10 | 2.34e-10 | 5.48e-10 | 7.5e-08 | 8.18e-11 | 134.0 | 473.0 | 823.0 | 370.0 | 783.0 | 1210.0 | 95.7 | 248.0 | 416.0 | 37 | 116 | 121 | 459 | 2.65e+02 | 4.91e+02 | 7.03e+02 | 50.0 | moderate | strong | moderate | moderate | weak | weak | weak | 6.03 | 6.1 | 5.46 | 3.82 | 3.75 | 5.28 | 5.38 | 6.12 | 95.0 | 1.15 | 1.5mg/kg: 50.30 | 35.30 | 1.29 | 1.18 | 1.95 | 0.16 | 0.48 | 17 | 47 | 95.7 | 15 | 100 | 100 | 99 | A | |||||||||||||
285 | IgG2a | 2b | 3.57e-10 | 4.88e-10 | 2.3e-08 | 1.14e-10 | 254.0 | 844.0 | 2190.0 | 508.0 | >25000 | >25000 | 148.0 | 430.0 | 1460.0 | 18 | 38 | 15 | 38 | 1.45e+02 | 3.93e+02 | 7.06e+02 | 40.0 | moderate | strong | moderate | strong | moderate | weak | moderate | 6.13 | 6.13 | 6.38 | 4.02 | 3.78 | 5.25 | 5.38 | 6.13 | 100.0 | 1.16 | 1.5mg/kg: 50.30 | 46.05 | 1.68 | 0.97 | 1.61 | 0.13 | 0.39 | 35 | 49 | 148 | 14 | 84 | 87 | 98 | H2 | ||||||||||||||
286 | IgG2a | 3.99e-10 | 4.84e-10 | 1.1e-08 | 9.19e-11 | >25000 | >25000 | >25000 | 1470.0 | >25000 | >25000 | 144 | 482 | 4.36e+03 | 8.25e+03 | 1.20e+04 | 0.0 | strong | moderate | moderate | moderate | weak | weak | weak | 6.08 | 6.14 | 5.8 | 3.87 | 3.79 | 5.27 | 5.39 | 6.14 | 100.0 | 1.63 | 1.5mg/kg: 50.30 | 41.35 | 1.51 | 0.91 | 1.50 | 0.23 | 0.67 | 75 | 100 | 1470 | 57 | 100 | 89 | 96 | C3 | ||||||||||||||||||||
287 | IgG2a | 7c | 6.09e-10 | 6.51e-10 | 5.51e-10 | 6.35e-08 | 1.31e-10 | 712.0 | 9170.0 | >25000 | 2150.0 | 7590.0 | >25000 | 1250.0 | 2610.0 | 3160.0 | 121 | 333 | 3.72e+03 | 1.08e+04 | 2.02e+04 | 10.0 | strong | strong | moderate | moderate | weak | weak | moderate | 5.98 | 6.08 | 5.12 | 3.9 | 3.83 | 5.18 | 5.37 | 6.12 | 28.8 | 1.4 | 1.5mg/kg: 50.30 | 38.00 | 1.39 | 1.26 | 2.08 | 0.08 | 0.24 | 78 | 91 | 1250 | 79 | 100 | 100 | 100 | C3 | |||||||||||||||
288 | IgG1 | 2b | 3.08e-11 | 1.56e-11 | 1.83e-08 | 1.98e-11 | 4.48e-09 | 34.5 | 102.0 | 188.0 | 20.3 | 70.7 | 139.0 | 13.3 | 31.2 | 50.9 | 17 | 63 | 3 | 16 | 4.00e+01 | 4.98e+02 | 2.17e+03 | 80.0 | strong | weak | moderate | strong | weak | moderate | moderate | 6.03 | 5.97 | 5.39 | 6.46 | 6.36 | 4.65 | 5.21 | 6.11 | 100.0 | 1.27 | 1.5mg/kg: 7793.19 | 42.00 | 1.54 | 1.05 | 1.74 | 0.20 | 0.60 | 2 | 10 | 13.3 | 2 | 100 | 100 | 100 | H2 | |||||||||||||
289 | IgG1 | 2b | 3.56e-11 | 2.21e-11 | 2.83e-09 | 1.85e-06 | 1.82e-11 | 1.28e-09 | 4.5 | 12.1 | 21.2 | 6.54 | 19.5 | 28.8 | 5.06 | 13.6 | 22.2 | 0.63 | 2 | <0.32 | 2 | 1.71e+01 | 6.25e+01 | 1.33e+02 | 80.0 | moderate | moderate | moderate | moderate | weak | weak | weak | 5.66 | 6.11 | 4.62 | 6.24 | 6.41 | 5.06 | 5.33 | 6.19 | 100.0 | 0.975 | 1.5mg/kg: 6710.22 | 43.20 | 1.58 | 0.96 | 1.60 | 0.41 | 1.24 | 0 | 1 | 5.06 | 0 | 100 | 98 | 98 | H2 | ||||||||||||
290 | IgG1 | 2b | 2.49e-11 | 1.82e-11 | 3.26e-10 | 2.23e-07 | 1.63e-11 | 1.92e-09 | 5.73 | 13.0 | 20.4 | 3.46 | 10.3 | 17.2 | 1.84 | 6.91 | 11.2 | 1 | 3 | <0.32 | 0.81 | 1.97e+01 | 4.13e+01 | 6.38e+01 | 10.0 | strong | strong | strong | strong | weak | moderate | weak | 6.2 | 6.1 | 6.15 | 6.45 | 5.6 | 5.28 | 5.37 | 6.14 | 100.0 | 2.94 | 5mg/kg: 43196.02 | 45.85 | 1.68 | 1.19 | 1.97 | 0.10 | 0.30 | 1 | 0 | 1.84 | 0 | 2 | 0 | 0 | H2 | ||||||||||||
291 | IgG1 | 5a | 3.67e-11 | 2.25e-11 | 6.83e-09 | 2.86e-06 | 2.4e-11 | 3.5e-10 | 2.74 | 5.69 | 8.04 | 2.25 | 5.82 | 9.57 | >25000 | >25000 | >25000 | <0.32 | 1 | <0.32 | 0.51 | 1.93e+01 | 4.84e+01 | 8.29e+01 | 90.0 | strong | moderate | moderate | strong | moderate | moderate | moderate | 6.17 | 6.1 | 6.23 | 6.46 | 5.69 | 5.25 | 5.38 | 6.15 | 100.0 | 0.755 | 1.5mg/kg: 7254.11 | 38.00 | 1.39 | 0.96 | 1.59 | 0.15 | 0.46 | 0 | 0 | 25000 | 1 | 48 | 56 | 44 | E1 | ||||||||||||
292 | IgG1 | 2b | 1.9e-11 | 1.59e-11 | 6.71e-09 | 1.89e-06 | 2.6e-11 | 3.54e-09 | 5.22 | 13.3 | 22.7 | 7.99 | 28.3 | 59.6 | 0.844 | 3.88 | 6.18 | 1 | 3 | 3 | 18 | 2.27e+01 | 4.78e+01 | 7.40e+01 | 70.0 | strong | weak | moderate | moderate | weak | weak | weak | 6.14 | 6.08 | 6.45 | 6.46 | 5.76 | 5.33 | 5.37 | 6.13 | 100.0 | 2.59 | 1.5mg/kg: 6138.10 | 43.95 | 1.61 | 0.77 | 1.26 | 0.16 | 0.48 | 0 | 0 | 0.844 | 0 | 5 | 6 | 7 | H2 | ||||||||||||
293 | IgG1 | 2b | 1.8e-11 | 2.83e-11 | 4.29e-10 | 3.2e-07 | 5.76e-11 | 8.53e-09 | 3.16 | 11.3 | 23.3 | 11.8 | 46.7 | 101.0 | 2.67 | 9.21 | 14.2 | <0.32 | 0.44 | 6 | 34 | 6.17e+01 | 9.73e+01 | 1.27e+02 | 20.0 | strong | moderate | moderate | strong | moderate | moderate | weak | 6.08 | 6.08 | 5.83 | 6.37 | 5.85 | 5.24 | 5.34 | 6.13 | 100.0 | 0.931 | 1.5mg/kg: 5656.25 | 39.00 | 1.43 | 1.29 | 2.13 | 0.19 | 0.57 | 1 | 2 | 2.67 | 2 | 34 | 27 | 38 | H2 | ||||||||||||
294 | IgG1 | 2a | 4.9e-11 | 2.2e-11 | 5.93e-11 | 2.34e-08 | 1.36e-10 | 1.3e-09 | 7.19 | 25.7 | 52.0 | 23.7 | 106.0 | 228.0 | 16.8 | 36.5 | 55.5 | <0.32 | 7 | 31 | 108 | 1.07e+02 | 2.02e+02 | 2.93e+02 | 20.0 | weak | weak | weak | moderate | weak | weak | weak | 3.07 | 3.39 | 4.12 | 3.91 | 3.72 | 3.04 | 4.02 | 3.89 | 99.2 | 2.48 | 1.5mg/kg: 8561.64 | 41.40 | 1.51 | 1.09 | 1.80 | 0.15 | 0.46 | 1 | 1 | 16.8 | 1 | 2 | 2 | 0 | H4 | ||||||||||||
295 | IgG1 | 4b | 4.85e-11 | 3.02e-11 | 2.66e-10 | 1.48e-07 | 2.66e-11 | 1.62e-10 | 21.7 | 45.8 | 69.8 | 13.1 | 38.2 | 70.5 | 425.0 | 1590.0 | >25000 | 3 | 7 | <0.32 | 3 | 1.49e+02 | 3.32e+02 | 5.29e+02 | 30.0 | moderate | strong | strong | strong | moderate | weak | moderate | 6.19 | 6.11 | 6.54 | 6.48 | 5.84 | 5.38 | 5.39 | 6.19 | 78.0 | 0.818 | 1.5mg/kg: 6903.83 | 41.70 | 1.52 | 1.05 | 1.74 | 0.20 | 0.61 | 0 | 1 | 425 | 10 | 3 | 2 | 2 | G | ||||||||||||
296 | IgG1 | 2a | 1.99e-10 | 5.09e-11 | 5.01e-10 | 2.26e-07 | 3.68e-10 | 5.25e-08 | 27.9 | 76.2 | 136.0 | 298.0 | 1030.0 | 1580.0 | 23.2 | 57.0 | 93.6 | 21 | 45 | 883 | 2607 | 3.07e+02 | 4.88e+02 | 6.40e+02 | 20.0 | moderate | moderate | strong | weak | weak | moderate | weak | 6.1 | 6.09 | 5.71 | 6.44 | 5.06 | 5.24 | 5.35 | 6.13 | 98.1 | 3.04 | 1.5mg/kg: 4867.01 | 47.25 | 1.73 | 0.94 | 1.55 | 0.10 | 0.30 | 100 | 97 | 23.2 | 100 | 100 | 100 | 91 | H4 | ||||||||||||
297 | IgG1 | 2a | 1.33e-10 | 4.2e-11 | 2.71e-10 | 4.48e-08 | 1.88e-10 | 5.22e-08 | 23.4 | 61.0 | 106.0 | 89.6 | 410.0 | 779.0 | 26.6 | 61.5 | 95.2 | 3 | 10 | 88 | 362 | 3.01e+02 | 5.29e+02 | 7.36e+02 | 10.0 | strong | strong | strong | weak | weak | weak | weak | 6.1 | 6.08 | 5.81 | 6.41 | 5.28 | 5.2 | 5.35 | 6.12 | 96.3 | 0.641 | 1.5mg/kg: 3367.14 | 39.80 | 1.46 | 0.85 | 1.40 | 0.36 | 1.09 | 2 | 13 | 26.6 | 4 | 99 | 69 | 100 | H4 | ||||||||||||
298 | IgG1 | 5b | 6.48e-10 | 2.08e-10 | 6.29e-10 | 3.75e-07 | 1.66e-10 | 4.51e-09 | 135.0 | 509.0 | 865.0 | 1070.0 | >25000 | >25000 | 162.0 | 494.0 | 873.0 | 266 | 589 | 7.30e+00 | 1.84e+01 | 3.15e+01 | 10.0 | strong | moderate | strong | weak | moderate | weak | weak | 6.17 | 6.11 | 5.59 | 6.41 | 5.26 | 5.26 | 5.37 | 6.19 | 100.0 | 3.08 | 1.5mg/kg: 4520.88 | 46.55 | 1.70 | 1.09 | 1.80 | 0.14 | 0.43 | 28 | 82 | 162 | 42 | 100 | 100 | 84 | E4 | ||||||||||||||
299 | IgG1 | 2a | 9.55e-11 | 6.3e-11 | 3.32e-10 | 5.44e-08 | 3.84e-11 | 5.69e-09 | 33.2 | 75.5 | 125.0 | 10.2 | 38.0 | 77.2 | 37.2 | 89.5 | 142.0 | 16 | 34 | 2 | 15 | 1.66e+01 | 2.56e+01 | 3.30e+01 | 0.0 | strong | moderate | strong | weak | weak | weak | weak | 6.11 | 6.05 | 5.47 | 6.39 | 5.16 | 5.23 | 5.35 | 6.12 | 95.6 | 2.67 | 1.5mg/kg: 5342.70 | 52.10 | 1.90 | 6.61 | 10.93 | 3 | 1 | 37.2 | 5 | 7 | 2 | 4 | H2 | ||||||||||||||
300 | IgG1 | 2c | 6.25e-11 | 2.79e-11 | 1.13e-09 | 2.31e-06 | 6.06e-09 | 5.2 | 14.3 | 24.3 | >25000 | >25000 | >25000 | 38.3 | 94.3 | 158.0 | <0.32 | <0.32 | >25000 | >25000 | 2.59e+02 | 4.10e+02 | 5.35e+02 | 50.0 | strong | moderate | strong | weak | moderate | moderate | weak | 6.19 | 6.09 | 6.17 | 6.47 | 5.75 | 5.25 | 5.34 | 6.14 | 100.0 | 0.0836 | 1.5mg/kg: 10980.54 | 43.55 | 1.59 | 0.90 | 1.48 | 0.15 | 0.46 | 1 | 100 | 38.3 | 12 | 100 | 100 | 100 | H3 | |||||||||||||
301 | IgG1 | 2a | 8.45e-11 | 4.74e-11 | 1.55e-09 | 3.7e-07 | 6.78e-10 | 2.79e-07 | 15.6 | 52.1 | 92.2 | >25000 | >25000 | >25000 | 29.5 | 60.9 | 90.6 | 5 | 21 | <0.32 | 5 | 2.08e+02 | 6.60e+02 | 1.30e+03 | 10.0 | strong | moderate | strong | weak | weak | weak | weak | 6.05 | 6.08 | 6.34 | 6.43 | 5.52 | 5.29 | 5.35 | 6.14 | 100.0 | 2.08 | 1.5mg/kg: 6742.59 | 35.30 | 1.29 | 1.05 | 1.74 | 0.09 | 0.27 | 1 | 98 | 29.5 | 4 | 100 | 100 | 100 | H4 | ||||||||||||
302 | IgG1 | 2a | 4.99e-11 | 3.94e-11 | 4.16e-10 | 1.29e-07 | 4.55e-11 | 1.93e-08 | 41.5 | 168.0 | 345.0 | 68.3 | 268.0 | 558.0 | 64.6 | 165.0 | 290.0 | 23 | 82 | 29 | 111 | 5.28e+02 | 9.67e+02 | 1.38e+03 | 0.0 | strong | moderate | strong | moderate | weak | weak | weak | 5.93 | 5.97 | 5.05 | 6.27 | 4.76 | 5.07 | 5.26 | 6.05 | 97.9 | 1.13 | 1.5mg/kg: 2481.20 | 36.70 | 1.34 | 2.06 | 3.40 | 0.44 | 1.31 | 29 | 38 | 64.6 | 7 | 60 | 45 | 46 | H4 | ||||||||||||
303 | IgG1 | 6a | 3.75e-09 | 2.95e-09 | 1.77e-08 | 1.37e-09 | 8.96e-08 | 1750.0 | >25000 | >25000 | >25000 | >25000 | >25000 | 3860.0 | >25000 | >25000 | 8853 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | weak | weak | moderate | weak | weak | weak | 4.85 | 5.36 | 4.08 | 4.32 | 3.76 | 3.73 | 4.42 | 5.59 | 100.0 | 0.924 | 99 | 88 | 3860 | 60 | 97 | 90 | 84 | A | |||||||||||||||||||||||
304 | IgG1 | 4a | 2.37e-10 | 1.23e-10 | 1.97e-07 | 1.22e-07 | 2.32e-10 | 1.03e-09 | 976.0 | 11300.0 | >25000 | >25000 | >25000 | >25000 | 0.0631 | 0.033 | 0.0276 | 42 | 461 | >25000 | >25000 | 2.40e+03 | 2.59e+04 | 1.04e+05 | weak | weak | weak | moderate | weak | weak | moderate | 3.1 | 3.37 | 4.11 | 3.84 | 3.7 | 3.03 | 4.06 | 3.94 | 100.0 | 1.12 | 40.85 | 1.49 | 1.02 | 1.69 | 0.23 | 0.67 | 50 | 93 | 0.0631 | 1 | 90 | 86 | 68 | I | ||||||||||||||
305 | IgG1 | 5b | 3.38e-09 | 1.58e-09 | 7.27e-09 | 1.69e-09 | 8.25e-09 | 2520.0 | 2580.0 | 2600.0 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | weak | weak | weak | weak | weak | weak | moderate | 3.11 | 3.46 | 4.17 | 3.87 | 3.71 | 3.02 | 4.03 | 4.73 | 72.6 | 0.136 | 38.85 | 1.42 | 0.73 | 1.21 | 0.21 | 0.63 | 94 | 91 | 25000 | 13 | 86 | 100 | 81 | E4 | ||||||||||||||||||||
306 | IgG1 | 2c | 1.01e-09 | 5.36e-10 | 2.63e-08 | 3.83e-08 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 1593 | 3256 | 2.50e+04 | 2.50e+04 | 2.50e+04 | weak | weak | weak | weak | weak | moderate | moderate | 3.08 | 3.45 | 4.14 | 3.84 | 3.69 | 3.02 | 4.07 | 3.86 | 100.0 | 1.33 | 38.10 | 1.39 | 0.83 | 1.37 | 0.12 | 0.36 | 42 | 88 | 25000 | 11 | 100 | 90 | 85 | B | |||||||||||||||||||||
307 | IgG1 | 2b | 2e-11 | 2.46e-11 | 2.36e-09 | 8.45e-07 | 8.95e-12 | 6.51e-09 | 5.83 | 14.3 | 23.9 | 9.67 | 38.7 | 92.2 | 122.0 | 594.0 | 1250.0 | <0.32 | 3 | <0.32 | 1 | 3.34e+01 | 5.10e+01 | 6.53e+01 | 60.0 | strong | strong | strong | weak | weak | moderate | moderate | 6.19 | 6.09 | 6.0 | 6.47 | 5.79 | 5.29 | 5.38 | 6.14 | 100.0 | 2.76 | 1.5mg/kg: 9720.63 | 47.15 | 1.72 | 2.03 | 3.36 | 0.01 | 0.01 | 1 | 3 | 122 | 11 | 97 | 93 | 90 | H2 | ||||||||||||
308 | IgG1 | 4b | 2.3e-11 | 2.83e-11 | 3.7e-10 | 1.39e-07 | 1.56e-11 | 5.41e-10 | 8.75 | 20.9 | 32.2 | 117.0 | 733.0 | >25000 | >25000 | >25000 | >25000 | <0.32 | <0.32 | 4 | 27 | 2.98e+01 | 4.23e+01 | 5.20e+01 | 70.0 | moderate | strong | moderate | weak | weak | moderate | moderate | 6.19 | 6.11 | 6.23 | 6.49 | 5.77 | 5.31 | 5.39 | 6.16 | 91.0 | 4.9 | 1.5mg/kg: 8929.00 | 48.10 | 1.76 | 1.54 | 2.55 | 0.01 | 0.03 | 1 | 27 | 25000 | 18 | 100 | 89 | 6 | G | ||||||||||||
309 | IgG1 | 6a | 2.23e-11 | 3.25e-11 | 1.68e-10 | 8.44e-08 | 1.18e-10 | 2.12e-08 | 6.4 | 35.2 | 103.0 | 1700.0 | 20100.0 | >25000 | 30.5 | 80.8 | 138.0 | <0.32 | 7 | 683 | 1928 | 7.36e+01 | 1.27e+02 | 1.74e+02 | moderate | weak | moderate | weak | weak | strong | strong | 6.14 | 6.07 | 5.02 | 6.4 | 4.63 | 5.04 | 5.34 | 6.13 | 99.3 | 3.08 | 47.95 | 1.75 | 1.20 | 1.98 | 0.18 | 0.55 | 1 | 66 | 30.5 | 2 | 100 | 97 | 86 | B | ||||||||||||||
310 | IgG1 | 2b | 2.19e-11 | 3.97e-11 | 1.85e-09 | 1.57e-06 | 1.21e-11 | 1.12e-08 | 3.39 | 8.94 | 13.9 | 9.31 | 43.6 | 101.0 | 601.0 | 2450.0 | 3820.0 | <0.32 | <0.32 | 0.32 | 5 | 3.31e+01 | 4.29e+01 | 4.99e+01 | 10.0 | moderate | moderate | strong | weak | moderate | strong | strong | 6.16 | 6.11 | 6.44 | 6.45 | 5.46 | 5.18 | 5.37 | 6.19 | 100.0 | 4.77 | 1.5mg/kg: 5169.00 | 48.85 | 1.79 | 1.08 | 1.79 | 0.12 | 0.37 | 2 | 4 | 601 | 46 | 100 | 86 | 91 | H2 | ||||||||||||
311 | IgG1 | 2b | 5.78e-11 | 5.7e-11 | 3.03e-09 | 1.76e-11 | 2.21e-08 | 3.39 | 9.17 | 16.6 | 54.2 | 221.0 | 488.0 | 3000.0 | 5700.0 | 6620.0 | <0.32 | 2 | 14 | 61 | 1.83e+01 | 2.54e+01 | 3.08e+01 | 20.0 | moderate | moderate | strong | weak | moderate | strong | strong | 6.18 | 6.1 | 5.95 | 6.43 | 5.52 | 5.24 | 5.37 | 6.24 | 94.2 | 2.45 | 1.5mg/kg: 3885.39 | 42.60 | 1.56 | 0.74 | 1.22 | 0.13 | 0.39 | 1 | 4 | 3000 | 86 | 100 | 100 | 91 | H2 | |||||||||||||
312 | IgG1 | 4b | 3.28e-11 | 4.1e-11 | 3.47e-10 | 2.02e-07 | 2.09e-11 | 7.84e-10 | 2.73 | 6.42 | 8.99 | 3.37 | 7.69 | 12.7 | 49.9 | 212.0 | 497.0 | <0.32 | <0.32 | <0.32 | <0.32 | 1.10e+01 | 1.27e+01 | 1.38e+01 | 0.0 | moderate | moderate | moderate | moderate | moderate | strong | strong | 6.12 | 6.09 | 6.18 | 6.46 | 5.55 | 5.31 | 5.37 | 6.15 | 100.0 | 3.03 | 1.5mg/kg: 7230.67 | 45.00 | 1.65 | 0.85 | 1.41 | 0.16 | 0.48 | 1 | 0 | 49.9 | 7 | 61 | 100 | 12 | H2 | ||||||||||||
313 | IgG1 | 4b | 3.01e-11 | 3.62e-11 | 1.55e-10 | 1.21e-07 | 2.83e-11 | 7.29e-10 | 3.62 | 8.78 | 12.2 | 2.52 | 7.22 | 12.8 | 53.2 | 162.0 | 316.0 | <0.32 | <0.32 | <0.32 | <0.32 | 9.58e+00 | 1.10e+01 | 1.19e+01 | 20.0 | strong | moderate | moderate | strong | moderate | strong | strong | 6.17 | 6.11 | 6.34 | 6.47 | 5.7 | 5.37 | 5.38 | 6.17 | 100.0 | 1.86 | 0.5mg/kg: 774.42|1.5mg/kg: 4277.45 | 37.25 | 1.37 | 0.81 | 1.07 | 0.94 | 0.84 | 1 | 0 | 53.2 | 6 | 42 | 100 | 3 | H2 | ||||||||||||
314 | IgG1 | 7a | 1.29e-10 | 2.03e-10 | 2.28e-08 | 5.7e-11 | 4.06e-09 | 2.16 | 11.8 | 21.5 | 1.85 | 7.04 | 14.7 | 1.54 | 4.17 | 6.35 | <0.32 | 3 | <0.32 | 5 | 4.77e+01 | 5.55e+01 | 6.07e+01 | 0.0 | moderate | weak | weak | strong | moderate | moderate | moderate | 5.91 | 6.01 | 4.68 | 6.14 | 4.04 | 5.04 | 5.29 | 6.09 | 100.0 | 3.24 | 1.5mg/kg: 50.30 | 46.45 | 1.71 | 0.64 | 0.85 | 0.73 | 0.66 | 1 | 0 | 1.54 | 1 | 1 | 0 | 96 | C1 | |||||||||||||
315 | IgG1 | 7a | 5.58e-10 | 1.58e-10 | 4.45e-08 | 4.89e-11 | 1.39e-08 | 0.429 | 3.44 | 7.53 | 1.05 | 3.75 | 8.21 | 0.677 | 1.7 | 3.13 | <0.32 | <0.32 | <0.32 | 3 | 3.27e+01 | 5.03e+01 | 6.47e+01 | moderate | moderate | weak | weak | moderate | weak | weak | 5.76 | 5.94 | 4.15 | 6.03 | 3.86 | 4.62 | 5.08 | 6.03 | 99.1 | 2.38 | 37.00 | 1.37 | 0.73 | 0.98 | 0.66 | 0.59 | 2 | 0 | 0.677 | 0 | 0 | 1 | 78 | C1 | |||||||||||||||
316 | IgG1 | 7a | 5.53e-11 | 1.57e-10 | 3.41e-08 | 8.85e-11 | 1.45e-09 | 0.802 | 4.24 | 10.2 | 0.334 | 1.61 | 3.02 | <0.32 | <0.32 | 2 | 4 | 1.56e+01 | 2.91e+01 | 4.19e+01 | moderate | moderate | weak | strong | moderate | moderate | moderate | 5.74 | 5.91 | 4.11 | 6.02 | 3.77 | 4.49 | 5.01 | 5.98 | 99.2 | 2.61 | 44.50 | 1.64 | 0.97 | 1.30 | 0.50 | 0.45 | 1 | 0 | 0.334 | 0 | 2 | 1 | 73 | C1 | ||||||||||||||||||
317 | IgG1 | 7a | 1.4e-10 | 4.31e-10 | 4.13e-08 | 7.21e-11 | 1.77e-08 | 0.518 | 2.58 | 5.74 | 0.949 | 4.99 | 11.7 | 0.672 | 1.86 | 3.72 | <0.32 | <0.32 | <0.32 | 4 | 2.78e+01 | 4.40e+01 | 5.74e+01 | moderate | weak | weak | moderate | weak | moderate | moderate | 4.72 | 5.68 | 4.09 | 3.95 | 3.75 | 3.07 | 4.16 | 5.92 | 94.1 | 2.27 | 39.70 | 1.46 | 0.83 | 1.11 | 0.94 | 0.84 | 1 | 0 | 0.672 | 1 | 0 | 1 | 75 | C1 | |||||||||||||||
318 | IgG1 | 7a | 5.05e-09 | 5.47e-10 | 5.87e-08 | 2.11e-10 | 6.92e-08 | 97.7 | 485.0 | 1960.0 | 57.4 | 194.0 | 365.0 | 350.0 | 2100.0 | >25000 | 42 | 120 | 48 | 120 | 7.18e+02 | 1.22e+03 | 1.66e+03 | moderate | moderate | moderate | weak | weak | moderate | moderate | 5.69 | 5.95 | 4.11 | 6.32 | 3.74 | 4.23 | 4.97 | 6.04 | 92.8 | 1.75 | 10 | 1 | 350 | 2 | 27 | 13 | 73 | A | |||||||||||||||||||||
319 | IgG1 | 7a | 4.86e-10 | 7.16e-10 | 3.09e-08 | 5.39e-11 | 1.93e-08 | 6.75 | 30.0 | 59.7 | 3.42 | 13.2 | 27.7 | 35.0 | 59.9 | 102.0 | 4 | 21 | 11 | 32 | 3.27e+02 | 4.42e+02 | 5.27e+02 | strong | moderate | weak | weak | weak | strong | strong | 5.85 | 5.92 | 4.16 | 6.28 | 3.81 | 4.07 | 4.98 | 6.0 | 99.4 | 1.96 | 39.05 | 1.44 | 0.88 | 1.17 | 0.78 | 0.70 | 2 | 0 | 35 | 0 | 1 | 1 | 91 | B | |||||||||||||||
320 | IgG1 | 7a | 1.76e-10 | 5.23e-10 | 3.07e-08 | 1.13e-10 | 4.47e-09 | 2.03 | 11.0 | 19.2 | 2.64 | 7.81 | 14.4 | 12.2 | 20.7 | 31.6 | 1 | 16 | 15 | 29 | 5.46e+01 | 6.58e+01 | 7.33e+01 | 0.0 | strong | moderate | moderate | weak | weak | strong | strong | 5.99 | 6.0 | 4.9 | 6.32 | 4.28 | 5.02 | 5.32 | 6.07 | 100.0 | 3.5 | 1.5mg/kg: 50.30 | 43.80 | 1.62 | 0.59 | 0.79 | 0.54 | 0.48 | 1 | 0 | 12.2 | 0 | 3 | 1 | 77 | C1 | |||||||||||||
321 | IgG1 | 7a | 1.79e-10 | 6.5e-10 | 3e-08 | 9.51e-11 | 3.93e-09 | 3.34 | 11.6 | 22.1 | 2.59 | 9.26 | 18.7 | 10.1 | 13.4 | 16.4 | 3 | 11 | 16 | 34 | 5.52e+01 | 8.78e+01 | 1.15e+02 | moderate | weak | weak | weak | weak | moderate | moderate | 5.39 | 5.84 | 4.14 | 4.55 | 3.85 | 3.72 | 4.74 | 6.05 | 100.0 | 2.02 | 0.5mg/kg: 50.30 | 39.55 | 1.46 | 0.43 | 0.57 | 0.54 | 0.48 | 1 | 0 | 10.1 | 0 | 1 | 1 | 1 | C1 | ||||||||||||||
322 | IgG1 | 7a | 1.32e-10 | 6.64e-10 | 3.02e-08 | 4.5e-11 | 5.09e-09 | 5.18 | 24.2 | 54.8 | 4.89 | 15.5 | 28.2 | 6.92 | 22.3 | 43.5 | 13 | 47 | 19 | 69 | 7.11e+01 | 1.13e+02 | 1.48e+02 | moderate | moderate | weak | weak | weak | moderate | moderate | 5.54 | 5.89 | 4.18 | 4.53 | 3.83 | 3.87 | 4.8 | 6.06 | 100.0 | 3.31 | 44.85 | 1.65 | 0.69 | 0.92 | 0.60 | 0.54 | 3 | 0 | 6.92 | 0 | 3 | 1 | 49 | C1 | |||||||||||||||
323 | IgG1 | 4c | 7.91e-11 | 4.88e-11 | 2.5e-09 | 1.07e-06 | 2.41e-11 | 2.56e-10 | 61.0 | 319.0 | 816.0 | 40.9 | 259.0 | 622.0 | >25000 | >25000 | >25000 | 41 | 253 | 1 | 6 | 7.33e+02 | 2.66e+03 | 5.66e+03 | 0.0 | moderate | moderate | moderate | moderate | weak | moderate | moderate | 6.31 | 6.2 | 5.84 | 6.2 | 5.27 | 5.41 | 5.43 | 6.23 | 94.9 | 2.66 | 1.5mg/kg: 10493.43|5mg/kg: 50117.28 | 43.35 | 1.60 | 0.65 | 0.87 | 0.68 | 0.61 | 32 | 12 | 25000 | 100 | 30 | 95 | 6 | G | ||||||||||||
324 | IgG1 | 4c | 7.34e-10 | 6.49e-10 | 1.13e-08 | 1.78e-10 | 7.02e-09 | >25000 | >25000 | >25000 | 17500.0 | >25000 | >25000 | 10448 | 19929 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 0.0 | moderate | moderate | weak | moderate | weak | weak | weak | 6.14 | 6.1 | 5.14 | 6.01 | 4.61 | 5.22 | 5.36 | 6.13 | 100.0 | 2.5 | 5mg/kg: 3822.42 | 37.35 | 1.38 | 0.87 | 1.16 | 0.57 | 0.51 | 100 | 97 | 17500 | 100 | 100 | 100 | 4 | G | ||||||||||||||||||
325 | IgG1 | 2a | 1.99e-10 | 7.69e-11 | 4.19e-09 | 2.51e-10 | 7.5e-09 | 1410.0 | 5500.0 | 9140.0 | >25000 | >25000 | >25000 | 610.0 | 3690.0 | 6820.0 | 203 | 1423 | 4.45e+03 | 7.63e+03 | 1.05e+04 | moderate | moderate | weak | strong | weak | weak | moderate | 6.16 | 6.08 | 5.73 | 6.07 | 5.05 | 5.27 | 5.38 | 6.12 | 100.0 | 1.86 | 38.70 | 1.43 | 1.18 | 1.57 | 1.15 | 1.02 | 66 | 100 | 610 | 35 | 100 | 100 | 92 | B | |||||||||||||||||
326 | IgG1 | 2c | 3.25e-10 | 8.29e-11 | 1.77e-07 | 5.96e-10 | 1.08e-09 | 350.0 | 1120.0 | 1710.0 | >25000 | >25000 | >25000 | 7.02 | 20.5 | 38.7 | 12 | 71 | 1816 | 4617 | 1.21e+03 | 1.79e+03 | 2.26e+03 | 60.0 | moderate | weak | moderate | moderate | weak | moderate | strong | 6.19 | 6.13 | 5.61 | 6.06 | 5.15 | 5.35 | 5.42 | 6.19 | 100.0 | 1.49 | 5mg/kg: 23384.78 | 35.05 | 1.29 | 1.24 | 1.65 | 0.72 | 0.65 | 26 | 90 | 7.02 | 0 | 16 | 15 | 23 | H2 | |||||||||||||
327 | IgG1 | 5b | 1.04e-09 | 1.18e-09 | 2.3e-07 | 1.15e-09 | 4.17e-09 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | moderate | weak | moderate | weak | strong | weak | 6.02 | 6.07 | 5.79 | 5.85 | 3.9 | 4.98 | 5.31 | 6.14 | 57.3 | 1.63 | 34.75 | 1.28 | 0.89 | 1.19 | 0.97 | 0.87 | 99 | 93 | 25000 | 62 | 96 | 88 | 78 | E4 | ||||||||||||||||||||
328 | IgG1 | 5b | 6.58e-10 | 6.76e-10 | 9.87e-08 | 7.06e-10 | 7.18e-09 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | weak | weak | moderate | weak | weak | weak | 6.16 | 6.13 | 4.83 | 5.99 | 4.19 | 5.29 | 5.37 | 6.19 | 54.9 | 2.16 | 43.30 | 1.60 | 0.66 | 0.87 | 0.54 | 0.48 | 96 | 97 | 25000 | 55 | 91 | 87 | 82 | E4 | ||||||||||||||||||||
329 | IgG1 | 5.91e-09 | 3.45e-09 | 4.45e-09 | 4.11e-09 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | moderate | weak | weak | weak | weak | weak | moderate | 4.79 | 4.96 | 4.36 | 4.1 | 3.78 | 3.71 | 4.44 | 5.35 | 9.8 | 0.605 | 34.75 | 1.28 | 1.15 | 1.53 | 0.49 | 0.44 | 92 | 95 | 25000 | 58 | 90 | 88 | 75 | E3 | ||||||||||||||||||||||
330 | IgG1 | 7a | 1.4e-09 | 1.88e-09 | 6.1e-07 | 1.49e-09 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | weak | moderate | weak | weak | weak | weak | moderate | 5.56 | 5.9 | 4.37 | 5.36 | 3.79 | 4.64 | 5.12 | 6.01 | 82.9 | 1.22 | 32.95 | 1.22 | 1.06 | 1.41 | 0.62 | 0.56 | 96 | 89 | 25000 | 94 | 96 | 85 | 70 | C3 | |||||||||||||||||||||
331 | IgG1 | 2a | 5.95e-11 | 2.58e-11 | 7.04e-11 | 4.05e-08 | 4.4e-11 | 2.65e-08 | 12.5 | 42.2 | 81.2 | 17.2 | 65.9 | 130.0 | 20.2 | 75.3 | 150.0 | 16 | 44 | 8 | 22 | 8.81e+01 | 1.32e+02 | 1.68e+02 | 0.0 | strong | moderate | moderate | weak | weak | weak | weak | 6.29 | 6.16 | 5.55 | 6.19 | 5.14 | 5.37 | 5.41 | 6.21 | 91.8 | 1.17 | 1.5mg/kg: 9781.65 | 35.60 | 1.31 | 0.90 | 1.20 | 0.61 | 0.54 | 1 | 1 | 20.2 | 3 | 77 | 70 | 48 | H4 | ||||||||||||
332 | IgG1 | 2a | 2.34e-11 | 1.04e-11 | 1.11e-10 | 7.69e-08 | 3.26e-11 | 4.84 | 18.7 | 38.5 | 25.9 | 82.0 | 272.0 | 13.1 | 40.5 | 71.4 | 1 | 3 | <0.32 | 2 | 1.75e+01 | 3.75e+01 | 5.85e+01 | 60.0 | strong | moderate | moderate | weak | weak | weak | moderate | 6.27 | 6.19 | 5.62 | 6.21 | 5.53 | 5.39 | 5.43 | 6.23 | 99.3 | 2.24 | 1.5mg/kg: 11249.88 | 38.00 | 1.40 | 0.72 | 0.96 | 0.73 | 0.66 | 1 | 6 | 13.1 | 1 | 94 | 90 | 95 | H2 | |||||||||||||
333 | IgG1 | 2b | 1.24e-11 | 6.4e-12 | 1.11e-11 | 1.77e-08 | 1.52e-11 | 1.93e-11 | 4.0 | 10.3 | 17.6 | 3.14 | 8.88 | 17.0 | 3.92 | 11.7 | 21.6 | <0.32 | <0.32 | <0.32 | <0.32 | 1.12e+01 | 1.32e+01 | 1.46e+01 | 80.0 | strong | moderate | strong | moderate | weak | weak | moderate | 6.37 | 6.22 | 5.99 | 6.27 | 5.64 | 5.39 | 5.45 | 6.24 | 97.4 | 0.774 | 1.5mg/kg: 9583.62 | 35.15 | 1.30 | 0.67 | 0.89 | 0.66 | 0.59 | 0 | 0 | 3.92 | 0 | 1 | 1 | 0 | H2 | ||||||||||||
334 | IgG1 | 2b | 1.51e-11 | 7.39e-12 | 5.68e-11 | 3.6e-08 | 8.67e-12 | 7.71e-11 | 3.72 | 11.0 | 19.3 | 2.23 | 5.34 | 9.03 | 3.7 | 9.19 | 13.3 | <0.32 | <0.32 | <0.32 | 2.42e+01 | 3.83e+01 | 5.01e+01 | 90.0 | strong | strong | strong | moderate | weak | weak | moderate | 6.3 | 6.19 | 6.17 | 6.22 | 5.6 | 5.38 | 5.43 | 6.23 | 100.0 | 2.84 | 1.5mg/kg: 12203.69 | 49.00 | 1.81 | 1.20 | 1.60 | 0.78 | 0.70 | 1 | 0 | 3.7 | 0 | 5 | 6 | 4 | H2 | |||||||||||||
335 | IgG1 | 5a | 1.64e-10 | 2.4e-11 | 9e-09 | 3.05e-06 | 1.78e-11 | 1.2e-08 | 6.94 | 19.8 | 35.4 | 7.78 | 23.2 | 44.7 | 6.41 | 19.7 | 36.1 | <0.32 | 1 | <0.32 | <0.32 | 6.29e+01 | 1.41e+02 | 2.27e+02 | 100.0 | strong | moderate | moderate | moderate | weak | moderate | moderate | 6.3 | 6.23 | 6.33 | 6.27 | 5.7 | 5.39 | 5.45 | 6.24 | 100.0 | 2.31 | 1.5mg/kg: 6860.78 | 41.00 | 1.51 | 1.30 | 1.74 | 1.39 | 1.24 | 1 | 2 | 6.41 | 1 | 100 | 99 | 80 | G | ||||||||||||
336 | IgG1 | 5d | 3.73e-11 | 1.15e-11 | 2.14e-09 | 7.68e-07 | 1.04e-11 | 9.27e-10 | 2.94 | 6.58 | 11.5 | 2.14 | 6.03 | 9.59 | 1.07 | 4.12 | 9.13 | <0.32 | 1 | <0.32 | 1 | 2.16e+01 | 3.53e+01 | 4.71e+01 | 70.0 | strong | moderate | strong | moderate | weak | moderate | moderate | 6.33 | 6.21 | 6.21 | 6.24 | 5.81 | 5.45 | 5.45 | 6.25 | 100.0 | 1.83 | 1.5mg/kg: 4844.32 | 42.00 | 1.55 | 1.15 | 1.53 | 0.46 | 0.41 | 1 | 1 | 1.07 | 0 | 100 | 93 | 1 | G | ||||||||||||
337 | IgG1 | 4b | 2.81e-11 | 7.33e-12 | 3.02e-09 | 1.21e-06 | 1.23e-11 | 5.74e-09 | 6.16 | 17.1 | 31.0 | 16.7 | 65.1 | 152.0 | >25000 | >25000 | >25000 | <0.32 | <0.32 | <0.32 | <0.32 | 6.94e+01 | 1.16e+02 | 1.57e+02 | 100.0 | strong | moderate | moderate | moderate | weak | weak | weak | 6.33 | 6.21 | 6.49 | 6.27 | 5.75 | 5.41 | 5.45 | 6.24 | 100.0 | 1.2 | 1.5mg/kg: 9485.93 | 37.95 | 1.40 | 0.73 | 0.98 | 0.57 | 0.51 | 1 | 10 | 25000 | 43 | 100 | 100 | 11 | G | ||||||||||||
338 | IgG1 | 4c | 2.36e-11 | 1.35e-11 | 6.64e-12 | 3.1e-09 | 4.37e-11 | 4.89e-10 | 10.9 | 42.9 | 89.0 | 69.8 | >25000 | >25000 | 83.3 | 285.0 | 703.0 | <0.32 | 9 | 12 | 63 | 9.20e+01 | 6.51e+02 | 2.05e+03 | 10.0 | strong | weak | strong | strong | weak | weak | weak | 6.27 | 6.18 | 5.75 | 6.08 | 5.53 | 5.44 | 5.43 | 6.24 | 74.9 | 1.0 | 1.5mg/kg: 8664.69 | 36.10 | 1.33 | 0.84 | 1.13 | 1.33 | 1.19 | 3 | 38 | 83.3 | 4 | 33 | 56 | 14 | G | ||||||||||||
339 | IgG1 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 30.0 | weak | weak | moderate | moderate | weak | strong | strong | 4.17 | 4.13 | 4.41 | 3.76 | 3.8 | 3.67 | 5.3 | 4.66 | 11.5 | 1.06 | 1.5mg/kg: 50.30 | 38.05 | 1.40 | 1.94 | 2.58 | 1.50 | 1.34 | 95 | 92 | 25000 | 85 | 100 | 96 | 78 | |||||||||||||||||||||||||
340 | IgG1 | 1.56e-08 | 555.0 | 1790.0 | 2480.0 | 73.7 | 579.0 | 1040.0 | >25000 | >25000 | >25000 | 23910 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 0.0 | weak | weak | moderate | strong | weak | strong | strong | 4.23 | 4.1 | 4.53 | 3.75 | 3.78 | 3.64 | 4.4 | 4.56 | 1.4 | 0.941 | 1.5mg/kg: 50.30|5mg/kg: 50.30 | 32.85 | 1.21 | 1.25 | 1.66 | 0.52 | 0.46 | 100 | 88 | 25000 | 77 | 95 | 82 | 76 | |||||||||||||||||||||
341 | IgG1 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 18581 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 0.0 | weak | weak | moderate | moderate | weak | moderate | moderate | 4.31 | 4.35 | 4.3 | 3.76 | 3.78 | 3.64 | 4.4 | 4.78 | 2.8 | 0.542 | 1.5mg/kg: 50.30|5mg/kg: 50.30 | 32.75 | 1.21 | 0.93 | 1.23 | 0.56 | 0.50 | 100 | 89 | 25000 | 87 | 100 | 85 | 60 | |||||||||||||||||||||||||
342 | IgG1 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 0.0 | weak | weak | weak | moderate | weak | moderate | moderate | 4.04 | 3.92 | 4.33 | 3.71 | 3.8 | 3.63 | 4.4 | 4.44 | 23.5 | 0.608 | 1.5mg/kg: 50.30|5mg/kg: 50.30 | 32.90 | 1.21 | 1.59 | 2.13 | 1.41 | 1.26 | 89 | 88 | 25000 | 87 | 96 | 79 | 68 | |||||||||||||||||||||||||
343 | IgG1 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 10.0 | weak | weak | weak | weak | weak | weak | weak | 4.04 | 3.92 | 4.36 | 3.73 | 3.8 | 3.57 | 4.37 | 4.38 | 0.522 | 1.5mg/kg: 50.30|5mg/kg: 50.30 | 39.10 | 1.44 | 1.03 | 1.37 | 0.44 | 0.39 | 100 | 92 | 25000 | 86 | 100 | 93 | 74 | ||||||||||||||||||||||||||
344 | IgG1 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 0.0 | weak | moderate | weak | weak | weak | weak | moderate | 4.05 | 3.86 | 4.33 | 3.75 | 3.79 | 3.59 | 4.39 | 4.31 | 1.5 | 0.688 | 1.5mg/kg: 50.30|5mg/kg: 50.30 | 45.25 | 1.67 | 0.88 | 1.17 | 0.56 | 0.50 | 100 | 85 | 25000 | 87 | 99 | 78 | 69 | |||||||||||||||||||||||||
345 | IgG1 | 3.98e-11 | 1.81e-11 | 1.77e-09 | 2.1e-08 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | <0.32 | <0.32 | >25000 | >25000 | 8.26e+01 | 2.36e+02 | 4.38e+02 | strong | weak | weak | moderate | weak | weak | moderate | 6.24 | 6.13 | 5.47 | 6.15 | 5.4 | 5.18 | 5.4 | 6.17 | 4.7 | 0.678 | 42.05 | 1.55 | 0.77 | 1.03 | 1.26 | 1.12 | 41 | 97 | 25000 | 76 | 62 | 96 | 74 | E2 | ||||||||||||||||||||
346 | IgG1 | 3.12e-11 | 1.44e-11 | 2.1e-09 | 2.38e-11 | 63.3 | 453.0 | 935.0 | 278.0 | 940.0 | 1600.0 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 8.4 | 56 | 72 | 25000 | 78 | 98 | 100 | 78 | E3 | |||||||||||||||||||||||||||||||||||||||||||
347 | IgG1 | 9.76e-10 | 6.76e-10 | 5.49e-09 | 3.28e-10 | 4.25e-09 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 10.2 | 100 | 97 | 25000 | 96 | 100 | 88 | 75 | C2 | |||||||||||||||||||||||||||||||||||||||||||||
348 | IgG1 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 100 | 100 | 25000 | 100 | 100 | 100 | 95 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
349 | IgG1 | 2.84e-09 | 1.04e-09 | 1.26e-07 | 29.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 1 | 5 | >25000 | >25000 | 1.42e+02 | 3.45e+02 | 5.82e+02 | moderate | moderate | weak | moderate | weak | weak | moderate | 5.95 | 5.92 | 4.55 | 5.75 | 4.19 | 4.84 | 5.22 | 6.01 | 29.1 | 0.749 | 40.10 | 1.48 | 0.90 | 1.19 | 1.04 | 0.93 | 42 | 100 | 25000 | 100 | 100 | 100 | 91 | E2 | ||||||||||||||||||
350 | IgG1 | 1.73e-09 | 9.89e-10 | 2.32e-08 | 3.29e-08 | 250.0 | >25000 | >25000 | 928.0 | >25000 | >25000 | >25000 | >25000 | >25000 | 20 | 88 | 9099 | 18089 | 3.42e+02 | 2.09e+03 | 6.04e+03 | moderate | strong | moderate | moderate | weak | weak | moderate | 5.32 | 5.61 | 4.34 | 4.71 | 3.92 | 3.87 | 4.62 | 5.77 | 29.4 | 0.654 | 42.15 | 1.56 | 0.81 | 1.09 | 0.69 | 0.62 | 40 | 96 | 25000 | 92 | 100 | 91 | 90 | E3 | |||||||||||||||||
351 | IgG1 | 2d | 4.42e-11 | 1.05e-11 | 6.96e-09 | 3.22e-06 | 4.62 | 11.8 | 19.7 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | <0.32 | <0.32 | 4.54e+01 | 5.29e+01 | 5.78e+01 | 90.0 | strong | moderate | strong | weak | weak | weak | weak | 6.33 | 6.2 | 6.5 | 6.28 | 5.77 | 5.45 | 5.46 | 6.25 | 100.0 | 0.366 | 1.5mg/kg: 10845.63 | 45.70 | 1.69 | 0.69 | 0.92 | 0.72 | 0.64 | 1 | 95 | 25000 | 84 | 100 | 97 | 82 | H3 | ||||||||||||||||
352 | IgG1 | 2d | 1.69e-11 | 9e-12 | 1.95e-08 | 11.4 | 44.3 | 89.3 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | <0.32 | <0.32 | 8.40e+01 | 1.57e+02 | 2.27e+02 | 90.0 | 100.0 | 0.81 | 1.5mg/kg: 14084.70 | 24.25 | 1.13 | 0.24 | 0.79 | 0.06 | 0.83 | 3 | 99 | 25000 | 97 | 100 | 88 | 73 | H3 | ||||||||||||||||||||||||||||||||
353 | IgG1 | 2d | 7.85e-11 | 2.08e-11 | 1.39e-08 | 5.31e-06 | 24.4 | 57.6 | 83.0 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | <0.32 | <0.32 | 1.81e+02 | 2.06e+02 | 2.22e+02 | strong | strong | moderate | moderate | weak | weak | weak | 6.26 | 6.2 | 6.24 | 6.14 | 5.75 | 5.45 | 5.45 | 6.24 | 100.0 | 0.954 | 23.10 | 1.08 | 0.18 | 0.61 | 0.10 | 1.50 | 4 | 96 | 25000 | 96 | 100 | 86 | 83 | H3 | ||||||||||||||||||
354 | IgG | 2b | 4.89e-11 | 1.78e-11 | 5.1e-10 | 2e-07 | 1.13e-11 | 8.5e-10 | 21.2 | 81.1 | 163.0 | 15.3 | 83.1 | 203.0 | 33.4 | 126.0 | 262.0 | <0.32 | 1 | 7.36e+01 | 9.81e+01 | 1.16e+02 | 20.0 | strong | moderate | strong | moderate | weak | strong | weak | 6.28 | 6.19 | 5.65 | 6.17 | 5.4 | 5.42 | 5.46 | 6.25 | 100.0 | 0.818 | 1.5mg/kg: 10050.93 | 23.95 | 1.12 | 0.30 | 1.00 | 0.10 | 1.46 | 1 | 2 | 33.4 | 2 | 13 | 17 | 20 | H2 | ||||||||||||||
355 | IgG1 | 5d | 8.13e-11 | 2.15e-11 | 1.25e-08 | 5.15e-06 | 1.72e-11 | 2.62e-10 | 4.97 | 18.7 | 39.8 | 3.25 | 11.3 | 22.9 | 1.87 | 36.4 | 90.3 | 3.85e+01 | 7.50e+01 | 1.11e+02 | 100.0 | 100.0 | 1.5mg/kg: 6120.14 | 22.90 | 1.07 | 0.40 | 1.30 | 0.12 | 1.85 | 3 | 1 | 1.87 | 2 | 84 | 69 | 10 | G | ||||||||||||||||||||||||||||||||
356 | IgG1 | 2b | 4.55e-11 | 1.22e-11 | 1.06e-08 | 4.29e-06 | 3.02e-10 | 1.25e-08 | 6.12 | 52.2 | 123.0 | 2250.0 | 19800.0 | >25000 | 44.1 | 279.0 | 793.0 | 9.06e+01 | 2.16e+02 | 3.59e+02 | 100.0 | 100.0 | 1.5mg/kg: 13940.55 | 21.25 | 0.99 | 0.28 | 0.93 | 0.02 | 0.36 | 1 | 86 | 44.1 | 12 | 100 | 93 | 72 | H2 | ||||||||||||||||||||||||||||||||
357 | IgG1 | 2a | 1.39e-10 | 4.26e-11 | 1.74e-08 | 5.15e-06 | 3.42e-09 | 8.2e-08 | 39.6 | 140.0 | 264.0 | >25000 | >25000 | >25000 | 8.86 | 9.3 | 9.75 | 1.63e+02 | 6.41e+02 | 1.43e+03 | 80.0 | 100.0 | 1.5mg/kg: 9425.66 | 28.95 | 1.35 | 0.09 | 0.29 | 0.32 | 4.81 | 4 | 97 | 8.86 | 0 | 100 | 93 | 77 | H4 | ||||||||||||||||||||||||||||||||
358 | IgG1 | 4.94e-10 | 1.94e-10 | 6.57e-08 | 4.7e-08 | 1740.0 | >25000 | >25000 | >25000 | >25000 | >25000 | 2170.0 | 6080.0 | 7920.0 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 0.0 | 1.5mg/kg: 602.05 | 27.90 | 1.30 | 0.17 | 0.57 | 0.20 | 3.01 | 79 | 72 | 2170 | 99 | 100 | 81 | 78 | E2 | ||||||||||||||||||||||||||||||||||||
359 | IgG1 | 2a | 3.6e-11 | 1.77e-11 | 1.39e-11 | 4.86e-09 | 6.13e-11 | 1.33e-09 | 9.03 | 21.2 | 34.4 | 17.7 | 57.1 | 120.0 | 17.0 | 38.7 | 61.6 | 6.88e+01 | 1.34e+02 | 1.97e+02 | 30.0 | 95.1 | 1.5mg/kg: 6131.03 | 21.50 | 1.00 | 0.24 | 0.79 | 0.09 | 1.28 | 1 | 4 | 17 | 0 | 11 | 5 | 2 | H2 | ||||||||||||||||||||||||||||||||
360 | IgG1 | 2a | 5.29e-11 | 1.68e-11 | 1.32e-11 | 8.06e-09 | 1.15e-11 | 2.31e-10 | 7.22 | 22.1 | 39.7 | 2.8 | 7.46 | 12.6 | 16.8 | 34.1 | 50.3 | 6.76e+01 | 1.42e+02 | 2.19e+02 | 50.0 | 97.2 | 1.5mg/kg: 7398.47 | 23.40 | 1.09 | 0.23 | 0.75 | 0.08 | 1.23 | 2 | 0 | 16.8 | 2 | 2 | 5 | 4 | H2 | ||||||||||||||||||||||||||||||||
361 | IgG1 | 2a | 1.1e-10 | 2.95e-11 | 2.41e-11 | 1.25e-08 | 1.86e-11 | 3e-10 | 12.3 | 42.5 | 83.6 | 5.28 | 17.7 | 35.6 | 19.2 | 51.3 | 91.5 | 5.76e+01 | 1.80e+02 | 3.50e+02 | 30.0 | 94.9 | 1.5mg/kg: 6513.45 | 22.80 | 1.06 | 0.28 | 0.93 | 0.06 | 0.90 | 2 | 1 | 19.2 | 3 | 4 | 2 | 2 | H2 | ||||||||||||||||||||||||||||||||
362 | IgG1 | 2a | 3.29e-11 | 9.64e-12 | 9.85e-12 | 4.3e-09 | 1.15e-11 | 2.1e-10 | 6.45 | 18.8 | 34.5 | 1.6 | 5.97 | 11.3 | 14.3 | 29.1 | 42.8 | 3.51e+01 | 6.43e+01 | 9.18e+01 | 20.0 | 96.4 | 1.5mg/kg: 10972.59 | 23.25 | 1.08 | 0.29 | 0.97 | 0.16 | 2.41 | 1 | 0 | 14.3 | 2 | 1 | 1 | 0 | H2 | ||||||||||||||||||||||||||||||||
363 | IgG1 | 5.77e-10 | 5.62e-10 | 2.87e-09 | 9.03e-10 | 3.91e-09 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 10.0 | 1.5mg/kg: 857.23 | 22.85 | 1.07 | 0.27 | 0.87 | 0.07 | 1.13 | 100 | 73 | 25000 | 100 | 100 | 90 | 86 | E3 | ||||||||||||||||||||||||||||||||||||||
364 | IgG1 | 1.75e-09 | 7.51e-10 | 1.97e-08 | 3.27e-10 | 2.38e-10 | 27.5 | 77.0 | 145.0 | 60.5 | 217.0 | 411.0 | >25000 | >25000 | >25000 | 2.80e+02 | 7.50e+02 | 1.33e+03 | 90.0 | 1.5mg/kg: 256.70 | 21.50 | 1.00 | 0.30 | 1.00 | 0.10 | 1.50 | 8 | 10 | 25000 | 100 | 7 | 7 | 65 | E3 | |||||||||||||||||||||||||||||||||||
365 | IgG1 | 2.2e-11 | 1.14e-11 | 3.02e-10 | 1.56e-10 | 11.1 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | >25000 | 2.69e+01 | 7.46e+01 | 1.36e+02 | 60.0 | 1.5mg/kg: 2297.93 | 21.20 | 0.99 | 0.33 | 1.08 | 0.06 | 0.83 | 30 | 82 | 25000 | 42 | 100 | 93 | 22 | E2 | ||||||||||||||||||||||||||||||||||||
366 | IgG1 | 7b | 1.09e-10 | 9.51e-11 | 7.03e-11 | 4.02e-08 | 5.33e-11 | 1.28e-08 | 200.0 | 818.0 | 2210.0 | 232.0 | 693.0 | 915.0 | 210.0 | 627.0 | 867.0 | 1.24e+03 | 1.89e+03 | 2.42e+03 | 0.0 | 81.7 | 1.5mg/kg: 6151.03 | 22.80 | 1.06 | 0.26 | 0.84 | 0.12 | 1.80 | 35 | 40 | 210 | 15 | 100 | 85 | 76 | C3 | ||||||||||||||||||||||||||||||||
367 | IgG1 | 4c | 7.01e-11 | 1.54e-11 | 3.01e-11 | 1.82e-08 | 1.04e-10 | 8.64e-10 | 35.3 | 127.0 | 332.0 | >25000 | >25000 | >25000 | 312.0 | 2530.0 | >25000 | 3.46e+02 | 1.22e+03 | 2.54e+03 | 70.0 | 45.3 | 1.5mg/kg: 8775.66 | 21.65 | 1.01 | 0.29 | 0.97 | 0.05 | 0.71 | 7 | 69 | 312 | 36 | 66 | 73 | 32 | G | ||||||||||||||||||||||||||||||||
368 | IgG1 | 3b | 2.71e-11 | 1.45e-11 | 4.36e-10 | 1.98e-07 | 1.12e-11 | 2.08e-10 | 3.6 | 10.7 | 18.1 | 2.69 | 7.77 | 13.5 | 2.26 | 7.47 | 14.9 | 3.49e+01 | 6.33e+01 | 8.98e+01 | 70.0 | 100.0 | 1.5mg/kg: 5925.57 | 23.30 | 1.09 | 0.24 | 0.79 | 0.10 | 1.58 | 1 | 0 | 2.26 | 0 | 0 | 2 | 0 | A | ||||||||||||||||||||||||||||||||
369 | IgG1 | 2a | 7.51e-10 | 1.66e-10 | 2.09e-10 | 3.1e-08 | 4.29e-11 | 7.64e-09 | 157.0 | 498.0 | 868.0 | 18.1 | 65.7 | 125.0 | 91.2 | 345.0 | 610.0 | 1.48e+03 | 2.47e+03 | 3.34e+03 | 0.0 | 79.0 | 1.5mg/kg: 2943.18 | 26.80 | 1.25 | 0.11 | 0.36 | 0.41 | 6.09 | 24 | 4 | 91.2 | 19 | 35 | 17 | 34 | B | ||||||||||||||||||||||||||||||||
370 | IgG1 | 4a | 2.24e-11 | 2.67e-11 | 1.16e-10 | 6.56e-08 | 1.17e-10 | 1.33e-08 | 1.33e+01 | 1.56e+01 | 1.70e+01 | 10.0 | 99.6 | 1.5mg/kg: 20815.20 | 26.30 | 1.23 | 0.02 | 0.07 | 0.14 | 2.11 | 1 | 16 | nt | 10 | 17 | 20 | 22 | H2 | |||||||||||||||||||||||||||||||||||||||||
371 | IgG1 | 4a | 4.5e-11 | 3.24e-11 | 1.17e-09 | 3.36e-07 | 2.24e-11 | 1.94e-10 | 1.64e+01 | 2.32e+01 | 2.83e+01 | 0.0 | 100.0 | 1.5mg/kg: 7301.76|5mg/kg: 4452.89 | 24.45 | 1.14 | 0.24 | 0.80 | 0.07 | 0.98 | 0 | 1 | nt | 1 | 1 | 2 | 1 | H3 | |||||||||||||||||||||||||||||||||||||||||
372 | IgG1 | 3.36e-11 | 8.24e-11 | 9.16e-11 | 9.52e-08 | 8.46e-11 | 3.91e-10 | 2.84e+03 | 1.67e+04 | 4.71e+04 | 0.0 | 86.8 | 1.5mg/kg: 8461.38 | 17 | 40 | nt | 27 | 100 | 49 | 79 | A | ||||||||||||||||||||||||||||||||||||||||||||||||
373 | IgG1 | 3.06e-11 | 7.94e-11 | 5.89e-11 | 5.81e-08 | 6.92e-11 | 5.62e-10 | 2.54e+03 | 1.10e+04 | 2.61e+04 | 0.0 | 89.0 | 1.5mg/kg: 7693.29 | 16 | 35 | nt | 20 | 72 | 59 | 86 | A | ||||||||||||||||||||||||||||||||||||||||||||||||
374 | IgG1 | 7.83e+00 | 1.18e+01 | 1.50e+01 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
375 | IgG1 | 7.41e+00 | 1.67e+01 | 2.68e+01 | 60.0 | 1.5mg/kg: 9131.97 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
376 | IgG1 | 9.23e+00 | 1.69e+01 | 2.42e+01 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
377 | IgG1 | 6.19e+00 | 3.21e+01 | 8.43e+01 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
378 | IgG1 | 1.67e+01 | 6.21e+01 | 1.34e+02 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
379 | IgG1 | 1.02e+01 | 2.21e+01 | 3.49e+01 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
380 | IgG1 | 9.69e+00 | 3.95e+01 | 9.00e+01 | 50.0 | 1.5mg/kg: 7762.41 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
381 | IgG1 | 3.53e+00 | 1.84e+01 | 4.84e+01 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
382 | IgG1 | 8.08e+00 | 2.15e+01 | 3.82e+01 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
383 | IgG1 | 9.45e+00 | 2.42e+01 | 4.19e+01 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
384 | IgG1 | 6.68e-11 | 2.79e-10 | 2.84e-10 | 1.92e-10 | 2.84e+03 | 2.47e+04 | 8.77e+04 | 10.0 | 1.5mg/kg: 8284.68 | 92 | 99 | nt | 100 | 100 | 89 | 100 | E3 | |||||||||||||||||||||||||||||||||||||||||||||||||||
385 | IgG1 | 2.47e-11 | 2.93e-11 | 3.27e-11 | 2.21e-08 | 1.88e-11 | 3.45e-11 | 6.35e+01 | 9.62e+01 | 1.23e+02 | 10.0 | 98.2 | 1.5mg/kg: 5621.77 | 1 | 0 | nt | 0 | 1 | 0 | 0 | H2 | ||||||||||||||||||||||||||||||||||||||||||||||||
386 | IgG1 | 2.71e-11 | 3.47e-11 | 1.77e-10 | 9.15e-08 | 1.96e-11 | 4.33e-10 | 3.28e+01 | 6.63e+01 | 1.00e+02 | 0.0 | 99.4 | 1.5mg/kg: 6160.13 | 0 | 0 | nt | 1 | 0 | 1 | 0 | G | ||||||||||||||||||||||||||||||||||||||||||||||||
387 | IgG | 7.79e-10 | 1.33e-09 | 2.32e-09 | 5.58e-09 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 0.0 | 3.3 | 1.5mg/kg: 50.30 | 92 | 90 | nt | 100 | 95 | 91 | 87 | E3 | ||||||||||||||||||||||||||||||||||||||||||||||||||
388 | IgG | 9.63e-10 | 3.96e-09 | 3.75e-09 | 1.04e-08 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 0.0 | 11.1 | 1.5mg/kg: 50.30 | 98 | 92 | nt | 100 | 88 | 88 | 87 | E3 | ||||||||||||||||||||||||||||||||||||||||||||||||||
389 | IgG | 2.8e-09 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 10.0 | 1.5mg/kg: 50.30 | 94 | 86 | nt | 100 | 74 | 88 | 83 | E3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
390 | IgG | 6e-10 | 8.67e-10 | 1.3e-09 | 2.50e+04 | 2.50e+04 | 2.50e+04 | 3.4 | 100 | 93 | nt | 100 | 100 | 88 | 87 | E3 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
391 | IgG | 6.3e-11 | 1.44e-10 | 1.98e-11 | 9.23e-09 | 2.1e-10 | 8.47e-10 | 1.52e+03 | 4.87e+03 | 9.65e+03 | 80.0 | 4.0 | 1.5mg/kg: 10918.63 | 38 | 69 | nt | 93 | 65 | 64 | 61 | G | ||||||||||||||||||||||||||||||||||||||||||||||||
392 | IgG1 | 2.3e-11 | 3.41e-11 | 8.71e-11 | 1.85e-08 | 2.1e-11 | 1.01e-10 | 2.63e+01 | 6.56e+01 | 1.12e+02 | 0.0 | 95.2 | 1.5mg/kg: 12855.33 | 1 | 2 | nt | 1 | 4 | 8 | 14 | H2 | ||||||||||||||||||||||||||||||||||||||||||||||||
393 | IgG1 | 2.8e-11 | 3.24e-11 | 2.33e-10 | 9.01e-08 | 2.82e-11 | 2.64e-10 | 3.51e+01 | 8.04e+01 | 1.31e+02 | 30.0 | 99.0 | 1.5mg/kg: 12002.49 | 1 | 1 | nt | 1 | 1 | 1 | 1 | G | ||||||||||||||||||||||||||||||||||||||||||||||||
394 | IgG1 | 1.18e-10 | 2.82e-10 | 1.44e-08 | 2.15e-11 | 4.55e-09 | 2.99e+02 | 5.18e+02 | 7.15e+02 | 100.0 | 1 | 1 | nt | 0 | 50 | 100 | 40 | H4 | |||||||||||||||||||||||||||||||||||||||||||||||||||
395 | IgG1 | 9.01e-11 | 2.14e-10 | 1.67e-08 | 2.9e-11 | 1.22e-09 | 2.75e+02 | 5.11e+02 | 7.35e+02 | 100.0 | 1 | 6 | nt | 0 | 21 | 14 | 24 | H4 | |||||||||||||||||||||||||||||||||||||||||||||||||||
396 | IgG1 | 2.12e-11 | 7.66e-11 | 2.83e-11 | 4.7e-09 | 3.24e-11 | 8.46e-10 | 1.63e+04 | 3.47e+04 | 5.39e+04 | 36.4 | 93 | 94 | nt | 95 | 94 | 90 | 88 | |||||||||||||||||||||||||||||||||||||||||||||||||||
397 | IgG1 | 6.97e-12 | 8.74e-12 | 6.51e-11 | 3.36e-08 | 1.38e-11 | 1.07e-10 | 1.39e+01 | 2.14e+01 | 2.75e+01 | 99.2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
398 | IgG1 | 1.16e-11 | 3.97e-11 | 4.7e-11 | 2.84e-10 | 1.04e+04 | 1.82e+04 | 2.52e+04 | 6.9 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
399 | IgG1 | 1.11e-10 | 4.47e-10 | 2.4e-10 | 2.05e-09 | 2.50e+04 | 2.87e+04 | 6.14e+04 | 10.6 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
400 | IgG1 | 1.56e-10 | 4.62e-10 | 6.21e-10 | 2.73e-09 | 2.50e+04 | 2.13e+02 | 2.25e+02 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
401 | IgG1 | 1.04e-11 | 4.14e-11 | 5.18e-11 | 3.37e-10 | 2.50e+04 | 2.10e+01 | 2.07e+01 | 16.2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
402 | IgG1 | 1.07e-11 | 2.93e-11 | 5.09e-11 | 2.27e-08 | 6.45e-11 | 2.69e-10 | 2.16e+02 | 1.57e+03 | 5.01e+03 | 7.4 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
403 | IgG1 | 8.06e-12 | 9.8e-12 | 9.72e-11 | 4.15e-08 | 7.42e-12 | 1.58e-09 | 1.04e+01 | 2.72e+01 | 4.78e+01 | 100.0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
404 | IgG1 | 1.23e-11 | 1.68e-11 | 2.1e-10 | 7.94e-08 | 1.53e-11 | 1.88e-08 | 1.55e+01 | 2.21e+01 | 2.71e+01 | 99.2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
405 | IgG1 | 4.91e-11 | 2.46e-11 | 8.83e-10 | 5.7e-09 | 5.68e+01 | 4.09e+02 | 1.30e+03 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
406 | IgG1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
407 | IgG1 |
blocking
non-blocking
self